KEGG   DRUG: ChlorzoxazoneHelp
Entry
D00771                      Drug                                   

Name
Chlorzoxazone (JAN/USP/INN);
Paraflex (TN)
Product
  Generic
CHLORZOXAZONE (A-S Medication Solutions), CHLORZOXAZONE (A-S Medication Solutions), CHLORZOXAZONE (A-S Medication Solutions), CHLORZOXAZONE (Actavis Pharma), CHLORZOXAZONE (Aidarex Pharmaceuticals LLC), CHLORZOXAZONE (Bryant Ranch Prepack), CHLORZOXAZONE (Clinical Solutions Wholesale), CHLORZOXAZONE (DIRECT RX), CHLORZOXAZONE (Dispensing Solutions), CHLORZOXAZONE (Dispensing Solutions), PARAFON DSC (Keltman Pharmaceuticals), LORZONE (Lake Erie Medical DBA Quality Care Products LLC), CHLORZOXAZONE (Lake Erie Medical DBA Quality Care Products LLC), CHLORZOXAZONE (Mikart), CHLORZOXAZONE (Mikart), CHLORZOXAZONE (NuCare Pharmaceuticals), CHLORZOXAZONE (PD-Rx Pharmaceuticals), CHLORZOXAZONE (Physicians Total Care), CHLORZOXAZONE (Proficient Rx LP), CHLORZOXAZONE (Rebel Distributors Corp), CHLORZOXAZONE (Rebel Distributors Corp), CHLORZOXAZONE (STAT Rx USA LLC), CHLORZOXAZONE (Unit Dose Services), LORZONE (Vertical Pharmaceuticals)
Formula
C7H4ClNO2
Exact mass
168.9931
Mol weight
169.5652
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Other
 DG02029  Muscle relaxant
  DG01974  Centrally acting muscle relaxant
 DG01974  Centrally acting muscle relaxant
Cyp substrate
 DG01892  CYP1A2 substrate
Remark
Same as: 
Therapeutic category: 
ATC code: 
Activity
Skeletal muscle relaxant
Comment
Benzoxazole derivative
Metabolism
Enzyme: CYP1A2 [HSA:1544], CYP2E1 [HSA:1571]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M03 MUSCLE RELAXANTS
   M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS
    M03BB Oxazol, thiazine, and triazine derivatives
     M03BB03 Chlorzoxazone
      D00771  Chlorzoxazone (JAN/USP/INN)
USP drug classification [BR:br08302]
 Skeletal Muscle Relaxants
  Chlorzoxazone
   D00771  Chlorzoxazone (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   122  Skeletal muscle relaxants
    1222  Chlorzoxazons
     D00771  Chlorzoxazone (JAN/USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for nervous and sensory systems
  08 Other drugs for nervous and sensory organs
   D00771  Chlorzoxazone (JAN/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Chlorzoxazone
    D00771  Chlorzoxazone (JAN/USP/INN)
Cytochrome P450 interactions [BR:br08309]
 CYP inhbitors
  CYP3A
   Chlorzoxazone
    D00771  Chlorzoxazone (JAN/USP/INN)
 CYP substrates
  CYP1A2
   Chlorzoxazone
    D00771  Chlorzoxazone (JAN/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
95-25-0
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        11
            1   C8y C    21.0882  -14.4991
            2   C8y C    21.0823  -15.9033
            3   O2x O    22.4280  -14.0720
            4   C8x C    19.8829  -13.8029
            5   N5x N    22.4162  -16.3423
            6   C8x C    19.8829  -16.5997
            7   C8y C    23.2471  -15.2129
            8   C8x C    18.6660  -14.4991
            9   C8y C    18.6660  -15.8976
            10  O1a O    24.6396  -15.2072
            11  X   Cl   17.4491  -16.5937
BOND        12
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 2
            8     6   9 2
            9     7  10 1
            10    9  11 1
            11    5   7 2
            12    8   9 1

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