KEGG   DRUG: Ketorolac tromethamineHelp
Entry
D00813                      Drug                                   

Name
Ketorolac tromethamine (USP);
Acular (TN);
Toradol (TN)
Product
  Generic
KETOROLAC TROMETHAMINE (AGILA SPECIALTIES PRIVATE LIMITED), KETOROLAC TROMETHAMINE (Aidarex Pharmaceuticals LLC), KETOROLAC TROMETHAMINE (Akorn), KETOROLAC TROMETHAMINE (Akorn), KETOROLAC TROMETHAMINE (Akorn), KETOROLAC TROMETHAMINE (American Regent), KETOROLAC TROMETHAMINE (Amphastar Pharmaceuticals), KETOROLAC TROMETHAMINE (Apotex Corp.), KETOROLAC TROMETHAMINE (Apotheca), KETOROLAC TROMETHAMINE (Athenex Pharmaceutical Division), KETOROLAC TROMETHAMINE (AvKARE), KETOROLAC TROMETHAMINE (Avera McKennan Hospital), KETOROLAC TROMETHAMINE (Blenheim Pharmacal), KETOROLAC TROMETHAMINE (Bryant Ranch Prepack), KETOROLAC TROMETHAMINE (Cardinal Health), KETOROLAC TROMETHAMINE (Cardinal Health), KETOROLAC TROMETHAMINE (Cardinal Health), KETOROLAC TROMETHAMINE (Cardinal Health), KETOROLAC TROMETHAMINE (Cardinal Health), KETOROLAC TROMETHAMINE (Cardinal Health), KETOROLAC TROMETHAMINE (Cardinal Health), KETOROLAC TROMETHAMINE (Cardinal Health), KETOROLAC TROMETHAMINE (Carilion Materials Management), KETOROLAC TROMETHAMINE (Central Texas Community Health Centers), KETOROLAC TROMETHAMINE (DIRECT RX), KETOROLAC TROMETHAMINE (Denton Pharma), KETOROLAC TROMETHAMINE (Falcon Pharmaceuticals), KETOROLAC TROMETHAMINE (Fresenius Kabi USA), KETOROLAC TROMETHAMINE (Fresenius Kabi USA), KETOROLAC TROMETHAMINE (Fresenius Kabi USA), KETOROLAC TROMETHAMINE (Fresenius Kabi USA), KETOROLAC TROMETHAMINE (General Injectables & Vaccines), KETOROLAC TROMETHAMINE (General Injectables & Vaccines), KETOROLAC TROMETHAMINE (Gland Pharma Limited), KETOROLAC TROMETHAMINE (Gland Pharma Limited), KETOROLAC TROMETHAMINE (H.J. Harkins Company), KETOROLAC TROMETHAMINE (Hospira), KETOROLAC TROMETHAMINE (Hospira), KETOROLAC TROMETHAMINE (Hospira), KETOROLAC TROMETHAMINE (Keltman Pharmaceuticals), KETOROLAC TROMETHAMINE (Lake Erie Medical DBA Quality Care Products LLC), KETOROLAC TROMETHAMINE (Lake Erie Medical DBA Quality Care Products LLC), KETOROLAC TROMETHAMINE (Lake Erie Medical DBA Quality Care Products LLC), KETOROLAC TROMETHAMINE (Mylan Pharmaceuticals), KETOROLAC TROMETHAMINE (Northwind Pharmaceuticals), KETOROLAC TROMETHAMINE (NuCare Pharmaceuticals), KETOROLAC TROMETHAMINE (NuCare Pharmaceuticals), KETOROLAC TROMETHAMINE (NuCare Pharmaceuticals), KETOROLAC TROMETHAMINE (NuCare Pharmaceuticals), KETOROLAC TROMETHAMINE (PD-Rx Pharmaceuticals), KETOROLAC TROMETHAMINE (PD-Rx Pharmaceuticals), KETOROLAC TROMETHAMINE (Pacific Pharma), KETOROLAC TROMETHAMINE (Physicians Total Care), KETOROLAC TROMETHAMINE (Physicians Total Care), KETOROLAC TROMETHAMINE (Physicians Total Care), KETOROLAC TROMETHAMINE (Physicians Total Care), KETOROLAC TROMETHAMINE (Preferred Pharmaceuticals), KETOROLAC TROMETHAMINE (Preferred Pharmaceuticals), KETOROLAC TROMETHAMINE (Preferred Pharmaceuticals), KETOROLAC TROMETHAMINE (Preferred Pharmaceuticals), KETOROLAC TROMETHAMINE (Proficient Rx LP), KETOROLAC TROMETHAMINE (Proficient Rx LP), KETOROLAC TROMETHAMINE (Proficient Rx LP), KETOROLAC TROMETHAMINE (REMEDYREPACK), KETOROLAC TROMETHAMINE (REMEDYREPACK), KETOROLAC TROMETHAMINE (REMEDYREPACK), KETOROLAC TROMETHAMINE (REMEDYREPACK), KETOROLAC TROMETHAMINE (REMEDYREPACK), KETOROLAC TROMETHAMINE (REMEDYREPACK), KETOROLAC TROMETHAMINE (REMEDYREPACK), KETOROLAC TROMETHAMINE (ReadyMeds), KETOROLAC TROMETHAMINE (Rebel Distributors Corp), KETOROLAC TROMETHAMINE (Rebel Distributors Corp), KETOROLAC TROMETHAMINE (Rebel Distributors Corp), KETOROLAC TROMETHAMINE (Rebel Distributors Corp), KETOROLAC TROMETHAMINE (RedPharm Drug), KETOROLAC TROMETHAMINE (STAT RX USA LLC), KETOROLAC (STAT RX USA LLC), KETOROLAC TROMETHAMINE (Sagent Pharmaceuticals), KETOROLAC TROMETHAMINE (Sandoz), READYSHARP KETOROLAC (Terrain Pharmaceuticals), KETOROLAC TROMETHAMINE (Teva Pharmaceuticals USA), KETOROLAC TROMETHAMINE (Unit Dose Services), KETOROLAC TROMETHAMINE (Unit Dose Services), KETOROLAC TROMETHAMINE (WOCKHARDT LIMITED), KETOROLAC TROMETHAMINE (WOCKHARDT USA LLC), KETOROLAC TROMETHAMINE (West-ward Pharmaceutical Corp.), KETOTOLAC TROMETHAMINE (STAT Rx USA LLC)
