| Entry |
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| Name |
mandelate 4-monooxygenase;
L-mandelate 4-hydroxylase;
mandelic acid 4-hydroxylase
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| Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
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| Sysname |
(S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
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| Reaction(IUBMB) |
(S)-2-hydroxy-2-phenylacetate + tetrahydrobiopterin + O2 = (S)-4-hydroxymandelate + dihydrobiopterin + H2O [RN: R03794]
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| Reaction(KEGG) |
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| Substrate |
(S)-2-hydroxy-2-phenylacetate [CPD: C01984];
tetrahydrobiopterin [CPD: C00272];
O2 [CPD: C00007]
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| Product |
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| Comment |
Requires Fe2+.
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| History |
EC 1.14.16.6 created 1984
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| Pathway |
| Aminobenzoate degradation | | Microbial metabolism in diverse environments |
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| Reference |
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| Authors |
Bhat SG, Vaidyanathan CS. |
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| Title |
Purifications and properties of L-mandelate- 4-hydroxylase from Pseudomonas convexa. |
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| Journal |
Arch. Biochem. Biophys. 176 (1976) 314-23. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 39459-82-0 |
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| LinkDB |
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