KEGG   ORTHOLOGY: K02554Help
Entry
K02554                      KO                                     

Name
mhpD
Definition
2-keto-4-pentenoate hydratase [EC:4.2.1.80]
Pathway
Phenylalanine metabolism
Benzoate degradation
Dioxin degradation
Xylene degradation
Degradation of aromatic compounds
Module
M00545  
Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
M00569  
Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Overview
   01220 Degradation of aromatic compounds
    K02554  mhpD; 2-keto-4-pentenoate hydratase
  Amino acid metabolism
   00360 Phenylalanine metabolism
    K02554  mhpD; 2-keto-4-pentenoate hydratase
  Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K02554  mhpD; 2-keto-4-pentenoate hydratase
   00622 Xylene degradation
    K02554  mhpD; 2-keto-4-pentenoate hydratase
   00621 Dioxin degradation
    K02554  mhpD; 2-keto-4-pentenoate hydratase
KEGG modules [BR:ko00002]
 Pathway module
  Nucleotide and amino acid metabolism
   Aromatic amino acid metabolism
    M00545  Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
     K02554  mhpD; 2-keto-4-pentenoate hydratase
  Secondary metabolism
   Aromatics degradation
    M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
     K02554  mhpD; 2-keto-4-pentenoate hydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.80  2-oxopent-4-enoate hydratase
     K02554  mhpD; 2-keto-4-pentenoate hydratase
BRITE hierarchy
Other DBs
Genes
ECO: 
b0350(mhpD)
ECJ: 
JW0341(mhpD)
EBW: 
BWG_0239(mhpD)
ECOK: 
ECE: 
Z0448(mhpD)
ECS: 
ECs0405(mhpD)
ECF: 
ETW: 
ECSP_0414(mhpD)
ELX: 
EOJ: 
EOI: 
ECO111_0386(mhpD)
EOH: 
ECO103_0332(mhpD)
EOK: 
G2583_0463(mhpD)
ELR: 
ECO55CA74_02225(mhpD)
ECX: 
EcHS_A0414(mhpD)
ECW: 
EcE24377A_0374(mhpD)
ECM: 
EcSMS35_0381(mhpD)
ECY: 
ECSE_0375
ECR: 
ECIAI1_0351(mhpD)
ECQ: 
ECED1_0378(mhpD)
ECK: 
EC55989_0357(mhpD)
ECT: 
ECIAI39_0328(mhpD)
EOC: 
CE10_0318(mhpD)
EUM: 
ECUMN_0393(mhpD)
ELO: 
EC042_0387(mhpD)
ELH: 
ETEC_0406
ESE: 
ECSF_0321
ESO: 
O3O_05570(mhpD)
ESM: 
O3M_19710(mhpD)
ESL: 
O3K_19725(mhpD)
ECL: 
EcolC_3275
EBR: 
ECB_00304(mhpD)
EBD: 
ECBD_3307
EKO: 
EKO11_3492
EKF: 
KO11_21830(mhpD)
EDH: 
EcDH1_3256
EDJ: 
ECDH1ME8569_0337(mhpD)
ENA: 
ECNA114_0333(mhpD)
EUN: 
UMNK88_400
ELW: 
ECW_m0428(mhpD)
ELL: 
WFL_02105(mhpD)
ELP: 
P12B_c0310(mhpD) P12B_c0368(mhpD)
EBL: 
ECD_00304(mhpD)
EBE: 
B21_00308(mhpD)
ECOA: 
APECO78_05270(mhpD)
ECOL: 
LY180_02140
ECOJ: 
P423_01840
ECOO: 
ECRM13514_0496(mhpD)
ECOH: 
ECRM13516_0330(mhpD)
ECOS: 
EC958_0494
SSN: 
SSON_0329(mhpD)
SHQ: 
A0259_05420
KPN: 
KPN_02119(mhpD)
KPU: 
KP1_3214(mhpD)
KPM: 
KPHS_31010
KPP: 
A79E_2125
KPK: 
A593_25650
KPH: 
KPNIH24_12945
KPZ: 
KPNIH27_14850
KPV: 
KPNIH29_15510
KPW: 
KPNIH30_15790
KPY: 
KPNIH31_14645
KPG: 
KPNIH32_15685
KPC: 
KPNIH10_15310
KPQ: 
KPR0928_15285
KPT: 
VK055_0342(mhpD)
KPE: 
KPK_2204(mhpD)
KPO: 
KPN2242_13550(mhpD)
KPR: 
KPR_2664(mhpD)
KPJ: 
N559_2171
KPI: 
D364_10860
KPA: 
KPNJ1_02343
KPS: 
KPNJ2_02303
KPX: 
PMK1_04483(mhpD)
KPB: 
FH42_06690
KPNE: 
KU54_010830
KPNU: 
LI86_10785
KVA: 
Kvar_2156
KVD: 
KR75_23570
KVQ: 
SP68_04225
KOX: 
KOX_22680(mhpD)
KOE: 
A225_3413
KOY: 
J415_14965(mhpD)
KOK: 
KONIH1_16715
KOC: 
AB185_19190
KOM: 
HR38_20975
KQU: 
AVR78_19675
CFD: 
CFNIH1_11845
CIF: 
AL515_06450
EBT: 
EBL_c20010(mhpD)
ROR: 
RORB6_04290(mhpD)
PGE: 
LG71_09605
KIN: 
AB182_20235
KGO: 
CEW81_11385
EBF: 
D782_1985
SLQ: 
M495_05215
SFW: 
WN53_15175
SFG: 
AV650_10715
XCC: 
XCC0145(mhpD)
XCB: 
XC_0154
XCA: 
xcc-b100_0162(mhpD)
XCP: 
XCR_4394
XCV: 
XCV0146
XAC: 
XAC0161(mhpD)
XCI: 
XCAW_00555(mhpD)
XCT: 
J151_00278
XCU: 
J159_00276
XCN: 
J169_00274
XCW: 
J162_00275
XCR: 
J163_00275
XCM: 
J164_00275
XCF: 
J172_00269
XCJ: 
J158_00276
XFU: 
XFF4834R_chr00910(mhpD)
XAX: 
XACM_0146
XAO: 
XAC29_00830
XSA: 
SB85_13000
XTN: 
FD63_00310
XFR: 
BER92_18785
XGA: 
BI317_23985
XVE: 
BJD12_13375
XPE: 
BJD13_16260
SACZ: 
AOT14_00290(mhpD)
STEK: 
AXG53_17725
SRH: 
BAY15_0161
SLM: 
BIZ42_09735
PSU: 
Psesu_0023
PSUW: 
WQ53_07935
LAB: 
LA76x_2653
LAQ: 
GLA29479_2995(mhpD)
LCP: 
LC55x_1529
LGU: 
LG3211_4620
VNA: 
PN96_06260
VEJ: 
VEJY3_06795(mhpD)
VFU: 
vfu_A01973
PCQ: 
PcP3B5_23480(amnF)
PPF: 
Pput_2875 Pput_2890
PPW: 
PputW619_1982 PputW619_2011
PPX: 
T1E_4256 T1E_4272(tobG)
PPUH: 
B479_25875(mhpD)
PMON: 
X969_10885 X969_10960
PMOT: 
X970_10540 X970_10615
PSYR: 
N018_13880
PFE: 
PSF113_2494
PPZ: 
H045_07780
PVR: 
PverR02_10455 PverR02_12300 PverR02_14375
PBA: 
PSEBR_a2351
PDR: 
H681_08420
PSV: 
PVLB_26057(mhpD)
PKC: 
PKB_3259(mhpd1) PKB_3607(mhpd3)
PSW: 
LK03_20490
PPSY: 
AOC04_16955
PSOS: 
POS17_2263
AVN: 
Avin_15110(mhpD)
AVL: 
AvCA_15110(mhpD) AvCA_42150
AVD: 
AvCA6_15110(mhpD) AvCA6_42150
ACX: 
Achr_27770(mhpD)
PUR: 
AOC03_11585
AEI: 
AOY20_01985
AJO: 
RZ95_18615
