KEGG   DRUG: D00817Help
Entry
D00817                      Drug                                   
Name
Bupropion hydrochloride (JAN/USP);
Wellbutrin (TN);
Zyban (TN)
Product
  Generic
BUPROPION HYDROCHLORIDE (Actavis South Atlantic LLC), BUPROPION HYDROCHLORIDE (Actavis South Atlantic LLC), BUPROPION HYDROCHLORIDE (Actavis South Atlantic LLC), BUPROPION HYDROCHLORIDE (American Health Packaging), BUPROPION HYDROCHLORIDE (American Health Packaging), BUPROPION HYDROCHLORIDE (American Health Packaging), BUPROPION HYDROCHLORIDE (Anchen Pharmaceuticals), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Apotex Corp), BUDEPRION (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUDEPRION (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUDEPRION (Cardinal Health), BUPROPION HYDROCHLORIDE (Cardinal Health), BUPROPION HYDROCHLORIDE (Cardinal Health), BUPROPION HYDROCHLORIDE (Contract Pharmacy Services-PA), BUPROPION HYDROCHLORIDE (Contract Pharmacy Services-PA), BUPROPION HYDROCHLORIDE (Dispensing Solutions), BUPROPION HYDROCHLORIDE (Dispensing Solutions), BUPROPION HYDROCHLORIDE (Dispensing Solutions), BUPROPION HYDROCHLORIDE (Eon Labs), BUPROPION HYDROCHLORIDE (Global Pharmaceuticals), BUPROPION HYDROCHLORIDE (Global Pharmaceuticals), BUPROPION HYDROCHLORIDE (Golden State Medical Supply), BUPROPION HYDROCHLORIDE (Golden State Medical Supply), BUPROPION HYDROCHLORIDE (Golden State Medical Supply), BUPROPION HYDROCHLORIDE (H.J. Harkins Company), BUPROPION HYDROCHLORIDE (H.J. Harkins Company), BUPROPION HYDROCHLORIDE (KAISER FOUNDATION HOSPITALS), BUPROPION HYDROCHLORIDE (KAISER FOUNDATION HOSPITALS), BUPROPION HYDROCHLORIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), BUPROPION HYDROCHLORIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), BUPROPION HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), BUPROPION HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), BUPROPION HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), BUPROPION HYDROCHLORIDE (Major Pharmaceuticals), BUPROPION HYDROCHLORIDE (McKesson Packaging Services Business Unit of McKesson Corporation), BUPROPION HYDROCHLORIDE (Mylan Institutional), BUPROPION HYDROCHLORIDE (Mylan Pharmaceuticals), BUPROPION HYDROCHLORIDE (Mylan Pharmaceuticals), BUPROPION HYDROCHLORIDE (Mylan Pharmaceuticals), BUPROPION HYDROCHLORIDE (Mylan Pharmaceuticals), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUDEPRION XL (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NorthStar RX LLC), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (Par Pharmaceutical), BUPROPION HYDROCHLORIDE (Par Pharmaceuticals), BUPROPION HYDROCHLORIDE (Physicians Total Care), BUPROPION HYDROCHLORIDE (Physicians Total Care), BUPROPION (Physicians Total Care), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (Rebel Distributors Corp), BUPROPION HYDROCHLORIDE (Rebel Distributors Corp), BUPROPION HYDROCHLORIDE (Rebel Distributors Corp.), BUPROPION HYDROCHLORIDE (Rebel Distributors Corp.), BUPROPION HYDROCHLORIDE (STAT RX USA LLC), BUPROPION HYDROCHLORIDE (STAT RX USA LLC), BUDEPRION (STAT RX USA LLC), BUPROPION HYDROCHLORIDE (Sandoz), BUPROPION HYDROCHLORIDE (Sandoz), BUPROPION HYDROCHLORIDE (State of Florida DOH Central Pharmacy), BUPROPION HYDROCHLORIDE (State of Florida DOH Central Pharmacy), BUPROPION HYDROCHLORIDE (State of Florida DOH Central Pharmacy), BUPROPION HYDROCHLORIDE (Sun Pharma Global FZE), BUPROBAN (TEVA Pharmaceuticals USA), BUDEPRION (TEVA Pharmaceuticals USA), BUDEPRION (Teva Pharmaceuticals USA), BUDEPRION (Teva Pharmaceuticals USA), BUPROPION HYDROCHLORIDE (UDL Laboratories), BUPROPION HYDROCHLORIDE (UDL Laboratories), BUPROPION HYDROCHLORIDE (Unit Dose Services), BUPROPION HYDROCHLORIDE (Unit Dose Services), BUPROPION HYDROCHLORIDE (Unit Dose Services), BUPROPION HYDROCHLORIDE (Watson Laboratories), BUPROPION HYDROCHLORIDE (Watson Laboratories), BUPROPION HYDROCHLORIDE (Watson Laboratories), BUPROPION HYDROCHLORIDE (Wockhardt Limited), BUPROPION HYDROCHLORIDE (Wockhardt Limited), BUPROPION HYDROCHLORIDE (Wockhardt USA LLC.), BUPROPION HYDROCHLORIDE (Wockhardt USA LLC.), CAPTOPRIL (State of Florida DOH Central Pharmacy)
Formula
C13H18ClNO. HCl
Exact mass
275.0844
Mol weight
276.2021
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant
Remark
ATC code: 
Comment
dopamine noradrenalin selective reuptake inhibitor (DNRI)
Metabolism
Enzyme: CYP2B6 [HSA:1555]
Interaction
CYP inhibition: CYP2D6 [HSA:1565]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AX Other antidepressants
     N06AX12 Bupropion
      D00817  Bupropion hydrochloride (JAN/USP)
USP drug classification [BR:br08302]
 Anti-Addiction / Substance Abuse Treatment Agents
  Smoking Cessation Agents
   Bupropion
    D00817  Bupropion hydrochloride (JAN/USP)
 Antidepressants
  Antidepressants, Other
   Bupropion
    D00817  Bupropion hydrochloride (JAN/USP)
BRITE hierarchy
Other DBs
CAS: 
31677-93-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        17
            1   C8y C    15.4700  -16.1700
            2   C5a C    16.7300  -15.4700
            3   C8x C    14.2800  -15.4700
            4   C8x C    15.4700  -17.5700
            5   C1c C    17.9200  -16.1700
            6   O5a O    16.7300  -14.0700
            7   C8y C    13.0900  -16.1700
            8   C8x C    14.2800  -18.2700
            9   N1b N    19.1100  -15.4700
            10  C1a C    17.9200  -17.5700
            11  C8x C    13.0900  -17.5700
            12  X   Cl   11.9000  -15.4700
            13  C1d C    20.3700  -16.1700
            14  C1a C    21.5600  -15.4700
            15  C1a C    20.3700  -17.5700
            16  C1a C    21.5600  -16.9400
            17  X   Cl   25.3400  -15.4700
BOND        16
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     4   8 2
            8     5   9 1
            9     5  10 1
            10    7  11 2
            11    7  12 1
            12    9  13 1
            13   13  14 1
            14   13  15 1
            15   13  16 1
            16    8  11 1

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