KEGG   ORTHOLOGY: K04102Help
Entry
K04102                      KO                                     

Name
pht5
Definition
4,5-dihydroxyphthalate decarboxylase [EC:4.1.1.55]
Pathway
Polycyclic aromatic hydrocarbon degradation
Module
M00623  
Phthalate degradation, phthalate => protocatechuate
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Xenobiotics biodegradation and metabolism
   00624 Polycyclic aromatic hydrocarbon degradation
    K04102  pht5; 4,5-dihydroxyphthalate decarboxylase
KEGG modules [BR:ko00002]
 Pathway module
  Secondary metabolism
   Aromatics degradation
    M00623  Phthalate degradation, phthalate => protocatechuate
     K04102  pht5; 4,5-dihydroxyphthalate decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.55  4,5-dihydroxyphthalate decarboxylase
     K04102  pht5; 4,5-dihydroxyphthalate decarboxylase
BRITE hierarchy
Other DBs
Genes
HAM: 
RPF: 
CNC: 
CCUP: 
BVI: 
BCEN: 
BMU: 
BMK: 
BYI: 
BUO: 
BUE: 
BRPE67_BCDS04060 BRPE67_DCDS10030 BRPE67_DCDS10120
BXE: 
Bxe_A2046
BXB: 
DR64_4202
BPY: 
Bphyt_2225
BFN: 
OI25_6506
BCAI: 
K788_0001936 K788_0002080 K788_0006051 K788_0006973
PSPW: 
BJG93_04710 BJG93_19295
PNR: 
AT302_26805
BPE: 
BP0683
BPC: 
BPTD_0690
BPER: 
BN118_3023
BPET: 
B1917_0469
BPEU: 
Q425_4290
BPA: 
BPP0387
BPAR: 
BN117_0384
BBR: 
BB0389
BBM: 
BN115_0374
BBH: 
BN112_3024
BBX: 
BBS798_0385
BPT: 
Bpet0251
BAV: 
BAV0612(phtD)
BHZ: 
ACR54_04438(pht5)
BBRO: 
BAU06_03755
BFZ: 
BAU07_03955 BAU07_15860
CDN: 
BN940_06901
AFA: 
UZ73_14455
RHY: 
RD110_17805 RD110_25750
POL: 
Bpro_1912
PNA: 
Pnap_4626
ACID: 
CBP33_05525
VEI: 
Veis_2927
DEL: 
DelCs14_1656
CTT: 
CtCNB1_1485
CTES: 
O987_21860
LIM: 
L103DPR2_01692(pht5_1) L103DPR2_02564(pht5_2) L103DPR2_02571(pht5_3)
HYR: 
BSY239_3463
MASW: 
AM586_26805 AM586_27415 AM586_27620 AM586_27685
MES: 
Meso_0812
RHT: 
NT26_0606(phtD)
BVV: 
BHK69_01795
PHL: 
KKY_2552
RHZ: 
RHPLAN_02150 RHPLAN_05430 RHPLAN_08180 RHPLAN_09020 RHPLAN_09030 RHPLAN_10250 RHPLAN_10400 RHPLAN_10470 RHPLAN_21070 RHPLAN_23490 RHPLAN_27380 RHPLAN_27510 RHPLAN_30440 RHPLAN_33070 RHPLAN_33370 RHPLAN_34990 RHPLAN_47510 RHPLAN_59590 RHPLAN_64790 RHPLAN_68290
MMED: 
Mame_05093(pht5)
PSIN: 
CAK95_02200 CAK95_15630 CAK95_24720
BRL: 
BZG35_10665
CBOT: 
ATE48_17510
CID: 
P73_2964
TPRO: 
Ga0080559_TMP5107
PABY: 
Ga0080574_TMP2099 Ga0080574_TMP339
SPHR: 
BSY17_4180 BSY17_4184
RGI: 
RGI145_16725 RGI145_21160
PGV: 
SL003B_1108
PNP: 
IJ22_14400 IJ22_32350
PYG: 
AWM70_00715
FRP: 
AX769_17105
ARZ: 
AUT26_02345
AMO: 
Anamo_1078
AG: 
BAA02513(pht5)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Nomura Y, Nakagawa M, Ogawa N, Harashima S, Oshima Y
  Title
Genes in PHT plasmid encoding the initial degradation pathway of phthalate in Pseudomonas putida.
  Journal
J Ferment Bioeng 74:333-344 (1992)
DOI:10.1016/0922-338X(92)90028-S
  Sequence
LinkDB All DBs