ASJ: 
AsACE_CH00350(mhpD)
PTN: 
PTRA_a0480
AMC: 
MADE_1016425
AMH: 
I633_17185
AMAA: 
amad1_16620
AMAL: 
I607_15790
AMAE: 
I876_16090
AMAO: 
I634_16035
AMAD: 
I636_15935
AMAI: 
I635_16575
AMAG: 
I533_15630
LAL: 
AT746_01260
TTU: 
TERTU_1258
ZAL: 
AZF00_11825
HJA: 
BST95_10565
HCS: 
FF32_08350
AXE: 
P40_10440
KGE: 
TQ33_0085
KSD: 
KS2013_117
GBI: 
PG2T_05645 PG2T_08020
AQL: 
BXU06_16250 BXU06_17055
RSO: 
RSp0891
RSM: 
CMR15_mp10875(mhpD)
RSE: 
F504_4326
RPJ: 
N234_23035 N234_29175 N234_34805
RIN: 
ACS15_4685(amnF)
REU: 
Reut_A0272 Reut_B5220 Reut_B5499
REH: 
H16_B0884(mhpD3)
CNC: 
CNE_1c17860(mhpD2)
RME: 
Rmet_5207(mhpD)
CBW: 
RR42_m1055 RR42_s1477
CCUP: 
BKK81_06165 BKK81_23315 BKK81_23755 BKK81_25725
BVI: 
Bcep1808_5386
BVE: 
AK36_3500(mhpD)
BUR: 
Bcep18194_B1186 Bcep18194_C7646
BCJ: 
BCAM2124(mhpD)
BCEN: 
DM39_1993(mhpD) DM39_4968(mhpD)
BCEW: 
DM40_5002(mhpD)
BCEO: 
I35_6006(mhpD)
BMUL: 
NP80_3432(mhpD) NP80_3870(amnF)
BCON: 
NL30_34150
BDF: 
WI26_30220
BLAT: 
WK25_27490
BSEM: 
WJ12_26050
BPSL: 
WS57_02990 WS57_12780 WS57_14615
BMEC: 
WJ16_20000
BUG: 
BC1001_0833
BGE: 
BC1002_4115 BC1002_4722
BUK: 
MYA_5004
BUL: 
BW21_2673(mhpD)
BUQ: 
AC233_10935
BPLA: 
bpln_1g12690
BUD: 
AQ610_12645
BXE: 
Bxe_A1149(amnF) Bxe_A3548 Bxe_B2327
BXB: 
DR64_1247(amnF) DR64_3308(mhpD) DR64_4659(mhpD)
BPH: 
Bphy_4537
BRH: 
RBRH_00200
BPX: 
BUPH_00407 BUPH_05360
BPY: 
Bphyt_1466
BFN: 
OI25_257(amnF)
PSPW: 
BJG93_33920
PPK: 
U875_18220
PPNO: 
DA70_10730 DA70_11725
PPNM: 
LV28_19225 LV28_20325
PRB: 
X636_15105 X636_15895
PPUL: 
RO07_14665 RO07_25035
PSPU: 
NA29_07820 NA29_22525
PAPI: 
SG18_14495 SG18_24450
PVE: 
UC34_05800 UC34_22415
POX: 
MB84_08005 MB84_10220
PFG: 
AB870_09230 AB870_16825
PNR: 
AT302_01285 AT302_13270
BAV: 
BAV0598(bphE)
BHZ: 
ACR54_00826(mhpD)
AIS: 
BUW96_12470
TAS: 
TASI_0989
TAT: 
KUM_0455
AFA: 
UZ73_04245
RHY: 
RD110_03310
POL: 
Bpro_5134
ACK: 
C380_15905(bphE)
ACID: 
CBP33_05430
VPD: 
VAPA_1c22820
CTES: 
O987_08272
RGU: 
A4W93_06690
DAR: 
Daro_0905 Daro_1354
AZO: 
azo1974(mhpD)
DTI: 
Desti_4094
MESO: 
BSQ44_18495
AAK: 
AA2016_6635
ARA: 
Arad_7264
BRAD: 
BF49_2647
BIC: 
LMTR13_06465
OCG: 
OCA5_c03450
OCO: 
OCA4_c03440
XAU: 
Xaut_0936
MSL: 
Msil_1477
CHEL: 
AL346_20350
CDQ: 
BOQ54_11025
BVR: 
BVIR_1068
MAAD: 
AZF01_08285
MMED: 
Mame_00144(mhpD)
PSIN: 
CAK95_01480
RBM: 
TEF_21410
CCR: 
CC_1509
CCS: 
CCNA_01577
CAK: 
Caul_1767
CSE: 
Cseg_1571
CHQ: 
AQ619_07560
PZU: 
PHZ_c2453(mhpD)
BSB: 
Bresu_3164
BRD: 
JL11_11900
BRG: 
A4249_07650
BRL: 
BZG35_04755
AEX: 
Astex_2117
CBOT: 
ATE48_09320 ATE48_17630
PAMI: 
JCM7686_pAMI4p288
CON: 
TQ29_16135 TQ29_16180
SUAM: 
BOO69_22170
MMR: 
Mmar10_0237
HBA: 
Hbal_2819
HBC: 
AEM38_01625
NAR: 
Saro_3511 Saro_3854
NPP: 
PP1Y_AT15701 PP1Y_AT31588
NPN: 
JI59_24630
NRE: 
BES08_15200 BES08_18615 BES08_21165
SAL: 
Sala_3044
SPHK: 
SKP52_00925(mhpD) SKP52_04210 SKP52_19500
SPHP: 
LH20_00340 LH20_18745
SMAG: 
AN936_00755 AN936_19360
SMAZ: 
LH19_00765 LH19_23280 LH19_27415
STER: 
AOA14_03880 AOA14_10830 AOA14_11300
SGI: 
SGRAN_0156 SGRAN_1420(mhpD2)
SPHL: 
LPB140_10500
SPHQ: 
BWQ93_09230 BWQ93_09300 BWQ93_09865
SWI: 
Swit_0742 Swit_3520
SPHI: 
TS85_17615
SSAN: 
NX02_10235 NX02_18950
SMY: 
BJP26_13435
SPAN: 
AWL63_09810 AWL63_19825 AWL63_23950
SKR: 
BRX40_21565
SPLM: 
BXU08_00490
SCH: 
Sphch_0679 Sphch_3082
SBD: 
ATN00_11645
SPHR: 
BSY17_3779
BLAS: 
BSY18_3297
ERY: 
CP97_03140 CP97_14220
AMX: 
AM2010_2527
AEP: 
AMC99_00486
ANH: 
A6F65_01023 A6F65_02137(mhpD)
ADO: 
A6F68_01717
CNA: 
AB433_18130
CMAN: 
A9D14_00955 A9D14_15720
GDI: 
GDI2732(mhpD)
ALI: 
AZOLI_p50268
ATI: 
AL072_29115
AHU: 
A6A40_13815
TMO: 
TMO_b0121(todJ)
TXI: 
TH3_13610
MAGQ: 
MGMAQ_0649
PEL: 
SAR11G3_00279
BCA: 
BCE_2155
BCX: 
BCA_2153
BCF: 
bcf_10205
BCER: 
BCK_24230
BTL: 
BALH_1842(pheD)
BMYC: 
DJ92_4636
BPF: 
BpOF4_12600
BMQ: 
BMQ_3589
BMD: 
BMD_3574
BMEG: 
BG04_463
BACI: 
B1NLA3E_08425 B1NLA3E_09295 B1NLA3E_13980
GST: 
HW35_13040
BACO: 
OXB_2504
BSM: 
BSM4216_0947
BSJ: 
UP17_10515
BHK: 
B4U37_13945
GTN: 
GTNG_3153(nbaH)
GYC: 
GYMC61_2296
GYA: 
GYMC52_1424
GCT: 
GC56T3_2057
GMC: 
GY4MC1_1594
GGH: 
GHH_c14820
GJF: 
M493_00035 M493_12205(nahL) M493_17915
GTH: 
Geoth_1677
PTL: 
AOT13_14450
LGY: 
T479_19655
VIG: 
BKP57_09390
LAO: 
AOX59_17240
FPN: 
ABE65_004735
FAR: 
ABE41_004875
BBE: 
BBR47_29760
PNP: 
IJ22_00670 IJ22_32400 IJ22_35290 IJ22_48570
ANX: 
ACH33_11715
AAC: 
Aaci_1621
AAD: 
TC41_1517(mhpD)
BTS: 
Btus_0967
SIV: 
SSIL_0063 SSIL_3692
SSIL: 
SOLI23_18520 SOLI23_19595
CAH: 
CAETHG_2391
GFE: 
Gferi_17965
DCA: 
Desca_1929
DKU: 
Desku_0615
PTH: 
PTH_0481
DOR: 
Desor_0611
TMR: 
Tmar_1784
SAP: 
Sulac_2999
FPLA: 
A4U99_15560
CHY: 
CHY_1278 CHY_1322
MTA: 
Moth_1777
TOC: 
Toce_0376
TTO: 
Thethe_01839
LPIL: 
LIP_2167 LIP_2171
