| Entry |
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| Name |
Chlorzoxazone (JAN/USP/INN);
Paraflex (TN)
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| Product |
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| Generic |
CHLORZOXAZONE (A-S Medication Solutions), CHLORZOXAZONE (A-S Medication Solutions), CHLORZOXAZONE (A-S Medication Solutions), CHLORZOXAZONE (Actavis Pharma), CHLORZOXAZONE (Aidarex Pharmaceuticals LLC), CHLORZOXAZONE (Bryant Ranch Prepack), CHLORZOXAZONE (Clinical Solutions Wholesale), CHLORZOXAZONE (DIRECT RX), CHLORZOXAZONE (Dispensing Solutions), CHLORZOXAZONE (Dispensing Solutions), PARAFON DSC (Keltman Pharmaceuticals), LORZONE (Lake Erie Medical DBA Quality Care Products LLC), CHLORZOXAZONE (Lake Erie Medical DBA Quality Care Products LLC), CHLORZOXAZONE (Mikart), CHLORZOXAZONE (Mikart), CHLORZOXAZONE (NuCare Pharmaceuticals), CHLORZOXAZONE (PD-Rx Pharmaceuticals), CHLORZOXAZONE (Physicians Total Care), CHLORZOXAZONE (Proficient Rx LP), CHLORZOXAZONE (Rebel Distributors Corp), CHLORZOXAZONE (Rebel Distributors Corp), CHLORZOXAZONE (STAT Rx USA LLC), CHLORZOXAZONE (Unit Dose Services), LORZONE (Vertical Pharmaceuticals) |
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| Formula |
C7H4ClNO2
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| Exact mass |
168.9931
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| Mol weight |
169.5652
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| Structure |
     |
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| Simcomp |
 |
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| Class |
Other
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
DG01974 Centrally acting muscle relaxant
Cyp substrate
DG01892 CYP1A2 substrate
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| Remark |
Same as: Therapeutic category: ATC code: |
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| Activity |
Skeletal muscle relaxant |
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| Comment |
Benzoxazole derivative
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| Metabolism |
Enzyme: CYP1A2 [HSA: 1544], CYP2E1 [HSA: 1571]
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M03 MUSCLE RELAXANTS
M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS
M03BB Oxazol, thiazine, and triazine derivatives
M03BB03 Chlorzoxazone
D00771 Chlorzoxazone (JAN/USP/INN)
USP drug classification [BR:br08302]
Skeletal Muscle Relaxants
Chlorzoxazone
D00771 Chlorzoxazone (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
122 Skeletal muscle relaxants
1222 Chlorzoxazons
D00771 Chlorzoxazone (JAN/USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for nervous and sensory systems
08 Other drugs for nervous and sensory organs
D00771 Chlorzoxazone (JAN/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Chlorzoxazone
D00771 Chlorzoxazone (JAN/USP/INN)
Cytochrome P450 interactions [BR:br08309]
CYP inhbitors
CYP3A
Chlorzoxazone
D00771 Chlorzoxazone (JAN/USP/INN)
CYP substrates
CYP1A2
Chlorzoxazone
D00771 Chlorzoxazone (JAN/USP/INN)
 |
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| Other DBs |
CAS: 95-25-0 PubChem: ChEBI: ChEMBL: DrugBank: PDB-CCD: LigandBox: NIKKAJI: |
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| LinkDB |
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| KCF data |
ATOM 11
1 C8y C 21.0882 -14.4991
2 C8y C 21.0823 -15.9033
3 O2x O 22.4280 -14.0720
4 C8x C 19.8829 -13.8029
5 N5x N 22.4162 -16.3423
6 C8x C 19.8829 -16.5997
7 C8y C 23.2471 -15.2129
8 C8x C 18.6660 -14.4991
9 C8y C 18.6660 -15.8976
10 O1a O 24.6396 -15.2072
11 X Cl 17.4491 -16.5937
BOND 12
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 4 8 2
8 6 9 2
9 7 10 1
10 9 11 1
11 5 7 2
12 8 9 1
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