KEGG   DRUG: Cyclobenzaprine hydrochlorideHelp
Entry
D00772                      Drug                                   

Name
Cyclobenzaprine hydrochloride (USP);
Flexeril (TN)
Product
  Generic
CYCLOBENZAPRINE HYDROCHLORIDE (Cipla USA), CYCLOBENZAPRINE HYDROCHLORIDE (Coupler Enterprises), CYCLOBENZAPRINE (DIRECT RX), CYCLOTENS STARTER PAK (Hudson Scientific LLC), CYCLOTENS REFILL PAK (Hudson Scientific LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Hudson Scientific LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Legacy Pharmaceutical Packaging), CYCLOBENZAPRINE HYDROCHLORIDE (NCS HealthCare of KY), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Preferred Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Proficient Rx LP), CYCLOBENZAPRINE HYDROCHLORIDE (REMEDYREPACK), CYCLOBENZAPRINE HYDROCHLORIDE (REMEDYREPACK), CYCLOBENZAPRINE HYDROCHLORIDE (REMEDYREPACK), CYCLOBENZAPRINE HYDROCHLORIDE (RPK Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Unit Dose Services), CYCLOBENZAPRINE HYDROCHLORIDE (Virtue Rx), CYCLOBENZAPRINE HCL (Oxford Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (1 Veterans Health), CYCLOBENZAPRINE HYDROCHLORIDE (A-S Medication Solutions), CYCLOBENZAPRINE HYDROCHLORIDE (Actavis Pharma), CYCLOBENZAPRINE HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), CYCLOBENZAPRINE HYDROCHLORIDE (All Pharma), CYCLOBENZAPRINE HYDROCHLORIDE (American Health Packaging), CYCLOBENZAPRINE HYDROCHLORIDE (Amneal Pharmaceuticals LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Amneal Pharmaceuticals of New York LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), CYCLOBENZAPRINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), CYCLOBENZAPRINE HYDROCHLORIDE (Apotheca), CYCLOBENZAPRINE HYDROCHLORIDE (Aurobindo Pharma Limited), CYCLOBENZAPRINE HYDROCHLORIDE (AvPAK), CYCLOBENZAPRINE HYDROCHLORIDE (Blenheim Pharmacal), CYCLOBENZAPRINE HYDROCHLORIDE (Blenheim Pharmacal), CYCLOBENZAPRINE HYDROCHLORIDE (Blenheim Pharmacal), CYCLOBENZAPRINE HYDROCHLORIDE (Bryant Ranch Prepack), CYCLOBENZAPRINE HYDROCHLORIDE (Bryant Ranch Prepack), CYCLOBENZAPRINE HYDROCHLORIDE (Bryant Ranch Prepack), CYCLOBENZAPRINE HYDROCHLORIDE (Bryant Ranch Prepack), CYCLOBENZAPRINE HYROCHLORIDE (Bryant Ranch Prepack), CYCLOBENZAPRINE HYDROCHLORIDE (Bryant Ranch Prepack), CYCLOBENZAPRINE HYDROCHLORIDE (Bryant Ranch Prepack), CYCLOBENZAPRINE HYDROCHLORIDE (Camber Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Cardinal Health), CYCLOBENZAPRINE HYDROCHLORIDE (Citron Pharma LLC), CYCLOBENZAPRINE (Citron Pharma LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Clinical Solutions Wholesale), CYCLOBENZAPRINE HYDROCHLORIDE (Contract Pharmacy Services-PA), CYCLOBENZAPRINE HYDROCHLORIDE (Contract Pharmacy Services-PA), CYCLOBENZAPRINE HYDROCHLORIDE (Contract Pharmacy Services-PA), CYCLOBENZAPRINE HYDROCHLORIDE (DIRECT RX), CYCLOBENZAPRINE HYDROCHLORIDE (DIRECT RX), CYCLOBENZAPRINE HYDROCHLORIDE (DIRECT RX), CYCLOBENZAPRINE HYDROCHLORIDE (DIRECT RX), CYCLOBENZAPRINE HYDROCHLORIDE (Denton Pharma), CYCLOBENZAPRINE HYDROCHLORIDE (Direct Rx), CYCLOBENZAPRINE HYDROCHLORIDE (Dispensing Solutions), CYCLOBENZAPRINE HYDROCHLORIDE (Dispensing Solutions), CYCLOBENZAPRINE HYDROCHLORIDE (Dispensing Solutions), CYCLOBENZAPRINE HYDROCHLORIDE (Golden State Medical Supply), CYCLOBENZAPRINE HYDROCHLORIDE (Golden State Medical Supply), CYCLOBENZAPRINE HYDROCHLORIDE (H. J Harkins Company), CYCLOBENZAPRINE HYDROCHLORIDE (H. J. Harkins Company), CYCLOBENZAPRINE HYROCHLORIDE (H.J. Harkins