KEGG ORTHOLOGY: K01799

ORTHOLOGY: K01799

Entry

K01799 KO

Name

nicE, maiA

Definition

maleate isomerase [EC:5.2.1.1]

Pathway

ko00650	Butanoate metabolism
ko00760	Nicotinate and nicotinamide metabolism

Module

M00622

Nicotinate degradation, nicotinate => fumarate

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Carbohydrate metabolism
   00650 Butanoate metabolism
    K01799  nicE, maiA; maleate isomerase
  Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K01799  nicE, maiA; maleate isomerase
KEGG modules [BR:ko00002]
Pathway module
  Nucleotide and amino acid metabolism
   Cofactor and vitamin biosynthesis
    M00622  Nicotinate degradation, nicotinate => fumarate
     K01799  nicE, maiA; maleate isomerase
Enzymes [BR:ko01000]
5. Isomerases
  5.2  cis-trans-Isomerases
   5.2.1  cis-trans Isomerases (only sub-subclass identified to date)
    5.2.1.1  maleate isomerase
     K01799  nicE, maiA; maleate isomerase

Other DBs

RN:

R01087

COG:

COG3473

GO:

0050076

Genes

ZJU:	107408901
PFY:	PFICI_01014
PSCO:	LY89DRAFT_618811
GLZ:	GLAREA_08690
PNO:	SNOG_03544
EBT:	EBL_c27830
SPE:	Spro_2309
SRR:	SerAS9_2266
SRL:	SOD_c21390(maiA)
SRY:	M621_11720
SPLY:	Q5A_011855(maiA)
SRS:	SerAS12_2266
SRA:	SerAS13_2267
SMW:	SMWW4_v1c23230
SMAR:	SM39_1768(maiA)
SMAC:	SMDB11_1581(maiA)
SLQ:	M495_11490
SERF:	L085_17130
SOD:	Sant_2212
PAO:	Pat9b_5178
TCI:	A7K98_12080
XDO:	XDD1_0586
XHO:	A9255_13120
PRG:	RB151_005020(maiA)
SNJ:	A7E77_04535
VHA:	VIBHAR_04928
VCA:	M892_26520
VEX:	VEA_000640
VSP:	VS_II0050
VCY:	IX92_17120 IX92_20935
VTU:	IX91_15750
VMI:	AL543_14585
PCQ:	PcP3B5_31700
PPU:	PP_3942(nicE)
PPF:	Pput_1895
PPG:	PputGB1_3577
PPW:	PputW619_2142
PPT:	PPS_4060
PPB:	PPUBIRD1_1866
PPI:	YSA_08971
PPX:	T1E_5125
PPUT:	L483_16805 L483_21700
PPUN:	PP4_17800
PMON:	X969_19890
PMOT:	X970_19525
PFS:	PFLU_2797
PFE:	PSF113_3457
PFN:	HZ99_03120 HZ99_07180
PFW:	PF1751_v1c24680
PFB:	VO64_0124
PFF:	PFLUOLIPICF724390
PFX:	A7318_11840
PAZO:	AYR47_21605
PSTT:	CH92_09510
PSK:	U771_14845
PCZ:	PCL1606_46840
PFZ:	AV641_08715
PANR:	A7J50_2714
PSPG:	AK823_05280
ACV:	AMD27_12435
SPL:	Spea_4076
SHL:	Shal_0169
SWD:	Swoo_0109
CPS:	CPS_4918
COLW:	A3Q33_05515
MBS:	MRBBS_2286 MRBBS_2436
MSX:	AU14_10535
MPQ:	ABA45_18020
MSQ:	BKP64_09135
PIN:	Ping_3672
OSG:	BST96_04605 BST96_11010 BST96_13805 BST96_17350 BST96_17360
MICC:	AUP74_02921(maiA_1) AUP74_02923(maiA_2)
MAGA:	Mag101_09835 Mag101_09845
HAM:	HALO0541
HHU:	AR456_15770 AR456_15795
HCO:	LOKO_00400
HALO:	BWR19_16215
ADI:	B5T_02294
MARS:	A8C75_16310 A8C75_17750
OCE:	GU3_08030 GU3_08375
SDF:	ACG33_07670
TSN:	W908_02355
RSO:	RSc1822
RSM:	CMR15_11829
RSE:	F504_1567
RPI:	Rpic_1881 Rpic_4021
RPF:	Rpic12D_1552 Rpic12D_4134
RPJ:	N234_00215 N234_03080 N234_04320 N234_09685 N234_23140 N234_24880
REU:	Reut_A0046 Reut_A2514 Reut_B3786 Reut_B5483
REH:	H16_A0069(h16_A0069) H16_A0923(h16_A0923) H16_B0811(h16_B0811)
CNC:	CNE_1c00660 CNE_1c08730 CNE_2c07590 CNE_2c20830
RME:	Rmet_3781 Rmet_3887
CTI:	RALTA_A0028 RALTA_A0868 RALTA_B0115
CBW:	RR42_m0068 RR42_s0169 RR42_s1170
CGD:	CR3_3009(nicE)
CCUP:	BKK81_02760 BKK81_07360 BKK81_20440
BUR:	Bcep18194_B0631 Bcep18194_B3099
BCN:	Bcen_4325 Bcen_6407
BCH:	Bcen2424_4041 Bcen2424_6640
BCM:	Bcenmc03_3484 Bcenmc03_6238
BCJ:	BCAL1155 BCAM1144 BCAM2273
BCEN:	DM39_3877 DM39_4153 DM39_5064 DM39_6462
BCEO:	I35_4991 I35_6166
BAM:	Bamb_3395
BMU:	Bmul_4548
BMK:	DM80_3718
BMUL:	NP80_4071
BCT:	GEM_5631
BCED:	DM42_3946 DM42_5718
