KEGG ORTHOLOGY: K05708

ORTHOLOGY: K05708

Entry

K05708 KO

Name

hcaE, hcaA1

Definition

3-phenylpropionate/trans-cinnamate dioxygenase subunit alpha [EC:1.14.12.19]

Pathway

ko00360	Phenylalanine metabolism
ko01220	Degradation of aromatic compounds

Module

M00545

Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Overview
   01220 Degradation of aromatic compounds
    K05708  hcaE, hcaA1; 3-phenylpropionate/trans-cinnamate dioxygenase subunit alpha
  Amino acid metabolism
   00360 Phenylalanine metabolism
    K05708  hcaE, hcaA1; 3-phenylpropionate/trans-cinnamate dioxygenase subunit alpha
KEGG modules [BR:ko00002]
Pathway module
  Nucleotide and amino acid metabolism
   Aromatic amino acid metabolism
    M00545  Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
     K05708  hcaE, hcaA1; 3-phenylpropionate/trans-cinnamate dioxygenase subunit alpha
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.19  3-phenylpropanoate dioxygenase
     K05708  hcaE, hcaA1; 3-phenylpropionate/trans-cinnamate dioxygenase subunit alpha

Other DBs

RN:

R06782 R06783

COG:

COG4638

GO:

0008695

Genes

ECO:	b2538(hcaE)
ECJ:	JW2522(hcaE)
ECD:	ECDH10B_2705(hcaE)
EBW:	BWG_2302(hcaE)
ECOK:	ECMDS42_2082(hcaE)
ECE:	Z3809(hcaA1)
ECS:	ECs3404
ETW:	ECSP_3482(hcaE)
ELX:	CDCO157_3171
EOJ:	ECO26_3585(hcaE)
EOI:	ECO111_3262(hcaE)
EOH:	ECO103_3055(hcaE)
EOK:	G2583_3068(hcaE)
ELR:	ECO55CA74_15185
ECX:	EcHS_A2690(hcaE)
ECM:	EcSMS35_2691(hcaE)
ECY:	ECSE_2825
ECR:	ECIAI1_2590(hcaE)
ECK:	EC55989_2824(hcaE)
ECT:	ECIAI39_2739(hcaE)
EOC:	CE10_2970(hcaE)
EUM:	ECUMN_2858(hcaE)
ELO:	EC042_2742(hcaE)
ELH:	ETEC_2695
ESO:	O3O_18925
ESM:	O3M_06770
ESL:	O3K_06725
ECL:	EcolC_1139
EBR:	ECB_02430(hcaE)
EBD:	ECBD_1146
EKO:	EKO11_1195
EKF:	KO11_10130(hcaE)
EDH:	EcDH1_1130
EDJ:	ECDH1ME8569_2465(hcaE)
EUN:	UMNK88_3191
ELW:	ECW_m2764(hcaE)
ELL:	WFL_13535(hcaE)
ELP:	P12B_c2638(hcaA)
EBL:	ECD_02430(hcaE)
EBE:	B21_02394(hcaE)
ECOA:	APECO78_16420
ECOL:	LY180_13020
ECOO:	ECRM13514_3370(hcaA1)
ECOH:	ECRM13516_3226(hcaA1)
SFL:	SF2585(hcaA1)
SFX:	S2757(hcaA1)
SFV:	SFV_2586(hcaA1)
SFE:	SFxv_2841(hcaE)
SFN:	SFy_3672
SFS:	SFyv_3749
SFT:	NCTC1_02841(hcaA1)
SSN:	SSON_2620(hcaA1)
SBO:	SBO_2562(hcaA1)
SHQ:	A0259_16415
KPV:	KPNIH29_19720
CFD:	CFNIH1_24125
CIF:	AL515_17210
EBF:	D782_1131
SFW:	WN53_15140
SFG:	AV650_10680
PLU:	plu2204(hcaE)
PAY:	PAU_02357(hcaE)
PTT:	VY86_20040
VNA:	PN96_06440
VEJ:	VEJY3_06610
VFU:	vfu_A01965
AEI:	AOY20_01950
ASJ:	AsACE_CH00358(hcaE)
CYQ:	Q91_0870 Q91_2056 Q91_2174
CZA:	CYCME_0248 CYCME_0369
GBI:	PG2T_03650 PG2T_10655 PG2T_14655
AQL:	BXU06_16235
BCEN:	DM39_1983
BDF:	WI26_30250
BPLA:	bpln_1g12620
AFA:	UZ73_04210
DEL:	DelCs14_1743
RBU:	PG1C_02395
NAR:	Saro_3840
NPP:	PP1Y_AT31297
SPHP:	LH20_03925
SWI:	Swit_0890
AAY:	WYH_01869(hcaE)
MSA:	Mycsm_01912 Mycsm_01988
MVA:	Mvan_4415
MAB:	MAB_4370c
MAY:	LA62_22205
MABO:	NF82_21895
MAZ:	LA61_22100
MFT:	XA26_16860
CDR:	CDHC03_1952(hcaE)
CAZ:	CARG_03210 CARG_03270
CII:	CIMIT_11730
CMV:	CMUST_15080(hcaE)
NFR:	ERS450000_00303(hcaE_2)
NNO:	NONO_c29020
REB:	XU06_31885
REQ:	REQ_35060
RAV:	AAT18_09365
GOR:	KTR9_1265
DTM:	BJL86_0371
SCB:	SCAB_2191(hcaE)
STSI:	A4E84_36430
MIO:	AOA12_18550
NAE:	BHE16_09185
FRI:	FraEuI1c_4097
TRO:	trd_A0341
SAI:	Saci_2059
SACR:	SacRon12I_10260
SACS:	SUSAZ_05365 SUSAZ_09335
SIS:	LS215_0748
SIA:	M1425_0846
SIM:	M1627_0911
SID:	M164_0864
SIY:	YG5714_0780
SII:	LD85_0977
SIH:	SiH_0732

» show all

Reference

PMID:9603882

Authors

Diaz E, Ferrandez A, Garcia JL.

Title

Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.

Journal

J Bacteriol 180:2915-23 (1998)

Sequence

[eco:b2538]

LinkDB

ORTHOLOGY: K05709

Entry

K05709 KO

Name

hcaF, hcaA2

Definition

3-phenylpropionate/trans-cinnamate dioxygenase subunit beta [EC:1.14.12.19]

Pathway

ko00360	Phenylalanine metabolism
ko01220	Degradation of aromatic compounds

Module

M00545

Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Overview
   01220 Degradation of aromatic compounds
    K05709  hcaF, hcaA2; 3-phenylpropionate/trans-cinnamate dioxygenase subunit beta
  Amino acid metabolism
   00360 Phenylalanine metabolism
    K05709  hcaF, hcaA2; 3-phenylpropionate/trans-cinnamate dioxygenase subunit beta
KEGG modules [BR:ko00002]
Pathway module
  Nucleotide and amino acid metabolism
   Aromatic amino acid metabolism
    M00545  Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
     K05709  hcaF, hcaA2; 3-phenylpropionate/trans-cinnamate dioxygenase subunit beta
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.19  3-phenylpropanoate dioxygenase
     K05709  hcaF, hcaA2; 3-phenylpropionate/trans-cinnamate dioxygenase subunit beta

Other DBs

RN:

R06782 R06783

COG:

COG5517

GO:

0008695

Genes

ECO:	b2539(hcaF)
ECJ:	JW2523(hcaF)
ECD:	ECDH10B_2706(hcaF)
EBW:	BWG_2303(hcaF)
ECOK:	ECMDS42_2083(hcaF)
ECE:	Z3810(hcaA2)
ECS:	ECs3405
ECF:	ECH74115_3771(hcaF)
ETW:	ECSP_3483(hcaF)
ELX:	CDCO157_3172
EOJ:	ECO26_3586(hcaF)
EOI:	ECO111_3263(hcaF)
EOK:	G2583_3069(hcaF)
ELR:	ECO55CA74_15190
ECX:	EcHS_A2691(hcaF)
ECW:	EcE24377A_2824(hcaF)
ECM:	EcSMS35_2692(hcaF)
ECY:	ECSE_2826
ECR:	ECIAI1_2591(hcaF)
ECK:	EC55989_2825(hcaF)
ECT:	ECIAI39_2740(hcaF)
EOC:	CE10_2971(hcaF)
EUM:	ECUMN_2859(hcaF)
ELO:	EC042_2743(hcaF)
ELH:	ETEC_2696
ESO:	O3O_18930
ESM:	O3M_06765
ESL:	O3K_06720
ECL:	EcolC_1138
EBR:	ECB_02431(hcaF)
EBD:	ECBD_1145
EKO:	EKO11_1194
EKF:	KO11_10125(hcaF)
EDH:	EcDH1_1129
EDJ:	ECDH1ME8569_2466(hcaF)
EUN:	UMNK88_3192
ELW:	ECW_m2765(hcaF)
ELL:	WFL_13540(hcaF)
ELP:	P12B_c2639(hcaF)
EBL:	ECD_02431(hcaF)
EBE:	B21_02395(hcaF)
ECOA:	APECO78_16425
ECOL:	LY180_13025
ECOO:	ECRM13514_3371(hcaA2)
ECOH:	ECRM13516_3227(hcaA2)
SFL:	SF2586(hcaA2)
SFX:	S2758(hcaA2)
SFV:	SFV_2587(hcaA2)
SFE:	SFxv_2842(hcaF)
SFN:	SFy_3673
SFS:	SFyv_3750
SFT:	NCTC1_02842(hcaA2)
SSN:	SSON_2621(hcaA2)
SBO:	SBO_2563(hcaA2)
SHQ:	A0259_16420
KPV:	KPNIH29_19725
CFD:	CFNIH1_24130
CIF:	AL515_17215
KGO:	CEW81_06275
EBF:	D782_1130
SFW:	WN53_15145
SFG:	AV650_10685
PLU:	plu2205(hcaF)
PAY:	PAU_02356(hcaF)
PTT:	VY86_20035
VNA:	PN96_06445
VEJ:	VEJY3_06605
VFU:	vfu_A01966
AEI:	AOY20_01945
ASJ:	AsACE_CH00359(hcaF)
WOC:	BA177_04185
GBI:	PG2T_03670 PG2T_11305
AQL:	BXU06_16230
BDF:	WI26_30255
AFA:	UZ73_04215
PNP:	IJ22_07010

» show all

Reference

PMID:9603882

Authors

Diaz E, Ferrandez A, Garcia JL.

Title

Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.