MTU: 
Rv3536c(hsaE)
MTV: 
RVBD_3536c
MTC: 
MT3640(mhpD)
MRA: 
MRA_3575(mhpD)
MTF: 
TBFG_13569
MTB: 
TBMG_03576
MTK: 
TBSG_03602
MTZ: 
TBXG_003551
MTG: 
MRGA327_21845
MTI: 
MRGA423_22340
MTE: 
CCDC5079_3277
MTUR: 
CFBS_3752(mhpD)
MTL: 
CCDC5180_3229
MTO: 
MTCTRI2_3600
MTD: 
UDA_3536c
MTN: 
ERDMAN_3880
MTJ: 
J112_19040
MTUB: 
MT7199_3598(hasE)
MTUE: 
J114_18910
MTX: 
M943_18180
MTUH: 
I917_24815
MTUL: 
TBHG_03476
MTUT: 
HKBT1_3737(mhpD)
MTUU: 
HKBT2_3746(mhpD)
MTQ: 
HKBS1_3749(mhpD)
MBO: 
Mb3566c
MBB: 
BCG_3600c
MBT: 
JTY_3601
MBM: 
BCGMEX_3598c
MBK: 
K60_036740
MBX: 
BCGT_3402
MBZ: 
LH58_19155
MAF: 
MAF_35480
MCE: 
MCAN_35471
MCQ: 
BN44_110028(mhpD)
MCV: 
BN43_90034(mhpD)
MCX: 
BN42_90031(mhpD)
MCZ: 
BN45_100031(mhpD)
MMIC: 
RN08_3912
MPA: 
MAP_0531
MAO: 
MAP4_3336
MAVI: 
RC58_16545
MAVU: 
RE97_16580
MAV: 
MAV_0625
MAVD: 
NF84_02825
MAVR: 
LA63_02890
MAVA: 
LA64_02900
MIT: 
OCO_05350 OCO_14780
MIA: 
OCU_05390 OCU_15220
MIE: 
LG41_02690
MIR: 
OCQ_05500
MID: 
MIP_00989
MYO: 
OEM_05420
MCHI: 
AN480_02675
MSM: 
MSMEG_5940
MSG: 
MSMEI_5780(mhpD)
MSB: 
LJ00_29370
MSN: 
LI99_29375
MSH: 
LI98_29380
MSA: 
Mycsm_01893 Mycsm_01983 Mycsm_05773
MUL: 
MUL_4097
MVA: 
Mvan_4393 Mvan_5236
MGI: 
Mflv_1520
MSP: 
Mspyr1_09040
MAB: 
MAB_0624
MABB: 
MASS_0594
MMV: 
MYCMA_0324
MAY: 
LA62_03155 LA62_22220
MABO: 
NF82_03150 NF82_21910
MABL: 
MMASJCM_0613
MAZ: 
LA61_03070 LA61_22115
MAK: 
LH56_19495
MYS: 
NF92_20005
MYC: 
NF90_20010
MCHE: 
BB28_02990
MIZ: 
BAB75_03740 BAB75_13820
MMC: 
Mmcs_4661 Mmcs_5436
MKM: 
Mkms_4749 Mkms_5833
MJL: 
Mjls_4209 Mjls_5044
MJD: 
JDM601_3681
MMI: 
MMAR_5023
MMAE: 
MMARE11_48330
MRH: 
MycrhN_2294 MycrhN_2955 MycrhN_3139
MMM: 
W7S_02620
MCB: 
Mycch_4601 Mycch_5981
MLI: 
MULP_05275
MKN: 
MKAN_11845 MKAN_22335
MKS: 
LG40_11690 LG40_22120
MKI: 
LH54_11835 LH54_22250
MNE: 
D174_16940 D174_24275
MYV: 
G155_04630 G155_08455
MYE: 
AB431_26365
MGO: 
AFA91_00045 AFA91_11070 AFA91_18395
MFT: 
XA26_08850 XA26_16920
MHAD: 
B586_04630
MPHL: 
MPHLCCUG_00565(tesE)
MVQ: 
MYVA_5131
ASD: 
AS9A_1022
CDR: 
CDHC03_1947(mhpD)
CHN: 
A605_04765
CAZ: 
CARG_03195
CII: 
CIMIT_11790
CMV: 
CMUST_15060(mhpD)
CSTA: 
CSTAT_09795
NFA: 
NFA_30420 NFA_33180 NFA_4650
NFR: 
ERS450000_00751(mhpD_1) ERS450000_01022(mhpD_2) ERS450000_03772(mhpD_4)
NCY: 
NOCYR_0493(mhpD)
NBR: 
O3I_002620
NNO: 
NONO_c04920 NONO_c35080 NONO_c51380(mhpD) NONO_c62060
NSL: 
BOX37_02145 BOX37_11735
NSR: 
NS506_01254(bphH)
RHA: 
RHA1_ro00517 RHA1_ro03881 RHA1_ro04533(hsaE) RHA1_ro05799 RHA1_ro08085(bphE3) RHA1_ro10117(bphE4)
RER: 
RER_07390 RER_57560
REY: 
O5Y_03590 O5Y_27505
REB: 
XU06_03830 XU06_27790
ROP: 
ROP_34180(cmtF) ROP_37500 ROP_44480 ROP_54180 ROP_pROB02-02260
ROA: 
Pd630_LPD00984 Pd630_LPD02418 Pd630_LPD07656 Pd630_LPD12051
REQ: 
REQ_42080
RPY: 
Y013_12565 Y013_15615
RAV: 
AAT18_03890 AAT18_08100 AAT18_09210 AAT18_09395 AAT18_22080
RHW: 
BFN03_15235
GBR: 
Gbro_0224
GPO: 
GPOL_c41190
GOR: 
KTR9_0810(hsaE)
GOQ: 
ACH46_11985
GTA: 
BCM27_05040 BCM27_21920
TPR: 
Tpau_3798
DTM: 
BJL86_0685
SCO: 
SCP1.299 SCP1.55c
SCB: 
SCAB_15211(bphE) SCAB_2091(mhpD)
SSX: 
SACTE_4116
SVL: 
Strvi_3230 Strvi_6066
SBH: 
SBI_01533 SBI_08646
SDV: 
BN159_1390(mhpD)
SALS: 
SLNWT_6913
SRC: 
M271_00320 M271_09220 M271_50385
SALU: 
DC74_7438
SALL: 
SAZ_38395
SVT: 
SVTN_35855
SCZ: 
ABE83_02010
STRF: 
ASR50_31430
SLC: 
SL103_24895
STRT: 
A8713_24495
SGS: 
AVL59_29435
STSI: 
A4E84_36445
SNW: 
BBN63_32965
KSK: 
KSE_23730
MIO: 
AOA12_18545
MVD: 
AWU67_16675
AGY: 
ATC03_02595
ARL: 
AFL94_16310
ARY: 
ATC04_01555
ARZ: 
AUT26_08900 AUT26_19815
PSUL: 
AU252_17315
NAE: 
BHE16_09165
ICA: 
Intca_1096
JTE: 
ASJ30_00095
NDK: 
I601_0559(mhpD)
PSIM: 
KR76_14495 KR76_24180
TCU: 
Tcur_0534
SRO: 
Sros_9115
NOA: 
BKM31_47340
FRE: 
Franean1_2884
FRI: 
FraEuI1c_4106
FSY: 
FsymDg_2036
NML: 
Namu_4085
AMD: 
AMED_8623
AMN: 
RAM_44255
AMM: 
AMES_8492
AMZ: 
B737_8493
AOI: 
AORI_7402(mhpD)
AJA: 
AJAP_01980
AMQ: 
AMETH_5436
ALU: 
BB31_08780 BB31_29200
PDX: 
Psed_2524 Psed_4293
PSEQ: 
AD006_28435 AD006_28735
PECQ: 
AD017_28825 AD017_29125
KAL: 
KALB_5138
KPHY: 
AOZ06_42830
LED: 
BBK82_38940 BBK82_43175
ALL: 
CRK56591 CRK57816 CRK59601
STP: 
Strop_3527
SAQ: 
Sare_3902
MAU: 
Micau_4940
MIL: 
ML5_3355
VMA: 
VAB18032_28756
AMS: 
AMIS_19120
AFS: 
AFR_23755
CWO: 
Cwoe_0439
AYM: 
YM304_39990
RRS: 
RoseRS_2578
RCA: 
Rcas_2405
CAU: 
Caur_1357
CAG: 
Cagg_2039
CHL: 
Chy400_1479
TRO: 
trd_1387
CAP: 
CLDAP_40920
TTJ: 
TTHB239
TTL: 
TtJL18_2421
TSC: 
TSC_c11610
THC: 
TCCBUS3UF1_13020
TOS: 
Theos_2469 Theos_2471
TBC: 
A0O31_00088 A0O31_00090
GES: 
VT84_10640(tesE)
PBOR: 
BSF38_00915(mhpD)
TPI: 
TREPR_1322
CPOR: 
BED41_05590
HDL: 
HALDL1_15840
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Diaz E, Ferrandez A, Prieto MA, Garcia JL.