BPYR:	ABD05_31610
BCON:	NL30_06910
BDF:	WI26_26465
BSEM:	WJ12_16050 WJ12_25620
BPSL:	WS57_00360 WS57_08405 WS57_17180
BMEC:	WJ16_24250 WJ16_29700
BSTG:	WT74_17090 WT74_20835
BGP:	BGL_1c11620 BGL_1c25290 BGL_1c33240
BGE:	BC1002_4833 BC1002_6021
BGF:	BC1003_4456
BGD:	bgla_1g12690 bgla_4p3100
BGO:	BM43_2601
BYI:	BYI23_A013540 BYI23_A013600 BYI23_C007500 BYI23_D005170 BYI23_D006300 BYI23_D011180
BUO:	BRPE64_CCDS07110 BRPE64_DCDS05920 BRPE64_DCDS10970
BUE:	BRPE67_ACDS13960 BRPE67_ACDS14020 BRPE67_CCDS03910 BRPE67_DCDS06970 BRPE67_DCDS08120 BRPE67_DCDS13290
BPLA:	bpln_1g11140 bpln_1g24840 bpln_1g32240
BXE:	Bxe_C0068 Bxe_C0214 Bxe_C0733
BXB:	DR64_7687 DR64_8217 DR64_8357(eutA)
BPH:	Bphy_4991 Bphy_7794
BPX:	BUPH_01859 BUPH_08281 BUPH_08322 BUPH_08405
BPY:	Bphyt_7135
BFN:	OI25_318 OI25_3921(eutA) OI25_5600 OI25_6801
BCAI:	K788_0007379
PSPW:	BJG93_20140 BJG93_22520 BJG93_29590
PPK:	U875_05240 U875_07765 U875_16870
PPNO:	DA70_00460 DA70_08940 DA70_22310
PPNM:	LV28_05855 LV28_21870
PRB:	X636_01870 X636_17550
PPUL:	RO07_24805
PSPU:	NA29_11650 NA29_13045
PAPI:	SG18_23385
PVE:	UC34_07155 UC34_12650
POX:	MB84_19955 MB84_21130
PTX:	ABW99_04230 ABW99_15290
PNR:	AT302_16710 AT302_19820 AT302_20385
BPE:	BP0579(maiA) BP1955(maiA)
BPC:	BPTD_0588(maiA) BPTD_1927(maiA)
BPER:	BN118_0959(maiA) BN118_3488(maiA)
BPET:	B1917_3475(maiA)
BPEU:	Q425_15010(maiA) Q425_35700(maiA)
BPA:	BPP0573
BPAR:	BN117_0267(maiA) BN117_1482
BBR:	BB0272(maiA) BB0579 BB1779(maiA)
BBM:	BN115_0257(maiA) BN115_0552 BN115_1681(maiA)
BBH:	BN112_1736(maiA) BN112_2860 BN112_3145(maiA)
BBX:	BBS798_0267(maiA) BBS798_0553 BBS798_1680(maiA)
BAV:	BAV1531(maiA1) BAV2744(maiA2)
BHZ:	ACR54_00881(maiA) ACR54_01158
BTRM:	SAMEA390648701697
BBRO:	BAU06_05785 BAU06_12285 BAU06_13160 BAU06_21410 BAU06_25025
BFZ:	BAU07_03715 BAU07_10525 BAU07_14050 BAU07_14200 BAU07_25060
AXY:	AXYL_00363 AXYL_01289 AXYL_05784
AXO:	NH44784_018121
AXN:	AX27061_0393
AXS:	LH59_01945
AXX:	ERS451415_00390
ADT:	APT56_02100
AIS:	BUW96_19820 BUW96_27610 BUW96_29270
PUT:	PT7_2991
AKA:	TKWG_00715 TKWG_22115
AMIM:	MIM_c01620
AFA:	UZ73_12950
PHN:	PAEH1_07355
RHY:	RD110_00345 RD110_17950 RD110_19120
POL:	Bpro_0550 Bpro_2119
AAV:	Aave_3928
AAA:	Acav_3338 Acav_3825
ACK:	C380_17095
VEI:	Veis_4205
DAC:	Daci_1852
DEL:	DelCs14_4786 DelCs14_5221
DTS:	BI380_15390 BI380_18155
DHK:	BO996_06600 BO996_08770
VAP:	Vapar_0652 Vapar_4278
VPD:	VAPA_1c01240 VAPA_1c07140 VAPA_2c00650
CTT:	CtCNB1_2933
CTES:	O987_17735 O987_23180
ADN:	Alide_1002 Alide_2434
ADK:	Alide2_2612
RTA:	Rta_32550
HAR:	HEAR1463(maiA)
HSE:	Hsero_1323
HSZ:	ACP92_06620
HHT:	F506_04090
HRB:	Hrubri_3732 Hrubri_4423
PBH:	AAW51_5193(nicE)
AZA:	AZKH_1740
LLU:	AKJ09_02929
SFU:	Sfum_3580
MLO:	mlr7137
MLN:	A9174_29940 A9174_31380 A9174_33975
MCI:	Mesci_2504 Mesci_4174
MOP:	Mesop_5924
MAM:	Mesau_05396
MAMO:	A6B35_03985 A6B35_24270
MESW:	A9K65_013095 A9K65_023180
HOE:	IMCC20628_03275 IMCC20628_03535 IMCC20628_03689
AAK:	AA2016_1147 AA2016_5867 AA2016_6582
SME:	SM_b20431
SMK:	Sinme_3749 Sinme_6483 Sinme_6720
SMQ:	SinmeB_4245
SMX:	SM11_pC0455 SM11_pD1191(eutA)
SMI:	BN406_04914 BN406_06243
SMEG:	C770_GR4pD1180
SMEL:	SM2011_b20431(eutA)
SMER:	DU99_20155 DU99_31155
SMD:	Smed_3696
RHI:	NGR_b23280
SFH:	SFHH103_04915
SFD:	USDA257_c31360
SIX:	BSY16_5547(eutA)
SAME:	SAMCFNEI73_pC1838
EAD:	OV14_b1413
EAH:	FA04_31155
ARA:	Arad_7303 Arad_8559
ATF:	Ach5_50180
ATA:	AWN88_01330
AVI:	Avi_7410
RET:	RHE_PF00183