Journal

J Bacteriol 180:2915-23 (1998)

Sequence

[eco:b2539]

LinkDB

ORTHOLOGY: K05710

Entry

K05710 KO

Name

hcaC

Definition

3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component

Pathway

ko00360	Phenylalanine metabolism
ko01220	Degradation of aromatic compounds

Module

M00545

Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Overview
   01220 Degradation of aromatic compounds
    K05710  hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component
  Amino acid metabolism
   00360 Phenylalanine metabolism
    K05710  hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component
KEGG modules [BR:ko00002]
Pathway module
  Nucleotide and amino acid metabolism
   Aromatic amino acid metabolism
    M00545  Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
     K05710  hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component

Other DBs

RN:

R06782 R06783

COG:

COG2146

Genes

ECO:	b2540(hcaC)
ECJ:	JW2524(hcaC)
ECD:	ECDH10B_2707(hcaC)
EBW:	BWG_2304(hcaC)
ECOK:	ECMDS42_2084(hcaC)
ECE:	Z3811(hcaC)
ECS:	ECs3406
ECF:	ECH74115_3772(hcaC)
ETW:	ECSP_3484(hcaC)
ELX:	CDCO157_3173
EOJ:	ECO26_3587(hcaC)
EOI:	ECO111_3264(hcaC)
EOH:	ECO103_3060(hcaC)
EOK:	G2583_3070(hcaC)
ELR:	ECO55CA74_15195
ECX:	EcHS_A2692(hcaC)
ECW:	EcE24377A_2825(hcaC)
ECM:	EcSMS35_2693(hcaC)
ECY:	ECSE_2827
ECR:	ECIAI1_2592(hcaC)
ECK:	EC55989_2826(hcaC)
ECT:	ECIAI39_2741(hcaC)
EOC:	CE10_2972(hcaC)
EUM:	ECUMN_2860(hcaC)
ELO:	EC042_2744(hcaC)
ELH:	ETEC_2697
ESO:	O3O_18935
ESM:	O3M_06760
ESL:	O3K_06715
ECL:	EcolC_1137
EBR:	ECB_02432(hcaC)
EBD:	ECBD_1144
EKO:	EKO11_1193
EKF:	KO11_10120(hcaC)
EDH:	EcDH1_1128
EDJ:	ECDH1ME8569_2467(hcaC)
EUN:	UMNK88_3193
ELW:	ECW_m2766(hcaC)
ELL:	WFL_13545(hcaC)
ELP:	P12B_c2640(hcaC)
EBL:	ECD_02432(hcaC)
EBE:	B21_02396(hcaC)
ECOA:	APECO78_16430
ECOL:	LY180_13030
ECOO:	ECRM13514_3372
ECOH:	ECRM13516_3228(hcaC)
SFL:	SF2587(hcaC)
SFX:	S2759(hcaC)
SFV:	SFV_2588(hcaC)
SFE:	SFxv_2843(hcaC)
SFN:	SFy_3674
SFS:	SFyv_3751
SFT:	NCTC1_02843(hcaC)
SSN:	SSON_2622(hcaC)
SBO:	SBO_2564(hcaC)
SHQ:	A0259_16425
KPV:	KPNIH29_19730
CFD:	CFNIH1_24135
CIF:	AL515_17220
KGO:	CEW81_06270
EBF:	D782_1129
SFW:	WN53_15150
SFG:	AV650_10690
PLU:	plu2206(hcaC)
PAY:	PAU_02355(hcaC)
PTT:	VY86_20030
XFA:	XF_1472
XFT:	PD_0689(bedB)
XFM:	Xfasm12_0814
XFN:	XfasM23_0725
XFF:	XFLM_09040
XFL:	P303_03380
XFS:	D934_04985
XFH:	XFHB_04230
XCC:	XCC2771(bedB)
XCB:	XC_1342
XCA:	xcc-b100_1390
XCP:	XCR_3136
XCV:	XCV3084
XAC:	XAC2940(bedB)
XCI:	XCAW_03218(hcaA1)
XCT:	J151_03125
XCU:	J159_03100
XCN:	J169_03123
XCW:	J162_03104
XCR:	J163_03100
XCM:	J164_03100
XCF:	J172_03116
XCJ:	J158_03104
XFU:	XFF4834R_chr16990
XAX:	XACM_2871
XAO:	XAC29_14950
XOO:	XOO1400(bedB)
XOM:	XOO1283(XOO1283)
XOP:	PXO_01974
XOY:	AZ54_17480
XOR:	XOC_1470
XOZ:	BE73_16065
XAL:	XALC_1025(hcaC)
XSA:	SB85_19320
XTN:	FD63_12980
XFR:	BER92_13520
XGA:	BI317_14980
XVE:	BJD12_05580
XPE:	BJD13_01940
SML:	Smlt1150
SMT:	Smal_0994
BUJ:	BurJV3_0988
SMZ:	SMD_1072
SACZ:	AOT14_27020
STEK:	AXG53_12145
SRH:	BAY15_1145
SLM:	BIZ42_14290
PSU:	Psesu_1094
PSUW:	WQ53_13610
PSD:	DSC_05780
LAB:	LA76x_1616(bnzC)
LAQ:	GLA29479_659(bnzC)
LCP:	LC55x_1397(bnzC)
LGU:	LG3211_1294(bnzC)
LEZ:	GLE_1254(bnzC)
LEM:	LEN_3676(hcaC)
FAU:	Fraau_1545
RHD:	R2APBS1_1082
DJI:	CH75_02845
DJA:	HY57_08845
DTX:	ATSB10_17600
DKO:	I596_1872
LRZ:	BJI69_02645
VNA:	PN96_06450
VEJ:	VEJY3_06600
VFU:	vfu_A01967
VNI:	VIBNI_B2031
PRE:	PCA10_24020 PCA10_37160
PALC:	A0T30_12290
PPF:	Pput_2672
PPG:	PputGB1_2815
PSP:	PSPPH_2340
PCI:	PCH70_21500
PFS:	PFLU_2391
PFC:	PflA506_2266
PFW:	PF1751_v1c20820
PFB:	VO64_5561
PFF:	PFLUOLIPICF726300
PPZ:	H045_07310
PMAN:	OU5_5720
PTV:	AA957_02870
PAZO:	AYR47_18695
PPUU:	PputUW4_00898
PDR:	H681_12740 H681_14480
PSK:	U771_12625
PKC:	PKB_3013
PFZ:	AV641_09995 AV641_11815
PALK:	PSAKL28_26180
PPSY:	AOC04_06865
PFK:	PFAS1_22985
PUR:	AOC03_11570
ACC:	BDGL_001694
ANO:	RR32_06810
ACD:	AOLE_06115
ATT:	AMQ28_00950
AEI:	AOY20_01940
ACW:	A0J50_06070
ASJ:	AsACE_CH00360(hcaC)
PTN:	PTRA_a0477
PIN:	Ping_1502
TTU:	TERTU_1277
OSG:	BST96_03565
MCA:	MCA0987
MMT:	Metme_1234
MDN:	JT25_017480
MDH:	AYM39_12360
MAH:	MEALZ_2007(bphF)
MPSY:	CEK71_00210
ALV:	Alvin_0689
TVI:	Thivi_0845
TMB:	Thimo_2705
MPUR:	MARPU_13505
TKM:	TK90_1586
TNI:	TVNIR_1838(hcaC_[H])
TTI:	THITH_07310
TVR:	TVD_05020
HNA:	Hneap_1197
HAZ:	A9404_02060
MARS:	A8C75_03255
SDF:	ACG33_11010
TBN:	TBH_C1582
GPB:	HDN1F_12450
ENM:	EBS_1534(hcaC)
PSE:	NH8B_2003 NH8B_2175
AQL:	BXU06_16225
RSC:	RCFBP_20191
RSL:	RPSI07_2127
RSN:	RSPO_c02125(nagAb)
RPJ:	N234_24840 N234_30475
REU:	Reut_A1482 Reut_B3778
REH:	H16_B0803(h16_B0803) H16_B1518(sufR)
CNC:	CNE_2c07510 CNE_2c15200(sufR)
CBW:	RR42_s1162
BMA:	BMAA1338
BMV:	BMASAVP1_0321
BML:	BMA10229_0597
BMN:	BMA10247_A0970
BMAL:	DM55_4184
BMAE:	DM78_3315
BMAQ:	DM76_4884
BMAI:	DM57_10360
BMAF:	DM51_4991
BMAZ:	BM44_4148
BMAB:	BM45_3270
BPS:	BPSS0894
BPM:	BURPS1710b_A2492(hcaA12)
BPL:	BURPS1106A_A1232
BPD:	BURPS668_A1305
BPSE:	BDL_4182
BPSM:	BBQ_5243
BPSU:	BBN_4353
BPSD:	BBX_6022
BPZ:	BP1026B_II0981
BPQ:	BPC006_II1248
BPK:	BBK_3544
BPSH:	DR55_4442
BPSA:	BBU_5137
BPSO:	X996_4130
BUT:	X994_6231
BTE:	BTH_II1503
BTQ:	BTQ_4790
BTJ:	BTJ_3422
BTZ:	BTL_4270
BTD:	BTI_5713
BTV:	BTHA_3687
BTHE:	BTN_3421
BTHM:	BTRA_4172
BTHA:	DR62_3494
BTHL:	BG87_4246
BOK:	DM82_5067
BOC:	BG90_5528
BUR:	Bcep18194_A6009 Bcep18194_B1103
BCN:	Bcen_2070 Bcen_3656
BCH:	Bcen2424_2681 Bcen2424_4711
BCM:	Bcenmc03_2710 Bcenmc03_5589
BCJ:	BCAL0922 BCAM1854
BCEN:	DM39_2771 DM39_5956
BCEW:	DM40_4682
BCEO:	I35_2746 I35_5732
BAM:	Bamb_2734 Bamb_4105
BAC:	BamMC406_4570
BMU:	Bmul_0616 Bmul_3982
BMJ:	BMULJ_02644(hcaC)
BMK:	DM80_2238 DM80_5290
BMUL:	NP80_2816 NP80_4626
BCT:	GEM_3763
BCED:	DM42_2390 DM42_6096
BCEP:	APZ15_29460
BDL:	AK34_3780 AK34_407
BPYR:	ABD05_03435 ABD05_26385
BCON:	NL30_02790 NL30_26500
BUB:	BW23_5507
BDF:	WI26_22300 WI26_30260
BLAT:	WK25_25845
BTEI:	WS51_06805
BSEM:	WJ12_29395
BPSL:	WS57_04735
BMEC:	WJ16_13770 WJ16_28015
BSTG:	WT74_28435
BGP:	BGL_2c12470
BGE:	BC1002_3448
BGF:	BC1003_5017
BGD:	bgla_2g11260
BGO:	BM43_4773
BYI:	BYI23_C011400 BYI23_C013140 BYI23_D006380 BYI23_D006900
BUO:	BRPE64_CCDS01070 BRPE64_DCDS05220 BRPE64_DCDS05840
BUE:	BRPE67_CCDS00880 BRPE67_CCDS13360 BRPE67_DCDS08200 BRPE67_DCDS08780 BRPE67_ECDS03370
BUL:	BW21_5400
BUQ:	AC233_26365
BPLA:	bpln_1g12640 bpln_2g13310
BUD:	AQ610_26190
BXB:	DR64_5519
BPH:	Bphy_4231 Bphy_6777 Bphy_7180
BPX:	BUPH_01301
BFN:	OI25_4844 OI25_5507
BCAI:	K788_0000319 K788_0000818 K788_0002999
PSPW:	BJG93_18215
PPK:	U875_05005
PPNO:	DA70_22080
PRB:	X636_04430
PSPU:	NA29_13005
BPE:	BP0586
BPC:	BPTD_0595
BPER:	BN118_3481
BPET:	B1917_3468
BPEU:	Q425_35630
BPA:	BPP0276
BPAR:	BN117_0274
BBR:	BB0279
BBM:	BN115_0264
BBH:	BN112_3138
BBX:	BBS798_0274
BAV:	BAV1581
BBRO:	BAU06_12320
BFZ:	BAU07_14160
AXY:	AXYL_02471
AIS:	BUW96_02635
AKA:	TKWG_00640
AFA:	UZ73_04220 UZ73_14590
PHN:	PAEH1_07425
POL:	Bpro_4275
VAP:	Vapar_4288
CTT:	CtCNB1_2889
CTES:	O987_17445
ADK:	Alide2_3869
CFU:	CFU_0344(mocE)
CPRA:	CPter91_1100
LCH:	Lcho_2166 Lcho_3303
TBD:	Tbd_0271
MMB:	Mmol_1123
MEH:	M301_0845
AZA:	AZKH_1938 AZKH_2784(fdx)
AZI:	AzCIB_2743
MXA:	MXAN_2758
MFU:	LILAB_21545
MSD:	MYSTI_03193
MYM:	A176_004267
CCX:	COCOR_05289(hcaC)
SUR:	STAUR_3513
AGE:	AA314_06883
VIN:	AKJ08_1081
LLU:	AKJ09_04260
HOH:	Hoch_5508
MLO:	mll1732 mlr4999 mlr7628
MLN:	A9174_02350 A9174_17765 A9174_27885
MCI:	Mesci_0490 Mesci_3021
MOP:	Mesop_0471 Mesop_3409
MAM:	Mesau_00614 Mesau_03288
MAMO:	A6B35_05105 A6B35_14795 A6B35_23575 A6B35_26425
MESW:	A9K65_002455 A9K65_016415
AAK:	AA2016_2136
SME:	SM_b20819(mocE) SMc01993
SMK:	Sinme_2576 Sinme_5132
SMQ:	SinmeB_2356 SinmeB_4106 SinmeB_5873
SMX:	SM11_chr2681 SM11_pC1391(mocE) SM11_pD0990(mocE)
SMI:	BN406_02375 BN406_06059(mocE)
SMEG:	C770_GR4Chr2628 C770_GR4pD1029
SMEL:	SM2011_a2053 SM2011_b20819(mocE) SM2011_c01993
SMER:	DU99_14040 DU99_24435 DU99_30410
SMD:	Smed_0909 Smed_5006
RHI:	NGR_b17100 NGR_b23520(mocE)
SFH:	SFHH103_04882(mocE) SFHH103_05516(mocE)
SFD:	USDA257_c12540
SIX:	BSY16_218 BSY16_4253 BSY16_4856
SAME:	SAMCFNEI73_pC0628 SAMCFNEI73_pC1130(mocE)
EAD:	OV14_a0852
EAH:	FA04_24360 FA04_27085
ARA:	Arad_9583(mocEe)
ARO:	B0909_14380
REC:	RHECIAT_PA0000368(mocEa)
REL:	REMIM1_CH02676 REMIM1_PD00468
REI:	IE4771_CH02786 IE4771_PC00417
REP:	IE4803_CH02756 IE4803_PA00404
RLE:	pRL110621
RLT:	Rleg2_6029
RLG:	Rleg_7184
