KEGG   DRUG: Oxycodone hydrochlorideHelp
Entry
D00847                      Drug                                   

Name
Oxycodone hydrochloride (USP);
Oxecta (TN);
Oxycontin (TN);
Roxicodone (TN)
Product
XTAMPZA (Collegium Pharmaceutical), XTAMPZA (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HCL CONTROLLED-RELEASE (Ranbaxy Pharmaceuticals), OXYCONTIN (Bryant Ranch Prepack), OXYCONTIN (Bryant Ranch Prepack), ROXYBOND (Daiichi Sankyo), OXAYDO (Egalet US), OXYCODONE HYDROCHLORIDE (Genus Lifesciences), OXYCODONE HYDROCHLORIDE (Genus Lifesciences), ROXYBOND (Inspirion Delivery Sciences Llc), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCONTIN (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXAYDO (Lake Erie Medical DBA Quality Care Products LLC), OXYCONTIN (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCONTIN (PD-Rx Pharmaceuticals), OXECTA (Pfizer Laboratories Div Pfizer), OXYCONTIN (Purdue Pharma LP), OXYCODONE HCL (Ranbaxy Pharmaceuticals), OXYCONTIN (Rebel Distributors Corp), OXYCONTIN (Rebel Distributors Corp), OXYCONTIN (Rebel Distributors Corp), OXYCODONE HYDROCHLORIDE (RedPharm Drug), ROXICODONE (SpecGx LLC), OXYCODONE HYDROCHLORIDE (VistaPharm)
  Generic
OXYCODONE HYDROCHLORIDE (Amneal Pharmaceuticals LLC), OXYCODONE HCL (DIRECT RX), OXYCODONE HCL (DIRECT RX), OXYCODONE HCL (DIRECT RX), OXYCODONE HYDCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (ANI Pharmaceuticals), OXYCODONE HYDROCHLORIDE (ANI Pharmaceuticals), OXYCODONE HYDROCHLORIDE (ANI Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Actavis Pharma), OXYCODONE HYDROCHLORIDE (Actavis Pharma), OXYCODONE HYDROCHLORIDE (Alvogen), OXYCODONE HYDROCHLORIDE (American Health Packaging), OXYCODONE HYDROCHLORIDE (American Health Packaging), OXYCODONE HYDROCHLORIDE (American Health Packaging), OXYCODONE HYDROCHLORIDE (American Health Packaging), OXYCODONE HYDROCHLORIDE (Atlantic Biologicals Corps), OXYCODONE HYDROCHLORIDE (Aurolife Pharma LLC), OXYCODONE HYDROCHLORIDE (Blenheim Pharmacal), OXYCODONE HYDROCHLORIDE (Blenheim Pharmacal), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Camber Pharmaceuticals), OXYCODONE HYDROCHLORIDE (CorePharma), OXYCODONE HYDROCHLORIDE (DIRECT RX), OXYCODONE HYDROCHLORIDE (DIRECT RX), OXYCODONE HYDROCHLORIDE (Dispensing Solutions), OXYCODONE HYDROCHLORIDE (Epic Pharma), OXYCODONE HYDROCHLORIDE (Ethex Corporation), OXYCODONE HYDROCHLORIDE (Glenmark Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Glenmark Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Golden State Medical Supply), OXYCODONE HYDROCHLORIDE (H.J. Harkins Company), OXYCODONE HYDROCHLORIDE (H.J. Harkins Company), OXYCODONE HYDROCHLORIDE (Hi-Tech Pharmacal), OXYCODONE HYDROCHLORIDE (Hi-Tech Pharmacal), OXYCODONE HYDROCHLORIDE (Impax Generics), OXYCODONE HYDROCHLORIDE (KVK-TECH), OXYCODONE HYDROCHLORIDE (KVK-TECH), OXYCODONE HYDROCHLORIDE (KVK-Tech), OXYCODONE HYDROCHLORIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lannett Company), OXYCODONE HYDROCHLORIDE (Lannett Company), OXYCODONE HYDROCHLORIDE (Lohxa), OXYCODONE HYDROCHLORIDE (Lupin Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Major Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Major Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Major Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Major Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Major Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Mayne Pharma), OXYCODONE HYDROCHLORIDE (Mayne Pharma), OXYCODONE HYDROCHLORIDE (Mayne Pharma), OXYCODONE HYDROCHLORIDE (McKesson Corporation), OXYCODONE HYDROCHLORIDE (Morton Grove Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Mylan Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Novel Laboratories), OXYCODONE HYDROCHLORIDE (Novel Laboratories), OXYCODONE HYDROCHLORIDE (Novel Laboratories), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Par Pharmaceutical), OXYCODONE HYDROCHLORIDE (Par Pharmaceutical), OXYCODONE HYDROCHLORIDE (Pharmaceutical Associates), OXYCODONE HYDROCHLORIDE (Physicians Total Care), OXYCODONE HYDROCHLORIDE (Physicians Total Care), OXYCODONE HYDROCHLORIDE (Precision Dose), OXYCODONE HYDROCHLORIDE (Precision Dose), OXYCODONE HYDROCHLORIDE (Precision Dose), OXYCODONE