REC:	RHECIAT_PC0000377
REL:	REMIM1_PF00733(eutA)
REI:	IE4771_PD00203(eutA)
REP:	IE4803_PC00202(eutA)
RLE:	pRL100067 pRL120051
RLT:	Rleg2_5518
RLG:	Rleg_5239 Rleg_6044
RLB:	RLEG3_09325
RLU:	RLEG12_04760
RTR:	RTCIAT899_PC00225 RTCIAT899_PC08590
RHL:	LPU83_pLPU83d1321
RGA:	RGR602_PC02178(eutA)
RHN:	AMJ98_PE00277(eutA)
RPHA:	AMC79_PD00410(eutA)
RHX:	AMK02_PD00143(eutA)
NGL:	RG1141_PA13070
NGG:	RG540_PA14050
SHZ:	shn_23115 shn_29345 shn_30295
BJA:	blr3294
BJU:	BJ6T_64700
BJP:	RN69_31360
BRA:	BRADO1491
BBT:	BBta_6543
BRS:	S23_47110
AOL:	S58_17210
BRAD:	BF49_1338
BOP:	AXW83_14115 AXW83_21260
BVV:	BHK69_28365
AZC:	AZC_4372
SNO:	Snov_2859 Snov_3617
MRD:	Mrad2831_1246
MET:	M446_0462
MNO:	Mnod_0887 Mnod_7935
MOR:	MOC_1470
MAQU:	Maq22A_1p34105 Maq22A_c00990
CHEL:	AL346_04860
HMC:	HYPMC_0201(maiA)
PHL:	KKY_3786
DEQ:	XM25_21590
RHZ:	RHPLAN_06850 RHPLAN_26800 RHPLAN_51240 RHPLAN_51300 RHPLAN_54290 RHPLAN_55030 RHPLAN_55540 RHPLAN_55970 RHPLAN_58420 RHPLAN_68880
MEY:	TM49_06800
MMED:	Mame_02827
PSIN:	CAK95_04900 CAK95_12365
RBM:	TEF_13085
CAK:	Caul_0501
BNE:	DA69_03075
SIL:	SPOA0117
SIT:	TM1040_2711
RMB:	K529_013255
RSQ:	Rsph17025_3174
JAN:	Jann_1830 Jann_3773
RDE:	RD1_3471
RLI:	RLO149_c026680
PDE:	Pden_0284 Pden_4618
PYE:	A6J80_00010 A6J80_20870 A6J80_21880 A6J80_23210
DSH:	Dshi_1038
PSF:	PSE_1837
PGA:	PGA1_c21150
PGL:	PGA2_c20000
PGD:	Gal_01287
PHP:	PhaeoP97_01851
OAT:	OAN307_c42120
OAR:	OA238_c03510 OA238_c08150 OA238_c23640(eutA)
OTM:	OSB_12060
LMD:	METH_15515 METH_17325 METH_21510
RED:	roselon_00784
PTP:	RCA23_c18870 RCA23_c26640
CID:	P73_2834 P73_2839 P73_2973 P73_3894
MALG:	MALG_00800 MALG_04113
CON:	TQ29_09630 TQ29_11645 TQ29_12580 TQ29_12780
PPHR:	APZ00_25420
HAT:	RC74_18020
LAP:	ACP90_02915
LAGG:	B0E33_14395
DAA:	AKL17_0189
YAN:	AYJ57_01660 AYJ57_24125
SUAM:	BOO69_15110
DON:	BSK21_09015
TPRO:	Ga0080559_TMP4590 Ga0080559_TMP4915
TOM:	BWR18_00750
PABY:	Ga0080574_TMP1163 Ga0080574_TMP2108 Ga0080574_TMP33 Ga0080574_TMP5150 Ga0080574_TMP529
THW:	BMG03_02485
RMM:	ROSMUCSMR3_00340
LVS:	LOKVESSMR4R_00384 LOKVESSMR4R_03234(maiA)
NPP:	PP1Y_AT10593
NRE:	BES08_21935 BES08_22490
SAL:	Sala_1385
SPHK:	SKP52_06960(maiA)
SMAG:	AN936_11245
SMAZ:	LH19_12395
SGI:	SGRAN_2937(maiA2)
SWI:	Swit_0831
STAX:	MC45_16570
SPHI:	TS85_14895
SSAN:	NX02_13760
SPHG:	AZE99_12455
BLAS:	BSY18_2910
ELQ:	Ga0102493_113020
ADO:	A6F68_02581(maiA)
GXL:	H845_1040
KEU:	S101446_01674(nicE)
APT:	APA01_23730
APW:	APA42C_23730
APF:	APA03_23730
APU:	APA07_23730
APG:	APA12_23730
APQ:	APA22_23730
APX:	APA26_23730
APZ:	APA32_23730
APK:	APA386B_1207(maiA)
ASV:	WG31_11890
ALI:	AZOLI_p20260 AZOLI_p20437
ABS:	AZOBR_p210125 AZOBR_p480009
ABQ:	ABAZ39_23985 ABAZ39_30190
ABF:	AMK58_22180 AMK58_25915
ATI:	AL072_17670 AL072_27300 AL072_30675
TMO:	TMO_a0282 TMO_a0378 TMO_b0386
TXI:	TH3_02605
PUB:	SAR11_1339
APM:	HIMB5_00009780
APB:	SAR116_0770
PBJ:	VN24_09505
BTS:	Btus_2321
AMT:	Amet_1195
DSY:	DSY0374
DHD:	Dhaf_0302
DDH:	Desde_0317
MSM:	MSMEG_1319 MSMEG_2495 MSMEG_3993 MSMEG_4610
MSG:	MSMEI_1282 MSMEI_2435 MSMEI_3900 MSMEI_4492
MSB:	LJ00_06575 LJ00_12420 LJ00_19835 LJ00_22800
MSN:	LI99_06575 LI99_12420 LI99_19840 LI99_22805
MSH:	LI98_06575 LI98_12425 LI98_19845 LI98_22810
MAB:	MAB_4413c
MABB:	MASS_4450
MMV:	MYCMA_04045
MAY:	LA62_22405
MABO:	NF82_22095
MABL:	MMASJCM_4474
MAZ:	LA61_22300
MAK:	LH56_02270
MYS:	NF92_02320
MYC:	NF90_02320
MCHE:	BB28_22605
MIZ:	BAB75_25065
MJD:	JDM601_2704
MMI:	MMAR_3401
MMAE:	MMARE11_33041