RLB:	RLEG3_05705 RLEG3_23670
RLU:	RLEG12_01510 RLEG12_23015
RTR:	RTCIAT899_PC05280 RTCIAT899_PC07060
RHL:	LPU83_2620(CAO) LPU83_3869(mocE)
RHN:	AMJ98_CH02799 AMJ98_PD00454
RPHA:	AMC79_CH02786 AMC79_PB00377
RHX:	AMK02_CH02730 AMK02_PE00461
NGL:	RG1141_PA12080
NGG:	RG540_PA06900
SHZ:	shn_13525 shn_28505
BJA:	bll7906 blr3358
RPX:	Rpdx1_0606
MET:	M446_5690
MOR:	MOC_3741
MAQU:	Maq22A_c05965(nirD)
BID:	Bind_2768
PSIN:	CAK95_00370
JAN:	Jann_1457
PYE:	A6J80_22165
LMD:	METH_07050
PTP:	RCA23_c27130
CMAR:	IMCC12053_2590
MALG:	MALG_04164
CON:	TQ29_16205
DON:	BSK21_15070
NPP:	PP1Y_AT13327
NRE:	BES08_04970
SWI:	Swit_0893 Swit_2251
SPMI:	K663_17211 K663_20493
SPHR:	BSY17_3468 BSY17_3925(carAc) BSY17_552
CIJ:	WG74_11965
SPHG:	AZE99_00970
BLAS:	BSY18_2730 BSY18_733
ELQ:	Ga0102493_111518
ERY:	CP97_03095
AMV:	ACMV_P1_01410
TMO:	TMO_b0116(bedB)
LAO:	AOX59_16845
PMS:	KNP414_04439
PMQ:	PM3016_3849
PMW:	B2K_20075
AAC:	Aaci_0991
AAD:	TC41_1004(hcaC)
BTS:	Btus_0578
STH:	STH2039
AWO:	Awo_c21300
TMR:	Tmar_2043
SAY:	TPY_3322(hcaC)
SAP:	Sulac_1589
MSM:	MSMEG_1462
MSG:	MSMEI_1426
MSB:	LJ00_07305
MSN:	LI99_07305
MSH:	LI98_07305
MSA:	Mycsm_01989 Mycsm_03751
MVA:	Mvan_1329
MAB:	MAB_4369c
MAY:	LA62_22200
MABO:	NF82_21890
MAZ:	LA61_22095
MNE:	D174_06790 D174_16950
MYV:	G155_08420
MGO:	AFA91_31590
MFT:	XA26_16850
MPHL:	MPHLCCUG_01330(todB)
MVQ:	MYVA_1137
ASD:	AS9A_0977(nirD) AS9A_1008
CDR:	CDHC03_1953(hcaC)
CHN:	A605_13885
CMD:	B841_10280
CAZ:	CARG_03215
CII:	CIMIT_11735
CHM:	B842_12625
CMQ:	B840_12305
CMV:	CMUST_15085
NFR:	ERS450000_00302(bphA3)
NBR:	O3I_018390
NNO:	NONO_c29030
RHA:	RHA1_ro04376
REB:	XU06_31875
ROP:	ROP_42810 ROP_70810
ROA:	Pd630_LPD00824 Pd630_LPD05970
REQ:	REQ_35070
RPY:	Y013_18105
RHB:	NY08_3777
RAV:	AAT18_02380 AAT18_09375
RFA:	A3L23_02132(hcaC)
RHW:	BFN03_15840
GOR:	KTR9_1262
SCO:	SCO1923(SCC22.05c)
SMA:	SAV_6327(hcaC1) SAV_6955(hcaC2)
SGR:	SGR_5597
SGB:	WQO_07360
SCB:	SCAB_2181(hcaC) SCAB_70051 SCAB_7071(nirD)
SSX:	SACTE_1346
SVL:	Strvi_5717 Strvi_7013
SCT:	SCAT_0381 SCAT_1085(hcaC)
SCY:	SCATT_03930 SCATT_10800
SFA:	Sfla_4900
SBH:	SBI_00365 SBI_02592 SBI_08050(hcaC)
SHY:	SHJG_2825 SHJG_3371
SHO:	SHJGH_2589 SHJGH_3136
SVE:	SVEN_1554
SDV:	BN159_6567 BN159_7394(nirD)
SALB:	XNR_4939
SALS:	SLNWT_1475 SLNWT_5979
STRP:	F750_1782
SFI:	SFUL_1482
SCI:	B446_09985
SRC:	M271_36720 M271_43610
SALU:	DC74_1381 DC74_1697 DC74_2398
SALL:	SAZ_07420 SAZ_09015 SAZ_13340
SLV:	SLIV_28100
SGU:	SGLAU_08590
SVT:	SVTN_09230 SVTN_36975
STRE:	GZL_06610 GZL_07817
SCW:	TU94_08170
SLD:	T261_6255 T261_7189 T261_7395
SXI:	SXIM_08740
STRM:	M444_09820
STRC:	AA958_05580 AA958_14035
SAMB:	SAM23877_1994(bedB)
SPRI:	SPRI_5611
SCZ:	ABE83_28445
SCX:	AS200_33510 AS200_38680
SRW:	TUE45_01806(hcaC_1) TUE45_02413(hcaC_2)
STRF:	ASR50_09345
SLE:	sle_52180(sle_52180)
SRN:	A4G23_01135(bnzC)
SPAV:	Spa2297_05200 Spa2297_07745
SLC:	SL103_09655 SL103_13615 SL103_14810
STRT:	A8713_07095
SCLF:	BB341_22435
SGS:	AVL59_25805 AVL59_36430
STSI:	A4E84_09760 A4E84_36425 A4E84_39290
SLS:	SLINC_2219 SLINC_8109
SNR:	SNOUR_30755 SNOUR_35715
SPLU:	LK06_006455
STRD:	NI25_29580
SNW:	BBN63_26970
KSK:	KSE_55630
TWH:	TWT_335
TWS:	TW436
LXX:	Lxx11670
LXY:	O159_12800
CMI:	CMM_1729
CMS:	CMS1973
CMC:	CMN_01709
CMH:	VO01_07880
MTS:	MTES_3645
MIM:	AKG07_05245
MIO:	AOA12_12825 AOA12_16375 AOA12_18555
MIP:	AXH82_15795
MCW:	A8L33_08950 A8L33_09525
MPAL:	BO218_04960
MIH:	BJP65_02085
MICR:	BMW26_09770
RLA:	Rhola_00007930
RPLA:	A4Z71_03820
RTX:	TI83_06710
RTC:	APU90_10375
RTN:	A6122_1257
CUM:	NI26_08460
CUB:	BJK06_18040
MVD:	AWU67_05565
FRP:	AX769_12695
AGY:	ATC03_09780
CART:	PA27867_1796 PA27867_2171
CRY:	B7495_08770 B7495_16020
CPHY:	B5808_09025
ART:	Arth_2105
ARR:	ARUE_c22620
ARM:	ART_0722
ARI:	UM93_03990
ARL:	AFL94_14245
ARE:	AL755_11465
AAQ:	AOC05_06660
ARH:	AHiyo8_21690
ARY:	ATC04_03695
ARW:	MB46_05145
ARZ:	AUT26_10415
AAU:	AAur_2106
ACH:	Achl_1847
APN:	Asphe3_18240
PSUL:	AU252_21915
AAI:	AARI_27910(hcaC)
GAR:	AOZ07_14300
RSA:	RSal33209_2237
KFV:	AS188_03575
MLU:	Mlut_20070
SATK:	SA2016_3461
NAE:	BHE16_09190
BCV:	Bcav_2338
BFA:	Bfae_14640
BRX:	BH708_01785
DVA:	DAD186_11840
JDE:	Jden_1142
KSE:	Ksed_13360
DNI:	HX89_07700
LMOI:	VV02_14650
XCE:	Xcel_1359
IVA:	Isova_1370
IDO:	I598_0893(todB)
CET:	B8281_14085
CCEU:	CBR64_17335
SKE:	Sked_21930
CFL:	Cfla_1673
CFI:	Celf_1695
CGA:	Celgi_1921
ICA:	Intca_2070
ARS:	ADJ73_13070
SERJ:	SGUI_0265
JTE:	ASJ30_08220
BLY:	A2T55_09585
BLIN:	BLSMQ_1931 BLSMQ_2137
PAC:	PPA1547
PAK:	HMPREF0675_4614
PAV:	TIA2EST22_07755
PAX:	TIA2EST36_07740
PAZ:	TIA2EST2_07670
PAW:	PAZ_c16350
PAD:	TIIST44_00735
PCN:	TIB1ST10_07950
PACC:	PAC1_08130
PACH:	PAGK_0633
PACN:	TIA1EST1_07750
CACN:	RN83_08200
PRA:	PALO_03240
PFR:	PFREUD_14960
PFRE:	RM25_1416
PRL:	BCB70_10655
PPC:	HMPREF9154_1082(ndoA)
PBO:	PACID_22490
AACI:	ASQ49_10640
MPH:	MLP_14510
TFL:	RPIT_04350
TFA:	BW733_01745
TES:	BW730_07395
TEZ:	BKM78_13285
NCA:	Noca_2552
NDK:	I601_3414(andAb)
KFL:	Kfla_3280
PSIM:	KR76_13935
AER:	AERYTH_09315
TFU:	Tfu_1985
NDA:	Ndas_2961
NAL:	B005_5504
TCU:	Tcur_2226
SRO:	Sros_5985
NOA:	BKM31_05635
FRA:	Francci3_1662
FRE:	Franean1_2087
FRI:	FraEuI1c_4098 FraEuI1c_4852 FraEuI1c_5288
FAL:	FRAAL4561
FSY:	FsymDg_1716
GOB:	Gobs_2066
BSD:	BLASA_3219(sufE)
MMAR:	MODMU_2893(hcaC) MODMU_3610(sufE)
KRA:	Krad_4109
SEN:	SACE_3146(hcaC2) SACE_4486(hcaC2)
SVI:	Svir_18750
AMD:	AMED_7562(hcaC) AMED_7994(hcaC)
AMN:	RAM_38855 RAM_41075
AMM:	AMES_7450(hcaC) AMES_7875(hcaC)
AMZ:	B737_7450(hcaC) B737_7875(hcaC)
AOI:	AORI_6807(hcaC)
AJA:	AJAP_05080
AMQ:	AMETH_4494(hcaC2)
ALU:	BB31_02500
PDX:	Psed_4208
PSEA:	WY02_08060 WY02_22335
PSEE:	FRP1_20325
PSEH:	XF36_06485
PSEQ:	AD006_27740 AD006_28750
PECQ:	AD017_07335 AD017_29140
PHH:	AFB00_18100 AFB00_24060
AMI:	Amir_5152
SESP:	BN6_62310
KAL:	KALB_3166 KALB_3720
KPHY:	AOZ06_00355 AOZ06_36175
LED:	BBK82_00775 BBK82_27685
AHM:	TL08_06770 TL08_11815
ACTI:	UA75_06585 UA75_12610
ACAD:	UA74_06585 UA74_12530
ALL:	CRK56354
STP:	Strop_2209 Strop_3081
SAQ:	Sare_1258 Sare_3308
MAU:	Micau_4316
MIL:	ML5_3987
VMA:	VAB18032_25930
AMS:	AMIS_16280
ASE:	ACPL_1873(bedB)
ACTN:	L083_2177
AFS:	AFR_10675
CAI:	Caci_2265 Caci_4332
SNA:	Snas_2444
AHE:	Arch_0935
MCU:	HMPREF0573_11880
TPY:	CQ11_00090
TPYO:	X956_05225
ASG:	FB03_01765
AVU:	BK816_05460
TBI:	Tbis_1970
RRD:	RradSPS_2725
CWO:	Cwoe_5395
AFO:	Afer_0562
AYM:	YM304_13590
ABAI:	IMCC26256_111967
GLP:	Glo7428_2182
RRS:	RoseRS_0716
RCA:	Rcas_0311 Rcas_2708
CAU:	Caur_0704 Caur_3486
CAG:	Cagg_0955 Cagg_2821
CHL:	Chy400_0760 Chy400_3755
HAU:	Haur_0406
TRO:	trd_A0838
STI:	Sthe_3233
ATM:	ANT_17920
CAP:	CLDAP_20390
DRA:	DR_1950
DGE:	Dgeo_0455
DDR:	Deide_16700
DMR:	Deima_2259
DPT:	Deipr_0604
DGO:	DGo_CA2273
DPD:	Deipe_3779
DSW:	QR90_00970
DCH:	SY84_13115
DAB:	AUC44_04030
DPU:	SU48_11975
TRA:	Trad_0260
TTH:	TT_C1490
TTJ:	TTHA1841
TTS:	Ththe16_1858
TTL:	TtJL18_1939
TSC:	TSC_c03890
THC:	TCCBUS3UF1_19430
TOS:	Theos_0110
TAQ:	TO73_0290
TPAR:	AV541_01515
TBC:	A0O31_01269
MRB:	Mrub_0780
MRE:	K649_03535
MSV:	Mesil_1004
MHD:	Marky_1898
TTR:	Tter_1694
MIN:	Minf_2462(nirD)
PSL:	Psta_2904
PIR:	VN12_27040(ndoA)
PBS:	Plabr_0912
PLS:	VT03_26350(carAc) VT03_29855(hcaC)
PLH:	VT85_08740(nagAb)
FMR:	Fuma_05750(hcaC)
IPA:	Isop_3231
SACI:	Sinac_2619 Sinac_5289
PBOR:	BSF38_04069(carAc)
STA:	STHERM_c05740
STQ:	Spith_0593
SFC:	Spiaf_1698
SLR:	L21SP2_0864
LIL:	LA_3561(nirD)
LIE:	LIF_A2866(nirD)
LIC:	LIC_10633(bedB)
LIS:	LIL_10643(nirD)
LBJ:	LBJ_2444(nirD)
LBL:	LBL_0668(nirD)
LBI:	LEPBI_I1918
LBF:	LBF_1863(nirD)
LST:	LSS_15531
LAJ:	A0128_15505
GAU:	GAU_3031
GPH:	GEMMAAP_15370
GBA:	J421_2086
CPI:	Cpin_0589
SPHN:	BV902_14045
BBD:	Belba_0859
BBAU:	AEM51_13280
IAL:	IALB_2268(hcaC)
NDE:	NIDE2767
MEV:	Metev_2200
MPY:	Mpsy_1353
MPD:	MCP_0385
FAC:	FACI_IFERC01G0989
FAI:	FAD_0012
SOL:	Ssol_2796
SSOA:	SULA_2818
SSOL:	SULB_2819
SSOF:	SULC_2816
SIN:	YN1551_2359
SII:	LD85_0660
AMAN:	B6F84_04115
PYR:	P186_1883
POG:	Pogu_1789
PYW:	PYWP30_02118
NMR:	Nmar_0308
NIR:	NSED_01485 NSED_02490 NSED_05555
NID:	NPIRD3C_0710(bedB)
NIN:	NADRNF5_0989 NADRNF5_1692 NADRNF5_1944
NKR:	NKOR_01390 NKOR_02550 NKOR_05465
NCT:	NMSP_0657(sdx_1) NMSP_1400(sdx_3)
NGA:	Ngar_c10860 Ngar_c24320
NVN:	NVIE_012450 NVIE_025420 NVIE_030140
NEV:	NTE_01296 NTE_02651 NTE_03028
TAA:	NMY3_01267(nagAb_2) NMY3_01309(nagAb_3)
CSU:	CSUB_C1378 CSUB_C1380
NBV:	T478_0233 T478_0447
TAH:	SU86_001235 SU86_004420
NDV:	NDEV_0450

