| Entry |
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| Name |
4-chlorophenylacetate 3,4-dioxygenase
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| Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
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| Sysname |
4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating)
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| Reaction(IUBMB) |
4-chlorophenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+ [RN: R03306]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
A system, containing a reductase and an iron-sulfur oxygenase, and no independent ferredoxin. Requires Fe2+. Also acts on 4-bromophenyl acetate.
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| History |
EC 1.14.12.9 created 1989 as EC 1.13.99.4, transferred 1992 to EC 1.14.12.9
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| Pathway |
| Tyrosine metabolism | | Microbial metabolism in diverse environments |
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| Reference |
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| Authors |
Markus A, Krekel D, Lingens F. |
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| Title |
Purification and some properties of component A of the 4-chlorophenylacetate 3,4-dioxygenase from Pseudomonas species strain CBS. |
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| Journal |
J. Biol. Chem. 261 (1986) 12883-8. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: UM-BBD (Biocatalysis/Biodegradation Database): BRENDA, the Enzyme Database: CAS: 105006-00-6 |
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| LinkDB |
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