MLI:	MULP_03664
MGO:	AFA91_20420
MPHL:	MPHLCCUG_04301(maiA)
MVQ:	MYVA_2930(maiA)
ASD:	AS9A_3597
NFA:	NFA_21930
NFR:	ERS450000_01905
NCY:	NOCYR_3767
NBR:	O3I_030465
NNO:	NONO_c51200(maiA) NONO_c54880
NSL:	BOX37_12645
RHA:	RHA1_ro00478 RHA1_ro04577
ROP:	ROP_34370(maiA) ROP_44900
ROA:	Pd630_LPD01047 Pd630_LPD03771 Pd630_LPD04577 Pd630_LPD07333
RPY:	Y013_19070
RHB:	NY08_2121
RHW:	BFN03_15150
GBR:	Gbro_4096
GOR:	KTR9_4024
GOQ:	ACH46_09950
GTA:	BCM27_21140 BCM27_25005
SCO:	SCO2823(SCBAC17F8.14c)
SMA:	SAV_5234
SGR:	SGR_354
SGB:	WQO_24580
SVL:	Strvi_4758 Strvi_8170
SCT:	SCAT_2832 SCAT_5468
SCY:	SCATT_28210 SCATT_54680
SBH:	SBI_06829 SBI_08672
SVE:	SVEN_5449
SDV:	BN159_5448
SALB:	XNR_1727
SALS:	SLNWT_2382 SLNWT_4228
SCI:	B446_14860
SRC:	M271_30770 M271_44540
SALU:	DC74_1461 DC74_3288
SALL:	SAZ_07830 SAZ_17520
SLV:	SLIV_23550
SVT:	SVTN_24815 SVTN_27915
STRE:	GZL_05617
SLD:	T261_5273
SXI:	SXIM_39380
STRC:	AA958_10555
SAMB:	SAM23877_2871
SPRI:	SPRI_4712 SPRI_6098
SCZ:	ABE83_19125 ABE83_19765
SCX:	AS200_28270
SRW:	TUE45_06907(maiA)
STRF:	ASR50_13710
SPAV:	Spa2297_12055
SLC:	SL103_05215
SGS:	AVL59_41800
STSI:	A4E84_14900
SLS:	SLINC_3242
SNR:	SNOUR_26265
SPLU:	LK06_010900
STRD:	NI25_24670
ART:	Arth_4067
ARI:	UM93_06555
ARE:	AL755_04310
AAQ:	AOC05_00975
ARH:	AHiyo8_24660 AHiyo8_24670 AHiyo8_36510
ARZ:	AUT26_18910 AUT26_19440
APN:	Asphe3_10480
RSA:	RSal33209_1838(igiC)
KFV:	AS188_01335 AS188_10275
SATK:	SA2016_3806 SA2016_3969
LMOI:	VV02_11305
SERJ:	SGUI_0401
JTE:	ASJ30_15250
PBO:	PACID_31330
PSIM:	KR76_02240
NDA:	Ndas_4753
NAL:	B005_2082
SRO:	Sros_6615
NOA:	BKM31_58615
FRE:	Franean1_3132 Franean1_3716
FRI:	FraEuI1c_3142 FraEuI1c_4424
ACE:	Acel_1639
GOB:	Gobs_1250
MMAR:	MODMU_3889
SEN:	SACE_1839 SACE_4875
SVI:	Svir_30140
AMD:	AMED_7872
AMN:	RAM_40455
AMM:	AMES_7754
AMZ:	B737_7754
AOI:	AORI_4775 AORI_5999 AORI_6705
AJA:	AJAP_05595 AJAP_09440 AJAP_15765(maiA)
AMQ:	AMETH_0217 AMETH_1088 AMETH_2130 AMETH_3950 AMETH_5705
ALU:	BB31_11025 BB31_23880
PDX:	Psed_1036 Psed_4251 Psed_6340
PSEE:	FRP1_17285 FRP1_20585
PSEH:	XF36_05320
PSEQ:	AD006_24740 AD006_28005
PECQ:	AD017_04330 AD017_07600
PHH:	AFB00_17855
SESP:	BN6_40600
AHM:	TL08_10970
ACTI:	UA75_11710 UA75_21005 UA75_24025
ACAD:	UA74_11625 UA74_20510 UA74_23515
ALL:	CRK58853
VMA:	VAB18032_20605
AMS:	AMIS_5020 AMIS_57320
SNA:	Snas_1911
CWO:	Cwoe_3972
GLP:	Glo7428_4235
NON:	NOS3756_48200
AVA:	Ava_4999
NAZ:	Aazo_2601
IPO:	Ilyop_0101
ACO:	Amico_0502
GBA:	J421_5247
HHY:	Halhy_5099
FPSZ:	AMR72_01615
FIN:	KQS_01655
HJE:	HacjB3_12310
HALI:	BV210_07840
HBO:	Hbor_32410
HTU:	Htur_3570
NAT:	NJ7G_2903
NPE:	Natpe_0253
NGE:	Natgr_2292
NOU:	Natoc_2438
HLR:	HALLA_01715 HALLA_10245
FAC:	FACI_IFERC01G0816
FAI:	FAD_1707
PHO:	PH0985(PH0985) PH1150(PH1150)
PAB:	PAB2420
PFU:	PF1344
PFI:	PFC_05935
PYN:	PNA2_1775
PYA:	PYCH_07690
PYS:	Py04_0947
PYC:	TQ32_06050
TKO:	TK0375
TON:	TON_1011
TGA:	TGAM_1479(maiA)
TSI:	TSIB_1221
TBA:	TERMP_01161
THE:	GQS_10405
THA:	TAM4_1581
THM:	CL1_1658
TLT:	OCC_01039
THS:	TES1_1219
TNU:	BD01_1046
TEU:	TEU_11115
TGY:	X802_00250 X802_09605
THV:	ADU37_CDS09460
TCH:	CHITON_1459
TPEP:	A0127_02445
PPAC:	PAP_04900
APE:	APE_2520.1(maiA)
SSO:	SSO2939(maiA)
SOL:	Ssol_0732
SSOA:	SULA_0726
SSOL:	SULB_0728
SSOF:	SULC_0726
STO:	STK_06560 STK_06670
SULA:	BFU36_12570
MCN:	Mcup_0967
AHO:	Ahos_0996 Ahos_2039
AMAN:	B6F84_01570 B6F84_04585 B6F84_09145
CMA:	Cmaq_1394
VDI:	Vdis_0556
ASC:	ASAC_1406
CSU:	CSUB_C1702
BARC:	AOA65_1124(maiA)