» show all

Reference

PMID:9603882

Authors

Diaz E, Ferrandez A, Garcia JL.

Title

Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.

Journal

J Bacteriol 180:2915-23 (1998)

Reference

PMID:17142386

Authors

Vezina J, Barriault D, Sylvestre M

Title

Family shuffling of soil DNA to change the regiospecificity of Burkholderia xenovorans LB400 biphenyl dioxygenase.

Journal

J Bacteriol 189:779-88 (2007)
DOI:10.1128/JB.01267-06

LinkDB

ORTHOLOGY: K00529

Entry

K00529 KO

Name

hcaD

Definition

3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]

Pathway

ko00071	Fatty acid degradation
ko00360	Phenylalanine metabolism
ko01220	Degradation of aromatic compounds

Module

M00545

Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Overview
   01220 Degradation of aromatic compounds
    K00529  hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component
  Lipid metabolism
   00071 Fatty acid degradation
    K00529  hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component
  Amino acid metabolism
   00360 Phenylalanine metabolism
    K00529  hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component
KEGG modules [BR:ko00002]
Pathway module
  Nucleotide and amino acid metabolism
   Aromatic amino acid metabolism
    M00545  Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
     K00529  hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.18  Acting on iron-sulfur proteins as donors
   1.18.1  With NAD+ or NADP+ as acceptor
    1.18.1.3  ferredoxin---NAD+ reductase
     K00529  hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component

Other DBs

RN:

R02000 R06782 R06783

COG:

COG0446

GO:

0008860

Genes

ECO:	b2542(hcaD)
ECJ:	JW2526(hcaD)
ECD:	ECDH10B_2709(hcaD)
EBW:	BWG_2306(hcaD)
ECOK:	ECMDS42_2086(hcaD)
ECE:	Z3814(hcaD)
ECS:	ECs3408
ECF:	ECH74115_3774(hcaD)
ETW:	ECSP_3486(hcaD)
ELX:	CDCO157_3175
EOJ:	ECO26_3589(hcaD)
EOI:	ECO111_3266(hcaD)
EOH:	ECO103_3062(hcaD)
EOK:	G2583_3072(hcaD)
ELR:	ECO55CA74_15205
ECX:	EcHS_A2694(hcaD)
ECW:	EcE24377A_2827(hcaD)
ECM:	EcSMS35_2695(hcaD)
ECY:	ECSE_2829
ECK:	EC55989_2828(hcaD)
ECT:	ECIAI39_2743(hcaD)
EOC:	CE10_2974(hcaD)
EUM:	ECUMN_2862(hcaD)
ELO:	EC042_2746(hcaD)
ELH:	ETEC_2699
ESO:	O3O_18945
ESM:	O3M_06750
ESL:	O3K_06705
ECL:	EcolC_1135
EBR:	ECB_02434(hcaD)
EBD:	ECBD_1142
EKO:	EKO11_1191
EKF:	KO11_10110(hcaD)
EDH:	EcDH1_1126
EDJ:	ECDH1ME8569_2469(hcaD)
EUN:	UMNK88_3195
ELW:	ECW_m2768(hcaD)
ELL:	WFL_13555(hcaD)
ELP:	P12B_c2642(hcaD)
EBL:	ECD_02434(hcaD)
EBE:	B21_02398(hcaD)
ECOA:	APECO78_16440
ECOL:	LY180_13040
SFV:	SFV_2590(hcaD)
SFE:	SFxv_2845(hcaD)
SFN:	SFy_3676
SFS:	SFyv_3753
SFT:	NCTC1_02845(hcaD_1) NCTC1_02846(hcaD_2)
SSN:	SSON_2624(hcaD)
SHQ:	A0259_16435
ENC:	ECL_04260
ENO:	ECENHK_18450
ECLO:	ENC_31820
EEC:	EcWSU1_03730(thcD)
ENL:	A3UG_18800
ECLG:	EC036_36560
ECLE:	ECNIH2_18990
ECLN:	ECNIH4_04275
ECLI:	ECNIH5_17900
ECLX:	LI66_18670
ECLY:	LI62_20130
ECLZ:	LI64_17560
ECLA:	ECNIH3_17980
ECLC:	ECR091_17915
EHM:	AB284_07120
EKB:	BFV64_19180
ELG:	BH714_21115
EXF:	BFV63_18330
KPN:	KPN_03366
KPM:	KPHS_44330
KPH:	KPNIH24_06715
KPV:	KPNIH29_19740 KPNIH29_22320
KPW:	KPNIH30_22325
KPY:	KPNIH31_21580
KPG:	KPNIH32_23180
KPC:	KPNIH10_22080
KPQ:	KPR0928_21590
KPT:	VK055_4115
KPR:	KPR_4631
KPJ:	N559_0870
KPI:	D364_17330
KPA:	KPNJ1_00868
KPS:	KPNJ2_00902
KPB:	FH42_12805
KPNE:	KU54_004255
KPNU:	LI86_04260
KOC:	AB185_11460
KQU:	AVR78_00710
EAE:	EAE_03025
EAR:	CCG33376
CFD:	CFNIH1_24145
CIF:	AL515_17230
EBT:	EBL_c05880
ROR:	RORB6_22680
RON:	TE10_23735
CNT:	JT31_15875
LAZ:	A8A57_17405
EBF:	D782_0770 D782_1127
YSI:	BF17_03535
YRO:	CH64_1873
SPE:	Spro_3963
SRR:	SerAS9_4169
SRL:	SOD_c39190(thcD)
SRY:	M621_21050
SPLY:	Q5A_021000(thcD)
SRS:	SerAS12_4170
SRA:	SerAS13_4170
SMAF:	D781_3684
SMW:	SMWW4_v1c40720(hcaD)
SMAR:	SM39_3555
SMAC:	SMDB11_3370
SLQ:	M495_20695
SERF:	L085_08140
SERS:	SERRSCBI_19800
SFW:	WN53_02595 WN53_15160
SFG:	AV650_10700 AV650_25320
SRZ:	AXX16_1401
SFO:	Z042_06965
PANP:	PSNIH2_01770
PLU:	plu2209
PAY:	PAU_02352(hcaD)
PTT:	VY86_20015
PSI:	S70_19015
PSX:	DR96_2720
PSTA:	BGK56_01105
PRG:	RB151_039990(andAa)
PFQ:	QQ39_00775
XCV:	XCV2179
XAX:	XACM_2265
XPE:	BJD13_05020
PSD:	DSC_14560
SNJ:	A7E77_00450
FAU:	Fraau_2257
VNA:	PN96_06460
VEJ:	VEJY3_06590
VFU:	vfu_A01969
VNI:	VIBNI_B2032
PRE:	PCA10_27680
PALC:	A0T30_16855
PCQ:	PcP3B5_42510(thcD_2)
PPJ:	RK21_01231
PSP:	PSPPH_2341
PCI:	PCH70_21490
PFS:	PFLU_2392
PFE:	PSF113_3383(ethA)
PFC:	PflA506_2267
PFW:	PF1751_v1c20830
PFB:	VO64_5562
PFF:	PFLUOLIPICF726295
PPZ:	H045_07315
PTV:	AA957_02865
PAZO:	AYR47_18700
PSK:	U771_12630
PFZ:	AV641_10000
PPSY:	AOC04_06870
PUR:	AOC03_11575
ACB:	A1S_0951
ABY:	ABAYE2843
ABC:	ACICU_00912
ABN:	AB57_1026
ABB:	ABBFA_002661
ABX:	ABK1_0936
ABZ:	ABZJ_01052
ABR:	ABTJ_02860
ABD:	ABTW07_1041
ABH:	M3Q_1249
ABAD:	ABD1_09030
ABJ:	BJAB07104_01046
ABAB:	BJAB0715_01064
ABAJ:	BJAB0868_01060
ABAZ:	P795_12955
ABK:	LX00_04780
ABAU:	IX87_00780
ABAA:	IX88_06760
ABW:	BL01_11460
ABAL:	ABLAC_17170
ACC:	BDGL_000228(thcD)
ANO:	RR32_13380
ACD:	AOLE_14590
ACI:	ACIAD0991 ACIAD1580
ATT:	AMQ28_08990
AEI:	AOY20_01925
ACW:	A0J50_12695 A0J50_18470
ACV:	AMD27_03965
AHL:	AHTJS_05485 AHTJS_05730
ASOL:	BEN76_08675 BEN76_16500
ALA:	BFG52_11200
ASJ:	AsACE_CH00363(hcaD)
PPHE:	PP2015_459
PBW:	D172_009455
PTN:	PTRA_a0478(hcaD)
PLZ:	S4054249_08545 S4054249_08550
MAQ:	Maqu_0601
MHC:	MARHY2840(ahpH)
MAD:	HP15_27
MSR:	AU15_21460
MLQ:	ASQ50_08920
ASP:	AOR13_2913
ASQ:	AVL57_04235
AAW:	AVL56_03010
GAG:	Glaag_0387 Glaag_2451
GPS:	C427_3050
SPOI:	IMCC21906_01684
ZAL:	AZF00_04650 AZF00_17890
WOC:	BA177_07100
CSA:	Csal_0136
HHU:	AR456_06915
ABO:	ABO_0203
ADI:	B5T_02077
APAC:	S7S_11265
ALN:	AS19_02100
AXE:	P40_09940
MME:	Marme_4085
MARS:	A8C75_03260 A8C75_19370
OME:	OLMES_4338
PSPI:	PS2015_1900
GPB:	HDN1F_17570 HDN1F_19700
AQL:	BXU06_16210
RSC:	RCFBP_20194
RSL:	RPSI07_2133(hcaD)
RSN:	RSPO_c02130(nirB)
RPJ:	N234_12820 N234_24835
REU:	Reut_A1474 Reut_B3777 Reut_B4722 Reut_C6322
REH:	H16_A1630(h16_A1630) H16_B0802(h16_B0802)
CNC:	CNE_1c16380 CNE_1c17570(bedA) CNE_2c07500(hcaD) CNE_BB1p12720(thcD)
CBW:	RR42_s1161
BMA:	BMAA1326
BMV:	BMASAVP1_0309
BML:	BMA10229_0585
BMN:	BMA10247_A0982
BMAL:	DM55_4196
BMAE:	DM78_3327
BMAQ:	DM76_4896
BMAI:	DM57_10420
BMAF:	DM51_4979
BMAZ:	BM44_4160
BMAB:	BM45_3282
BPS:	BPSS0906
BPM:	BURPS1710b_A2504(mopA)
BPL:	BURPS1106A_A1244
BPD:	BURPS668_A1317
BPSE:	BDL_4194
BPSM:	BBQ_5231
BPSU:	BBN_4365
BPSD:	BBX_6034
BPZ:	BP1026B_II0993
BPQ:	BPC006_II1260
BPK:	BBK_3532
BPSH:	DR55_4430
BPSA:	BBU_5125
BPSO:	X996_4142
BUT:	X994_5937 X994_6219
BTE:	BTH_II1491
BTQ:	BTQ_4778
BTJ:	BTJ_3410
BTZ:	BTL_4258
BTD:	BTI_5725
BTV:	BTHA_3699
BTHE:	BTN_3433
BTHM:	BTRA_4184
BTHA:	DR62_3506
BTHL:	BG87_4234
BOK:	DM82_5079
BOC:	BG90_5516
BUR:	Bcep18194_A6008 Bcep18194_B1115 Bcep18194_B2965
BCN:	Bcen_2069 Bcen_3668
BCH:	Bcen2424_2680 Bcen2424_4699
BCM:	Bcenmc03_2709 Bcenmc03_5601 Bcenmc03_6887
BCJ:	BCAL0923 BCAM1842
BCEN:	DM39_2770 DM39_4068 DM39_5968
BCEW:	DM40_4670
BCEO:	I35_2745 I35_5720
BAM:	Bamb_2733 Bamb_4093
BAC:	BamMC406_4558
BMU:	Bmul_0617 Bmul_3994
BMJ:	BMULJ_02643(hcaD)
BMK:	DM80_1417 DM80_2239(thcD) DM80_5302
BMUL:	NP80_2815 NP80_4614
BCT:	GEM_0757 GEM_3775
BCED:	DM42_2391 DM42_6108
BCEP:	APZ15_29520
BDL:	AK34_3792 AK34_408
BPYR:	ABD05_03430 ABD05_26445
BCON:	NL30_02850 NL30_26495
BUB:	BW23_5495
BDF:	WI26_22240 WI26_30270
BLAT:	WK25_25785
BTEI:	WS51_06745
BSEM:	WJ12_29335
BPSL:	WS57_04795
BMEC:	WJ16_13765 WJ16_27955
BSTG:	WT74_28375
BGL:	bglu_2g18570
BGP:	BGL_2c12490 BGL_2c24800
BGU:	KS03_4077
BUG:	BC1001_4036 BC1001_4724
BGF:	BC1003_5029
BGD:	bgla_2g11380 bgla_2g24380
BGO:	BM43_4148 BM43_4785 BM43_6131
BYI:	BYI23_C011280 BYI23_D003200 BYI23_D006370 BYI23_D012580 BYI23_D012650
BUO:	BRPE64_CCDS00950 BRPE64_DCDS05850(hcaD) BRPE64_ECDS02340
BUE:	BRPE67_CCDS00760 BRPE67_DCDS01240 BRPE67_DCDS01310 BRPE67_DCDS05000 BRPE67_DCDS08190
BUL:	BW21_5412
BUQ:	AC233_26425
BPLA:	bpln_1g12650 bpln_2g13330 bpln_2g25110
BUD:	AQ610_26130
BXE:	Bxe_A3591 Bxe_B0185 Bxe_C0579 Bxe_C0951
BXB:	DR64_1288 DR64_5531 DR64_7499 DR64_7668 DR64_7867(thcD)
BPH:	Bphy_3909 Bphy_4243 Bphy_6775 Bphy_6979
BPX:	BUPH_00619 BUPH_01289
BPY:	Bphyt_7069
BFN:	OI25_3033(thcD) OI25_3902(thcD) OI25_5519
BCAI:	K788_0000320 K788_0000480 K788_0000830 K788_0005442
PSPW:	BJG93_04740 BJG93_29290 BJG93_33780
PPK:	U875_10885
PPNO:	DA70_03300
PPNM:	LV28_03030
PRB:	X636_23810
PPUL:	RO07_21920
PSPU:	NA29_13010 NA29_14990
PAPI:	SG18_20970
PVE:	UC34_07190 UC34_13320
POX:	MB84_17910
PFG:	AB870_00390
PNR:	AT302_13295 AT302_18755
BPE:	BP0585
BPC:	BPTD_0594 BPTD_1633
BPER:	BN118_1479 BN118_1590 BN118_3482
BPET:	B1917_1559 B1917_3469
BPEU:	Q425_35640
BPA:	BPP0275 BPP2184 BPP2834
BPAR:	BN117_0685 BN117_1343
BBR:	BB0278 BB0727 BB1107 BB1581 BB3155
BBM:	BN115_0263 BN115_1053 BN115_1535 BN115_1996
BBH:	BN112_0957 BN112_1875 BN112_2343 BN112_3139
BBX:	BBS798_0273 BBS798_1075 BBS798_1540 BBS798_2987
BAV:	BAV0660 BAV1582
BHO:	D560_1526 D560_1678(thcD)
BHM:	D558_1517 D558_1666(thcD)
