KEGG   ORTHOLOGY: K05712Help
Entry
K05712                      KO                                     

Name
mhpA
Definition
3-(3-hydroxy-phenyl)propionate hydroxylase [EC:1.14.13.127]
Pathway
Phenylalanine metabolism
Degradation of aromatic compounds
Module
M00545  
Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Overview
   01220 Degradation of aromatic compounds
    K05712  mhpA; 3-(3-hydroxy-phenyl)propionate hydroxylase
  Amino acid metabolism
   00360 Phenylalanine metabolism
    K05712  mhpA; 3-(3-hydroxy-phenyl)propionate hydroxylase
KEGG modules [BR:ko00002]
 Pathway module
  Nucleotide and amino acid metabolism
   Aromatic amino acid metabolism
    M00545  Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
     K05712  mhpA; 3-(3-hydroxy-phenyl)propionate hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.127  3-(3-hydroxyphenyl)propanoate hydroxylase
     K05712  mhpA; 3-(3-hydroxy-phenyl)propionate hydroxylase
BRITE hierarchy
Other DBs
Genes
ECO: 
b0347(mhpA)
ECJ: 
JW0338(mhpA)
ECD: 
ECOK: 
ECE: 
Z0445(mhpA)
ECS: 
ECs0402(mhpA)
ECF: 
ETW: 
ECSP_0411(mhpA)
ELX: 
EOJ: 
EOI: 
ECO111_0383(mhpA)
EOH: 
ECO103_0329(mhpA)
EOK: 
G2583_0460(mhpA)
ELR: 
ECO55CA74_02210(mhpA)
ECX: 
EcHS_A0411(mhpA)
ECW: 
EcE24377A_0371(mhpA)
ECM: 
EcSMS35_0378(mhpA)
ECY: 
ECSE_0372
ECR: 
ECIAI1_0348(mhpA)
ECQ: 
ECED1_0375(mhpA)
ECK: 
EC55989_0354(mhpA)
ECT: 
ECIAI39_0331(mhpA)
EOC: 
CE10_0315(mhpA)
EUM: 
ECUMN_0390(mhpA)
ELO: 
EC042_0384(mhpA)
ELH: 
ETEC_0403
ESE: 
ECSF_0318
ESO: 
O3O_05555(mhpA)
ESM: 
O3M_19725(mhpA)
ESL: 
O3K_19740(mhpA)
ECL: 
EcolC_3278
EBR: 
ECB_00301(mhpA)
EBD: 
ECBD_3310
EKO: 
EKO11_3495
EKF: 
KO11_21845(mhpA)
EDH: 
EcDH1_3259
EDJ: 
ECDH1ME8569_0334(mhpA)
ENA: 
ECNA114_0330(mhpA)
EUN: 
UMNK88_397
ELW: 
ECW_m0425(mhpA)
ELL: 
WFL_02090(mhpA)
ELP: 
P12B_c0307(mhpA) P12B_c0365(mhpA)
EBL: 
ECD_00301(mhpA)
EBE: 
B21_00305(mhpA)
ECOA: 
APECO78_05255
ECOL: 
LY180_02125(mhpA)
ECOJ: 
P423_01825(mhpA)
ECOO: 
ECRM13514_0499(mhpA)
ECOH: 
ECRM13516_0327(mhpA)
ECOS: 
EC958_0491
SSN: 
SSON_0297(mhpA)
SHQ: 
A0259_05405(mhpA)
KPN: 
KPN_02122(mhpA)
KPU: 
KP1_3217(mhpA)
KPM: 
KPHS_31050
KPP: 
A79E_2122
KPK: 
A593_25665(mhpA)
KPH: 
KPNIH24_12930(mhpA)
KPZ: 
KPNIH27_14865(mhpA)
KPV: 
KPNIH29_15525(mhpA)
KPW: 
