KEGG   ORTHOLOGY: K03094Help
Entry
K03094                      KO                                     
Name
SKP1, CBF3D
Definition
S-phase kinase-associated protein 1
Pathway
Cell cycle
Cell cycle - yeast
Oocyte meiosis
Ubiquitin mediated proteolysis
Protein processing in endoplasmic reticulum
Wnt signaling pathway
TGF-beta signaling pathway
Circadian rhythm
Herpes simplex infection
Module
M00379  
SCF-MET30 complex
M00380  
SCF-BTRC complex
M00381  
SCF-SKP2 complex
M00382  
SCF-FBS complex
M00387  
SCF-FBW7 complex
M00407  
SCF-CDC4 complex
M00411  
SCF-GRR1 complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04120 Ubiquitin mediated proteolysis
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04350 TGF-beta signaling pathway
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04111 Cell cycle - yeast
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04114 Oocyte meiosis
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 Organismal Systems
  Environmental adaptation
   04710 Circadian rhythm
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 Human Diseases
  Infectious diseases
   05168 Herpes simplex infection
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
KEGG pathway modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00379  SCF-MET30 complex [BR:ko04121]
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00380  SCF-BTRC complex [BR:ko04121]
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00381  SCF-SKP2 complex [BR:ko04121]
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00382  SCF-FBS complex [BR:ko04121]
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00407  SCF-CDC4 complex [BR:ko04121]
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00411  SCF-GRR1 complex [BR:ko04121]
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00387  SCF-FBW7 complex [BR:ko04121]
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  multi subunit Ring-finger type E3
   SCF complex
    adaptor protein
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   Cul7 complex
    adaptor protein
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Kinetochore proteins
    CBF3 complex
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
  Centrosomal proteins
   Centrosome duplication proteins
    Other centrosome duplication proteins
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
BRITE hierarchy
Other DBs
COG: 
Genes
HSA: 
6500(SKP1)
PTR: 
PPS: 
GGO: 
PON: 
MCC: 
MMU: 
21402(Skp1a)
RNO: 
287280(Skp1)
CFA: 
474682(SKP1)
AML: 
FCA: 
101099017(SKP1)
BTA: 
615427(SKP1)
ECB: 
100062946
MDO: 
100014810
SHR: 
100927300(SKP1)
OAA: 
100082264 100082731
GGA: 
416319(SKP1)
MGP: 
100544772
TGU: 
100225726(SKP1)
ACS: 
100568037
XLA: 
380538(skp1)
XTR: 
549273(skp1)
DRE: 
393716(skp1)
TRU: 
101068627
OLA: 
101173567
BFO: 
BRAFLDRAFT_124598
CIN: 
100181511
SPU: 
594639
DME: 
Dmel_CG11941(skpC) Dmel_CG11942(skpE) Dmel_CG12227(skpF) Dmel_CG12700(skpD) Dmel_CG15800 Dmel_CG16983(skpA) Dmel_CG8881(skpB)
DPO: 
Dpse_GA14255 Dpse_GA21386 Dpse_GA22610
DAN: 
Dana_GF11136 Dana_GF11848 Dana_GF21176 Dana_GF21823
