KEGG   DRUG: EntecavirHelp
Entry
D04008                      Drug                                   

Name
Entecavir (USAN);
Entecavir hydrate (JAN);
Baraclude (TN)
Product
  Generic
Formula
C12H15N5O3. H2O
Exact mass
295.1281
Mol weight
295.2945
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Antiviral
 DG01890  Nucleoside reverse transcriptase inhibitor (NRTI)
Remark
Therapeutic category: 6250
ATC code: J05AF10
Chemical structure group: DG00661
Product (DG00661): D04008<JP/US>
Efficacy
Antiviral, Reverse transcriptase inhibitor
  Disease
Hepatitis B [DS:H00412]
Target
RNA-directed DNA polymerase
Structure map
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
     J05AF10 Entecavir
      D04008  Entecavir (USAN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-hepatitis B (HBV) Agents
   Entecavir
    D04008  Entecavir (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D04008  Entecavir (USAN); Entecavir hydrate (JAN)
Antiinfectives [br08350.html]
 Antivirals
  D04008
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D04008
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D04008
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D04008
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D04008
BRITE hierarchy
Other DBs
CAS: 209216-23-9
PubChem: 17398002
ChEBI: 59902
DrugBank: DB00442
LigandBox: D04008
LinkDB All DBs
KCF data Show

ATOM        21
            1   O0  O    30.7234  -17.2838
            2   C8y C    23.0300  -15.3300
            3   C8y C    23.0300  -16.8000
            4   C8y C    24.0100  -14.6300
            5   N5x N    21.7000  -14.9800
            6   N4y N    21.7700  -17.2900
            7   N5x N    24.2200  -17.4300
            8   O5x O    24.0100  -13.2300
            9   N4x N    25.3400  -15.1900
            10  C8x C    20.8600  -16.1700
            11  C1y C    20.1600  -18.4100
            12  C8y C    25.3400  -16.7300
            13  C2y C    19.0400  -17.5700
            14  C1x C    19.6700  -19.6000
            15  N1a N    26.6000  -17.2900
            16  C1y C    17.9200  -18.2700
            17  C1y C    18.3400  -19.6000
            18  C1b C    16.6600  -17.8500
            19  O1a O    15.6100  -18.6900
            20  C2a C    19.0400  -16.1700
            21  O1a O    17.5000  -20.7200
BOND        22
            1     2   3 2
            2     2   4 1
            3     2   5 1
            4     3   6 1
            5     3   7 1
            6     4   8 2
            7     4   9 1
            8     5  10 2
            9    11   6 1 #Up
            10    7  12 2
            11   11  13 1
            12   11  14 1
            13   12  15 1
            14   13  16 1
            15   14  17 1
            16   16  18 1 #Up
            17   18  19 1
            18    6  10 1
            19    9  12 1
            20   16  17 1
            21   13  20 2
            22   17  21 1 #Down

» Japanese version   » Back

DBGET integrated database retrieval system