KEGG   DRUG: AcetaminophenHelp
Entry
D00217                      Drug                                   

Name
Acetaminophen (JP17/USP);
Paracetamol (INN);
Tylenol (TN)
Product
  Generic
  Other
Formula
C8H9NO2
Exact mass
151.0633
Mol weight
151.1626
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01981  Antiinflammatory drug, anilide derivatives
Cyp substrate
 DG01892  CYP1A2 substrate
 DG01638  CYP2A6 substrate
 DG01633  CYP3A substrate
Remark
Same as: C06804
Therapeutic category: 1141
ATC code: N02BE01
Product: D00217<JP/US>
Product (mixture): D04046<JP> D02153<US> D00846<US> D04044<JP> D08695<JP> D03976<JP> D09999<JP/US> D02146<US>
Efficacy
Analgesic, Antipyretic
Comment
Aniline derivative, Anilide derivative
Interaction
Drug interaction
Structure map
map07048  Antimigraines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02B OTHER ANALGESICS AND ANTIPYRETICS
    N02BE Anilides
     N02BE01 Paracetamol
      D00217  Acetaminophen (JP17/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   114  Antipyretics and analgesics, anti-inflammatory agents
    1141  Anilines
     D00217  Acetaminophen (JP17/USP); Paracetamol (INN)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for nervous and sensory systems
  01 Cold remedy (oral use)
   D00217  Acetaminophen (JP17/USP)
  03 Antipyretic analgesic agents
   D00217  Acetaminophen (JP17/USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Acetaminophen
    D00217  Acetaminophen (JP17/USP)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   cyclooxygenase-1 (COX-1)
    Acetaminophen
     D00217  Acetaminophen (JP17/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00217  Acetaminophen
Drug classes of therapeutic agents [br08360.html]
 Anesthetics, analgesics and anti-inflammatory drugs
  D00217
Rx-to-OTC switch list in the USA [br08315.html]
 D00217
Prodrugs [br08324.html]
 D00217
BRITE hierarchy
Other DBs
CAS: 103-90-2
PubChem: 7847284
ChEBI: 46195
ChEMBL: CHEMBL112
DrugBank: DB00316
PDB-CCD: TYL[PDBj]
LigandBox: D00217
NIKKAJI: J4.025H
LinkDB All DBs
KCF data Show

ATOM        11
            1   C8y C    21.1806  -16.6437
            2   C8x C    21.1806  -18.0466
            3   C8x C    19.9699  -15.9511
            4   N1b N    22.3914  -15.9511
            5   C8x C    19.9699  -18.7509
            6   C8x C    18.7534  -16.6437
            7   C5a C    23.6080  -16.6496
            8   C8y C    18.7534  -18.0466
            9   C1a C    24.8186  -15.9511
            10  O5a O    23.6020  -18.0466
            11  O1a O    17.5425  -18.7509
BOND        11
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     7   9 1
            9     7  10 2
            10    8  11 1
            11    6   8 2

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