KEGG   DRUG: Bupropion hydrochlorideHelp
Entry
D00817                      Drug                                   

Name
Bupropion hydrochloride (JAN/USP);
Wellbutrin (TN);
Zyban (TN)
Product
  Generic
BUPROPION (BluePoint Laboratories), BUPROPION (BluePoint Laboratories), BUPROPION (Cadila Healthcare Limited), BUPROPION (Preferred Pharmaceuticals), BUPROPION (Proficient Rx LP), BUPROPION (REMEDYREPACK), BUPROPION (Zydus Pharmaceuticals (USA)), WELLBUTRIN SR (DIRECT RX), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (Actavis Pharma), BUPROPION HYDROCHLORIDE (Actavis Pharma), BUPROPION HYDROCHLORIDE (Actavis Pharma), BUPROPION HYDROCHLORIDE (Actavis Pharma), BUPROPION HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), BUPROPION HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), BUPROPION HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), BUPROPION HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), BUPROPION HYDROCHLORIDEXL (Aidarex Pharmaceuticals LLC), BUPROPION HYDROCHLORIDE SR (Aidarex Pharmaceuticals LLC), BUPROPION HYDROCHLORIDE (American Health Packaging), BUPROPION HYDROCHLORIDE (American Health Packaging), BUPROPION HYDROCHLORIDE (American Health Packaging), BUPROPION HYDROCHLORIDE (American Health Packaging), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Apotex Corp), BUPROPION HYDROCHLORIDE (AvKARE), BUPROPION HYDROCHLORIDE (AvPAK), BUPROPION HYDROCHLORIDE (AvPAK), BUPROPION HYDROCHLORIDE (BluePoint Laboratories), BUPROPION HYDROCHLORIDE (BluePoint Laboratories), BUPROPION HYDROCHLORIDE (BluePoint Laboratories), BUPROPION HYDROCHLORIDE (BluePoint Laboratories), BUPROPION HYDROCHLORIDE (BluePoint Laboratories), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUDEPRION (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUDEPRION (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (CIPLA USA INC.,), BUDEPRION (Cardinal Health), BUPROPION HYDROCHLORIDE (Cardinal Health), BUPROPION HYDROCHLORIDE (Cardinal Health), BUPROPION HYDROCHLORIDE (Cardinal Health), BUPROPION HYDROCHLORIDE (SR) (Cipla USA Inc.,), BUPROPION HYDROCHLORIDE (Clinical Solutions Wholesale), BUPROPION HYDROCHLORIDE (Contract Pharmacy Services-PA), BUPROPION HYDROCHLORIDE (Contract Pharmacy Services-PA), BUPROPION HYDROCHLORIDE (Contract Pharmacy Services-PA), BUPROPION HYDROCHLORIDE (Contract Pharmacy Services-PA), BUPROPION HYDROCHLORIDE (Contract Pharmacy Services-PA), BUPROPION HYDROCHLORIDE (Contract Pharmacy Services-PA), BUPROPION HYDROCHLORIDE (DIRECT RX), BUPROPION HYDROCHLORIDE (DIRECT RX), BUPROPION HYDROCHLORIDE (DIRECT RX), BUPROPION HYDROCHLORIDE (Direct Rx), BUPROPION HYDROCHLORIDE (DirectRX), BUPROPION HYDROCHLORIDE (Dispensing Solutions), BUPROPION HYDROCHLORIDE (Dispensing Solutions), BUPROPION HYDROCHLORIDE (Dispensing Solutions), BUPROPION HYDROCHLORIDE (Dispensing Solutions), BUPROPION HYDROCHLORIDE (Dr Reddys Laboratories), BUPROPION HYDROCHLORIDE (Dr. Reddy's Laboratories), BUPROPION HYDROCHLORIDE (Eon Labs), BUPROPION HYDROCHLORIDE (Epic Pharma), BUPROPION HYDROCHLORIDE (Exelan Pharmaceuticals), BUPROPION HYDROCHLORIDE (Golden State Medical Supply), BUPROPION