| Entry |
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| Name |
arylamine N-acetyltransferase;
arylamine acetylase;
beta-naphthylamine N-acetyltransferase;
4-aminobiphenyl N-acetyltransferase;
acetyl CoA-arylamine N-acetyltransferase;
2-naphthylamine N-acetyltransferase;
arylamine acetyltransferase;
indoleamine N-acetyltransferase;
N-acetyltransferase (ambiguous);
p-aminosalicylate N-acetyltransferase;
serotonin acetyltransferase;
serotonin N-acetyltransferase
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| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
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| Sysname |
acetyl-CoA:arylamine N-acetyltransferase
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| Reaction(IUBMB) |
acetyl-CoA + an arylamine = CoA + an N-acetylarylamine [RN: R02387]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Wide specificity for aromatic amines, including serotonin; also catalyses acetyl-transfer between arylamines without CoA.
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| History |
EC 2.3.1.5 created 1961
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| Pathway |
| Caffeine metabolism | | Nitrotoluene degradation | | Drug metabolism - other enzymes | | Metabolic pathways | | Biosynthesis of secondary metabolites | | Microbial metabolism in diverse environments |
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| Orthology |
| arylamine N-acetyltransferase |
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| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | NLE: | | MCC: | | MCF: | | CSAB: | | RRO: | | CJC: | | SBQ: | | MMU: | | RNO: | | CGE: | | NGI: | | CCAN: | | OCU: | | TUP: | | AML: | | UMR: | | FCA: | | PTG: | | AJU: | | BTA: | | BOM: | | BIU: | | PHD: | | CHX: | | OAS: | | SSC: | | CFR: | | BACU: | | LVE: | | ECB: | | MYD: | | RSS: | | LAV: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | CJO: | | APLA: | | ACYG: | | TGU: | | GFR: | | FAB: | | PHI: | | CCW: | | FPG: | | FCH: | | CLV: | | AAM: | | ASN: | | AMJ: | | PSS: | | CMY: | | CPIC: | | ACS: | | PBI: | | GJA: | | NPR: | | DRE: | | SRX: | | SANH: | | SGH: | | IPU: | | LCO: | | NCC: | | MZE: | | OLA: | | XMA: | | CSEM: | | LCF: | | SASA: | | ELS: | | SFM: | | CMK: | | BEQ: | | MTU: | | MTV: | | MTC: | | MRA: | | MTF: | | MTB: | | MTK: | | MTZ: | | MTG: | | MTI: | | MTE: | | MTUR: | | MTL: | | MTO: | | MTD: | | MTN: | | MTJ: | | MTUB: | | MTUC: | | MTUE: | | MTX: | | MTUH: | | MTUL: | | MTUT: | | MTUU: | | MTQ: | | MBO: | | MBB: | | MBT: | | MBM: | | MBK: | | MBZ: | | MAF: | | MCE: | | MCQ: | | MCV: | | MCX: | | MCZ: | | MMIC: | | MPA: | | MAO: | | MAVI: | | MAVU: | | MAV: | | MAVD: | | MAVR: | | MAVA: | | MIT: | | MIA: | | MIE: | | MIR: | | MID: | | MYO: | | MCHI: | | MSM: | | MSG: | | MSB: | | MSN: | | MSH: | | MSA: | | MUL: | | MVA: | | MGI: | | MSP: | | MMC: | | MKM: | | MJL: | | MJD: | | MMI: | | MMAE: | | MRH: | | MMM: | | MLI: | | MKN: | | MKS: | | MKI: | | MNE: | | MYV: | | MGO: | | MFT: | | MHAD: | | BLIN: | | PSEA: | | PSEE: | | PSEQ: | | PECQ: | |
» show all
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| Reference |
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| Authors |
CHOU TC, LIPMANN F. |
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| Title |
Separation of acetyl transfer enzymes in pigeon liver extract. |
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| Journal |
J. Biol. Chem. 196 (1952) 89-103. |
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| Reference |
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| Authors |
Paul RC, Ratledge C. |
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| Title |
Further studies on anthranilate N-acetyltransferase and the metabolism of N-acetylanthranilic acid in Aerobacter aerogenes. |
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| Journal |
Biochim. Biophys. Acta. 320 (1973) 9-15. |
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| Reference |
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| Authors |
TABOR H, MEHLER AH, STADTMAN ER. |
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| Title |
The enzymatic acetylation of amines. |
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| Journal |
J. Biol. Chem. 204 (1953) 127-38. |
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| Reference |
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| Authors |
WEISSBACH H, REDFIELD BG, AXELROD J. |
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| Title |
The exzymic acetylation of serotonin and other naturally occurring amines. |
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| Journal |
Biochim. Biophys. Acta. 54 (1961) 190-2. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: UM-BBD (Biocatalysis/Biodegradation Database): BRENDA, the Enzyme Database: CAS: 9027-33-2 |
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| LinkDB |
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