Entry Name alkylacetylglycerophosphatase;
Class Hydrolases;BRITE hierarchy
Sysname 1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase
Reaction(IUBMB) 1-alkyl-2-acetyl-sn-glycero-3-phosphate + H2O = 1-alkyl-2-acetyl-sn-glycerol + phosphate [RN:
R03454 ]
Reaction(KEGG) Substrate 1-alkyl-2-acetyl-sn-glycero-3-phosphate [CPD:
C01264 ];
H2O [CPD:
C00001 ]
Product 1-alkyl-2-acetyl-sn-glycerol [CPD:
C03820 ];
phosphate [CPD:
C00009 ]
Comment Involved in the biosynthesis of thrombocyte activating factor in animal tissues.
History EC 3.1.3.59 created 1989
Pathway Reference Authors Lee TC, Malone B, Snyder F.
Title A new de novo pathway for the formation of 1-alkyl-2-acetyl-sn-glycerols, precursors of platelet activating factor. Biochemical characterization of 1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase in rat spleen.
Journal J Biol Chem 261:5373-7 (1986)
Other DBs ExplorEnz - The Enzyme Database: 3.1.3.59
ExPASy - ENZYME nomenclature database: 3.1.3.59
LinkDB All DBs
