| Entry |
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| Name |
Terazosin hydrochloride (USAN);
Terazosin hydrochloride hydrate (JAN);
Hytrin (TN)
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| Product |
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| Generic |
TERAZOSIN (A-S Medication Solutions), TERAZOSIN (Aidarex Pharmaceuticals LLC), TERAZOSIN (Apotex Corp.), TERAZOSIN (Blenheim Pharmacal), TERAZOSIN HYDROCHLORIDE (NCS HealthCare of KY), TERAZOSIN (NCS HealthCare of KY), TERAZOSIN (Preferred Pharmaceuticals), TERAZOSIN (A-S Medication Solutions), TERAZOSIN HYDROCHLORIDE (A-S Medication Solutions), TERAZOSIN (A-S Medication Solutions), TERAZOSIN HYDROCHLORIDE (A-S Medication Solutions), TERAZOSIN (A-S Medication Solutions), TERAZOSIN (A-S Medication Solutions), TERAZOSIN (Aidarex Pharmaceuticals LLC), TERAZOSIN HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), TERAZOSIN HYDROCHLORIDE (Bryant Ranch Prepack), TERAZOSIN (Bryant Ranch Prepack), TERAZOSIN HYDROCHLORIDE (Bryant Ranch Prepack), TERAZOSIN HYDROCHLORIDE (Cardinal Health), TERAZOSIN (Clinical Solutions Wholesale), TERAZOSIN (Jubilant Cadista Pharmaceuticals), TERAZOSIN HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), TERAZOSIN HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), TERAZOSIN HYDROCHLORIDE (Major Pharmaceuticals), TERAZOSIN (Northwind Pharmaceuticals), TERAZOSIN (Northwind Pharmaceuticals), TERAZOSIN (NuCare Pharmaceuticals), TERAZOSIN (NuCare Pharmaceuticals), TERAZOSIN HYDROCHLORIDE (Physicians Total Care), TERAZOSIN HYDROCHLORIDE (Preferred Pharmaceuticals), TERAZOSIN (Proficient Rx LP), TERAZOSIN (Proficient Rx LP), TERAZOSIN (REMEDYREPACK), TERAZOSIN (REMEDYREPACK), TERAZOSIN HYDROCHLORIDE (REMEDYREPACK), TERAZOSIN (REMEDYREPACK), TERAZOSIN HYDROCHLORIDE (Rebel Distributors Corp), TERAZOSIN HYDROCHLORIDE (STAT Rx USA LLC), TERAZOSIN HYDROCHLORIDE (Sandoz), TERAZOSIN (State of Florida DOH Central Pharmacy), TERAZOSIN HYDROCHLORIDE (State of Florida DOH Central Pharmacy), TERAZOSIN HYDROCHLORIDE (State of Florida DOH Central Pharmacy), TERAZOSIN HYDROCHLORIDE (State of Florida DOH Central Pharmacy), TERAZOSIN HYDROCHLORIDE (Unit Dose Services) |
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| Formula |
C19H25N5O4. 2H2O. HCl
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| Exact mass |
459.1885
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| Mol weight |
459.9244
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| Structure |
     |
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| Simcomp |
 |
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| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
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| Remark |
Therapeutic category: ATC code: Chemical group: |
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| Activity |
Antidysuria, Antihypertensive, alpha1-Adrenergic receptor antagonist |
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| Comment |
Prazosin derivative
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| Target |
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| Pathway |
| Calcium signaling pathway | | Neuroactive ligand-receptor interaction | | Vascular smooth muscle contraction | | Salivary secretion |
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| Interaction |
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| Structure map |
| alpha-Adrenergic receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G04 UROLOGICALS
G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
G04CA Alpha-adrenoreceptor antagonists
G04CA03 Terazosin
D00610 Terazosin hydrochloride (USAN)
USP drug classification [BR:br08302]
Cardiovascular Agents
Alpha-adrenergic Blocking Agents
Terazosin
D00610 Terazosin hydrochloride (USAN)
Genitourinary Agents
Benign Prostatic Hypertrophy Agents
Terazosin
D00610 Terazosin hydrochloride (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
214 Antihypertensives
2149 Others
D00610 Terazosin hydrochloride (USAN); Terazosin hydrochloride hydrate (JAN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
alpha1-adrenergic receptor
Terazosin
D00610 Terazosin hydrochloride (USAN)
Cardiovascular agents [br08364.html]
Antihypertensives
D00610
Endocrine and hormonal agents [br08373.html]
Other urological agents
D00610
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| Other DBs |
CAS: 70024-40-7 PubChem: ChEBI: DrugBank: LigandBox: |
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| LinkDB |
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| KCF data |
ATOM 31
1 C8y C 31.5616 -18.9123
2 C8y C 31.5616 -17.5048
3 C8x C 32.7916 -19.6220
4 C8y C 30.3553 -19.6220
5 N5x N 30.3553 -16.8247
6 C8x C 32.7916 -16.8247
7 C8y C 33.9921 -18.9123
8 N5x N 29.1488 -18.9123
9 N1a N 30.3553 -21.0235
10 C8y C 29.1488 -17.5048
11 C8y C 33.9921 -17.5048
12 O2a O 35.2223 -19.6220
13 N1y N 27.9365 -16.8247
14 O2a O 35.2223 -16.8247
15 C1a C 36.4286 -18.9063
16 C1x C 27.9365 -15.4290
17 C1x C 26.7184 -17.5048
18 C1a C 36.4286 -17.5167
19 C1x C 26.7184 -14.7195
20 C1x C 25.5119 -16.8247
21 N1y N 25.5119 -15.4290
22 C5a C 24.2600 -14.7132
23 C1y C 23.0787 -15.4020
24 O5a O 24.3238 -13.3005
25 C1x C 23.0787 -16.8020
26 O2x O 21.7472 -14.9694
27 C1x C 20.9243 -16.1020
28 C1x C 21.7472 -17.2346
29 O0 O 41.8575 -18.0785
30 X Cl 41.1600 -15.7500
31 O0 O 41.8575 -18.0785
BOND 31
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 4 9 1
9 5 10 2
10 6 11 2
11 7 12 1
12 10 13 1
13 11 14 1
14 12 15 1
15 13 16 1
16 13 17 1
17 14 18 1
18 16 19 1
19 17 20 1
20 19 21 1
21 7 11 1
22 8 10 1
23 20 21 1
24 21 22 1
25 22 23 1
26 22 24 2
27 23 25 1
28 23 26 1
29 26 27 1
30 27 28 1
31 25 28 1
BRACKET 1 39.5500 -19.0400 39.5500 -17.3600
1 42.6300 -17.3600 42.6300 -19.0400
1 2
ORIGINAL 1 29
REPEAT 1 31
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