HYDROCHLORIDE (Golden State Medical Supply), BUPROPION HYDROCHLORIDE (Golden State Medical Supply), BUPROPION HYDROCHLORIDE (Golden State Medical Supply), BUPROPION HYDROCHLORIDE (H.J. Harkins Company), BUPROPION HYDROCHLORIDE (H.J. Harkins Company), BUPROPION HYDROCHLORIDE (Heritage Pharmaceuticals), BUPROPION HYDROCHLORIDE (Impax Generics), BUPROPION HYDROCHLORIDE (Impax Generics), BUPROPION HYDROCHLORIDE (Jubilant Cadista Pharmaceuticals), BUPROPION HYDROCHLORIDE (Jubilant Cadista Pharmaceuticals), BUPROPION HYDROCHLORIDE (KAISER FOUNDATION HOSPITALS), BUPROPION HYDROCHLORIDE (KAISER FOUNDATION HOSPITALS), BUPROPION HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), BUPROPION HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), BUPROPION HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), BUPROPION HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), BUPROPION HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), BUPROPION HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), BUPROPION HYDROCHLORIDE (Liberty Pharmaceuticals), BUPROPION HYDROCHLORIDE (Lupin Pharmaceuticals), BUPROPION HYDROCHLORIDE (Major Pharmaceuticals), BUPROPION HYDROCHLORIDE (Major Pharmaceuticals), BUPROPION HYDROCHLORIDE (Major Pharmaceuticals), BUPROPION HYDROCHLORIDE (McKesson Packaging Services a busines unit of McKeson Corporation), BUPROPION HYDROCHLORIDE (McKesson Packing Services a business of McKesson Corporation), BUPROPION HYDROCHLORIDE (Medsource Pharmaceuticals), BUPROPION HYDROCHLORIDE (Medsource Pharmaceuticals), BUPROPION HYDROCHLORIDE (Mylan Institutional), BUPROPION HYDROCHLORIDE (Mylan Institutional), BUPROPION HYDROCHLORIDE (Mylan Institutional), BUPROPION HYDROCHLORIDE (Mylan Pharmaceuticals), BUPROPION HYDROCHLORIDE (Mylan Pharmaceuticals), BUPROPION HYDROCHLORIDE (Mylan Pharmaceuticals), BUPROPION HYDROCHLORIDE (Mylan Pharmaceuticals), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUDEPRION XL (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (Northwind Pharmaceuticals), BUPROPION HYDROCHLORIDE (NuCare Pharmaceuticals), BUPROPION HYDROCHLORIDE (NuCare Pharmaceuticals), BUPROPION HYDROCHLORIDE (NuCare Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (Par Pharmaceutical), BUPROPION HYDROCHLORIDE (Physicians Total Care), BUPROPION HYDROCHLORIDE (Physicians Total Care), BUPROPION (Physicians Total Care), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (Rebel Distributors Corp), BUPROPION HYDROCHLORIDE (Rebel Distributors Corp), BUPROPION HYDROCHLORIDE (Rebel Distributors Corp.), BUPROPION HYDROCHLORIDE (Rebel Distributors Corp.), BUPROPION HYDROCHLORIDE (RxChange), BUPROPION HYDROCHLORIDE (STAT RX USA LLC), BUPROPION HYDROCHLORIDE (STAT RX USA LLC), BUDEPRION (STAT RX USA LLC), BUPROPION HYDROCHLORIDE (Sandoz), BUPROPION HYDROCHLORIDE (Sandoz), BUPROPION HYDROCHLORIDE (ScieGen Pharmaceuticals), BUPROPION HYDROCHLORIDE (ScieGen Pharmaceuticals), BUPROPION (Solco Healthcare US LLC), BUPROPION HYDROCHLORIDE (St Marys Medical Park Pharmacy), BUPROPION HYDROCHLORIDE (St Marys Medical Park Pharmacy), BUPROPION HYDROCHLORIDE (St Marys Medical Park