benzaldehyde dehydrogenase (NAD) [EC:1.2.1.28]

PMID:7868591

Inoue J, Shaw JP, Rekik M, Harayama S

Overlapping substrate specificities of benzaldehyde dehydrogenase (the xylC gene  product) and 2-hydroxymuconic semialdehyde dehydrogenase (the xylG gene product)  encoded by TOL plasmid pWW0 of Pseudomonas putida.

J Bacteriol 177:1196-201 (1995)
DOI:10.1128/JB.177.5.1196-1201.1995

[ag:AAA66218]

4-hydroxybenzaldehyde dehydrogenase (NADP+) [EC:1.2.1.96]

PMID:23736872

Chen YF, Chao H, Zhou NY

The catabolism of 2,4-xylenol and p-cresol share the enzymes for the oxidation of para-methyl group in Pseudomonas putida NCIMB 9866.

Appl Microbiol Biotechnol 98:1349-56 (2014)
DOI:10.1007/s00253-013-5001-z

[ag:AGO01127]

Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor

benzaldehyde:NADP+ oxidoreductase

benzaldehyde + NADP+ + H2O = benzoate + NADPH + 2 H+ [RN:R01420]

R01420;
(other) R01294 R05289 R05663 R05664 R07666

benzaldehyde [CPD:C00261];
NADP+ [CPD:C00006];
H2O [CPD:C00001]

EC 1.2.1.7 created 1961

1  [PMID:13108854]

GUNSALUS CF, STANIER RY, GUNSALUS IC.

The enzymatic conversion of mandelic acid to benzoic acid. III. Fractionation and properties of the soluble enzymes.

J. Bacteriol. 66 (1953) 548-53.

2  [PMID:4383635]

Stachow CS, Stevenson IL, Day D.

Purification and properties of nicotinamide adenine dinucleotide phosphate-specific benzaldehyde dehydrogenase from Pseudomonas.

J. Biol. Chem. 242 (1967) 5294-300.

Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor

4-hydroxybenzaldehyde:NAD+ oxidoreductase

4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + 2 H+ [RN:R01293]

R01293;
(other) R07667

4-hydroxybenzaldehyde [CPD:C00633];
NAD+ [CPD:C00003];
H2O [CPD:C00001]

The bacterial enzyme (characterized from an unidentified denitrifying bacterium) is involved in an anaerobic toluene degradation pathway. The plant enzyme is involved in formation of 4-hydroxybenzoate, a cell wall-bound phenolic acid that plays a major role in plant defense against pathogens. cf. EC 1.2.1.96, 4-hydroxybenzaldehyde dehydrogenase (NADP+).

EC 1.2.1.64 created 2000, modified 2015

1  [PMID:2722739]

Bossert ID, Whited G, Gibson DT, Young LY.

Anaerobic oxidation of p-cresol mediated by a partially purified methylhydroxylase from a denitrifying bacterium.

J. Bacteriol. 171 (1989) 2956-62.

2  [PMID:17658659]

Sircar D, Mitra A

Evidence for p-hydroxybenzoate formation involving enzymatic phenylpropanoid side-chain cleavage in hairy roots of Daucus carota.

J. Plant. Physiol. 165 (2008) 407-14.

Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor

benzaldehyde:NAD+ oxidoreductase

benzaldehyde + NAD+ + H2O = benzoate + NADH + 2 H+ [RN:R01419]

R01419;
(other) R01293 R05289 R05663 R05664 R07667

benzaldehyde [CPD:C00261];
NAD+ [CPD:C00003];
H2O [CPD:C00001]

EC 1.2.1.28 created 1972

1  [PMID:13108854]

GUNSALUS CF, STANIER RY, GUNSALUS IC.

The enzymatic conversion of mandelic acid to benzoic acid. III. Fractionation and properties of the soluble enzymes.

J. Bacteriol. 66 (1953) 548-53.

Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor

4-hydroxybenzaldehyde:NADP+ oxidoreductase

4-hydroxybenzaldehyde + NADP+ + H2O = 4-hydroxybenzoate + NADPH + 2 H+ [RN:R01294]

R01294;
(other) R11195

4-hydroxybenzaldehyde [CPD:C00633];
NADP+ [CPD:C00006];
H2O [CPD:C00001]

Involved in the aerobic pathway for degradation of toluene, 4-methylphenol, and 2,4-xylenol by several Pseudomonas strains. The enzyme is also active with 4-hydroxy-3-methylbenzaldehyde. cf. EC 1.2.1.64, 4-hydroxybenzaldehyde dehydrogenase (NAD+).

EC 1.2.1.96 created 2015

1  [PMID:2019564]

Whited GM, Gibson DT.

Separation and partial characterization of the enzymes of the toluene-4-monooxygenase catabolic pathway in Pseudomonas mendocina KR1.

J. Bacteriol. 173 (1991) 3017-20.

2  [PMID:23736872]

Chen YF, Chao H, Zhou NY

The catabolism of 2,4-xylenol and p-cresol share the enzymes for the oxidation of para-methyl group in Pseudomonas putida NCIMB 9866.

Appl. Microbiol. Biotechnol. 98 (2014) 1349-56.

[ag:AGO01127]