KEGG   DRUG: D00905Help
Entry
D00905                      Drug                                   
Name
Cefazolin sodium (JP16/USP);
Ancef (TN)
Product
  Generic
CEFAZOLIN (APP Pharmaceuticals), CEFAZOLIN (Apotex Corp), CEFAZOLIN (Apotex Corp), CEFAZOLIN (Cardinal Health), CEFAZOLIN (Cardinal Health), CEFAZOLIN (Cardinal Health), CEFAZOLIN (Cardinal Health), CEFAZOLIN (Cardinal Health), CEFAZOLIN (General Injectables & Vaccines), CEFAZOLIN (General Injectables & Vaccines), CEFAZOLIN (Hospira), CEFAZOLIN (Hospira), CEFAZOLIN (Hospira), CEFAZOLIN (Sandoz), CEFAZOLIN (Sandoz), CEFAZOLIN (Sandoz), CEFAZOLIN (Sandoz), CEFAZOLIN (WG Critical Care), CEFAZOLIN (WG Critical Care), CEFAZOLIN (West-Ward Pharmaceutical Corp), CEFAZOLIN (West-ward Pharmaceutical Corp), CEFAZOLIN (APP Pharmaceuticals), CEFAZOLIN (APP Pharmaceuticals), CEFAZOLIN (Baxter Healthcare Corporation), CEFAZOLIN (Dispensing Solutions), CEFAZOLIN (General Injectables & Vaccines), CEFAZOLIN (General Injectables & Vaccines), CEFAZOLIN (Physicians Total Care), CEFAZOLIN (Sagent Pharmaceuticals), CEFAZOLIN (Sagent Pharmaceuticals), CEFAZOLIN (Samson Medical Technologies)
  Other
Formula
C13H16N9O4S3. Na
Exact mass
481.0385
Mol weight
481.5088
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial [systemic]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Comment
Semisynthetic cephalosporin: narrow spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Structure map
Cephalosporins - parenteral agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6132  Cephem antibioitics
     D00905  Cefazolin sodium (JP16/USP)
 7  Agents not mainly for therapeutic purpose
  72  Intracorporeal diagnostic agents
   729  Miscellaneous
    7290  Miscellaneous
     D00905  Cefazolin sodium (JP16/USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DB First-generation cephalosporins
     J01DB04 Cefazolin
      D00905  Cefazolin sodium (JP16/USP)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cephalosporin Antibacterials, 1st Generation
    Cefazolin
     D00905  Cefazolin sodium (JP16/USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefazolin [ATC:J01DB04]
      D00905  Cefazolin sodium (JP16/USP)
BRITE hierarchy
Other DBs
CAS: 
27164-46-1
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   C1y C    26.5187  -14.5749
            2   N1y N    26.5187  -15.9706
            3   C2y C    27.7276  -16.6683
            4   C2y C    28.9363  -15.9706
            5   C1x C    28.9363  -14.5749
            6   S2x S    27.7276  -13.8770
            7   C1y C    25.1229  -14.5749
            8   C5x C    25.1229  -15.9706
            9   N1b N    23.9143  -13.8770
            10  C5a C    22.7054  -14.5749
            11  O5a O    22.7054  -15.9706
            12  O5x O    23.9143  -16.6683
            13  C1b C    21.4966  -13.8770
            14  C1b C    30.1635  -16.6795
            15  C6a C    27.7276  -18.0639
            16  O6a O    26.5019  -18.7716
            17  O6a O    28.9193  -18.7521 #-
            18  N1y N    20.2685  -14.5865
            19  S2a S    31.3771  -15.9790
            20  C8y C    32.5855  -16.6770
            21  N5x N    33.0093  -18.0051
            22  N5x N    34.4060  -18.0165
            23  N4y N    34.8484  -16.6917
            24  S2x S    33.7252  -15.8615
            25  C1a C    36.2444  -16.6729
            26  C1x C    19.1169  -13.7756
            27  N2x N    17.9853  -14.6205
            28  N2x N    18.4390  -15.9579
            29  N2x N    19.8511  -15.9398
            30  Z   Na   30.3794  -18.6897 #+
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   14  19 1
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   23  24 1
            26   20  24 1
            27   23  25 1
            28   18  26 1
            29   26  27 1
            30   27  28 2
            31   28  29 1
            32   18  29 2

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