» show all

Reference

PMID:18678916

Authors

Jimenez JI, Canales A, Jimenez-Barbero J, Ginalski K, Rychlewski L, Garcia JL, Diaz E

Title

Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440.

Journal

Proc Natl Acad Sci U S A 105:11329-34 (2008)
DOI:10.1073/pnas.0802273105

LinkDB

ENZYME: 5.2.1.1

Entry

EC 5.2.1.1 Enzyme

Name

maleate isomerase

Class

Isomerases;
cis-trans-Isomerases;
cis-trans Isomerases (only sub-subclass identified to date)

Sysname

maleate cis-trans-isomerase

Reaction(IUBMB)

maleate = fumarate [RN:R01087]

Reaction(KEGG)

R01087

Substrate

maleate [CPD:C01384]

Product

fumarate [CPD:C00122]

History

EC 5.2.1.1 created 1961

Pathway

ec00650	Butanoate metabolism
ec00760	Nicotinate and nicotinamide metabolism
ec01120	Microbial metabolism in diverse environments

Orthology

K01799

maleate isomerase

Genes

ZJU:	107408901
PFY:	PFICI_01014
PSCO:	LY89DRAFT_618811
GLZ:	GLAREA_08690
PNO:	SNOG_03544
EBT:	EBL_c27830
SPE:	Spro_2309
SRR:	SerAS9_2266
SRL:	SOD_c21390(maiA)
SRY:	M621_11720
SPLY:	Q5A_011855(maiA)
SRS:	SerAS12_2266
SRA:	SerAS13_2267
SMW:	SMWW4_v1c23230
SMAR:	SM39_1768(maiA)
SMAC:	SMDB11_1581(maiA)
SLQ:	M495_11490
SERF:	L085_17130
SOD:	Sant_2212
PAO:	Pat9b_5178
TCI:	A7K98_12080
XDO:	XDD1_0586
XHO:	A9255_13120
PRG:	RB151_005020(maiA)
SNJ:	A7E77_04535
VHA:	VIBHAR_04928
VCA:	M892_26520
VEX:	VEA_000640
VSP:	VS_II0050
VCY:	IX92_17120 IX92_20935
VTU:	IX91_15750
VMI:	AL543_14585
PCQ:	PcP3B5_31700
PPU:	PP_3942(nicE)
PPF:	Pput_1895
PPG:	PputGB1_3577
PPW:	PputW619_2142
PPT:	PPS_4060
PPB:	PPUBIRD1_1866
PPI:	YSA_08971
PPX:	T1E_5125
PPUT:	L483_16805 L483_21700
PPUN:	PP4_17800
PMON:	X969_19890
PMOT:	X970_19525
PFS:	PFLU_2797
PFE:	PSF113_3457
PFN:	HZ99_03120 HZ99_07180
PFW:	PF1751_v1c24680
PFB:	VO64_0124
PFF:	PFLUOLIPICF724390
PFX:	A7318_11840
PAZO:	AYR47_21605
PSTT:	CH92_09510
PSK:	U771_14845
PCZ:	PCL1606_46840
PFZ:	AV641_08715
PANR:	A7J50_2714
PSPG:	AK823_05280
ACV:	AMD27_12435
SPL:	Spea_4076
SHL:	Shal_0169
SWD:	Swoo_0109
CPS:	CPS_4918
COLW:	A3Q33_05515
MBS:	MRBBS_2286 MRBBS_2436
MSX:	AU14_10535
MPQ:	ABA45_18020
MSQ:	BKP64_09135
PIN:	Ping_3672
OSG:	BST96_04605 BST96_11010 BST96_13805 BST96_17350 BST96_17360
MICC:	AUP74_02921(maiA_1) AUP74_02923(maiA_2)
MAGA:	Mag101_09835 Mag101_09845
HAM:	HALO0541
HHU:	AR456_15770 AR456_15795
HCO:	LOKO_00400
HALO:	BWR19_16215
ADI:	B5T_02294
MARS:	A8C75_16310 A8C75_17750
OCE:	GU3_08030 GU3_08375
SDF:	ACG33_07670
TSN:	W908_02355
RSO:	RSc1822
RSM:	CMR15_11829
RSE:	F504_1567
RPI:	Rpic_1881 Rpic_4021
RPF:	Rpic12D_1552 Rpic12D_4134
RPJ:	N234_00215 N234_03080 N234_04320 N234_09685 N234_23140 N234_24880
REU:	Reut_A0046 Reut_A2514 Reut_B3786 Reut_B5483
REH:	H16_A0069(h16_A0069) H16_A0923(h16_A0923) H16_B0811(h16_B0811)
CNC:	CNE_1c00660 CNE_1c08730 CNE_2c07590 CNE_2c20830
RME:	Rmet_3781 Rmet_3887
CTI:	RALTA_A0028 RALTA_A0868 RALTA_B0115
CBW:	RR42_m0068 RR42_s0169 RR42_s1170
CGD:	CR3_3009(nicE)
CCUP:	BKK81_02760 BKK81_07360 BKK81_20440
BUR:	Bcep18194_B0631 Bcep18194_B3099
BCN:	Bcen_4325 Bcen_6407
BCH:	Bcen2424_4041 Bcen2424_6640
BCM:	Bcenmc03_3484 Bcenmc03_6238
BCJ:	BCAL1155 BCAM1144 BCAM2273
BCEN:	DM39_3877 DM39_4153 DM39_5064 DM39_6462
BCEO:	I35_4991 I35_6166
BAM:	Bamb_3395
BMU:	Bmul_4548
BMK:	DM80_3718
BMUL:	NP80_4071
BCT:	GEM_5631
BCED:	DM42_3946 DM42_5718
BPYR:	ABD05_31610
BCON:	NL30_06910
BDF:	WI26_26465
BSEM:	WJ12_16050 WJ12_25620
BPSL:	WS57_00360 WS57_08405 WS57_17180