  Title
Biodegradation of aromatic compounds by Escherichia coli.
  Journal
Microbiol Mol Biol Rev 65:523-69, table of contents (2001)
DOI:10.1128/MMBR.65.4.523-569.2001
Reference
PMID:9098055
  Authors
Ferrandez A, Garcia JL, Diaz E.
  Title
Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12.
  Journal
J Bacteriol 179:2573-81 (1997)
DOI:10.1128/JB.179.8.2573-2581.1997
  Sequence
[eco:b0350]
LinkDB All DBs

KEGG   ORTHOLOGY: K18364Help
Entry
K18364                      KO                                     

Name
bphH, xylJ, tesE
Definition
2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase [EC:4.2.1.80 4.2.1.132]
Pathway
Benzoate degradation
Dioxin degradation
Xylene degradation
Degradation of aromatic compounds
Module
M00569  
Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Overview
   01220 Degradation of aromatic compounds
    K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
  Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
   00622 Xylene degradation
    K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
   00621 Dioxin degradation
    K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
KEGG modules [BR:ko00002]
 Pathway module
  Secondary metabolism
   Aromatics degradation
    M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
     K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.80  2-oxopent-4-enoate hydratase
     K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
    4.2.1.132  2-hydroxyhexa-2,4-dienoate hydratase
     K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
BRITE hierarchy
Other DBs
Genes
PGE: 
PSD: 
PRE: 
PPSE: 
BN5_3620(nahL)
PCQ: 
PcP3B5_25700(tesE_1)
PPUT: 
PPUN: 
PPJ: 
PVR: 
PSC: 
PSTU: 
UIB01_22740
PBM: 
CL52_14710
PPUU: 
PputUW4_01660(mhpD)
PKC: 
PKB_4239(xylJ)
PFZ: 
AV641_10535
PALK: 
PSAKL28_05940
PPSY: 
AOC04_07835
PFK: 
PFAS1_28775
AVN: 
Avin_08670(xylJ) Avin_30610(lapE)
AVL: 
AvCA_08670(xylJ) AvCA_30610(lapE)
AVD: 
AvCA6_08670(xylJ) AvCA6_30610(lapE)
ACX: 
Achr_32770(xylJ) Achr_32780
SPL: 
Spea_2118
SHL: 
Shal_2090
SWD: 
Swoo_1392
COLW: 
A3Q33_18575
PHA: 
PSHAa2141(xylJ)
PTN: 
PTRA_a2594(bphH)
MAD: 
HP15_1113 HP15_4034
MSR: 
AU15_21080
MLQ: 
ASQ50_09215
MSQ: 
BKP64_13850
SPOI: 
IMCC21906_00389 IMCC21906_02710
ZAL: 
AZF00_03890 AZF00_11430 AZF00_17820
HJA: 
BST95_09505
CYQ: 
Q91_0508
CZA: 
CYCME_2103
BLEP: 
AL038_01300
AEH: 
Mlg_2460
APAC: 
S7S_06990
GBI: 
PG2T_02230
TBN: 
TBH_C0928
GPB: 
HDN1F_27090(tesE)
AQL: 
BXU06_16875
RPI: 
Rpic_4620
RPF: 
Rpic12D_3544
RPJ: 
N234_08150 N234_12215
RIN: 
ACS15_4354(dmpE)
REU: 
Reut_A1510 Reut_B5691
REH: 
H16_B0548(mhpD1) H16_B0597(bphH)
CNC: 
CNE_2c04940(mhpD) CNE_2c05420(xylJ2) CNE_BB1p11990(xylJ1) CNE_BB1p13280(xylJ2)
RME: 
Rmet_1321(xylJ)
CTI: 
RALTA_B0401(mhpD)
CBW: 
RR42_s2313 RR42_s2484
CCUP: 
BKK81_19910 BKK81_27090
BVI: 
Bcep1808_7603
BUR: 
Bcep18194_B1459 Bcep18194_B2961
BCJ: 
BCAM1613
BCEN: 
DM39_3383(dmpE) DM39_4834(dmpE)
BCEO: 
I35_5473
BCT: 
GEM_4111 GEM_5403
BCED: 
DM42_4993(dmpE) DM42_6345(dmpE)
BCEP: 
APZ15_31155
BPYR: 
ABD05_27820
BCON: 
NL30_04140 NL30_24600
BDF: 
WI26_15985 WI26_21145
BTEI: 
WS51_00560 WS51_05695
BPSL: 
WS57_06045 WS57_12165
BMEC: 
WJ16_26790
BUQ: 
AC233_11195
BXE: 
Bxe_C1189(bphH)
BXB: 
DR64_8616(dmpE)
BFN: 
OI25_4589(dmpE)
PPK: 
U875_01900
PRB: 
X636_07570
PVE: 
UC34_07065
CDN: 
BN940_01166 BN940_04316
PNA: 
Pnap_4144
AJS: 
Ajs_0222
ACID: 
CBP33_01105
VEI: 
Veis_2785
CTT: 
CtCNB1_1353 CtCNB1_3149
CTES: 
O987_07740
ADN: 
Alide_0337
ADK: 
Alide2_0282
HYL: 
LPB072_18180
MPT: 
Mpe_A2273 Mpe_A3325
JAG: 
GJA_236(xylJ)
MASW: 
AM586_18650
LCH: 
Lcho_3343
RBU: 
PG1C_14105
DAR: 
Daro_2774 Daro_3785
AZO: 
azo1853(lapE) azo2434(nahL)
AZI: 
AzCIB_1507 AzCIB_4411
TMZ: 
Tmz1t_2077 Tmz1t_3091
THU: 
AC731_001810 AC731_008895
ARC: 
ABLL_2444
NAR: 
Saro_3689
NPP: 
PP1Y_AT32745 PP1Y_Mpl3103
NPN: 
JI59_22525
SGI: 
SGRAN_1581(mhpD)
SPHM: 
G432_01985
SSAN: 
NX02_12710
SJP: 
SJA_C1-11870(mhpD)
SYB: 
TZ53_09010 TZ53_23455
SPHB: 
EP837_03394(bphH)
SINB: 
SIDU_08330
AG: 
BAC67694(tesE)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Horinouchi M, Hayashi T, Koshino H, Kurita T, Kudo T
  Title
Identification of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2,4-dienoic acid and related enzymes involved in testosterone degradation in Comamonas testosteroni TA441.
