KEGG   DRUG: Naftifine hydrochlorideHelp
Entry
D00883                      Drug                                   

Name
Naftifine hydrochloride (USP);
Naftin (TN)
Product
  Generic
Formula
C21H21N. HCl
Exact mass
323.1441
Mol weight
323.8591
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Remark
Same as: C08072
ATC code: D01AE22
Chemical structure group: DG00377
Product (DG00377): D00883<US>
Efficacy
Antifungal, Ergosterol biosynthesis inhibitor
Comment
Allylamine derivative
Target
squalene epoxidase [KO:K00511]
  Pathway
ko00100  Steroid biosynthesis
Structure map
map07026  Antifungal agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AE Other antifungals for topical use
     D01AE22 Naftifine
      D00883  Naftifine hydrochloride (USP) <US>
USP drug classification [BR:br08302]
 Antifungals
  Naftifine
   D00883  Naftifine hydrochloride (USP)
Antiinfectives [br08350.html]
 Antifungals
  D00883
BRITE hierarchy
Other DBs
CAS: 65473-14-5
PubChem: 7847947
ChEBI: 7452
ChEMBL: CHEMBL1200493
DrugBank: DB00735
LigandBox: D00883
NIKKAJI: J244.941B
LinkDB All DBs
KCF data Show

ATOM        23
            1   C8x C    23.6600  -25.4100
            2   C8x C    23.6600  -26.8100
            3   C8x C    24.8724  -27.5100
            4   C8y C    26.0849  -26.8100
            5   C8y C    26.0849  -25.4100
            6   C8x C    24.8724  -24.7100
            7   C8x C    27.2973  -27.5100
            8   C8x C    28.5097  -26.8100
            9   C8x C    28.5097  -25.4100
            10  C8y C    27.2973  -24.7100
            11  C1b C    27.2973  -23.3100
            12  N1c N    28.5118  -22.6088
            13  C1b C    29.7083  -23.2998
            14  C1a C    28.5118  -21.2102
            15  C2b C    30.8951  -22.6146
            16  C2b C    32.0866  -23.3028
            17  C8y C    33.2760  -22.6161
            18  C8x C    34.4662  -23.3035
            19  C8x C    35.6787  -22.6037
            20  C8x C    35.6789  -21.2037
            21  C8x C    34.4887  -20.5163
            22  C8x C    33.2762  -21.2161
            23  X   Cl   34.5800  -26.5300
BOND        24
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12   10  11 1
            13   11  12 1
            14   12  13 1
            15   12  14 1
            16   13  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   20  21 1
            23   21  22 2
            24   17  22 1

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