KEGG   ENZYME: 4.1.1.55Help
Entry
EC 4.1.1.55                 Enzyme                                 

Name
4,5-dihydroxyphthalate decarboxylase;
4,5-dihydroxyphthalate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)
Reaction(IUBMB)
4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2 [RN:R01635]
Reaction(KEGG)
R01635;
(other) R05375
Show
Substrate
4,5-dihydroxyphthalate [CPD:C03233]
Product
3,4-dihydroxybenzoate [CPD:C00230];
CO2 [CPD:C00011]
History
EC 4.1.1.55 created 1972
Pathway
Polycyclic aromatic hydrocarbon degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K04102  
4,5-dihydroxyphthalate decarboxylase
Genes
HAM: 
RPF: 
CNC: 
CCUP: 
BVI: 
BCEN: 
BMU: 
BMK: 
BYI: 
BUO: 
BUE: 
BRPE67_BCDS04060 BRPE67_DCDS10030 BRPE67_DCDS10120
BXE: 
Bxe_A2046
BXB: 
DR64_4202
BPY: 
Bphyt_2225
BFN: 
OI25_6506
BCAI: 
K788_0001936 K788_0002080 K788_0006051 K788_0006973
PSPW: 
BJG93_04710 BJG93_19295
PNR: 
AT302_26805
BPE: 
BP0683
BPC: 
BPTD_0690
BPER: 
BN118_3023
BPET: 
B1917_0469
BPEU: 
Q425_4290
BPA: 
BPP0387
BPAR: 
BN117_0384
BBR: 
BB0389
BBM: 
BN115_0374
BBH: 
BN112_3024
BBX: 
BBS798_0385
BPT: 
Bpet0251
BAV: 
BAV0612(phtD)
BHZ: 
ACR54_04438(pht5)
BBRO: 
BAU06_03755
BFZ: 
BAU07_03955 BAU07_15860
CDN: 
BN940_06901
AFA: 
UZ73_14455
RHY: 
RD110_17805 RD110_25750
POL: 
Bpro_1912
PNA: 
Pnap_4626
ACID: 
CBP33_05525
VEI: 
Veis_2927
DEL: 
DelCs14_1656
CTT: 
CtCNB1_1485
CTES: 
O987_21860
LIM: 
L103DPR2_01692(pht5_1) L103DPR2_02564(pht5_2) L103DPR2_02571(pht5_3)
HYR: 
BSY239_3463
MASW: 
AM586_26805 AM586_27415 AM586_27620 AM586_27685
MES: 
Meso_0812
RHT: 
NT26_0606(phtD)
BVV: 
BHK69_01795
PHL: 
KKY_2552
RHZ: 
RHPLAN_02150 RHPLAN_05430 RHPLAN_08180 RHPLAN_09020 RHPLAN_09030 RHPLAN_10250 RHPLAN_10400 RHPLAN_10470 RHPLAN_21070 RHPLAN_23490 RHPLAN_27380 RHPLAN_27510 RHPLAN_30440 RHPLAN_33070 RHPLAN_33370 RHPLAN_34990 RHPLAN_47510 RHPLAN_59590 RHPLAN_64790 RHPLAN_68290
MMED: 
Mame_05093(pht5)
PSIN: 
CAK95_02200 CAK95_15630 CAK95_24720
BRL: 
BZG35_10665
CBOT: 
ATE48_17510
CID: 
P73_2964
TPRO: 
Ga0080559_TMP5107
PABY: 
Ga0080574_TMP2099 Ga0080574_TMP339
SPHR: 
BSY17_4180 BSY17_4184
RGI: 
RGI145_16725 RGI145_21160
PGV: 
SL003B_1108
PNP: 
IJ22_14400 IJ22_32350
PYG: 
AWM70_00715
FRP: 
AX769_17105
ARZ: 
AUT26_02345
AMO: 
Anamo_1078
 » show all
Taxonomy
Reference
1  [PMID:16748829]
  Authors
Ribbons DW, Evans WC.
  Title
Oxidative metabolism of phthalic acid by soil pseudomonads.
  Journal
Biochem. J. 76 (1960) 310-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
37290-48-5
LinkDB All DBs

KEGG   REACTION: R01635Help
Entry
R01635                      Reaction                               

Name
4,5-Dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)
Definition
4,5-Dihydroxyphthalate <=> 3,4-Dihydroxybenzoate + CO2
Equation
Reaction class
C00230_C03233
Enzyme
Pathway
Polycyclic aromatic hydrocarbon degradation
Metabolic pathways
Microbial metabolism in diverse environments
Module
M00623  
Phthalate degradation, phthalate => protocatechuate
Orthology
K04102  
4,5-dihydroxyphthalate decarboxylase [EC:4.1.1.55]
Other DBs
RHEA: 
LinkDB All DBs

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