  Journal
Appl Environ Microbiol 71:5275-81 (2005)
DOI:10.1128/AEM.71.9.5275-5281.2005
  Sequence
LinkDB All DBs

KEGG   ENZYME: 4.2.1.80Help
Entry
EC 4.2.1.80                 Enzyme                                 

Name
2-oxopent-4-enoate hydratase;
2-keto-4-pentenoate hydratase;
OEH;
2-keto-4-pentenoate (vinylpyruvate)hydratase;
4-hydroxy-2-oxopentanoate hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming)
Reaction(IUBMB)
4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O [RN:R02601]
Reaction(KEGG)
R02601;
(other) R04781 R05297
Show
Substrate
4-hydroxy-2-oxopentanoate [CPD:C03589]
Product
2-oxopent-4-enoate [CPD:C00596];
H2O [CPD:C00001]
Comment
Also acts, more slowly, on cis-2-oxohex-4-enoate, but not on the trans-isomer.
History
EC 4.2.1.80 created 1984
Pathway
Phenylalanine metabolism
Benzoate degradation
Dioxin degradation
Xylene degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K02554  
2-keto-4-pentenoate hydratase
K18364  
2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
Genes
ECO: 
b0350(mhpD)
ECJ: 
JW0341(mhpD)
EBW: 
BWG_0239(mhpD)
ECOK: 
ECE: 
Z0448(mhpD)
ECS: 
ECs0405(mhpD)
ECF: 
ETW: 
ECSP_0414(mhpD)
ELX: 
EOJ: 
EOI: 
ECO111_0386(mhpD)
EOH: 
ECO103_0332(mhpD)
EOK: 
G2583_0463(mhpD)
ELR: 
ECO55CA74_02225(mhpD)
ECX: 
EcHS_A0414(mhpD)
ECW: 
EcE24377A_0374(mhpD)
ECM: 
EcSMS35_0381(mhpD)
ECY: 
ECSE_0375
ECR: 
ECIAI1_0351(mhpD)
ECQ: 
ECED1_0378(mhpD)
ECK: 
EC55989_0357(mhpD)
ECT: 
ECIAI39_0328(mhpD)
EOC: 
CE10_0318(mhpD)
EUM: 
ECUMN_0393(mhpD)
ELO: 
EC042_0387(mhpD)
ELH: 
ETEC_0406
ESE: 
ECSF_0321
ESO: 
O3O_05570(mhpD)
ESM: 
O3M_19710(mhpD)
ESL: 
O3K_19725(mhpD)
ECL: 
EcolC_3275
EBR: 
ECB_00304(mhpD)
EBD: 
ECBD_3307
EKO: 
EKO11_3492
EKF: 
KO11_21830(mhpD)
EDH: 
EcDH1_3256
EDJ: 
ECDH1ME8569_0337(mhpD)
ENA: 
ECNA114_0333(mhpD)
EUN: 
UMNK88_400
ELW: 
ECW_m0428(mhpD)
ELL: 
WFL_02105(mhpD)
ELP: 
P12B_c0310(mhpD) P12B_c0368(mhpD)
EBL: 
ECD_00304(mhpD)
EBE: 
B21_00308(mhpD)
ECOA: 
APECO78_05270(mhpD)
ECOL: 
LY180_02140
ECOJ: 
P423_01840
ECOO: 
ECRM13514_0496(mhpD)
ECOH: 
ECRM13516_0330(mhpD)
ECOS: 
EC958_0494
SSN: 
SSON_0329(mhpD)
SHQ: 
A0259_05420
KPN: 
KPN_02119(mhpD)
KPU: 
KP1_3214(mhpD)
KPM: 
KPHS_31010
KPP: 
A79E_2125
KPK: 
A593_25650
KPH: 
KPNIH24_12945
KPZ: 
KPNIH27_14850
KPV: 
KPNIH29_15510
KPW: 
KPNIH30_15790
KPY: 
KPNIH31_14645
KPG: 
KPNIH32_15685
KPC: 
KPNIH10_15310
KPQ: 
KPR0928_15285
KPT: 
VK055_0342(mhpD)
KPE: 
KPK_2204(mhpD)
KPO: 
KPN2242_13550(mhpD)
KPR: 
KPR_2664(mhpD)
KPJ: 
N559_2171
KPI: 
D364_10860
KPA: 
KPNJ1_02343
KPS: 
KPNJ2_02303
KPX: 
PMK1_04483(mhpD)
KPB: 
FH42_06690
KPNE: 
KU54_010830
KPNU: 
LI86_10785
KVA: 
Kvar_2156
KVD: 
KR75_23570
KVQ: 
SP68_04225
KOX: 
KOX_22680(mhpD)
KOE: 
A225_3413
KOY: 
J415_14965(mhpD)
KOK: 
KONIH1_16715
KOC: 
AB185_19190
KOM: 
HR38_20975
KQU: 
AVR78_19675
CFD: 
CFNIH1_11845
CIF: 
AL515_06450
EBT: 
EBL_c20010(mhpD)
ROR: 
RORB6_04290(mhpD)
PGE: 
LG71_09605 LG71_12240
KIN: 
AB182_20235
KGO: 
CEW81_11385
EBF: 
D782_1985
SLQ: 
M495_05215
SFW: 
WN53_15175
SFG: 
AV650_10715
XCC: 
XCC0145(mhpD)
XCB: 
XC_0154
XCA: 
xcc-b100_0162(mhpD)
XCP: 
XCR_4394
XCV: 
XCV0146
XAC: 
XAC0161(mhpD)
XCI: 
XCAW_00555(mhpD)
XCT: 
J151_00278
XCU: 
J159_00276
XCN: 
J169_00274
XCW: 
J162_00275
XCR: 
J163_00275
XCM: 
J164_00275
XCF: 
J172_00269
XCJ: 
J158_00276
XFU: 
XFF4834R_chr00910(mhpD)
XAX: 
XACM_0146
XAO: 
XAC29_00830
XSA: 
SB85_13000
XTN: 
FD63_00310
XFR: 
BER92_18785
XGA: 
BI317_23985
XVE: 
BJD12_13375
XPE: 
BJD13_16260
SACZ: 
AOT14_00290(mhpD)
STEK: 
AXG53_17725
SRH: 
BAY15_0161
SLM: 
BIZ42_09735
PSU: 
Psesu_0023
PSUW: 
WQ53_07935
PSD: 
DSC_09160 DSC_09365
LAB: 
LA76x_2653
LAQ: 
GLA29479_2995(mhpD)
LCP: 
LC55x_1529
LGU: 
LG3211_4620
VNA: 
PN96_06260
VEJ: 
VEJY3_06795(mhpD)
VFU: 
vfu_A01973
PRE: 
PCA10_13820 PCA10_p0350(carD)
PPSE: 
BN5_3620(nahL)
PCQ: 
PcP3B5_23480(amnF) PcP3B5_25700(tesE_1)
PPF: 
Pput_2875 Pput_2890
PPW: 
PputW619_1982 PputW619_2011
PPX: 
T1E_4256 T1E_4272(tobG)
PPUH: 
B479_25875(mhpD)
PPUT: 
L483_14065
PPUN: 
PP4_27260
PMON: 
X969_10885 X969_10960
PMOT: 
X970_10540 X970_10615
PPJ: 
RK21_04237
PSYR: 
N018_13880
PFE: 
PSF113_2494
PPZ: 
H045_07780
PVR: 
PverR02_10455 PverR02_11595 PverR02_12300 PverR02_14375 PverR02_14690
PSC: 
A458_06520
PSTU: 
UIB01_22740
PBM: 
CL52_14710
PBA: 
PSEBR_a2351
PPUU: 