  Other
Formula
C15H13NO3. C4H11NO3
Exact mass
376.1634
Mol weight
376.4037
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Anti-inflammatory
 DG01906  Antiinflammatory drug, acetic acid derivatives
 DG01504  Nonsteroidal antiinflammatory drug (NSAID)
  DG01906  Antiinflammatory drug, acetic acid derivatives
Remark
ATC code: 
Chemical group: 
Activity
Analgesic, Anti-inflammatory, COX inhibitor
Comment
Non-steroidal anti-inflammatory drug (NSAID)
Target
PTGS1 (COX1) [HSA:5742] [KO:K00509];
PTGS2 (COX2) [HSA:5743] [KO:K11987]
  Pathway
Arachidonic acid metabolism
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
   M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
    M01AB Acetic acid derivatives and related substances
     M01AB15 Ketorolac
      D00813  Ketorolac tromethamine (USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BC Antiinflammatory agents, non-steroids
     S01BC05 Ketorolac
      D00813  Ketorolac tromethamine (USP)
USP drug classification [BR:br08302]
 Analgesics
  Nonsteroidal Anti-inflammatory Drugs
   Ketorolac
    D00813  Ketorolac tromethamine (USP)
 Anti-inflammatory Agents
  Nonsteroidal Anti-inflammatory Drugs
   Ketorolac
    D00813  Ketorolac tromethamine (USP)
 Ophthalmic Agents
  Ophthalmic Anti-inflammatories
   Ketorolac
    D00813  Ketorolac tromethamine (USP)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   cyclooxygenase-1 (COX-1)
    Ketorolac
     D00813  Ketorolac tromethamine (USP)
   cyclooxygenase-2 (COX-2)
    Ketorolac
     D00813  Ketorolac tromethamine (USP)
Anesthetics, analgesics and anti-inflammatory drugs [br08369.html]
 Anti-inflammatory drugs
  D00813
BRITE hierarchy
Other DBs
CAS: 
74103-07-4
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        27
            1   N4y N    19.2154  -20.8285
            2   C8y C    20.3375  -21.6701
            3   C8y C    18.0933  -21.6701
            4   C1x C    19.6362  -19.4961
            5   C1y C    21.5297  -20.8285
            6   C8x C    19.9167  -23.0025
            7   C5a C    16.9011  -20.9688
            8   C8x C    18.5141  -23.0025
            9   C1x C    21.0388  -19.4961
            10  C6a C    22.7219  -21.5298
            11  C8y C    15.6388  -21.6701
            12  O5a O    16.9011  -19.5662
            13  O6a O    23.9141  -20.8285
            14  O6a O    22.7219  -22.9324
            15  C8x C    15.6388  -23.0726
            16  C8x C    14.4466  -20.9688
            17  C8x C    14.4466  -23.7739
            18  C8x C    13.2544  -21.6701
            19  C8x C    13.2544  -23.0726
            20  C1d C    28.9634  -21.5999
            21  C1b C    27.7010  -20.8986
            22  C1b C    30.1556  -20.8986
            23  C1b C    28.9634  -23.0025
            24  N1a N    28.9634  -20.1973
            25  O1a O    26.5088  -21.5999
            26  O1a O    31.3478  -21.5999
            27  O1a O    30.1556  -23.7038
BOND        28
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     3   8 2
            8     4   9 1
            9     5  10 1
            10    7  11 1
            11    7  12 2
            12   10  13 1
            13   10  14 2
            14   11  15 2
            15   11  16 1
            16   15  17 1
            17   16  18 2
            18   17  19 2
            19    5   9 1
            20    6   8 1
            21   18  19 1
            22   20  21 1
            23   20  22 1
            24   20  23 1
            25   20  24 1
            26   21  25 1
            27   22  26 1
            28   23  27 1

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