BHZ:	ACR54_01067(camA) ACR54_01699(andAa) ACR54_04420(thcD)
BTRM:	SAMEA390648702391(camA)
BBRO:	BAU06_12315
BFZ:	BAU07_14165 BAU07_22110
AXY:	AXYL_01296 AXYL_02470(hcaD) AXYL_03915
AXN:	AX27061_2913
AXS:	LH59_13695
AXX:	ERS451415_02891(thcD_2)
ADT:	APT56_13975
AIS:	BUW96_02630 BUW96_09060 BUW96_19785
PUT:	PT7_2669
AKA:	TKWG_00635
AMIM:	MIM_c31590
CDN:	BN940_14201
AFA:	UZ73_04230 UZ73_14585
PHN:	PAEH1_07615
RFR:	Rfer_0300
RHY:	RD110_24895
POL:	Bpro_5151 Bpro_5300
AJS:	Ajs_0213
ACK:	C380_15960(bphA4)
ACID:	CBP33_05445
VEI:	Veis_2790 Veis_4603
DAC:	Daci_2353
DEL:	DelCs14_4306
DTS:	BI380_12455
DHK:	BO996_10970
VAP:	Vapar_4035 Vapar_4289 Vapar_5346
VPE:	Varpa_4697
VPD:	VAPA_1c07010 VAPA_1c20380 VAPA_1c41830
VAA:	AX767_04700
CTES:	O987_08220 O987_21880 O987_22365
CSER:	CCO03_02725
HYR:	BSY239_2683(thcD)
HYB:	Q5W_00850 Q5W_20035 Q5W_24900
HYL:	LPB072_21895
CBAA:	SRAA_1072
CBAB:	SMCB_0826
MPT:	Mpe_B0597
CFU:	CFU_0345(mocF)
CPRA:	CPter91_1101
LCH:	Lcho_3288
RGU:	A4W93_01655
AZO:	azo2529(camA)
AZI:	AzCIB_2440
AGE:	AA314_02447
CCRO:	CMC5_019520
SAMY:	DB32_000099
LLU:	AKJ09_01616
MLO:	mll5522 mlr5000
MLN:	A9174_00210 A9174_02345
MCI:	Mesci_0043 Mesci_0489
MOP:	Mesop_0043 Mesop_0470
MAM:	Mesau_00043 Mesau_00615
MAMO:	A6B35_05100 A6B35_07480 A6B35_25065 A6B35_29565 A6B35_29715 A6B35_29725 A6B35_31420
MESO:	BSQ44_20995
MESW:	A9K65_000215 A9K65_002450
AAK:	AA2016_0502 AA2016_1169 AA2016_1196 AA2016_2135 AA2016_5380
PLA:	Plav_0127
SME:	SM_b20820(mocF) SMc00914 SMc01990
SMK:	Sinme_0500 Sinme_2573 Sinme_5131
SMQ:	SinmeB_0404 SinmeB_2353 SinmeB_4105 SinmeB_5874
SMX:	SM11_chr0445 SM11_chr2678 SM11_pC1393(mocF) SM11_pD0989(mocF)
SMI:	BN406_00447 BN406_02372 BN406_06058(andAa)
SMEG:	C770_GR4Chr0788 C770_GR4Chr2625 C770_GR4pD1028
SMEL:	SM2011_b20820(mocF) SM2011_c00914 SM2011_c01990
SMER:	DU99_04080 DU99_14025 DU99_24445 DU99_30405
SMD:	Smed_0407 Smed_0908 Smed_5005
RHI:	NGR_b07640 NGR_b14750 NGR_b16350 NGR_b17090 NGR_b23540(mocF) NGR_c04050
SFH:	SFHH103_00473 SFHH103_04880(mocF) SFHH103_05517(mocF) SFHH103_06382
SFD:	USDA257_c05050(thcD1) USDA257_c12530 USDA257_c26480(thcD2)
SIX:	BSY16_219 BSY16_2202 BSY16_4248 BSY16_4858
SAME:	SAMCFNEI73_Ch0827(thcD) SAMCFNEI73_pC0630 SAMCFNEI73_pC1129 SAMCFNEI73_pC1879(thcD)
EAD:	OV14_1720 OV14_a0851
EAH:	FA04_02090 FA04_24355 FA04_27075
ATU:	Atu1013
ARA:	Arad_1563 Arad_9582(mocFe)
ATF:	Ach5_09360
ATA:	AWN88_24675
AVI:	Avi_1426 Avi_7682
AGR:	AGROH133_05000
AGC:	BSY240_1319
ARO:	B0909_08310 B0909_14390
RET:	RHE_CH01347 RHE_CH02643(mocFch) RHE_PE00444(mocFe)
REC:	RHECIAT_CH0001444 RHECIAT_CH0002771(mocFch) RHECIAT_PA0000367(mocFa)
REL:	REMIM1_CH01356 REMIM1_CH02678 REMIM1_PD00467
REI:	IE4771_CH01435 IE4771_CH02788 IE4771_PC00416 IE4771_PD00149
REP:	IE4803_CH01388 IE4803_CH02758 IE4803_PA00403 IE4803_PC00149
RLE:	RL1498 pRL110620
RLT:	Rleg2_0985 Rleg2_2299 Rleg2_6030
RLG:	Rleg_1138 Rleg_7185
RLB:	RLEG3_05700 RLEG3_16060 RLEG3_23680
RLU:	RLEG12_01515 RLEG12_16290 RLEG12_23020
RTR:	RTCIAT899_CH05730 RTCIAT899_PC05275 RTCIAT899_PC07065
RIR:	BN877_I1000(thcD)
RHL:	LPU83_1320 LPU83_2621(mocF1) LPU83_3868(mocF3)
RGA:	RGR602_CH01271 RGR602_PC02300
RHN:	AMJ98_CH01387 AMJ98_CH02801 AMJ98_PD00453
RPHA:	AMC79_CH01401 AMC79_CH02788 AMC79_PB00376
RHT:	NT26_0971(thcD)
RHX:	AMK02_CH01392 AMK02_CH02732 AMK02_PE00460
NGL:	RG1141_CH09290 RG1141_PA12070(mocF) RG1141_PB00320
NGG:	RG540_CH09480 RG540_PA03920 RG540_PA06910(mocF)
SHZ:	shn_03610 shn_13520 shn_17110 shn_28495
BME:	BMEII0557
BMEL:	DK63_2689(thcD)
BMZ:	BM28_B0697
BMG:	BM590_B0695
BMW:	BMNI_II0678
BMEE:	DK62_2713(thcD)
BMF:	BAB2_0511
BMB:	BruAb2_0502
BMC:	BAbS19_II04810
BAA:	BAA13334_II01030
BABO:	DK55_2491(thcD)
BABR:	DO74_2906(thcD)
BABT:	DK49_2748(thcD)
BABB:	DK48_2200(thcD)
BABU:	DK53_2494(thcD)
BABS:	DK51_3078(thcD)
BABC:	DO78_2564(thcD)
BMS:	BRA0729
BSI:	BS1330_II0722
BSF:	BSS2_II0692
BSUI:	BSSP1_II0670
BSUP:	BSPT1_II0668
BSUV:	BSPT2_II0670
BSUC:	BSSP2_II0681
BMT:	BSUIS_B0721
BSZ:	DK67_2693(thcD)
BSV:	BSVBI22_B0721
BSW:	IY71_14665
BOV:	BOV_A0683
BCS:	BCAN_B0736(thcD)
BSK:	BCA52141_II0179
BOL:	BCOUA_II0729
BCAR:	DK60_2428(thcD)
BCAS:	DA85_13955
BMR:	BMI_II722
BPP:	BPI_II782
BPV:	DK65_2909(thcD)
BCET:	V910_200540
BCEE:	V568_200615
BVL:	BF3285c2_0263
OAN:	Oant_3868
OAH:	DR92_4393(thcD)
OPS:	A8A54_14810
BJA:	blr2831 blr7998
BJU:	BJ6T_20740 BJ6T_69310
BJP:	RN69_10160 RN69_33630
BRA:	BRADO2481 BRADO2491 BRADO3963
BBT:	BBta_2827 BBta_2836 BBta_4333 BBta_7472
BRS:	S23_51680
AOL:	S58_51210 S58_51330
BRC:	BCCGELA001_12705 BCCGELA001_29670
BRAD:	BF49_1851
BIC:	LMTR13_29020
RPA:	RPA3782
RPB:	RPB_3656
RPC:	RPC_1647
RPD:	RPD_1802
RPE:	RPE_1676
RPT:	Rpal_4303
RPX:	Rpdx1_1562
NWI:	Nwi_2287
NHA:	Nham_2703
BOS:	BSY19_593
XAU:	Xaut_2616
SNO:	Snov_0477
MEX:	Mext_0977
MEA:	Mex_1p0755
MDI:	METDI1124
MCH:	Mchl_0941
MRD:	Mrad2831_3561
MET:	M446_2274
MPO:	Mpop_0917
MNO:	Mnod_0328
MOR:	MOC_4083
META:	Y590_03895
MAQU:	Maq22A_c07385(hcaD)
BID:	Bind_2488 Bind_2850
MSL:	Msil_0457 Msil_1470
HMC:	HYPMC_2235
FIL:	BN1229_v1_2293(fdr)
FIY:	BN1229_v1_2293(fdr)
BVR:	BVIR_2618
RHZ:	RHPLAN_01430 RHPLAN_32240
MEY:	TM49_01060
MAAD:	AZF01_13530 AZF01_18330 AZF01_20395
MMED:	Mame_03831(thcD)
PSIN:	CAK95_00945
RBM:	TEF_10365
CCR:	CC_3525
CCS:	CCNA_03640
CAK:	Caul_1879 Caul_4836 Caul_5438
CSE:	Cseg_0159 Cseg_3012
CHQ:	AQ619_00625
PZU:	PHZ_c0214
BSB:	Bresu_1559
BRD:	JL11_00620
BNE:	DA69_10290
BRG:	A4249_10685
BRL:	BZG35_10450
AEX:	Astex_1521
CBOT:	ATE48_12345
SIL:	SPO3737
SIT:	TM1040_2471
RMB:	K529_011820
RSP:	RSP_0900
RSH:	Rsph17029_2559
RSQ:	Rsph17025_3006
RSK:	RSKD131_2272
RCP:	RCAP_rcc03412(thcD)
RHP:	LPB142_14215
JAN:	Jann_0440
RDE:	RD1_0947
RLI:	RLO149_c001600
PDE:	Pden_2324 Pden_3463
PAMI:	JCM7686_0501
PYE:	A6J80_11910 A6J80_22155
PCON:	B0A89_04345
DSH:	Dshi_0114
KVU:	EIO_0493
KVL:	KVU_0054
KRO:	BVG79_00317(hcaD)
PSF:	PSE_0031
PGA:	PGA1_c29270(thcD)
PGL:	PGA2_c27200(thcD)
PGD:	Gal_00503
PHP:	PhaeoP97_00578(thcD)
OAT:	OAN307_c05190
OAR:	OA238_c01430 OA238_c44960
OTM:	OSB_01410(fdr)
LMD:	METH_15100
RED:	roselon_01418
PTP:	RCA23_c03430(thcD)
CID:	P73_0354 P73_0554 P73_1054 P73_4758
CMAR:	IMCC12053_1592 IMCC12053_2589
MALG:	MALG_03090
CON:	TQ29_01480 TQ29_05655 TQ29_19095
RSU:	NHU_03901
RHM:	B5V46_01105
RHC:	RGUI_2695
PPHR:	APZ00_08250 APZ00_12865 APZ00_24840
HAT:	RC74_04535
LAP:	ACP90_03360
LAGG:	B0E33_14835
DAA:	AKL17_1373 AKL17_3576 AKL17_3577
YAN:	AYJ57_09100
SUAM:	BOO69_01085
DON:	BSK21_00650 BSK21_12750 BSK21_15005
TPRO:	Ga0080559_TMP2340
TOM:	BWR18_14865
PABY:	Ga0080574_TMP2723
THW:	BMG03_00540 BMG03_04535
RMM:	ROSMUCSMR3_02975(thcD)
LVS:	LOKVESSMR4R_00422(camA) LOKVESSMR4R_02938(fdr)
MMR:	Mmar10_1520
HNE:	HNE_1888
HBA:	Hbal_2541 Hbal_2822
HBC:	AEM38_00295
NAR:	Saro_0216 Saro_3838
NPP:	PP1Y_AT15827 PP1Y_AT1991 PP1Y_AT31267 PP1Y_AT31272
NPN:	JI59_10655 JI59_24680
NRE:	BES08_12760 BES08_14190 BES08_19570 BES08_21215 BES08_30695
SAL:	Sala_1971
SPHK:	SKP52_00905(fdr1) SKP52_15405(fdr2) SKP52_24505
SPHP:	LH20_06665 LH20_08040 LH20_09345
SMAG:	AN936_04200
SMAZ:	LH19_16785
STER:	AOA14_02190
SGI:	SGRAN_1201(camA) SGRAN_1587(fdr) SGRAN_2775(camA2) SGRAN_3240(camA3)
SPHL:	LPB140_05875
SPHQ:	BWQ93_10240
SWI:	Swit_0898 Swit_2055
SPHM:	G432_00945
STAX:	MC45_14140
SPHI:	TS85_00730 TS85_13365
SSAN:	NX02_11185
SMY:	BJP26_09355
SPAN:	AWL63_12555 AWL63_16130
SKR:	BRX40_00660 BRX40_06640
SPLM:	BXU08_14950
SJP:	SJA_C1-25250(andAa) SJA_C1-26560