KPNIH30_15805(mhpA)
KPY: 
KPNIH31_14660(mhpA)
KPG: 
KPNIH32_15700(mhpA)
KPC: 
KPNIH10_15325(mhpA)
KPQ: 
KPR0928_15300(mhpA)
KPT: 
VK055_0339(mhpA)
KPE: 
KPK_2201(mhpA)
KPO: 
KPN2242_13565(mhpA)
KPR: 
KPR_2667 KPR_2668
KPJ: 
N559_2167
KPI: 
D364_10875(mhpA)
KPA: 
KPNJ1_02340
KPS: 
KPNJ2_02300
KPX: 
PMK1_04486(mhpA)
KPB: 
FH42_06705(mhpA)
KPNE: 
KU54_010815(mhpA)
KPNU: 
LI86_10770(mhpA)
KVA: 
Kvar_2153
KVD: 
KR75_23585(mhpA)
KVQ: 
SP68_04240(mhpA)
KOX: 
KOX_22695(mhpA)
KOE: 
A225_3416
KOY: 
J415_14950(mhpA)
KOK: 
KONIH1_16730(mhpA)
KOC: 
AB185_19175(mhpA)
KOM: 
HR38_20990(mhpA)
KQU: 
AVR78_19690(mhpA)
CFD: 
CFNIH1_11830(mhpA)
CIF: 
AL515_06435(mhpA)
EBT: 
EBL_c20040(mhpA1)
ROR: 
RORB6_04275(mhpA)
PGE: 
LG71_09620(mhpA)
KGO: 
CEW81_11370(mhpA)
EBF: 
D782_1982
SLQ: 
M495_12025
PLU: 
plu1437
PAY: 
PAU_02254
LEZ: 
GLE_5300
VNA: 
PN96_06275(mhpA)
VEJ: 
VEJY3_06780(mhpA)
VFU: 
vfu_A01977
PCQ: 
PcP3B5_43040(mhpA_3)
PPW: 
PputW619_1979
PPUN: 
PP4_19460
PFV: 
Psefu_2046
PSYR: 
N018_13885
PFS: 
PFLU_3081 PFLU_4110
PFE: 
PSF113_2094 PSF113_2493 PSF113_3456
PFW: 
PF1751_v1c35480
PFF: 
PFLUOLIPICF718150
PPZ: 
H045_07775(mhpA)
PCG: 
AXG94_01855
PVR: 
PverR02_10450 PverR02_12315(mhpA) PverR02_20750
PSTT: 
CH92_04330
PBA: 
PSEBR_a2350 PSEBR_a3645
PBC: 
CD58_10880 CD58_17315
PPUU: 
PputUW4_02144(mhpA)
PSK: 
U771_16375 U771_21540
PSW: 
LK03_20495
PPSY: 
AOC04_16940(mhpA)
PFK: 
PFAS1_24645
AEI: 
AOY20_07915(mhpA)
OSG: 
BST96_04145 BST96_04525 BST96_17355
WOC: 
BA177_04230
HCS: 
FF32_04635
HAK: 
KO116_03916
HCO: 
LOKO_00974(pcpB) LOKO_00984(mhpA)
ADI: 
B5T_01229
APAC: 
S7S_05355
MARS: 
A8C75_10110
SEDS: 
AAY24_02880
RSO: 
RSp0702
RSL: 
RPSI07_mp0600
RSN: 
RSPO_m01032(ubiF)
RSM: 
CMR15_mp10673
RSE: 
F504_4517
RPI: 
Rpic_4529
RPF: 
Rpic12D_4661
RPJ: 
N234_23045 N234_29540 N234_30015 N234_30845 N234_34290
RMN: 
TK49_12795 TK49_17220
RIN: 
ACS15_1388 ACS15_4654
REU: 
Reut_A0270 Reut_B4218 Reut_B5321 Reut_B5808
REH: 
H16_B0971(h16_B0971) H16_B1546(h16_B1546) H16_B2557(h16_B2557)
CNC: 
CNE_2c15470(mhpA1) CNE_2c24670(mhpA2) CNE_BB1p14220(mhpA)
RME: 
Rmet_0339
CTI: 
RALTA_B1347 RALTA_B2288
CBW: 
RR42_m3020 RR42_s0346 RR42_s1475
CGD: 
CR3_3181(mhpA) CR3_4109(mhpA)
CCUP: 
BKK81_18745 BKK81_21915 BKK81_23890
BMA: 
BMA2059
BMV: 
BMASAVP1_A0853
BML: 