PputUW4_01660(mhpD)
PDR: 
H681_08420
PSV: 
PVLB_26057(mhpD)
PKC: 
PKB_3259(mhpd1) PKB_3607(mhpd3) PKB_4239(xylJ)
PFZ: 
AV641_10535
PALK: 
PSAKL28_05940
PSW: 
LK03_20490
PPSY: 
AOC04_07835 AOC04_16955
PSOS: 
POS17_2263
PFK: 
PFAS1_28775
AVN: 
Avin_08670(xylJ) Avin_15110(mhpD) Avin_30610(lapE)
AVL: 
AvCA_08670(xylJ) AvCA_15110(mhpD) AvCA_30610(lapE) AvCA_42150
AVD: 
AvCA6_08670(xylJ) AvCA6_15110(mhpD) AvCA6_30610(lapE) AvCA6_42150
ACX: 
Achr_27770(mhpD) Achr_32770(xylJ) Achr_32780
PUR: 
AOC03_11585
AEI: 
AOY20_01985
AJO: 
RZ95_18615
ASJ: 
AsACE_CH00350(mhpD)
SPL: 
Spea_2118
SHL: 
Shal_2090
SWD: 
Swoo_1392
COLW: 
A3Q33_18575
PHA: 
PSHAa2141(xylJ)
PTN: 
PTRA_a0480 PTRA_a2594(bphH)
MAD: 
HP15_1113 HP15_4034
MSR: 
AU15_21080
MLQ: 
ASQ50_09215
MSQ: 
BKP64_13850
AMC: 
MADE_1016425
AMH: 
I633_17185
AMAA: 
amad1_16620
AMAL: 
I607_15790
AMAE: 
I876_16090
AMAO: 
I634_16035
AMAD: 
I636_15935
AMAI: 
I635_16575
AMAG: 
I533_15630
LAL: 
AT746_01260
TTU: 
TERTU_1258
SPOI: 
IMCC21906_00389 IMCC21906_02710
ZAL: 
AZF00_03890 AZF00_11430 AZF00_11825 AZF00_17820
HJA: 
BST95_09505 BST95_10565
CYQ: 
Q91_0508
CZA: 
CYCME_2103
BLEP: 
AL038_01300
AEH: 
Mlg_2460
HCS: 
FF32_08350
APAC: 
S7S_06990
AXE: 
P40_10440
KGE: 
TQ33_0085
KSD: 
KS2013_117
GBI: 
PG2T_02230 PG2T_05645 PG2T_08020
TBN: 
TBH_C0928
GPB: 
HDN1F_27090(tesE)
AQL: 
BXU06_16250 BXU06_16875 BXU06_17055
RSO: 
RSp0891
RSM: 
CMR15_mp10875(mhpD)
RSE: 
F504_4326
RPI: 
Rpic_4620
RPF: 
Rpic12D_3544
RPJ: 
N234_08150 N234_12215 N234_23035 N234_29175 N234_34805
RIN: 
ACS15_4354(dmpE) ACS15_4685(amnF)
REU: 
Reut_A0272 Reut_A1510 Reut_B5220 Reut_B5499 Reut_B5691
REH: 
H16_B0548(mhpD1) H16_B0597(bphH) H16_B0884(mhpD3)
CNC: 
CNE_1c17860(mhpD2) CNE_2c04940(mhpD) CNE_2c05420(xylJ2) CNE_BB1p11990(xylJ1) CNE_BB1p13280(xylJ2)
RME: 
Rmet_1321(xylJ) Rmet_5207(mhpD)
CTI: 
RALTA_B0401(mhpD)
CBW: 
RR42_m1055 RR42_s1477 RR42_s2313 RR42_s2484
CCUP: 
BKK81_06165 BKK81_19910 BKK81_23315 BKK81_23755 BKK81_25725 BKK81_27090
BVI: 
Bcep1808_5386 Bcep1808_7603
BVE: 
AK36_3500(mhpD)
BUR: 
Bcep18194_B1186 Bcep18194_B1459 Bcep18194_B2961 Bcep18194_C7646
BCJ: 
BCAM1613 BCAM2124(mhpD)
BCEN: 
DM39_1993(mhpD) DM39_3383(dmpE) DM39_4834(dmpE) DM39_4968(mhpD)
BCEW: 
DM40_5002(mhpD)
BCEO: 
I35_5473 I35_6006(mhpD)
BMUL: 
NP80_3432(mhpD) NP80_3870(amnF)
BCT: 
GEM_4111 GEM_5403
BCED: 
DM42_4993(dmpE) DM42_6345(dmpE)
BCEP: 
APZ15_31155
BPYR: 
ABD05_27820
BCON: 
NL30_04140 NL30_24600 NL30_34150
BDF: 
WI26_15985 WI26_21145 WI26_30220
BLAT: 
WK25_27490
BTEI: 
WS51_00560 WS51_05695
BSEM: 
WJ12_26050
BPSL: 
WS57_02990 WS57_06045 WS57_12165 WS57_12780 WS57_14615
BMEC: 
WJ16_20000 WJ16_26790
BUG: 
BC1001_0833
BGE: 
BC1002_4115 BC1002_4722
BUK: 
MYA_5004
BUL: 
BW21_2673(mhpD)
BUQ: 
AC233_10935 AC233_11195
BPLA: 
bpln_1g12690
BUD: 
AQ610_12645
BXE: 
Bxe_A1149(amnF) Bxe_A3548 Bxe_B2327 Bxe_C1189(bphH)
BXB: 
DR64_1247(amnF) DR64_3308(mhpD) DR64_4659(mhpD) DR64_8616(dmpE)
BPH: 
Bphy_4537
BRH: 
RBRH_00200
BPX: 
BUPH_00407 BUPH_05360
BPY: 
Bphyt_1466
BFN: 
OI25_257(amnF) OI25_4589(dmpE)
PSPW: 
BJG93_33920
PPK: 
U875_01900 U875_18220
PPNO: 
DA70_10730 DA70_11725
PPNM: 
LV28_19225 LV28_20325
PRB: 
X636_07570 X636_15105 X636_15895
PPUL: 
RO07_14665 RO07_25035
PSPU: 
NA29_07820 NA29_22525
PAPI: 
SG18_14495 SG18_24450
PVE: 
UC34_05800 UC34_07065 UC34_22415
POX: 
MB84_08005 MB84_10220
PFG: 
AB870_09230 AB870_16825
PNR: 
AT302_01285 AT302_13270
BAV: 
BAV0598(bphE)
BHZ: 
ACR54_00826(mhpD)
AIS: 
BUW96_12470
TAS: 
TASI_0989
TAT: 
KUM_0455
CDN: 
BN940_01166 BN940_04316
AFA: 
UZ73_04245
RHY: 
RD110_03310
POL: 
Bpro_5134
PNA: 
Pnap_4144
AJS: 
Ajs_0222
ACK: 
C380_15905(bphE)
ACID: 
CBP33_01105 CBP33_05430
VEI: 
Veis_2785
VPD: 
VAPA_1c22820
CTT: 
CtCNB1_1353 CtCNB1_3149
CTES: 
O987_07740 O987_08272
ADN: 
Alide_0337
ADK: 
Alide2_0282
HYL: 
LPB072_18180
MPT: 
Mpe_A2273 Mpe_A3325
JAG: 
GJA_236(xylJ)
MASW: 
AM586_18650
LCH: 
Lcho_3343
RGU: 
A4W93_06690
RBU: 
PG1C_14105
DAR: 
Daro_0905 Daro_1354 Daro_2774 Daro_3785
AZO: 
azo1853(lapE) azo1974(mhpD) azo2434(nahL)
AZI: 
AzCIB_1507 AzCIB_4411
TMZ: 
Tmz1t_2077 Tmz1t_3091
THU: 
AC731_001810 AC731_008895
ARC: 
ABLL_2444
DTI: 
Desti_4094
MESO: 
BSQ44_18495
AAK: 
AA2016_6635
ARA: 
Arad_7264
BRAD: 
BF49_2647
BIC: 
LMTR13_06465
OCG: 
OCA5_c03450
OCO: 
OCA4_c03440
XAU: 