DER: 
Dere_GG12805 Dere_GG19259 Dere_GG20001 Dere_GG20030 Dere_GG22608
DPE: 
Dper_GL12870 Dper_GL13358 Dper_GL13359 Dper_GL14141 Dper_GL15335 Dper_GL16990 Dper_GL19294
DSE: 
Dsec_GM15542 Dsec_GM19084 Dsec_GM20386 Dsec_GM22995
DSI: 
Dsim_GD16521 Dsim_GD17469 Dsim_GD25016 Dsim_GD25046 Dsim_GD25859
DWI: 
Dwil_GK16428 Dwil_GK21342
DYA: 
Dyak_GE11534 Dyak_GE11566 Dyak_GE13476 Dyak_GE16631(Dyak_skpA)
DGR: 
Dgri_GH19712 Dgri_GH20861 Dgri_GH24518 Dgri_GH24737
DMO: 
Dmoj_GI14776 Dmoj_GI15084 Dmoj_GI20969
DVI: 
Dvir_GJ18822 Dvir_GJ18891 Dvir_GJ20688
AGA: 
AgaP_AGAP008719
AAG: 
AaeL_AAEL009160 AaeL_AAEL010651 AaeL_AAEL010692
CQU: 
CpipJ_CPIJ009705
AME: 
409234(skp1)
NVI: 
100117592(NV18217) 100119117(Skp1)
TCA: 
663380(skp1)
API: 
100164917 100168123
PHU: 
Phum_PHUM503280
ISC: 
IscW_ISCW001784
CEL: 
CELE_C06A8.4(skr-17) CELE_C42D4.6(skr-16) CELE_C52D10.6(skr-12) CELE_C52D10.7(skr-9) CELE_C52D10.8(skr-13) CELE_C52D10.9(skr-8) CELE_F44G3.6(skr-3) CELE_F46A9.4(skr-2) CELE_F46A9.5(skr-1) CELE_F47H4.10(skr-5) CELE_F54D10.1(skr-15) CELE_F56B3.12(skr-18) CELE_K08H2.1(skr-21) CELE_R12H7.5(skr-20) CELE_Y105C5B.13(skr-10) CELE_Y37H2C.2(skr-6) CELE_Y47D7A.1(skr-7) CELE_Y47D7A.8(skr-14) CELE_Y60A3A.18(skr-4)
CBR: 
CBG00481 CBG00482 CBG00496 CBG02202 CBG02413 CBG03757 CBG03758(Cbr-skr-1) CBG05259(Cbr-skr-20) CBG05260(Cbr-skr-19) CBG05261(Cbr-skr-21) CBG05791(Cbr-skr-16) CBG09040 CBG09125 CBG09126 CBG10989 CBG12957(Cbr-skr-17) CBG12958 CBG14875 CBG14876 CBG15156 CBG18731
BMY: 
Bm1_00275 Bm1_03975
TSP: 
Tsp_10531
SMM: 
Smp_052910
NVE: 
NEMVE_v1g164893
HMG: 
100212686
TAD: 
TRIADDRAFT_34476 TRIADDRAFT_63284
AQU: 
100631812
ATH: 
AT1G10230(SK18) AT1G20140(SK4) AT1G75950(SKP1) AT2G03160(SK19) AT2G03170(SK14) AT2G03190(SK16) AT2G20160(MEO) AT2G25700(SK3) AT3G21830(SK8) AT3G21840(SK7) AT3G21850(SK9) AT3G21860(SK10) AT3G25650(SK15) AT3G53060(SK6) AT3G60010(SK13) AT3G60020(SK5) AT4G34210(SK11) AT4G34470(SK12) AT5G42190(ASK2)
ALY: 
ARALYDRAFT_471136 ARALYDRAFT_481069 ARALYDRAFT_484224 ARALYDRAFT_889462 ARALYDRAFT_899849 ARALYDRAFT_904587 ARALYDRAFT_904588 ARALYDRAFT_907521 ARALYDRAFT_907522 ARALYDRAFT_912943 ARALYDRAFT_917589
GMX: 
100809769
MTR: 
MTR_5g022710 MTR_5g022730
CSV: 
101217906
RCU: 
RCOM_0362150 RCOM_1598810 RCOM_1598820
POP: 
POPTR_813631 POPTR_818827 POPTR_836573
VVI: 
100252349 100257179 100267502
OSA: 
4339908 4343000 4343962 4343963 4345419 4346585 4346586 4346592 4347721 4348713 9270098
DOSA: 
Os06t0113800-00(Os06g0113800) Os07t0409500-01(Os07g0409500) Os07t0625400-01(Os07g0625400) Os07t0625500-01(Os07g0625500) Os08t0375700-00(Os08g0375700) Os09t0273800-01(Os09g0273800) Os09t0275200-01(Os09g0275200) Os09t0539500-01(Os09g0539500) Os10t0438100-00(Os10g0438100) Os11t0456300-01(Os11g0456300)
BDI: 
100822759 100826905 100843377
SBI: 
SORBI_01g021160(SORBIDRAFT_01g021160) SORBI_04g000330(SORBIDRAFT_04g000330) SORBI_05g012740(SORBIDRAFT_05g012740)
ZMA: 
100193107 100280388
SMO: 
SELMODRAFT_154042(SKP1-2) SELMODRAFT_271223(SKP1-1)
PPP: 
PHYPADRAFT_104499 PHYPADRAFT_136643 PHYPADRAFT_159093 PHYPADRAFT_56938 PHYPADRAFT_70480
CRE: 