Company), CYCLOBENZAPRINE HYDROCHLORIDE (IPG PHARMACEUTICALS), CYCLOBENZAPRINE HYDROCHLORIDE (Innovida Pharmaceutique Corporation), CYCLOBENZAPRINE HYDROCHLORIDE (Jubilant Cadista Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (KAISER FOUNDATION HOSPITALS), CYCLOBENZAPRINE HYDROCHLORIDE (KAISER FOUNDATION HOSPITALS), CYCLOBENZAPRINE HYDROCHLORIDE (KVK-TECH), CYCLOBENZAPRINE HYDROCHLORIDE (Keltman Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Product LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CYCLOBENZAPRINE HYROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), FEXMID (Lake Erie Medical DBA Quality Care Products LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CYCLOBENZAPRINE HYDROCHLORIDE (Legacy Pharmaceutical Packaging), CYCLOBENZAPRINE HYDROCHLORIDE (Liberty Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Liberty Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Major Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (McKesson Corporation), CYCLOBENZAPRINE HYDROCHLORIDE (MedVantx), CYCLOBENZAPRINE HYDROCHLORIDE (Medsource Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Medsource Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Mutual Pharmaceutical), CYCLOBENZAPRINE HYDROCHLORIDE (Mylan Institutional), CYCLOBENZAPRINE HYDROCHLORIDE (Mylan Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NCS HealthCare of KY), CYCLOBENZAPRINE HYDROCHLORIDE (New Horizon Rx Group), CYCLOBENZAPRINE HYDROCHLORIDE (Northwind Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Northwind Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Northwind Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (NuCare Pharmaceuticals), COMFORT PAC WITH CYCLOBENZAPRINE (PD-Rx Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Physicians Total Care), CYCLOBENZAPRINE HYDROCHLORIDE (Preferred Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Preferred Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Preferred Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Preferred Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Preferred Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Preferred Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Proficient Rx LP), CYCLOBENZAPRINE HYDROCHLORIDE (Proficient Rx LP), CYCLOBENZAPRINE HYDROCHLORIDE (Proficient Rx LP), CYCLOBENZAPRINE HYDROCHLORIDE (Proficient Rx LP), CYCLOBENZAPRINE HYDROCHLORIDE (Proficient Rx LP), CYCLOBENZAPRINE HYDROCHLORIDE (Proficient Rx LP), CYCLOBENZAPRINE HYDROCHLORIDE (Proficient Rx LP), CYCLOBENZAPRINE HYDROCHLORIDE (Proficient Rx LP), CYCLOBENZAPRINE HYDROCHLORIDE (QPharma), CYCLOBENZAPRINE HYDROCHLORIDE (Qualitest Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (REMEDYREPACK), CYCLOBENZAPRINE HYDROCHLORIDE (REMEDYREPACK), CYCLOBENZAPRINE HYDROCHLORIDE (REMEDYREPACK), CYCLOBENZAPRINE HYDROCHLORIDE (REMEDYREPACK), CYCLOBENZAPRINE HYDROCHLORIDE (REMEDYREPACK), CYCLOBENZAPRINE HYDROCHLORIDE (REMEDYREPACK), CYCLOBENZAPRINE HYDROCHLORIDE (REMEDYREPACK), CYCLOBENZAPRINE HYDROCHLORIDE (RPK Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (Ranbaxy Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (ReadyMeds), CYCLOBENZAPRINE HYDROCHLORIDE (Rebel Distributors), CYCLOBENZAPRINE HYDROCHLORIDE (Rebel Distributors), CYCLOBENZAPRINE HYROCHLORIDE (Rebel Distributors Corp), FEXMID (Rebel Distributors Corp), CYCLOBENZAPRINE HYDROCHLORIDE (RedPharm Drug), CYCLOBENZAPRINE HYDROCHLORIDE (RedPharm Drug), CYCLOBENZAPRINE HYDROCHLORIDE (RedPharm Drug), CYCLOBENZAPRINE HYDROCHLORIDE (RedPharm Drug), CYCLOBENZAPRINE