SCH:	Sphch_0328 Sphch_3944
SSY:	SLG_18830 SLG_21200
SYB:	TZ53_00150 TZ53_08020
SBD:	ATN00_11865
SPMI:	K663_06390
SPHB:	EP837_00486(hcaD)
SPHR:	BSY17_2757 BSY17_4174 BSY17_99
SINB:	SIDU_01545
CIJ:	WG74_00850 WG74_05775 WG74_06140 WG74_12060
SPHG:	AZE99_06745
BLAS:	BSY18_317
ELI:	ELI_12420
ELQ:	Ga0102493_11823
ERY:	CP97_01570 CP97_14255
EGN:	BMF35_a0541
AAY:	WYH_02138(fdr)
AMX:	AM2010_2358
AEP:	AMC99_02420
ANH:	A6F65_00548(fdr)
ADO:	A6F68_00373(fdr)
CNA:	AB433_01645 AB433_18080
CMAN:	A9D14_12795 A9D14_14980
PNS:	A9D12_04810
PORL:	BG023_11372
AMV:	ACMV_P1_01400
KEU:	S101446_03116(hcaD)
ASZ:	ASN_576
AZL:	AZL_a06740(hcaD) AZL_b01740
ALI:	AZOLI_p11027 AZOLI_p20650
ABS:	AZOBR_p330134
ABQ:	ABAZ39_27955
TMO:	TMO_a0555(thcD) TMO_b0125(thcD) TMO_c0277(thcD)
MAGQ:	MGMAQ_2659
PBR:	PB2503_11479
PGV:	SL003B_0452 SL003B_2136 SL003B_3178 SL003B_4079 SL003B_4108
APB:	SAR116_2170
LAO:	AOX59_16850
LBT:	AYR52_12745
MTU:	Rv1869c
MTV:	RVBD_1869c
MTC:	MT1918
MRA:	MRA_1880
MTF:	TBFG_11897
MTB:	TBMG_02125
MTK:	TBSG_02136
MTZ:	TBXG_002107
MTG:	MRGA327_11545
MTI:	MRGA423_11670
MTE:	CCDC5079_1726
MTUR:	CFBS_1961
MTL:	CCDC5180_1704
MTO:	MTCTRI2_1901
MTD:	UDA_1869c
MTN:	ERDMAN_2061
MTJ:	J112_09960
MTUB:	MT7199_1895
MTUC:	J113_12960
MTUE:	J114_09960
MTX:	M943_09710
MTUL:	TBHG_01824
MTUT:	HKBT1_1958
MTUU:	HKBT2_1966
MTQ:	HKBS1_1962
MBO:	Mb1900c
MBB:	BCG_1905c
MBT:	JTY_1889
MBM:	BCGMEX_1886c
MBK:	K60_019560
MBX:	BCGT_1702
MBZ:	LH58_10020
MAF:	MAF_18910
MCE:	MCAN_18841
MCQ:	BN44_40132
MCV:	BN43_31010
MCX:	BN42_30134
MCZ:	BN45_50134
MMIC:	RN08_2074
MPA:	MAP_1579c
MAO:	MAP4_2260
MAVI:	RC58_11240
MAVU:	RE97_11250
MAV:	MAV_2849
MAVD:	NF84_12705
MAVR:	LA63_12860
MAVA:	LA64_12850
MIT:	OCO_23020 OCO_26790
MIA:	OCU_26650
MIE:	LG41_12640
MIR:	OCQ_25350 OCQ_28970
MID:	MIP_03989
MYO:	OEM_25310
MCHI:	AN480_04250 AN480_14090
MSM:	MSMEG_1460 MSMEG_3594
MSG:	MSMEI_1424 MSMEI_3512
MSB:	LJ00_07295 LJ00_17885
MSN:	LI99_07295 LI99_17890
MSH:	LI98_07295 LI98_17895
MSA:	Mycsm_01990 Mycsm_03302
MVA:	Mvan_0400 Mvan_1327
MGI:	Mflv_4591
MAB:	MAB_0913c MAB_2047c
MAY:	LA62_04615 LA62_10425 LA62_22195
MABO:	NF82_04610 NF82_10225 NF82_21885
MAZ:	LA61_04525 LA61_10315 LA61_22090
MIZ:	BAB75_00160 BAB75_11005
MMC:	Mmcs_3219
MKM:	Mkms_3281
MJL:	Mjls_3230
MJD:	JDM601_1956
MMI:	MMAR_3153
MRH:	MycrhN_0184 MycrhN_3132 MycrhN_4857 MycrhN_5186
MMM:	W7S_13005
MCB:	Mycch_5831
MKN:	MKAN_00605
MKS:	LG40_00615
MKI:	LH54_00625
MNE:	D174_06780 D174_15650
MYV:	G155_08415 G155_16390 G155_23245
MYE:	AB431_15765
MGO:	AFA91_19865 AFA91_21905 AFA91_26610 AFA91_31600
MFT:	XA26_16840 XA26_33580
MHAD:	B586_11635
MPHL:	MPHLCCUG_01328(thcD)
MVQ:	MYVA_1135
ASD:	AS9A_2814 AS9A_4288
CGU:	WA5_0525 WA5_2615
CGS:	C624_03360 C624_13300
CGG:	C629_03360 C629_13305
CGM:	cgp_0639 cgp_2999
CGJ:	AR0_03360 AR0_13135
CGQ:	CGLAR1_03220 CGLAR1_13000
CGX:	SB89_02975 SB89_12765
CDR:	CDHC03_1954(hcaD)
CVA:	CVAR_0135
CHN:	A605_02625
CTER:	A606_11495
CMD:	B841_09420
CAZ:	CARG_03220
CCG:	CCASEI_11950
CGY:	CGLY_01060
CII:	CIMIT_11740
CMV:	CMUST_15090(hcaD)
CSTA:	CSTAT_10855
CCJZ:	ccrud_02795 ccrud_12210
BFV:	C628_03195 C628_13420
NFA:	NFA_12150
NFR:	ERS450000_00301(thcD_1) ERS450000_00667(thcD_2) ERS450000_02785(thcD_3) ERS450000_02895(thcD_4)
NCY:	NOCYR_1335 NOCYR_1540(camA) NOCYR_2728
NBR:	O3I_008695
NNO:	NONO_c29040 NONO_c33120 NONO_c46210 NONO_c61150
NSL:	BOX37_06545 BOX37_15235 BOX37_27385 BOX37_27690
NSR:	NS506_05423 NS506_06930
RHA:	RHA1_ro01813 RHA1_ro02383 RHA1_ro02509 RHA1_ro02537 RHA1_ro04374 RHA1_ro06050 RHA1_ro08162(padAd) RHA1_ro08163(padAc) RHA1_ro08179(tpaB1) RHA1_ro08637 RHA1_ro08986 RHA1_ro10125(etbAd) RHA1_ro10196(tpaB) RHA1_ro10212(padAc) RHA1_ro10213(padAd) RHA1_ro11067
RER:	RER_pREL1-02840
REY:	O5Y_03645 O5Y_17660
REB:	XU06_03885 XU06_17870 XU06_30725 XU06_31870
ROP:	ROP_42790 ROP_45680 ROP_53800(thcD) ROP_70800
ROA:	Pd630_LPD00822 Pd630_LPD05499 Pd630_LPD06762 Pd630_LPD06952
REQ:	REQ_30110 REQ_35080
RPY:	Y013_00525 Y013_18115
RAV:	AAT18_02390 AAT18_09350 AAT18_10875 AAT18_22460
RFA:	A3L23_01169(thcD_1) A3L23_05141(camA)
RHW:	BFN03_10760 BFN03_15850
GPO:	GPOL_c02210 GPOL_c08470 GPOL_c48190
GOR:	KTR9_1267 KTR9_2918 KTR9_5381
GOQ:	ACH46_18920 ACH46_19575
GTA:	BCM27_00590 BCM27_14980
DTM:	BJL86_2109
SGB:	WQO_10105
SSX:	SACTE_1921
SVL:	Strvi_4591 Strvi_7637
SCT:	SCAT_1535
SCY:	SCATT_15370
SFA:	Sfla_4382
SBH:	SBI_00328 SBI_07356(fprD)
SHY:	SHJG_3945
SHO:	SHJGH_3710
SVE:	SVEN_2257
SDV:	BN159_5856
SALB:	XNR_4478
SALS:	SLNWT_0025 SLNWT_0906 SLNWT_5405 SLNWT_6894 SLNWT_6903
STRP:	F750_2319
SFI:	SFUL_2016
SCI:	B446_12720
SRC:	M271_33065
SALU:	DC74_2995 DC74_8061
SALL:	SAZ_16005 SAZ_41630
SLV:	SLIV_00970 SLIV_03690 SLIV_25340
SGU:	SGLAU_11300
SVT:	SVTN_12215
STRE:	GZL_05962
SCW:	TU94_10650
SLD:	T261_5627 T261_7130
SXI:	SXIM_14100
STRM:	M444_04355 M444_12235 M444_32855
STRC:	AA958_08940
SAMB:	SAM23877_2522
SPRI:	SPRI_5040 SPRI_6481
SCZ:	ABE83_25825
SCX:	AS200_30225
SRW:	TUE45_03065(camA)
STRF:	ASR50_01260 ASR50_11945 ASR50_34185
SLE:	sle_47430(sle_47430)
SRN:	A4G23_01569(andAa)
SPAV:	Spa2297_10420
SLC:	SL103_06765
STRT:	A8713_09570
SCLF:	BB341_19910
SGS:	AVL59_39415
STSI:	A4E84_12920 A4E84_36420
SLS:	SLINC_2851
SNR:	SNOUR_28015
SPLU:	LK06_009165
STRD:	NI25_26655 NI25_36285
SNW:	BBN63_09150 BBN63_24235
KSK:	KSE_18230 KSE_18360
MIO:	AOA12_00395 AOA12_02550 AOA12_16370 AOA12_18560
MIX:	AB663_001490
MCW:	A8L33_08945
MVD:	AWU67_11495
AGY:	ATC03_06320
CART:	PA27867_2785
ART:	Arth_1999 Arth_4345
ARR:	ARUE_c18900 ARUE_c28650
ARM:	ART_0347 ART_1724
ARL:	AFL94_13935 AFL94_14240 AFL94_15820
ARE:	AL755_16535
ARH:	AHiyo8_54660 AHiyo8_54670 AHiyo8_pI68190
ARY:	ATC04_02120 ATC04_03700 ATC04_04025 ATC04_11660 ATC04_14585
ARW:	MB46_11740
ARZ:	AUT26_13360 AUT26_19540
AAU:	AAur_pTC10068
APN:	Asphe3_17600
PSUL:	AU252_18125
AAI:	AARI_27120 AARI_27900
GAR:	AOZ07_03920 AOZ07_13955 AOZ07_14295
KPL:	KPaMU14_05385
KFV:	AS188_11690
MLU:	Mlut_20060
SATK:	SA2016_3863
NAE:	BHE16_09195
LMOI:	VV02_12055
IDO:	I598_2943(thcD)
CET:	B8281_01910 B8281_06840
CCEU:	CBR64_04550
CFI:	Celf_2109
JTE:	ASJ30_16020
BLY:	A2T55_02920 A2T55_06725 A2T55_08545
BLIN:	BLSMQ_0484 BLSMQ_1826
PBO:	PACID_32500
AACI:	ASQ49_05935
TFA:	BW733_11635
TES:	BW730_11415
NCA:	Noca_0832 Noca_4282
NDK:	I601_1173(thcD) I601_3166(camA_2)
AER:	AERYTH_02535 AERYTH_04700
SRO:	Sros_1897
NOA:	BKM31_13315 BKM31_22565 BKM31_32545
FRA:	Francci3_3074
FRI:	FraEuI1c_3228
FAL:	FRAAL3171 FRAAL4010(fprC)
FSY:	FsymDg_2024
ACE:	Acel_0803
NML:	Namu_3641
SEN:	SACE_2839(fprC) SACE_3145(fprC) SACE_3433 SACE_4511(fprC) SACE_5609(padAd2)
AMD:	AMED_0391(hcaD) AMED_4383
AMN:	RAM_02005 RAM_22320
AMM:	AMES_0391(hcaD) AMES_4329
AMZ:	B737_0392(hcaD) B737_4329
AOI:	AORI_0410(hcaD) AORI_3258(hcaD) AORI_6047
AJA:	AJAP_22905(andAa) AJAP_37605(thcD)
AMQ:	AMETH_0220(hcaD) AMETH_3239 AMETH_5363(fprD) AMETH_6105
ALU:	BB31_13750 BB31_39710
PDX:	Psed_0810 Psed_1441
PSEA:	WY02_20120
PHH:	AFB00_24055
SESP:	BN6_12600
KAL:	KALB_1398
KPHY:	AOZ06_13865
LED:	BBK82_02520
ALL:	CRK55028
AFS:	AFR_27755
CAI:	Caci_2641
RXY:	Rxyl_2822
RRD:	RradSPS_2062
AVA:	Ava_2874
PHM:	PSMK_20850
RSI:	Runsl_0438
EOL:	Emtol_3253
FLM:	MY04_2083
MARM:	YQ22_01785
CAO:	Celal_3018
CLY:	Celly_2487
CLH:	IX49_12480
CBAL:	M667_11695
CBAT:	M666_11740
ZGA:	ZOBELLIA_4675
PRN:	BW723_04390
WFU:	AXE80_13405
HMA:	rrnAC0717
NPH:	NP_4516A
HWA:	HQ_1120A HQ_3319A