CHLREDRAFT_128004(SKP1)
VCN: 
VOLCADRAFT_73445
OLU: 
OSTLU_28570
CME: 
CMP118C
SCE: 
YDR328C(SKP1)
AGO: 
AGOS_ADR295C
ERC: 
Ecym_8162
KLA: 
KLLA0E16941g
LTH: 
KLTH0E03784g
PPA: 
PAS_chr3_1258
VPO: 
Kpol_1055p6
ZRO: 
ZYRO0D10384g
CGR: 
CAGL0M01364g
NCS: 
NCAS_0F02970(NCAS0F02970)
NDI: 
NDAI_0C04420(NDAI0C04420)
TPF: 
TPHA_0D02190(TPHA0D02190)
TBL: 
TBLA_0H01860(TBLA0H01860)
TDL: 
TDEL_0E02570(TDEL0E02570)
KAF: 
KAFR_0D04400(KAFR0D04400)
DHA: 
DEHA2F26004g
PIC: 
PICST_32591
PGU: 
PGUG_03114
LEL: 
LELG_00846
CAL: 
CaO19.11905(SKP1) CaO19.4427(SKP1)
CTP: 
CTRG_04163
CDU: 
CD36_06920
COT: 
CORT_0A07830
YLI: 
YALI0A10879g
CLU: 
CLUG_05863
NCR: 
NCU08991
SMP: 
SMAC_01944
PAN: 
PODANSg5136
TTT: 
THITE_2170929
MTM: 
MYCTH_2315211
MGR: 
MGG_04978
FGR: 
FG06922.1
NHE: 
NECHADRAFT_100118
VAL: 
VDBG_06727
SSL: 
SS1G_00543
BFU: 
BC1G_01973 BC1G_01974
ANI: 
AN2302.2
NFI: 
NFIA_037050
AFM: 
AFUA_5G06060
AOR: 
AOR_1_1098184(AO090009000653)
AFV: 
AFLA_048530
ACT: 
ACLA_009360
CIM: 
CIMG_06200
CPW: 
CPC735_027450
PBL: 
PAAG_07339
URE: 
UREG_04186
ABE: 
ARB_06761
AJE: 
HCAG_03008
PNO: 
SNOG_09332
PTE: 
PTT_18813
ZTR: 
MYCGRDRAFT_105450
TML: 
GSTUM_00006439001
SPO: 
SPBC409.05(skp1)
CNE: 
CNA08080
CNB: 
CNBA7900
CGI: 
CGB_A9450C
PPL: 
POSPLDRAFT_134908
LBC: 
LACBIDRAFT_192726
MPR: 
MPER_11341
CCI: 
CC1G_01011
SCM: 
SCHCODRAFT_66042
UMA: 
UM04611.1
MGL: 
MGL_3474
PGR: 
PGTG_17023
ECU: 
ECU03_0300
EIN: 
Eint_030190
EHE: 
EHEL_030180
NCE: 
NCER_101491
MBR: 
MONBRDRAFT_31689
NGR: 
NAEGRDRAFT_82963
DDI: 
DDB_G0269230(fpaA) DDB_G0273251(fpaB-1) DDB_G0273615(fpaB-2)
DPP: 
DICPUDRAFT_97089
EHI: 
EHI_065310 EHI_066770(181.t00006) EHI_118670(62.t00027) EHI_134960(153.t00018) EHI_174130(116.t00012) EHI_174180(116.t00016)
EDI: 
EDI_018360 EDI_159050 EDI_228910
PFA: 
MAL13P1.337
PFD: 
PFDG_04304
PFH: 
PFHG_04146
PYO: 
PY00081
PCB: 
PC000640.04.0
PBE: 
PB000001.03.0
PKN: 
PKH_110350
PVX: 
PVX_115310
PCY: 
PCYB_111350
TAN: 
TA03425
TPV: 
TP03_0225
BBO: 
BBOV_IV006860(23.m05921)
CPV: 
cgd7_2500
TGO: 
TGME49_007680
TET: 
TTHERM_00426320 TTHERM_00469400 TTHERM_01013330
PTM: 
GSPATT00005066001 GSPATT00017523001 GSPATT00021269001 GSPATT00030863001 GSPATT00038211001
TBR: 
Tb11.02.3990
TCR: 
506297.350 508041.10
LMA: 
LMJF_11_1210
LIF: 
LINJ_11_1200
LDO: 
LDBPK_111200
LMI: 
LMXM_11_1210
LBZ: 
LBRM_11_0950
GLA: 
GL50803_2509
TVA: 
TVAG_098740
PTI: 
PHATRDRAFT_17276(Skp1_1)
TPS: 
THAPSDRAFT_10077 THAPSDRAFT_38460
PIF: 
PITG_01260 PITG_15216
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Petroski MD, Deshaies RJ.
  Title
Function and regulation of cullin-RING ubiquitin ligases.
  Journal
Nat Rev Mol Cell Biol 6:9-20 (2005)
Reference
  Authors
Jin J, Cardozo T, Lovering RC, Elledge SJ, Pagano M, Harper JW.
  Title
Systematic analysis and nomenclature of mammalian F-box proteins.
  Journal
Genes Dev 18:2573-80 (2004)
Reference
  Authors
Gillis AN, Thomas S, Hansen SD, Kaplan KB
  Title
A novel role for the CBF3 kinetochore-scaffold complex in regulating septin dynamics and cytokinesis.
  Journal
J Cell Biol 171:773-84 (2005)
DBGET integrated database retrieval system