BMEC:	WJ16_24250 WJ16_29700
BSTG:	WT74_17090 WT74_20835
BGP:	BGL_1c11620 BGL_1c25290 BGL_1c33240
BGE:	BC1002_4833 BC1002_6021
BGF:	BC1003_4456
BGD:	bgla_1g12690 bgla_4p3100
BGO:	BM43_2601
BYI:	BYI23_A013540 BYI23_A013600 BYI23_C007500 BYI23_D005170 BYI23_D006300 BYI23_D011180
BUO:	BRPE64_CCDS07110 BRPE64_DCDS05920 BRPE64_DCDS10970
BUE:	BRPE67_ACDS13960 BRPE67_ACDS14020 BRPE67_CCDS03910 BRPE67_DCDS06970 BRPE67_DCDS08120 BRPE67_DCDS13290
BPLA:	bpln_1g11140 bpln_1g24840 bpln_1g32240
BXE:	Bxe_C0068 Bxe_C0214 Bxe_C0733
BXB:	DR64_7687 DR64_8217 DR64_8357(eutA)
BPH:	Bphy_4991 Bphy_7794
BPX:	BUPH_01859 BUPH_08281 BUPH_08322 BUPH_08405
BPY:	Bphyt_7135
BFN:	OI25_318 OI25_3921(eutA) OI25_5600 OI25_6801
BCAI:	K788_0007379
PSPW:	BJG93_20140 BJG93_22520 BJG93_29590
PPK:	U875_05240 U875_07765 U875_16870
PPNO:	DA70_00460 DA70_08940 DA70_22310
PPNM:	LV28_05855 LV28_21870
PRB:	X636_01870 X636_17550
PPUL:	RO07_24805
PSPU:	NA29_11650 NA29_13045
PAPI:	SG18_23385
PVE:	UC34_07155 UC34_12650
POX:	MB84_19955 MB84_21130
PTX:	ABW99_04230 ABW99_15290
PNR:	AT302_16710 AT302_19820 AT302_20385
BPE:	BP0579(maiA) BP1955(maiA)
BPC:	BPTD_0588(maiA) BPTD_1927(maiA)
BPER:	BN118_0959(maiA) BN118_3488(maiA)
BPET:	B1917_3475(maiA)
BPEU:	Q425_15010(maiA) Q425_35700(maiA)
BPA:	BPP0573
BPAR:	BN117_0267(maiA) BN117_1482
BBR:	BB0272(maiA) BB0579 BB1779(maiA)
BBM:	BN115_0257(maiA) BN115_0552 BN115_1681(maiA)
BBH:	BN112_1736(maiA) BN112_2860 BN112_3145(maiA)
BBX:	BBS798_0267(maiA) BBS798_0553 BBS798_1680(maiA)
BAV:	BAV1531(maiA1) BAV2744(maiA2)
BHZ:	ACR54_00881(maiA) ACR54_01158
BTRM:	SAMEA390648701697
BBRO:	BAU06_05785 BAU06_12285 BAU06_13160 BAU06_21410 BAU06_25025
BFZ:	BAU07_03715 BAU07_10525 BAU07_14050 BAU07_14200 BAU07_25060
AXY:	AXYL_00363 AXYL_01289 AXYL_05784
AXO:	NH44784_018121
AXN:	AX27061_0393
AXS:	LH59_01945
AXX:	ERS451415_00390
ADT:	APT56_02100
AIS:	BUW96_19820 BUW96_27610 BUW96_29270
PUT:	PT7_2991
AKA:	TKWG_00715 TKWG_22115
AMIM:	MIM_c01620
AFA:	UZ73_12950
PHN:	PAEH1_07355
RHY:	RD110_00345 RD110_17950 RD110_19120
POL:	Bpro_0550 Bpro_2119
AAV:	Aave_3928
AAA:	Acav_3338 Acav_3825
ACK:	C380_17095
VEI:	Veis_4205
DAC:	Daci_1852
DEL:	DelCs14_4786 DelCs14_5221
DTS:	BI380_15390 BI380_18155
DHK:	BO996_06600 BO996_08770
VAP:	Vapar_0652 Vapar_4278
VPD:	VAPA_1c01240 VAPA_1c07140 VAPA_2c00650
CTT:	CtCNB1_2933
CTES:	O987_17735 O987_23180
ADN:	Alide_1002 Alide_2434
ADK:	Alide2_2612
RTA:	Rta_32550
HAR:	HEAR1463(maiA)
HSE:	Hsero_1323
HSZ:	ACP92_06620
HHT:	F506_04090
HRB:	Hrubri_3732 Hrubri_4423
PBH:	AAW51_5193(nicE)
AZA:	AZKH_1740
LLU:	AKJ09_02929
SFU:	Sfum_3580
MLO:	mlr7137
MLN:	A9174_29940 A9174_31380 A9174_33975
MCI:	Mesci_2504 Mesci_4174
MOP:	Mesop_5924
MAM:	Mesau_05396
MAMO:	A6B35_03985 A6B35_24270
MESW:	A9K65_013095 A9K65_023180
HOE:	IMCC20628_03275 IMCC20628_03535 IMCC20628_03689
AAK:	AA2016_1147 AA2016_5867 AA2016_6582
SME:	SM_b20431
SMK:	Sinme_3749 Sinme_6483 Sinme_6720
SMQ:	SinmeB_4245
SMX:	SM11_pC0455 SM11_pD1191(eutA)
SMI:	BN406_04914 BN406_06243
SMEG:	C770_GR4pD1180
SMEL:	SM2011_b20431(eutA)
SMER:	DU99_20155 DU99_31155
SMD:	Smed_3696
RHI:	NGR_b23280
SFH:	SFHH103_04915
SFD:	USDA257_c31360
SIX:	BSY16_5547(eutA)
SAME:	SAMCFNEI73_pC1838
EAD:	OV14_b1413
EAH:	FA04_31155
ARA:	Arad_7303 Arad_8559
ATF:	Ach5_50180
ATA:	AWN88_01330
AVI:	Avi_7410
RET:	RHE_PF00183
REC:	RHECIAT_PC0000377
REL:	REMIM1_PF00733(eutA)
REI:	IE4771_PD00203(eutA)