HYDROCHLORIDE (Rebel Distributors Corp), OXYCODONE HYDROCHLORIDE (RedPharm Drug), OXYCODONE HYDROCHLORIDE (RedPharm Drug), OXYCODONE HYDROCHLORIDE (RedPharm Drug), OXYCODONE HYDROCHLORIDE (RedPharm Drug), OXYCODONE HYDROCHLORIDE (Rhodes Pharmaceuticals L.P.), OXYCODONE HYDROCHLORIDE (Roxane Laboratories), OXYCODONE HYDROCHLORIDE (Safecor Health), OXYCODONE HYDROCHLORIDE (Sandoz), OXYCODONE HYDROCHLORIDE (SpecGx LLC), OXYCODONE HYDROCHLORIDE (St Marys Medical Park Pharmacy), OXYCODONE HYDROCHLORIDE (St Marys Medical Park Pharmacy), OXYCODONE HYDROCHLORIDE (Sun Pharmaceutical Industries), OXYCODONE HYDROCHLORIDE (Teva Pharmaceuticals USA), OXYCODONE HYDROCHLORIDE (Unit Dose Services), OXYCODONE HYDROCHLORIDE (Unit Dose Services), OXYCODONE HYDROCHLORIDE (Unit Dose Services), OXYCODONE HYDROCHLORIDE (VistaPharm), OXYCODONE HYDROCHLORIDE (West-Ward Pharmaceuticals Corp.), OXYCODONE HYDROCHLORIDE (West-Ward Pharmaceuticals Corp.), OXYCODONE HYDROCHLORIDE (Zydus Pharmaceuticals (USA)), OXYCODONE HYDROCHLORIDE (bryant ranch prepack), OXYCODONE HYDROCHLORIDE (bryant ranch prepack)
Formula
C18H21NO4. HCl
Exact mass
351.1237
Mol weight
351.8246
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Cyp substrate
 DG01644  CYP2D6 substrate
 DG01633  CYP3A substrate
Remark
Same as: 
ATC code: 
Chemical structure group: 
Product in DG00813: 
D00847<US> D02175<JP> D05462<JP>
Product in mixture: 
D02153<US> D02154<US>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Comment
Opium alkaloid
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
Neuroactive ligand-receptor interaction
Metabolism
Enzyme: CYP3A4 [HSA:1576]; CYP2D6 [HSA:1565]
Interaction
Drug interaction
Structure map
Opioid analgesics
Opioid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AA Natural opium alkaloids
     N02AA05 Oxycodone
      D00847  Oxycodone hydrochloride (USP)
USP drug classification [BR:br08302]
 Analgesics
  Opioid Analgesics, Long-acting
   Oxycodone
    D00847  Oxycodone hydrochloride (USP)
  Opioid Analgesics, Short-acting
   Oxycodone
    D00847  Oxycodone hydrochloride (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    mu-opioid receptor
     Oxycodone
      D00847  Oxycodone hydrochloride (USP)
    kappa-opioid receptor
     Oxycodone
      D00847  Oxycodone hydrochloride (USP)
Drug classes of therapeutic agents [br08360.html]
 Anesthetics, analgesics and anti-inflammatory drugs
  D00847
BRITE hierarchy
Other DBs
CAS: 
124-90-3
PubChem: 
ChEBI: 
ChEMBL: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        24
            1   C1z C    24.4381  -17.6672
            2   C8y C    24.4321  -16.3168
            3   C1z C    25.6030  -18.3338
            4   C1y C    23.2847  -18.3454
            5   C8y C    23.2672  -15.6445
            6   C8y C    25.5972  -15.6445
            7   C1y C    26.7623  -17.6499
            8   C1x C    25.6087  -19.6668
            9   O1a O    26.7623  -19.2729
            10  O2x O    22.5833  -17.0126
            11  C5x C    23.2905  -19.6784
            12  C8y C    23.2672  -14.2999
            13  C1x C    26.7623  -16.3109
            14  C8x C    25.5972  -14.2999
            15  N1y N    27.9213  -18.3221
            16  C1x C    24.4554  -20.3450
            17  O5x O    22.1139  -20.3391
            18  C8x C    24.4321  -13.6277
            19  O2a O    22.0966  -13.6277
            20  C1a C    29.2659  -18.3221
            21  C1x C    27.9213  -16.9998
            22  C1x C    25.6435  -17.0412
            23  C1a C    20.8657  -14.3423
            24  X   Cl   29.6100  -14.9100
BOND        27
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     3   8 1
            8     3   9 1 #Up
            9     4  10 1 #Down
            10    4  11 1
            11    5  12 2
            12    6  13 1
            13    6  14 1
            14    7  15 1 #Up
            15    8  16 1
            16   11  17 2
            17   12  18 1
            18   12  19 1
            19   15  20 1
            20    5  10 1
            21    7  13 1
            22   11  16 1
            23   14  18 2
            24   15  21 1
            25    1  22 1 #Up
            26   22  21 1
            27   19  23 1

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