KEGG ORTHOLOGY: K03347

ORTHOLOGY: K03347

Entry

K03347 KO

Name

CUL1, CDC53

Definition

cullin 1

Pathway

ko04110	Cell cycle
ko04111	Cell cycle - yeast
ko04114	Oocyte meiosis
ko04120	Ubiquitin mediated proteolysis
ko04141	Protein processing in endoplasmic reticulum
ko04310	Wnt signaling pathway
ko04350	TGF-beta signaling pathway
ko04710	Circadian rhythm
ko05168	Herpes simplex infection

Module

M00379	SCF-MET30 complex
M00380	SCF-BTRC complex
M00381	SCF-SKP2 complex
M00382	SCF-FBS complex
M00387	SCF-FBW7 complex
M00407	SCF-CDC4 complex
M00411	SCF-GRR1 complex

Brite

KEGG Orthology (KO) [BR:ko00001]
Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K03347  CUL1, CDC53; cullin 1
   04120 Ubiquitin mediated proteolysis
    K03347  CUL1, CDC53; cullin 1
Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    K03347  CUL1, CDC53; cullin 1
   04350 TGF-beta signaling pathway
    K03347  CUL1, CDC53; cullin 1
Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K03347  CUL1, CDC53; cullin 1
   04111 Cell cycle - yeast
    K03347  CUL1, CDC53; cullin 1
   04114 Oocyte meiosis
    K03347  CUL1, CDC53; cullin 1
Organismal Systems
  Environmental adaptation
   04710 Circadian rhythm
    K03347  CUL1, CDC53; cullin 1
Human Diseases
  Infectious diseases
   05168 Herpes simplex infection
    K03347  CUL1, CDC53; cullin 1
KEGG pathway modules [BR:ko00002]
Structural complex
  Genetic information processing
   Ubiquitin system
    M00379  SCF-MET30 complex [BR:ko04121]
     K03347  CUL1, CDC53; cullin 1
    M00380  SCF-BTRC complex [BR:ko04121]
     K03347  CUL1, CDC53; cullin 1
    M00381  SCF-SKP2 complex [BR:ko04121]
     K03347  CUL1, CDC53; cullin 1
    M00382  SCF-FBS complex [BR:ko04121]
     K03347  CUL1, CDC53; cullin 1
    M00407  SCF-CDC4 complex [BR:ko04121]
     K03347  CUL1, CDC53; cullin 1
    M00411  SCF-GRR1 complex [BR:ko04121]
     K03347  CUL1, CDC53; cullin 1
    M00387  SCF-FBW7 complex [BR:ko04121]
     K03347  CUL1, CDC53; cullin 1
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  multi subunit Ring-finger type E3
   SCF complex
    Cullin
     K03347  CUL1, CDC53; cullin 1

Other DBs

COG:

