ENZYME: 1.3.1.30
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Entry
EC 1.3.1.30 Obsolete Enzyme
Name
Transferred to
1.3.1.30
and
1.3.1.22
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Comment
Transferred entry: EC
1.3.1.30
, progesterone 5alpha-reductase, transferred to EC
1.3.1.22
, 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+).
History
EC 1.3.1.30 created 1978, deleted 2012
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REACTION: R02208
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Entry
R02208 Reaction
Name
5alpha-pregnane-3,20-dione:NADP+ delta4-oxidoreductase
Definition
5alpha-Pregnane-3,20-dione + NADP+ <=> Progesterone + NADPH + H+
Equation
C03681
+
C00006
<=>
C00410
+
C00005
+
C00080
Reaction class
RC00001
C00005_C00006
RC00145
C00410_C03681
Enzyme
1.3.1.22
Pathway
rn00140
Steroid hormone biosynthesis
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22
R02208 5alpha-Pregnane-3,20-dione + NADP+ <=> Progesterone + NADPH + H+
IUBMB reaction hierarchy [BR:
br08202
]
1. Oxidoreductase reactions
1.3.1.22
R13214 3-Oxo-5alpha-steroid <=> 3-Oxo-Delta4-steroid
R02208 5alpha-Pregnane-3,20-dione <=> Progesterone
BRITE hierarchy
Orthology
K12343
3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:
1.3.1.22
]
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
K12345
3-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase [EC:
1.3.1.22
1.3.1.94
]
Other DBs
RHEA:
21955
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