» show all

Reference

PMID:9603882

Authors

Diaz E, Ferrandez A, Garcia JL.

Title

Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.

Journal

J Bacteriol 180:2915-23 (1998)

LinkDB

ENZYME: 1.14.12.19

Entry

EC 1.14.12.19 Enzyme

Name

3-phenylpropanoate dioxygenase;
HcaA1A2CD;
Hca dioxygenase;
3-phenylpropionate dioxygenase

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor

Sysname

3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating)

Reaction(IUBMB)

(1) 3-phenylpropanoate + NADH + H+ + O2 = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+ [RN:R06782];
(2) (2E)-3-phenylprop-2-enoate + NADH + H+ + O2 = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + NAD+

Reaction(KEGG)

R06782;
(other) R06783

Substrate

3-phenylpropanoate;
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007];
(2E)-3-phenylprop-2-enoate [CPD:C00423]

Product

3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate [CPD:C11588];
NAD+ [CPD:C00003];
(2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate [CPD:C12623]

Comment

This enzyme catalyses a step in the pathway of phenylpropanoid compounds degradation. It catalyses the insertion of both atoms of molecular oxygen into positions 2 and 3 of the phenyl ring of 3-phenylpropanoate or (2E)-3-phenylprop-2-enoate.

History

EC 1.14.12.19 created 2005, modified 2011

Pathway

ec00360	Phenylalanine metabolism
ec01120	Microbial metabolism in diverse environments

Orthology

K05708	3-phenylpropionate/trans-cinnamate dioxygenase subunit alpha
K05709	3-phenylpropionate/trans-cinnamate dioxygenase subunit beta

Genes

ECO:	b2538(hcaE) b2539(hcaF)
ECJ:	JW2522(hcaE) JW2523(hcaF)
ECD:	ECDH10B_2705(hcaE) ECDH10B_2706(hcaF)
EBW:	BWG_2302(hcaE) BWG_2303(hcaF)
ECOK:	ECMDS42_2082(hcaE) ECMDS42_2083(hcaF)
ECE:	Z3809(hcaA1) Z3810(hcaA2)
ECS:	ECs3404 ECs3405
ECF:	ECH74115_3771(hcaF)
ETW:	ECSP_3482(hcaE) ECSP_3483(hcaF)
ELX:	CDCO157_3171 CDCO157_3172
EOJ:	ECO26_3585(hcaE) ECO26_3586(hcaF)
EOI:	ECO111_3262(hcaE) ECO111_3263(hcaF)
EOH:	ECO103_3055(hcaE)
EOK:	G2583_3068(hcaE) G2583_3069(hcaF)
ELR:	ECO55CA74_15185 ECO55CA74_15190
ECX:	EcHS_A2690(hcaE) EcHS_A2691(hcaF)
ECW:	EcE24377A_2824(hcaF)
ECM:	EcSMS35_2691(hcaE) EcSMS35_2692(hcaF)
ECY:	ECSE_2825 ECSE_2826
ECR:	ECIAI1_2590(hcaE) ECIAI1_2591(hcaF)
ECK:	EC55989_2824(hcaE) EC55989_2825(hcaF)
ECT:	ECIAI39_2739(hcaE) ECIAI39_2740(hcaF)
EOC:	CE10_2970(hcaE) CE10_2971(hcaF)
EUM:	ECUMN_2858(hcaE) ECUMN_2859(hcaF)
ELO:	EC042_2742(hcaE) EC042_2743(hcaF)
ELH:	ETEC_2695 ETEC_2696
ESO:	O3O_18925 O3O_18930
ESM:	O3M_06765 O3M_06770
ESL:	O3K_06720 O3K_06725
ECL:	EcolC_1138 EcolC_1139
EBR:	ECB_02430(hcaE) ECB_02431(hcaF)
EBD:	ECBD_1145 ECBD_1146
EKO:	EKO11_1194 EKO11_1195
EKF:	KO11_10125(hcaF) KO11_10130(hcaE)
EDH:	EcDH1_1129 EcDH1_1130
EDJ:	ECDH1ME8569_2465(hcaE) ECDH1ME8569_2466(hcaF)
EUN:	UMNK88_3191 UMNK88_3192
ELW:	ECW_m2764(hcaE) ECW_m2765(hcaF)
ELL:	WFL_13535(hcaE) WFL_13540(hcaF)
ELP:	P12B_c2638(hcaA) P12B_c2639(hcaF)
EBL:	ECD_02430(hcaE) ECD_02431(hcaF)
EBE:	B21_02394(hcaE) B21_02395(hcaF)
ECOA:	APECO78_16420 APECO78_16425
ECOL:	LY180_13020 LY180_13025
ECOO:	ECRM13514_3370(hcaA1) ECRM13514_3371(hcaA2)
ECOH:	ECRM13516_3226(hcaA1) ECRM13516_3227(hcaA2)
SFL:	SF2585(hcaA1) SF2586(hcaA2)
SFX:	S2757(hcaA1) S2758(hcaA2)
SFV:	SFV_2586(hcaA1) SFV_2587(hcaA2)
SFE:	SFxv_2841(hcaE) SFxv_2842(hcaF)
SFN:	SFy_3672 SFy_3673
SFS:	SFyv_3749 SFyv_3750
SFT:	NCTC1_02841(hcaA1) NCTC1_02842(hcaA2)
SSN:	SSON_2620(hcaA1) SSON_2621(hcaA2)
SBO:	SBO_2562(hcaA1) SBO_2563(hcaA2)
SHQ:	A0259_16415 A0259_16420
KPV:	KPNIH29_19720 KPNIH29_19725
CFD:	CFNIH1_24125 CFNIH1_24130
CIF:	AL515_17210 AL515_17215
KGO:	CEW81_06275
EBF:	D782_1130 D782_1131
SFW:	WN53_15140 WN53_15145
SFG:	AV650_10680 AV650_10685
PLU:	plu2204(hcaE) plu2205(hcaF)
PAY:	PAU_02356(hcaF) PAU_02357(hcaE)
PTT:	VY86_20035 VY86_20040
VNA:	PN96_06440 PN96_06445
VEJ:	VEJY3_06605 VEJY3_06610
VFU:	vfu_A01965 vfu_A01966
AEI:	AOY20_01945 AOY20_01950
ASJ:	AsACE_CH00358(hcaE) AsACE_CH00359(hcaF)
CYQ:	Q91_0870 Q91_2056 Q91_2174
CZA:	CYCME_0248 CYCME_0369
WOC:	BA177_04185
GBI:	PG2T_03650 PG2T_03670 PG2T_10655 PG2T_11305 PG2T_14655
AQL:	BXU06_16230 BXU06_16235
BCEN:	DM39_1983
BDF:	WI26_30250 WI26_30255
BPLA:	bpln_1g12620
AFA:	UZ73_04210 UZ73_04215
DEL:	DelCs14_1743
RBU:	PG1C_02395
NAR:	Saro_3840
NPP:	PP1Y_AT31297
SPHP:	LH20_03925
SWI:	Swit_0890
AAY:	WYH_01869(hcaE)
PNP:	IJ22_07010
MSA:	Mycsm_01912 Mycsm_01988
MVA:	Mvan_4415
MAB:	MAB_4370c
MAY:	LA62_22205
MABO:	NF82_21895
MAZ:	LA61_22100
MFT:	XA26_16860
CDR:	CDHC03_1952(hcaE)
CAZ:	CARG_03210 CARG_03270
CII:	CIMIT_11730
CMV:	CMUST_15080(hcaE)
NFR:	ERS450000_00303(hcaE_2)
NNO:	NONO_c29020
REB:	XU06_31885
REQ:	REQ_35060
RAV:	AAT18_09365
GOR:	KTR9_1265
DTM:	BJL86_0371
SCB:	SCAB_2191(hcaE)
STSI:	A4E84_36430
MIO:	AOA12_18550
NAE:	BHE16_09185
FRI:	FraEuI1c_4097
TRO:	trd_A0341
SAI:	Saci_2059
SACR:	SacRon12I_10260
SACS:	SUSAZ_05365 SUSAZ_09335
SIS:	LS215_0748
SIA:	M1425_0846
SIM:	M1627_0911
SID:	M164_0864
SIY:	YG5714_0780
SII:	LD85_0977
SIH:	SiH_0732

» show all

Reference

1 [PMID:9603882]

Authors

Diaz E, Ferrandez A, Garcia JL.

Title

Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.

Journal

J. Bacteriol. 180 (1998) 2915-23.

Sequence

[eco:b2538 b2539]

Reference

2 [PMID:6345502]

Authors

Burlingame R, Chapman PJ.

Title

Catabolism of phenylpropionic acid and its 3-hydroxy derivative by Escherichia coli.

Journal

J. Bacteriol. 155 (1983) 113-21.

Other DBs

ExplorEnz - The Enzyme Database:

1.14.12.19

IUBMB Enzyme Nomenclature:

1.14.12.19

ExPASy - ENZYME nomenclature database:

1.14.12.19

UM-BBD (Biocatalysis/Biodegradation Database):

1.14.12.19

BRENDA, the Enzyme Database:

1.14.12.19

LinkDB

REACTION: R06782

Entry

R06782 Reaction

Name

3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating)

Definition

Phenylpropanoate + Oxygen + NADH + H+ <=> cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol + NAD+

Equation

C05629 + C00007 + C00004 + C00080 <=> C11588 + C00003

Comment

HcaA1 HcaA2 HcaC HcaD

Reaction class

RC00001	C00003_C00004
RC00098	C05629_C11588

Enzyme

1.14.12.19

Pathway

rn00360	Phenylalanine metabolism
rn01120	Microbial metabolism in diverse environments
rn01220	Degradation of aromatic compounds

Orthology

K00529	3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
K05708	3-phenylpropionate/trans-cinnamate dioxygenase subunit alpha [EC:1.14.12.19]
K05709	3-phenylpropionate/trans-cinnamate dioxygenase subunit beta [EC:1.14.12.19]
K05710	3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component

Other DBs

RHEA:

20360

LinkDB

DBGET integrated database retrieval system