REP:	IE4803_PC00202(eutA)
RLE:	pRL100067 pRL120051
RLT:	Rleg2_5518
RLG:	Rleg_5239 Rleg_6044
RLB:	RLEG3_09325
RLU:	RLEG12_04760
RTR:	RTCIAT899_PC00225 RTCIAT899_PC08590
RHL:	LPU83_pLPU83d1321
RGA:	RGR602_PC02178(eutA)
RHN:	AMJ98_PE00277(eutA)
RPHA:	AMC79_PD00410(eutA)
RHX:	AMK02_PD00143(eutA)
NGL:	RG1141_PA13070
NGG:	RG540_PA14050
SHZ:	shn_23115 shn_29345 shn_30295
BJA:	blr3294
BJU:	BJ6T_64700
BJP:	RN69_31360
BRA:	BRADO1491
BBT:	BBta_6543
BRS:	S23_47110
AOL:	S58_17210
BRAD:	BF49_1338
BOP:	AXW83_14115 AXW83_21260
BVV:	BHK69_28365
AZC:	AZC_4372
SNO:	Snov_2859 Snov_3617
MRD:	Mrad2831_1246
MET:	M446_0462
MNO:	Mnod_0887 Mnod_7935
MOR:	MOC_1470
MAQU:	Maq22A_1p34105 Maq22A_c00990
CHEL:	AL346_04860
HMC:	HYPMC_0201(maiA)
PHL:	KKY_3786
DEQ:	XM25_21590
RHZ:	RHPLAN_06850 RHPLAN_26800 RHPLAN_51240 RHPLAN_51300 RHPLAN_54290 RHPLAN_55030 RHPLAN_55540 RHPLAN_55970 RHPLAN_58420 RHPLAN_68880
MEY:	TM49_06800
MMED:	Mame_02827
PSIN:	CAK95_04900 CAK95_12365
RBM:	TEF_13085
CAK:	Caul_0501
BNE:	DA69_03075
SIL:	SPOA0117
SIT:	TM1040_2711
RMB:	K529_013255
RSQ:	Rsph17025_3174
JAN:	Jann_1830 Jann_3773
RDE:	RD1_3471
RLI:	RLO149_c026680
PDE:	Pden_0284 Pden_4618
PYE:	A6J80_00010 A6J80_20870 A6J80_21880 A6J80_23210
DSH:	Dshi_1038
PSF:	PSE_1837
PGA:	PGA1_c21150
PGL:	PGA2_c20000
PGD:	Gal_01287
PHP:	PhaeoP97_01851
OAT:	OAN307_c42120
OAR:	OA238_c03510 OA238_c08150 OA238_c23640(eutA)
OTM:	OSB_12060
LMD:	METH_15515 METH_17325 METH_21510
RED:	roselon_00784
PTP:	RCA23_c18870 RCA23_c26640
CID:	P73_2834 P73_2839 P73_2973 P73_3894
MALG:	MALG_00800 MALG_04113
CON:	TQ29_09630 TQ29_11645 TQ29_12580 TQ29_12780
PPHR:	APZ00_25420
HAT:	RC74_18020
LAP:	ACP90_02915
LAGG:	B0E33_14395
DAA:	AKL17_0189
YAN:	AYJ57_01660 AYJ57_24125
SUAM:	BOO69_15110
DON:	BSK21_09015
TPRO:	Ga0080559_TMP4590 Ga0080559_TMP4915
TOM:	BWR18_00750
PABY:	Ga0080574_TMP1163 Ga0080574_TMP2108 Ga0080574_TMP33 Ga0080574_TMP5150 Ga0080574_TMP529
THW:	BMG03_02485
RMM:	ROSMUCSMR3_00340
LVS:	LOKVESSMR4R_00384 LOKVESSMR4R_03234(maiA)
NPP:	PP1Y_AT10593
NRE:	BES08_21935 BES08_22490
SAL:	Sala_1385
SPHK:	SKP52_06960(maiA)
SMAG:	AN936_11245
SMAZ:	LH19_12395
SGI:	SGRAN_2937(maiA2)
SWI:	Swit_0831
STAX:	MC45_16570
SPHI:	TS85_14895
SSAN:	NX02_13760
SPHG:	AZE99_12455
BLAS:	BSY18_2910
ELQ:	Ga0102493_113020
ADO:	A6F68_02581(maiA)
GXL:	H845_1040
KEU:	S101446_01674(nicE)
APT:	APA01_23730
APW:	APA42C_23730
APF:	APA03_23730
APU:	APA07_23730
APG:	APA12_23730
APQ:	APA22_23730
APX:	APA26_23730
APZ:	APA32_23730
APK:	APA386B_1207(maiA)
ASV:	WG31_11890
ALI:	AZOLI_p20260 AZOLI_p20437
ABS:	AZOBR_p210125 AZOBR_p480009
ABQ:	ABAZ39_23985 ABAZ39_30190
ABF:	AMK58_22180 AMK58_25915
ATI:	AL072_17670 AL072_27300 AL072_30675
TMO:	TMO_a0282 TMO_a0378 TMO_b0386
TXI:	TH3_02605
PUB:	SAR11_1339
APM:	HIMB5_00009780
APB:	SAR116_0770
PBJ:	VN24_09505
BTS:	Btus_2321
AMT:	Amet_1195
DSY:	DSY0374
DHD:	Dhaf_0302
DDH:	Desde_0317
MSM:	MSMEG_1319 MSMEG_2495 MSMEG_3993 MSMEG_4610
MSG:	MSMEI_1282 MSMEI_2435 MSMEI_3900 MSMEI_4492
MSB:	LJ00_06575 LJ00_12420 LJ00_19835 LJ00_22800
MSN:	LI99_06575 LI99_12420 LI99_19840 LI99_22805
MSH:	LI98_06575 LI98_12425 LI98_19845 LI98_22810
MAB:	MAB_4413c
MABB:	MASS_4450
MMV:	MYCMA_04045
MAY:	LA62_22405
MABO:	NF82_22095
MABL:	MMASJCM_4474
MAZ:	LA61_22300
MAK:	LH56_02270
MYS:	NF92_02320
MYC:	NF90_02320
MCHE:	BB28_22605
MIZ:	BAB75_25065
MJD:	JDM601_2704
MMI:	MMAR_3401
MMAE:	MMARE11_33041
MLI:	MULP_03664
MGO:	AFA91_20420