Xaut_0936
MSL: 
Msil_1477
CHEL: 
AL346_20350
CDQ: 
BOQ54_11025
BVR: 
BVIR_1068
MAAD: 
AZF01_08285
MMED: 
Mame_00144(mhpD)
PSIN: 
CAK95_01480
RBM: 
TEF_21410
CCR: 
CC_1509
CCS: 
CCNA_01577
CAK: 
Caul_1767
CSE: 
Cseg_1571
CHQ: 
AQ619_07560
PZU: 
PHZ_c2453(mhpD)
BSB: 
Bresu_3164
BRD: 
JL11_11900
BRG: 
A4249_07650
BRL: 
BZG35_04755
AEX: 
Astex_2117
CBOT: 
ATE48_09320 ATE48_17630
PAMI: 
JCM7686_pAMI4p288
CON: 
TQ29_16135 TQ29_16180
SUAM: 
BOO69_22170
MMR: 
Mmar10_0237
HBA: 
Hbal_2819
HBC: 
AEM38_01625
NAR: 
Saro_3511 Saro_3689 Saro_3854
NPP: 
PP1Y_AT15701 PP1Y_AT31588 PP1Y_AT32745 PP1Y_Mpl3103
NPN: 
JI59_22525 JI59_24630
NRE: 
BES08_15200 BES08_18615 BES08_21165
SAL: 
Sala_3044
SPHK: 
SKP52_00925(mhpD) SKP52_04210 SKP52_19500
SPHP: 
LH20_00340 LH20_18745
SMAG: 
AN936_00755 AN936_19360
SMAZ: 
LH19_00765 LH19_23280 LH19_27415
STER: 
AOA14_03880 AOA14_10830 AOA14_11300
SGI: 
SGRAN_0156 SGRAN_1420(mhpD2) SGRAN_1581(mhpD)
SPHL: 
LPB140_10500
SPHQ: 
BWQ93_09230 BWQ93_09300 BWQ93_09865
SWI: 
Swit_0742 Swit_3520
SPHM: 
G432_01985
SPHI: 
TS85_17615
SSAN: 
NX02_10235 NX02_12710 NX02_18950
SMY: 
BJP26_13435
SPAN: 
AWL63_09810 AWL63_19825 AWL63_23950
SKR: 
BRX40_21565
SPLM: 
BXU08_00490
SJP: 
SJA_C1-11870(mhpD)
SCH: 
Sphch_0679 Sphch_3082
SYB: 
TZ53_09010 TZ53_23455
SBD: 
ATN00_11645
SPHB: 
EP837_03394(bphH)
SPHR: 
BSY17_3779
SINB: 
SIDU_08330
BLAS: 
BSY18_3297
ERY: 
CP97_03140 CP97_14220
AMX: 
AM2010_2527
AEP: 
AMC99_00486
ANH: 
A6F65_01023 A6F65_02137(mhpD)
ADO: 
A6F68_01717
CNA: 
AB433_18130
CMAN: 
A9D14_00955 A9D14_15720
GDI: 
GDI2732(mhpD)
ALI: 
AZOLI_p50268
ATI: 
AL072_29115
AHU: 
A6A40_13815
TMO: 
TMO_b0121(todJ)
TXI: 
TH3_13610
MAGQ: 
MGMAQ_0649
PEL: 
SAR11G3_00279
BCA: 
BCE_2155
BCX: 
BCA_2153
BCF: 
bcf_10205
BCER: 
BCK_24230
BTL: 
BALH_1842(pheD)
BMYC: 
DJ92_4636
BPF: 
BpOF4_12600
BMQ: 
BMQ_3589
BMD: 
BMD_3574
BMEG: 
BG04_463
BACI: 
B1NLA3E_08425 B1NLA3E_09295 B1NLA3E_13980
GST: 
HW35_13040
BACO: 
OXB_2504
BSM: 
BSM4216_0947
BSJ: 
UP17_10515
BHK: 
B4U37_13945
GTN: 
GTNG_3153(nbaH)
GYC: 
GYMC61_2296
GYA: 
GYMC52_1424
GCT: 
GC56T3_2057
GMC: 
GY4MC1_1594
GGH: 
GHH_c14820
GJF: 
M493_00035 M493_12205(nahL) M493_17915
GTH: 
Geoth_1677
PTL: 
AOT13_14450
LGY: 
T479_19655
VIG: 
BKP57_09390
LAO: 
AOX59_17240
FPN: 
ABE65_004735
FAR: 
ABE41_004875
BBE: 
BBR47_29760
PNP: 
IJ22_00670 IJ22_32400 IJ22_35290 IJ22_48570
ANX: 
ACH33_11715
AAC: 
Aaci_1621
AAD: 
TC41_1517(mhpD)
BTS: 
Btus_0967
SIV: 
SSIL_0063 SSIL_3692
SSIL: 
SOLI23_18520 SOLI23_19595
CAH: 
CAETHG_2391
GFE: 
Gferi_17965
DCA: 
Desca_1929
DKU: 
Desku_0615
PTH: 
PTH_0481
DOR: 
Desor_0611
TMR: 
Tmar_1784
SAP: 
Sulac_2999
FPLA: 
A4U99_15560
CHY: 
CHY_1278 CHY_1322
MTA: 
Moth_1777
TOC: 
Toce_0376
TTO: 
Thethe_01839
LPIL: 
LIP_2167 LIP_2171
MTU: 
Rv3536c(hsaE)
MTV: 
RVBD_3536c
MTC: 
MT3640(mhpD)
MRA: 
MRA_3575(mhpD)
MTF: 
TBFG_13569
MTB: 
TBMG_03576
MTK: 
TBSG_03602
MTZ: 
TBXG_003551
MTG: 
MRGA327_21845
MTI: 
MRGA423_22340
MTE: 
CCDC5079_3277
MTUR: 
CFBS_3752(mhpD)
MTL: 
CCDC5180_3229
MTO: 
MTCTRI2_3600
MTD: 
UDA_3536c
MTN: 
ERDMAN_3880
MTJ: 
J112_19040
MTUB: 
MT7199_3598(hasE)
MTUE: 
J114_18910
MTX: 
M943_18180
MTUH: 
I917_24815
MTUL: 
TBHG_03476
MTUT: 
HKBT1_3737(mhpD)
MTUU: 
HKBT2_3746(mhpD)
MTQ: 
HKBS1_3749(mhpD)
MBO: 
Mb3566c
MBB: 
BCG_3600c
MBT: 
JTY_3601
MBM: 
BCGMEX_3598c
MBK: 
K60_036740
MBX: 
BCGT_3402
MBZ: 
LH58_19155
MAF: 
MAF_35480
MCE: 
MCAN_35471
MCQ: 
BN44_110028(mhpD)
MCV: 
BN43_90034(mhpD)
MCX: 
BN42_90031(mhpD)
MCZ: 
BN45_100031(mhpD)
MMIC: 
RN08_3912
MPA: 
MAP_0531
MAO: 
MAP4_3336
MAVI: 
RC58_16545
MAVU: 
RE97_16580
MAV: 
MAV_0625
MAVD: 
NF84_02825
MAVR: 
LA63_02890
MAVA: 
LA64_02900
MIT: 
OCO_05350 OCO_14780
MIA: 
OCU_05390 OCU_15220
MIE: 
LG41_02690
MIR: 
OCQ_05500
MID: 
MIP_00989
MYO: 
OEM_05420
MCHI: 
AN480_02675
MSM: 
MSMEG_5940
MSG: 
MSMEI_5780(mhpD)
MSB: 
LJ00_29370
MSN: 
LI99_29375
MSH: 
LI98_29380
MSA: 
Mycsm_01893 Mycsm_01983 Mycsm_05773
MUL: 
MUL_4097
MVA: 
Mvan_4393 Mvan_5236
MGI: 
Mflv_1520
MSP: 
Mspyr1_09040
MAB: 
MAB_0624
MABB: 
MASS_0594
MMV: 
MYCMA_0324
MAY: 
LA62_03155 LA62_22220
MABO: 
NF82_03150 NF82_21910
MABL: 
MMASJCM_0613
MAZ: 
LA61_03070 LA61_22115
MAK: 
LH56_19495
MYS: 
NF92_20005
MYC: 
NF90_20010
MCHE: 
BB28_02990
MIZ: 
BAB75_03740 BAB75_13820
MMC: 
Mmcs_4661 Mmcs_5436
MKM: 
Mkms_4749 Mkms_5833