COG5647

Genes

HSA:	8454(CUL1)
PTR:	463821(CUL1)
PPS:	100972042(CUL1)
GGO:	101152264
PON:	100173991(CUL1)
MCC:	710581(CUL1)
MMU:	26965(Cul1)
RNO:	362356(Cul1)
CFA:	475512(CUL1)
AML:	100466596
FCA:	101087051(CUL1)
BTA:	407228(CUL1)
SSC:	100524037
ECB:	100051217
MDO:	100013348
SHR:	100926417(CUL1)
OAA:	100073945
GGA:	420783(CUL1)
MGP:	100540218
TGU:	100223849(CUL1)
ACS:	100563024
XLA:	734414(cul1) 734526
XTR:	734121(cul1)
DRE:	323883(cul1a) 406816(cul1b)
TRU:	101068951
OLA:	101155471
BFO:	BRAFLDRAFT_123717
CIN:	100177902
SPU:	589630
DME:	Dmel_CG1877(lin19)
DPO:	Dpse_GA15074
DAN:	Dana_GF13641
DER:	Dere_GG23311
DPE:	Dper_GL11695
DSE:	Dsec_GM20989
DSI:	Dsim_GD10516
DWI:	Dwil_GK21971
DYA:	Dyak_GE19156
DGR:	Dgri_GH21298
DMO:	Dmoj_GI19786
DVI:	Dvir_GJ17750
AGA:	AgaP_AGAP008007
AAG:	AaeL_AAEL013530
CQU:	CpipJ_CPIJ003090
AME:	410565
NVI:	100123219(CUL1)
TCA:	660670
API:	100160902
PHU:	Phum_PHUM207700 Phum_PHUM546660
ISC:	IscW_ISCW013256
CEL:	CELE_D2045.6(cul-1)
CBR:	CBG18382(Cbr-cul-1)
BMY:	Bm1_21420
TSP:	Tsp_02228
SMM:	Smp_150270
NVE:	NEMVE_v1g189228
HMG:	100206949(cul1)
TAD:	TRIADDRAFT_37264
AQU:	100638896(Cul1)
ATH:	AT1G02980(CUL2) AT1G43140 AT1G59790 AT1G59800 AT4G02570(CUL1)
ALY:	ARALYDRAFT_311398 ARALYDRAFT_338392 ARALYDRAFT_338401 ARALYDRAFT_893577 ARALYDRAFT_893578 ARALYDRAFT_893584 ARALYDRAFT_911957 ARALYDRAFT_916450
GMX:	100778287 100779134 100784626 100786561 100793682 100819650
MTR:	MTR_7g108340
CSV:	101216323
RCU:	RCOM_0680540 RCOM_1680770
POP:	POPTR_711781 POPTR_725818 POPTR_828007
VVI:	100233054(CUL1) 100261361
OSA:	4325735 4325736 4337820
DOSA:	Os01t0369000-01(Os01g0369000) Os01t0369200-01(Os01g0369200)
BDI:	100824498 100824990 100825090
SBI:	SORBI_03g015000(SORBIDRAFT_03g015000) SORBI_03g015010(SORBIDRAFT_03g015010) SORBI_09g003820(SORBIDRAFT_09g003820)
SMO:	SELMODRAFT_158171(CUL1-2) SELMODRAFT_173394(CUL1-1)
PPP:	PHYPADRAFT_107536 PHYPADRAFT_167405 PHYPADRAFT_192315
CRE:	CHLREDRAFT_116937(CUL3)
VCN:	VOLCADRAFT_108919
OLU:	OSTLU_50090
OTA:	Ot07g00170
SCE:	YDL132W(CDC53)
AGO:	AGOS_ADR106W
ERC:	Ecym_8046
KLA:	KLLA0F05467g
LTH:	KLTH0H02464g
PPA:	PAS_chr1-1_0312
VPO:	Kpol_2000p10
ZRO:	ZYRO0C09438g
CGR:	CAGL0J09218g
NCS:	NCAS_0A13810(NCAS0A13810)
NDI:	NDAI_0A02230(NDAI0A02230)
TPF:	TPHA_0P00850(TPHA0P00850)
TBL:	TBLA_0A05930(TBLA0A05930)
TDL:	TDEL_0H01480(TDEL0H01480)
KAF:	KAFR_0B01150(KAFR0B01150)
DHA:	DEHA2D15444g
PIC:	PICST_29770(CDC53)
PGU:	PGUG_00569
LEL:	LELG_02231
CAL:	CaO19.1674(CDC53) CaO19.9243(CDC53)
CTP:	CTRG_02143
CDU:	CD36_81580
COT:	CORT_0D06720
YLI:	YALI0D12518g
CLU:	CLUG_01999
NCR:	NCU05204
SMP:	SMAC_07196
PAN:	PODANSg3750
TTT:	THITE_2122761
MTM:	MYCTH_2309854
MGR:	MGG_07145
FGR:	FG09616.1
NHE:	NECHADRAFT_103491
VAL:	VDBG_04363
SSL:	SS1G_07592
BFU:	BC1G_03004
ANI:	AN1019.2
NFI:	NFIA_012590
AFM:	AFUA_1G12960
AOR:	AOR_1_1040194(AO090012000597)
ANG:	ANI_1_830074(An08g05870)
AFV:	AFLA_018520
ACT:	ACLA_022500
PCS:	Pc13g11700
CIM:	CIMG_05917
CPW:	CPC735_025200
PBL:	PAAG_00533
URE:	UREG_04430
ABE:	ARB_01462
TVE:	TRV_05741
AJE:	HCAG_08456
PNO:	SNOG_13309
PTE:	PTT_04953
ZTR:	MYCGRDRAFT_76524
TML:	GSTUM_00002124001
SPO:	SPAC17G6.12(cul1)
CNE:	CNN01140
CNB:	CNBN1130
CGI:	CGB_N1540W
LBC:	LACBIDRAFT_183083 LACBIDRAFT_245059
MPR:	MPER_02436 MPER_03317
CCI:	CC1G_03473 CC1G_10644
SCM:	SCHCODRAFT_46496 SCHCODRAFT_66727
UMA:	UM01087.1
MGL:	MGL_2715
PGR:	PGTG_17202
MBR:	MONBRDRAFT_34736
NGR:	NAEGRDRAFT_81152
DDI:	DDB_G0291972(culA)
DPP:	DICPUDRAFT_44981
EHI:	EHI_156450(100.t00027)
EDI:	EDI_007960
PFH:	PFHG_02564
PBE:	PB001422.02.0
PVX:	PVX_123220
TGO:	TGME49_089310
PTM:	GSPATT00037059001
PTI:	PHATRDRAFT_29317(CUL1_3)
TPS:	THAPSDRAFT_267964
PIF:	PITG_02724 PITG_03075

» show all

Reference

PMID:15688063

Authors

Petroski MD, Deshaies RJ.

Title

Function and regulation of cullin-RING ubiquitin ligases.

Journal

Nat Rev Mol Cell Biol 6:9-20 (2005)

Reference

PMID:15520277

Authors

Jin J, Cardozo T, Lovering RC, Elledge SJ, Pagano M, Harper JW.

Title

Systematic analysis and nomenclature of mammalian F-box proteins.

Journal

Genes Dev 18:2573-80 (2004)

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Ontology (4)   
   KEGG BRITE (3)   
   COG (1)   
Pathway (436)   
   KEGG PATHWAY (18)   
   KEGG MODULE (418)   
Gene (788)   
   KEGG GENES (196)   
   KEGG DGENES (31)   
   KEGG EGENES (447)   
   KEGG MGENES (114)   
Protein sequence (170)   
   UniProt (170)   
Literature (2)   
   PubMed (2)   
All databases (1400)   

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