MPHL:	MPHLCCUG_04301(maiA)
MVQ:	MYVA_2930(maiA)
ASD:	AS9A_3597
NFA:	NFA_21930
NFR:	ERS450000_01905
NCY:	NOCYR_3767
NBR:	O3I_030465
NNO:	NONO_c51200(maiA) NONO_c54880
NSL:	BOX37_12645
RHA:	RHA1_ro00478 RHA1_ro04577
ROP:	ROP_34370(maiA) ROP_44900
ROA:	Pd630_LPD01047 Pd630_LPD03771 Pd630_LPD04577 Pd630_LPD07333
RPY:	Y013_19070
RHB:	NY08_2121
RHW:	BFN03_15150
GBR:	Gbro_4096
GOR:	KTR9_4024
GOQ:	ACH46_09950
GTA:	BCM27_21140 BCM27_25005
SCO:	SCO2823(SCBAC17F8.14c)
SMA:	SAV_5234
SGR:	SGR_354
SGB:	WQO_24580
SVL:	Strvi_4758 Strvi_8170
SCT:	SCAT_2832 SCAT_5468
SCY:	SCATT_28210 SCATT_54680
SBH:	SBI_06829 SBI_08672
SVE:	SVEN_5449
SDV:	BN159_5448
SALB:	XNR_1727
SALS:	SLNWT_2382 SLNWT_4228
SCI:	B446_14860
SRC:	M271_30770 M271_44540
SALU:	DC74_1461 DC74_3288
SALL:	SAZ_07830 SAZ_17520
SLV:	SLIV_23550
SVT:	SVTN_24815 SVTN_27915
STRE:	GZL_05617
SLD:	T261_5273
SXI:	SXIM_39380
STRC:	AA958_10555
SAMB:	SAM23877_2871
SPRI:	SPRI_4712 SPRI_6098
SCZ:	ABE83_19125 ABE83_19765
SCX:	AS200_28270
SRW:	TUE45_06907(maiA)
STRF:	ASR50_13710
SPAV:	Spa2297_12055
SLC:	SL103_05215
SGS:	AVL59_41800
STSI:	A4E84_14900
SLS:	SLINC_3242
SNR:	SNOUR_26265
SPLU:	LK06_010900
STRD:	NI25_24670
ART:	Arth_4067
ARI:	UM93_06555
ARE:	AL755_04310
AAQ:	AOC05_00975
ARH:	AHiyo8_24660 AHiyo8_24670 AHiyo8_36510
ARZ:	AUT26_18910 AUT26_19440
APN:	Asphe3_10480
RSA:	RSal33209_1838(igiC)
KFV:	AS188_01335 AS188_10275
SATK:	SA2016_3806 SA2016_3969
LMOI:	VV02_11305
SERJ:	SGUI_0401
JTE:	ASJ30_15250
PBO:	PACID_31330
PSIM:	KR76_02240
NDA:	Ndas_4753
NAL:	B005_2082
SRO:	Sros_6615
NOA:	BKM31_58615
FRE:	Franean1_3132 Franean1_3716
FRI:	FraEuI1c_3142 FraEuI1c_4424
ACE:	Acel_1639
GOB:	Gobs_1250
MMAR:	MODMU_3889
SEN:	SACE_1839 SACE_4875
SVI:	Svir_30140
AMD:	AMED_7872
AMN:	RAM_40455
AMM:	AMES_7754
AMZ:	B737_7754
AOI:	AORI_4775 AORI_5999 AORI_6705
AJA:	AJAP_05595 AJAP_09440 AJAP_15765(maiA)
AMQ:	AMETH_0217 AMETH_1088 AMETH_2130 AMETH_3950 AMETH_5705
ALU:	BB31_11025 BB31_23880
PDX:	Psed_1036 Psed_4251 Psed_6340
PSEE:	FRP1_17285 FRP1_20585
PSEH:	XF36_05320
PSEQ:	AD006_24740 AD006_28005
PECQ:	AD017_04330 AD017_07600
PHH:	AFB00_17855
SESP:	BN6_40600
AHM:	TL08_10970
ACTI:	UA75_11710 UA75_21005 UA75_24025
ACAD:	UA74_11625 UA74_20510 UA74_23515
ALL:	CRK58853
VMA:	VAB18032_20605
AMS:	AMIS_5020 AMIS_57320
SNA:	Snas_1911
CWO:	Cwoe_3972
GLP:	Glo7428_4235
NON:	NOS3756_48200
AVA:	Ava_4999
NAZ:	Aazo_2601
IPO:	Ilyop_0101
ACO:	Amico_0502
GBA:	J421_5247
HHY:	Halhy_5099
FPSZ:	AMR72_01615
FIN:	KQS_01655
HJE:	HacjB3_12310
HALI:	BV210_07840
HBO:	Hbor_32410
HTU:	Htur_3570
NAT:	NJ7G_2903
NPE:	Natpe_0253
NGE:	Natgr_2292
NOU:	Natoc_2438
HLR:	HALLA_01715 HALLA_10245
FAC:	FACI_IFERC01G0816
FAI:	FAD_1707
PHO:	PH0985(PH0985) PH1150(PH1150)
PAB:	PAB2420
PFU:	PF1344
PFI:	PFC_05935
PYN:	PNA2_1775
PYA:	PYCH_07690
PYS:	Py04_0947
PYC:	TQ32_06050
TKO:	TK0375
TON:	TON_1011
TGA:	TGAM_1479(maiA)
TSI:	TSIB_1221
TBA:	TERMP_01161
THE:	GQS_10405
THA:	TAM4_1581
THM:	CL1_1658
TLT:	OCC_01039
THS:	TES1_1219
TNU:	BD01_1046
TEU:	TEU_11115
TGY:	X802_00250 X802_09605
THV:	ADU37_CDS09460
TCH:	CHITON_1459
TPEP:	A0127_02445
PPAC:	PAP_04900
APE:	APE_2520.1(maiA)
SSO:	SSO2939(maiA)
SOL:	Ssol_0732
SSOA:	SULA_0726
SSOL:	SULB_0728
SSOF:	SULC_0726
STO:	STK_06560 STK_06670
SULA:	BFU36_12570
MCN:	Mcup_0967
AHO:	Ahos_0996 Ahos_2039
AMAN:	B6F84_01570 B6F84_04585 B6F84_09145
CMA:	Cmaq_1394
VDI:	Vdis_0556
ASC:	ASAC_1406
CSU:	CSUB_C1702
BARC:	AOA65_1124(maiA)