KEGG   DRUG: NystatinHelp
Entry
D00202                      Drug                                   

Name
Nystatin (JP17/USP/INN);
NYS;
Mycostatin (TN)
Product
  Generic
NYSTATIN (A-S Medication Solutions), NYSTATIN (A-S Medication Solutions), NYSTATIN (A-S Medication Solutions), NYSTATIN (ATLANTIC BIOLOGICALS CORP.), NYSTATIN (ATLANTIC BIOLOGICALS CORP.), NYSTATIN (Actavis Mid Atlantic LLC), NYSTATIN (Actavis Mid Atlantic LLC), NYSTATIN (Aidarex Pharmaceuticals LLC), NYSTATIN (Aidarex Pharmaceuticals LLC), NYSTATIN (Arbor Pharmaceuticals), PEDIADERM AF (Arbor Pharmaceuticals), NYSTATIN (AvKARE), NYSTATIN (Avera McKennan Hospital), NYSTATIN (Bryant Ranch Prepack), NYSTATIN (Cardinal Health), NYSTATIN (Cardinal Health), NYSTATIN (Cardinal Health), NYSTATIN (Cardinal Health), NYSTATIN (Cardinal Health), NYSTATIN (Carilion Materials Management), NYSTATIN (Central Texas Community Health Centers), NYSTATIN (Dispensing Solutions), NYSTATIN (E. FOUGERA &), NYSTATIN (E. Fougera & Co. a division of Fougera Pharmaceuticals), NYSTATIN (E. Fougera & Co. a division of Fougera Pharmaceuticals), NYSTATIN (H.J. Harkins Company), NYSTATIN (Heritage Pharmaceuticals), NYSTATIN (Hi-Tech Pharmacal), NYSTATIN (Lake Erie Medical DBA Quality Care Products LLC), NYSTATIN (Lehigh Valley Technologies), NYSTATIN (Lupin Pharmaceuticals), NYSTATIN (Lyne Laboratories), NYSTATIN (Major Pharmaceuticals), NYSTATIN (Mayne Pharma), NYSTATIN (McKesson Packaging Services a business unit of McKesson Corporation), NYSTATIN (Morton Grove Pharmaceuticals), NYSTATIN (NuCare Pharmaceuticals), NYSTOP (Paddock Laboratories), NYSTATIN (Perrigo New York), NYSTATIN (Perrigo New York), NYSTATIN (Pharmaceutical Associates), NYSTATIN (Pharmaceutical Associates), NYSTATIN (Physicians Total Care), NYSTATIN (Physicians Total Care), NYSTATIN (Physicians Total Care), NYSTATIN (Physicians Total Care), NYSTATIN (Precision Dose), NYSTATIN (Preferred Pharmaceuticals), NYSTATIN (Preferred Pharmaceuticals), NYSTATIN (Preferred Pharmaceuticals), NYSTATIN (Preferred Pharmaceuticals), NYSTATIN (Preferred Pharmaceuticals), NYSTATIN (Preferred Pharmaceuticals), NYSTATIN (Proficient Rx LP), NYSTATIN (Proficient Rx LP), NYSTATIN (Proficient Rx LP), NYSTATIN (Qualitest Pharmaceuticals), NYSTATIN (Qualitest Pharmaceuticals), NYSTATIN (Rebel Distributors Corp), NYSTATIN (Rebel Distributors Corp), NYSTATIN (Rebel Distributors Corp), NYSTATIN (Rebel Distributors Corp), NYSTATIN (Rebel Distributors Corp), NYSTATIN (Rebel Distributors Corp), NYSTATIN (STAT Rx USA LLC), NYSTATIN (Sun Pharmaceutical Industries), NYSTATIN (Taro Pharmaceuticals U.S.A.), NYSTATIN (Taro Pharmaceuticals U.S.A.), NYSTATIN (Teva Pharmaceuticals USA), NYSTATIN (Unit Dose Services), NYAMYC (Upsher-Smith Laboratories), NYSTATIN (Vensun Pharmaceuticals), NYSTATIN (VistaPharm), NYSTATIN (VistaPharm), NYSTATIN (X-GEN Pharmaceuticals), NYSTATIN (Zydus Pharmaceuticals (USA)), NYSTATIN CREAM (Crown Laboratories), NYSTATIN (G&W Laboratories)
Formula
C47H75NO17
Exact mass
925.5035
Mol weight
926.0949
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Sequence
0 Mak  1 Mtk  2 Mtd  3 Mad  4 Mae  5 Mad  6 Mad  7 Mad  8 Mad
9 Mak  10 Mak  11 Mtk  12 Man  13 Mak  14 Mae  15 Mak  16 Mak
17 Mak  18 Man
  Type
PK
Source
Streptomyces noursei [TAX:1971]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Activity
Antibiotic, Antifungal
  Disease
Candidiasis [DS:H00363]
Comment
Natural product
Polyenes
Target
Ergosterol
Structure map
Antifungal agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA02 Nystatin
      D00202  Nystatin (JP17/USP/INN)
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AA Antibiotics
     D01AA01 Nystatin
      D00202  Nystatin (JP17/USP/INN)
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
   G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
    G01AA Antibiotics
     G01AA01 Nystatin
      D00202  Nystatin (JP17/USP/INN)
USP drug classification [BR:br08302]
 Antifungals
  Nystatin
   D00202  Nystatin (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   617  Acting mainly on mold
    6171  Nystatins
     D00202  Nystatin (JP17/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Nystatin
    D00202  Nystatin (JP17/USP/INN)
Antiinfectives [BR:br08307]
 Antifungals
  Cell membrane function inhibitor
   Polyene macrolides
    Nystatin
     D00202  Nystatin (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00202  Nystatin
Antifungals [br08352.html]
 D00202
BRITE hierarchy
Other DBs
CAS: 
1400-61-9
PubChem: 