Pharmacy), BUPROPION HYDROCHLORIDE (State of Florida DOH Central Pharmacy), BUPROPION HYDROCHLORIDE (State of Florida DOH Central Pharmacy), BUPROPION HYDROCHLORIDE (State of Florida DOH Central Pharmacy), BUPROPION HYDROCHLORIDE (State of Florida DOH Central Pharmacy), BUPROPION HYDROCHLORIDE (Sun Pharma Global FZE), BUPROBAN (TEVA Pharmaceuticals USA), BUPROPION HYDROCHLORIDE (TYA Pharmaceuticals), BUPROPION HYDROCHLORIDE (TYA Pharmaceuticals), BUPROPION HYDROCHLORIDE (Torrent Pharmaceuticals Limited), BUPROPION HYDROCHLORIDE (Unit Dose Services), BUPROPION HYDROCHLORIDE (Unit Dose Services), BUPROPION HYDROCHLORIDE (Wockhardt Limited), BUPROPION HYDROCHLORIDE (Wockhardt Limited), BUPROPION HYDROCHLORIDE (Wockhardt USA LLC.), BUPROPION HYDROCHLORIDE (Wockhardt USA LLC.), BUPROPION HYDROCHLORIDE (XL) (DIRECT RX), BUPROPION HYDROCHLORIDE (Jubilant Cadista Pharmaceuticals)
Formula
C13H18ClNO. HCl
Exact mass
275.0844
Mol weight
276.2021
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cyp inhibitor
 DG01645  CYP2D6 inhibitor
Remark
ATC code: 
Chemical group: 
Efficacy
Antidepressant
Comment
dopamine noradrenalin selective reuptake inhibitor (DNRI)
Metabolism
Enzyme: CYP2B6 [HSA:1555]
Interaction
CYP inhibition: CYP2D6 [HSA:1565]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AX Other antidepressants
     N06AX12 Bupropion
      D00817  Bupropion hydrochloride (JAN/USP)
USP drug classification [BR:br08302]
 Anti-Addiction/Substance Abuse Treatment Agents
  Smoking Cessation Agents
   Bupropion
    D00817  Bupropion hydrochloride (JAN/USP)
 Antidepressants
  Antidepressants, Other
   Bupropion
    D00817  Bupropion hydrochloride (JAN/USP)
Cytochrome P450 interactions [BR:br08309]
 CYP inhbitors
  CYP2D6
   Bupropion
    D00817  Bupropion hydrochloride (JAN/USP)
 CYP substrates
  CYP2B6
   Bupropion
    D00817  Bupropion hydrochloride (JAN/USP)
Psychiatric agents [br08363.html]
 Antidepressants
  D00817
BRITE hierarchy
Other DBs
CAS: 
31677-93-7
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        17
            1   C8y C    15.4700  -16.1700
            2   C5a C    16.7300  -15.4700
            3   C8x C    14.2800  -15.4700
            4   C8x C    15.4700  -17.5700
            5   C1c C    17.9200  -16.1700
            6   O5a O    16.7300  -14.0700
            7   C8y C    13.0900  -16.1700
            8   C8x C    14.2800  -18.2700
            9   N1b N    19.1100  -15.4700
            10  C1a C    17.9200  -17.5700
            11  C8x C    13.0900  -17.5700
            12  X   Cl   11.9000  -15.4700
            13  C1d C    20.3700  -16.1700
            14  C1a C    21.5600  -15.4700
            15  C1a C    20.3700  -17.5700
            16  C1a C    21.5600  -16.9400
            17  X   Cl   25.3400  -15.4700
BOND        16
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     4   8 2
            8     5   9 1
            9     5  10 1
            10    7  11 2
            11    7  12 1
            12    9  13 1
            13   13  14 1
            14   13  15 1
            15   13  16 1
            16    8  11 1

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