MJL: 
Mjls_4209 Mjls_5044
MJD: 
JDM601_3681
MMI: 
MMAR_5023
MMAE: 
MMARE11_48330
MRH: 
MycrhN_2294 MycrhN_2955 MycrhN_3139
MMM: 
W7S_02620
MCB: 
Mycch_4601 Mycch_5981
MLI: 
MULP_05275
MKN: 
MKAN_11845 MKAN_22335
MKS: 
LG40_11690 LG40_22120
MKI: 
LH54_11835 LH54_22250
MNE: 
D174_16940 D174_24275
MYV: 
G155_04630 G155_08455
MYE: 
AB431_26365
MGO: 
AFA91_00045 AFA91_11070 AFA91_18395
MFT: 
XA26_08850 XA26_16920
MHAD: 
B586_04630
MPHL: 
MPHLCCUG_00565(tesE)
MVQ: 
MYVA_5131
ASD: 
AS9A_1022
CDR: 
CDHC03_1947(mhpD)
CHN: 
A605_04765
CAZ: 
CARG_03195
CII: 
CIMIT_11790
CMV: 
CMUST_15060(mhpD)
CSTA: 
CSTAT_09795
NFA: 
NFA_30420 NFA_33180 NFA_4650
NFR: 
ERS450000_00751(mhpD_1) ERS450000_01022(mhpD_2) ERS450000_03772(mhpD_4)
NCY: 
NOCYR_0493(mhpD)
NBR: 
O3I_002620
NNO: 
NONO_c04920 NONO_c35080 NONO_c51380(mhpD) NONO_c62060
NSL: 
BOX37_02145 BOX37_11735
NSR: 
NS506_01254(bphH)
RHA: 
RHA1_ro00517 RHA1_ro03881 RHA1_ro04533(hsaE) RHA1_ro05799 RHA1_ro08085(bphE3) RHA1_ro10117(bphE4)
RER: 
RER_07390 RER_57560
REY: 
O5Y_03590 O5Y_27505
REB: 
XU06_03830 XU06_27790
ROP: 
ROP_34180(cmtF) ROP_37500 ROP_44480 ROP_54180 ROP_pROB02-02260
ROA: 
Pd630_LPD00984 Pd630_LPD02418 Pd630_LPD07656 Pd630_LPD12051
REQ: 
REQ_42080
RPY: 
Y013_12565 Y013_15615
RAV: 
AAT18_03890 AAT18_08100 AAT18_09210 AAT18_09395 AAT18_22080
RHW: 
BFN03_15235
GBR: 
Gbro_0224
GPO: 
GPOL_c41190
GOR: 
KTR9_0810(hsaE)
GOQ: 
ACH46_11985
GTA: 
BCM27_05040 BCM27_21920
TPR: 
Tpau_3798
DTM: 
BJL86_0685
SCO: 
SCP1.299 SCP1.55c
SCB: 
SCAB_15211(bphE) SCAB_2091(mhpD)
SSX: 
SACTE_4116
SVL: 
Strvi_3230 Strvi_6066
SBH: 
SBI_01533 SBI_08646
SDV: 
BN159_1390(mhpD)
SALS: 
SLNWT_6913
SRC: 
M271_00320 M271_09220 M271_50385
SALU: 
DC74_7438
SALL: 
SAZ_38395
SVT: 
SVTN_35855
SCZ: 
ABE83_02010
STRF: 
ASR50_31430
SLC: 
SL103_24895
STRT: 
A8713_24495
SGS: 
AVL59_29435
STSI: 
A4E84_36445
SNW: 
BBN63_32965
KSK: 
KSE_23730
MIO: 
AOA12_18545
MVD: 
AWU67_16675
AGY: 
ATC03_02595
ARL: 
AFL94_16310
ARY: 
ATC04_01555
ARZ: 
AUT26_08900 AUT26_19815
PSUL: 
AU252_17315
NAE: 
BHE16_09165
ICA: 
Intca_1096
JTE: 
ASJ30_00095
NDK: 
I601_0559(mhpD)
PSIM: 
KR76_14495 KR76_24180
TCU: 
Tcur_0534
SRO: 
Sros_9115
NOA: 
BKM31_47340
FRE: 
Franean1_2884
FRI: 
FraEuI1c_4106
FSY: 
FsymDg_2036
NML: 
Namu_4085
AMD: 
AMED_8623
AMN: 
RAM_44255
AMM: 
AMES_8492
AMZ: 
B737_8493
AOI: 
AORI_7402(mhpD)
AJA: 
AJAP_01980
AMQ: 
AMETH_5436
ALU: 
BB31_08780 BB31_29200
PDX: 
Psed_2524 Psed_4293
PSEQ: 
AD006_28435 AD006_28735
PECQ: 
AD017_28825 AD017_29125
KAL: 
KALB_5138
KPHY: 
AOZ06_42830
LED: 
BBK82_38940 BBK82_43175
ALL: 
CRK56591 CRK57816 CRK59601
STP: 
Strop_3527
SAQ: 
Sare_3902
MAU: 
Micau_4940
MIL: 
ML5_3355
VMA: 
VAB18032_28756
AMS: 
AMIS_19120
AFS: 
AFR_23755
CWO: 
Cwoe_0439
AYM: 
YM304_39990
RRS: 
RoseRS_2578
RCA: 
Rcas_2405
CAU: 
Caur_1357
CAG: 
Cagg_2039
CHL: 
Chy400_1479
TRO: 
trd_1387
CAP: 
CLDAP_40920
TTJ: 
TTHB239
TTL: 
TtJL18_2421
TSC: 
TSC_c11610
THC: 
TCCBUS3UF1_13020
TOS: 
Theos_2469 Theos_2471
TBC: 
A0O31_00088 A0O31_00090
GES: 
VT84_10640(tesE)
PBOR: 
BSF38_00915(mhpD)
TPI: 
TREPR_1322
CPOR: 
BED41_05590
HDL: 
HALDL1_15840
 » show all
Taxonomy
Reference
1  [PMID:7287632]
  Authors
Kunz DA, Ribbons DW, Chapman PJ.
  Title
Metabolism of allylglycine and cis-crotylglycine by Pseudomonas putida (arvilla) mt-2 harboring a TOL plasmid.
  Journal
J. Bacteriol. 148 (1981) 72-82.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
64427-80-1
LinkDB All DBs

KEGG   REACTION: R02601Help
Entry
R02601                      Reaction                               

Name
4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming)
Definition
2-Hydroxy-2,4-pentadienoate + H2O <=> 4-Hydroxy-2-oxopentanoate
Equation
Reaction class
C00596_C03589
Enzyme
Pathway
Phenylalanine metabolism
Benzoate degradation
Dioxin degradation
Xylene degradation
Metabolic pathways
Microbial metabolism in diverse environments
Degradation of aromatic compounds
Module
M00545  
Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
M00569  
Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Orthology
K02554  
2-keto-4-pentenoate hydratase [EC:4.2.1.80]
K18364  
2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase [EC:4.2.1.80 4.2.1.132]
Other DBs
RHEA: 
LinkDB All DBs

DBGET integrated database retrieval system