KEGG   DRUG: Valsartan - amlodipine besilate mixtHelp
Entry
D09745            Mixture   Drug                                   

Name
Valsartan - amlodipine besilate mixt;
Exforge (TN)
Product
  Generic
Component
Valsartan [DR:D00400], Amlodipine besilate [DR:D00615]
Class
Cardiovascular agent
 DG01925  Renin-angiotensin system inhibitor
Cyp substrate
 DG01633  CYP3A substrate
Remark
Therapeutic category: 
ATC code: 
Activity
Antihypertensive
  Disease
Hypertension [DS:H01633]
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09D ANGIOTENSIN II ANTAGONISTS, COMBINATIONS
    C09DB Angiotensin II antagonists and calcium channel blockers
     C09DB01 Valsartan and amlodipine
      D09745  Valsartan - amlodipine besilate mixt
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D09745  Valsartan - amlodipine besilate mixt
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP3A4
   Valsartan and amlodipine
    D09745  Valsartan - amlodipine besilate mixt
Cardiovascular agents [br08364.html]
 Antihypertensives
  D09745
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D09745
BRITE hierarchy
Other DBs
PubChem: 
LinkDB All DBs

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