ChEBI: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        65
            1   C1y C    34.7629  -15.2796
            2   O2a O    34.7629  -16.6820
            3   C1y C    33.5512  -14.5784
            4   O2x O    35.9745  -14.5784
            5   C1c C    33.5512  -17.3830
            6   C1y C    33.5443  -13.1762
            7   O1a O    32.3326  -15.2865
            8   C1y C    35.9745  -13.1762
            9   C1b C    33.5512  -18.7853
            10  C2b C    32.3871  -16.7090
            11  C1y C    34.7629  -12.4750
            12  N1a N    32.3326  -12.4819
            13  C1a C    37.1862  -12.4750
            14  C1c C    34.7696  -19.4863
            15  C2b C    31.1754  -17.4171
            16  O1a O    34.7629  -11.0728
            17  C1c C    34.7696  -20.8887
            18  O1a O    35.9813  -18.7853
            19  C2b C    29.9570  -16.7159
            20  C1c C    33.5579  -21.5899
            21  C6a C    35.9813  -21.5830
            22  C2b C    28.7453  -17.4171
            23  C1b C    32.3462  -20.8954
            24  O1a O    33.5648  -22.9854
            25  O6a O    35.9882  -22.9854
            26  O6a O    37.1999  -20.8818
            27  C2b C    27.5336  -16.7159
            28  C5a C    31.1414  -21.5966
            29  C2b C    26.3152  -17.4171
            30  C1b C    29.9297  -20.9024
            31  O5a O    31.1414  -22.9990
            32  C2b C    25.1035  -16.7226
            33  C1c C    28.7180  -21.6035
            34  C2b C    23.8918  -17.4238
            35  C1c C    27.5063  -20.9091
            36  O1a O    28.7180  -23.0057
            37  C1b C    22.6732  -16.7226
            38  C1b C    26.2947  -21.6103
            39  O1a O    27.5063  -19.5069
            40  C1b C    21.4615  -17.4238
            41  C1b C    25.0830  -20.9160
            42  C2b C    20.2500  -16.7226
            43  C1c C    23.8713  -21.6172
            44  C2b C    19.0314  -17.4307
            45  C1b C    22.6665  -20.9227
            46  O1a O    23.8782  -23.0194
            47  C2b C    17.8197  -16.7295
            48  C1c C    21.4548  -21.6239
            49  C2b C    16.6080  -17.4307
            50  C1b C    20.2431  -20.9296
            51  O1a O    21.4548  -23.0263
            52  C1c C    15.3896  -16.7295
            53  C1c C    19.0314  -21.6308
            54  C1c C    14.1780  -17.4374
            55  C1a C    15.3896  -15.3272
            56  C1b C    17.8197  -20.9363
            57  O1a O    19.0383  -23.0330
            58  C1c C    14.1780  -18.8329
            59  O1a O    12.9663  -16.7363
            60  C7a C    16.6080  -21.6375
            61  C1c C    15.3964  -19.5341
            62  C1a C    12.9663  -19.5408
            63  O7a O    15.3964  -20.9363
            64  O6a O    16.6150  -23.0397
            65  C1a C    16.6080  -18.8329
BOND        66
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 1 #Up
            7     4   8 1
            8     5   9 1
            9     5  10 1
            10    6  11 1
            11    6  12 1 #Up
            12    8  13 1 #Up
            13    9  14 1
            14   10  15 2
            15   11  16 1 #Down
            16   14  17 1
            17   14  18 1
            18   15  19 1
            19   17  20 1
            20   17  21 1
            21   19  22 2
            22   20  23 1
            23   20  24 1
            24   21  25 1
            25   21  26 2
            26   22  27 1
            27   23  28 1
            28   27  29 2
            29   28  30 1
            30   28  31 2
            31   29  32 1
            32   30  33 1
            33   32  34 2
            34   33  35 1
            35   33  36 1
            36   34  37 1
            37   35  38 1
            38   35  39 1
            39   37  40 1
            40   38  41 1
            41   40  42 1
            42   41  43 1
            43   42  44 2
            44   43  45 1
            45   43  46 1
            46   44  47 1
            47   45  48 1
            48   47  49 2
            49   48  50 1
            50   48  51 1
            51   49  52 1
            52   50  53 1
            53   52  54 1
            54   52  55 1
            55   53  56 1
            56   53  57 1
            57   54  58 1
            58   54  59 1
            59   56  60 1
            60   58  61 1
            61   58  62 1
            62   60  63 1
            63   60  64 2
            64   61  65 1
            65    8  11 1
            66   61  63 1

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