HYDROCHLORIDE (RedPharm Drug), CYCLOBENZAPRINE HYDROCHLORIDE (RedPharm Drug), CYCLOBENZAPRINE HYDROCHLORIDE (RedPharm Drug), CYCLOBENZAPRINE HYDROCHLORIDE (RedPharm Drug), CYCLOBENZAPRINE HYDROCHLORIDE (RedPharm Drug), CYCLOBENZAPRINE HYDROCHLORIDE (RxChange), CYCLOBENZAPRINE HYDROCHLORIDE (SA3), FEXMID (Shionogi), CYCLOBENZAPRINE HYDROCHLORIDE (Solco Healthcare U.S.), CYCLOBENZAPRINE HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), CYCLOBENZAPRINE HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), CYCLOBENZAPRINE HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), CYCLOBENZAPRINE HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), CYCLOBENZAPRINE HYDROCHLORIDE (State of Florida DOH Central Pharmacy), CYCLOBENZAPRINE HYDROCHLORIDE (State of Florida DOH Central Pharmacy), CYCLOBENZAPRINE HYDROCHLORIDE (State of Florida DOH Central Pharmacy), CYCLOBENZAPRINE HYDROCHLORIDE (State of Florida DOH Central Pharmacy), CYCLOBENZAPRINE HYDROCHLORIDE (Sterling Knight Pharmaceuticals), CYCLOBENZAPRINE HYDROCHLORIDE (TMIG), CYCLOBENZAPRINE HYDROCHLORIDE (TruPharma LLC), CYCLOBENZAPRINE HYDROCHLORIDE (TruPharma), CYCLOBENZAPRINE HYDROCHLORIDE (Unit Dose Services), CYCLOBENZAPRINE HYDROCHLORIDE (Unit Dose Services), FEXMID (Unit Dose Services), CYCLOBENZAPRINE HYDROCHLORIDE (Unit Dose Services)
  Other
Formula
C20H21N. HCl
Exact mass
311.1441
Mol weight
311.8484
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Other
 DG02029  Muscle relaxant
  DG01974  Centrally acting muscle relaxant
 DG01974  Centrally acting muscle relaxant
Cyp substrate
 DG01892  CYP1A2 substrate
Remark
ATC code: M03BX08
Chemical structure group: DG00775
Product (DG00775): D00772<US>
Efficacy
Muscle relaxant
Comment
Tricyclic compounds
Metabolism
Enzyme: CYP1A2 [HSA:1544]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M03 MUSCLE RELAXANTS
   M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS
    M03BX Other centrally acting agents
     M03BX08 Cyclobenzaprine
      D00772  Cyclobenzaprine hydrochloride (USP) <US>
USP drug classification [BR:br08302]
 Skeletal Muscle Relaxants
  Cyclobenzaprine
   D00772  Cyclobenzaprine hydrochloride (USP)
BRITE hierarchy
Other DBs
CAS: 6202-23-9
PubChem: 7847837
ChEBI: 3997
ChEMBL: CHEMBL1200636
DrugBank: DB00924
LigandBox: D00772
NIKKAJI: J220.308A
LinkDB All DBs
KCF data Show

ATOM        22
            1   C2x C    17.2008  -18.3231
            2   C8y C    16.3561  -17.2101
            3   C8y C    16.6923  -15.8492
            4   C2y C    17.9572  -15.2693
            5   C2x C    18.6109  -18.3484
            6   C8y C    19.2146  -15.8935
            7   C8y C    19.5020  -17.2664
            8   C8x C    15.6821  -14.8778
            9   C8x C    14.3360  -15.2671
            10  C8x C    13.9998  -16.6280
            11  C8x C    15.0100  -17.5991
            12  C8x C    20.8372  -17.7048
            13  C8x C    21.8846  -16.7676
            14  C8x C    21.5974  -15.3947
            15  C8x C    20.2619  -14.9562
            16  C2b C    17.9789  -13.8902
            17  C1b C    19.2067  -13.2070
            18  C1b C    20.3786  -13.9086
            19  N1c N    21.6045  -13.2265
            20  C1a C    22.8430  -13.9673
            21  C1a C    21.6266  -11.8540
            22  X   Cl   24.8607  -16.4881
BOND        23
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17    6  15 2
            18    4  16 2
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   19  21 1

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