BMA10229_A2685
BMN: 
BMA10247_1924
BMAL: 
DM55_2396
BMAE: 
DM78_2627
BMAQ: 
DM76_2381
BMAI: 
DM57_847
BMAF: 
DM51_1717
BMAZ: 
BM44_1291
BMAB: 
BM45_853
BPS: 
BPSL2532 BPSL2742
BPM: 
BURPS1710b_3014(mtmOII) BURPS1710b_3231
BPL: 
BURPS1106A_3216
BPD: 
BURPS668_3177
BPR: 
GBP346_A3356
BPSE: 
BDL_2704
BPSM: 
BBQ_569
BPSU: 
BBN_697
BPSD: 
BBX_1102
BPZ: 
BP1026B_I0573
BPQ: 
BPC006_I3259
BPK: 
BBK_2190
BPSH: 
DR55_1776
BPSA: 
BBU_2821
BPSO: 
X996_1416
BUT: 
X994_3416 X994_5940
BTE: 
BTH_I1395
BTQ: 
BTQ_2538
BTJ: 
BTJ_3156
BTZ: 
BTL_1087
BTD: 
BTI_862
BTV: 
BTHA_1179
BTHE: 
BTN_301
BTHM: 
BTRA_1295
BTHA: 
DR62_467
BTHL: 
BG87_1284
BOK: 
DM82_1354 DM82_2409
BOC: 
BG90_2324 BG90_3340
BVI: 
Bcep1808_0754 Bcep1808_5388 Bcep1808_5589
BVE: 
AK36_3498(mhpA) AK36_5080 AK36_51
BUR: 
Bcep18194_A3910 Bcep18194_A4123 Bcep18194_A4483
BCN: 
Bcen_0334 Bcen_5086 Bcen_6487
BCH: 
Bcen2424_0161 Bcen2424_0817 Bcen2424_5774 Bcen2424_6722
BCM: 
Bcenmc03_0786 Bcenmc03_4404
BCJ: 
BCAL1339 BCAL2996 BCAL3187 BCAM0077
BCEN: 
DM39_4116 DM39_4971 DM39_628 DM39_6548 DM39_846
BCEW: 
DM40_1483 DM40_5004(mhpA) DM40_5334
BCEO: 
I35_0670 I35_0874 I35_1234(mhpA) I35_4084(mhpA)
BAM: 
Bamb_0698 Bamb_0875 Bamb_4304
BAC: 
BamMC406_0715
BMU: 
Bmul_2566 Bmul_5805
BMJ: 
BMULJ_00672(mhpA) BMULJ_05717
BMK: 
DM80_6252 DM80_868
BMUL: 
NP80_3429 NP80_5229 NP80_833
BCT: 
GEM_2509 GEM_2711
BCED: 
DM42_1012 DM42_370 DM42_5077 DM42_818
BCEP: 
APZ15_07725 APZ15_08755 APZ15_10450
BDL: 
AK34_2355
BPYR: 
ABD05_09705 ABD05_33420
BCON: 
NL30_10610 NL30_11700 NL30_35890
BUB: 
BW23_920
BDF: 
WI26_03590 WI26_04540 WI26_30210
BLAT: 
WK25_03795 WK25_17345 WK25_27500
BTEI: 
WS51_00135 WS51_14365 WS51_15300
BSEM: 
WJ12_03695 WJ12_04670 WJ12_19400 WJ12_20050 WJ12_26040
BPSL: 
WS57_02980 WS57_12795 WS57_21495 WS57_22605
BMEC: 
WJ16_03730 WJ16_04700 WJ16_18530
BSTG: 
WT74_03995
BGL: 
bglu_2g00750
BGU: 
KS03_3563
BUG: 
BC1001_3698 BC1001_4373 BC1001_4612
BGE: 
BC1002_3962 BC1002_4181 BC1002_4724 BC1002_5806 BC1002_5811 BC1002_6621
BGF: 
BC1003_4885
BGD: 
bgla_1g15130 bgla_2g09170
BYI: 
BYI23_B003840
BUK: 
MYA_0708 MYA_5006 MYA_5137
BUO: 
BRPE64_BCDS09430
BUE: 
BRPE67_BCDS06410
BUL: 
BW21_2674 BW21_957
BUQ: 
AC233_20465 AC233_26985
BUD: 
AQ610_04190 AQ610_12650
BXE: 
Bxe_A2727 Bxe_B0428 Bxe_B1226 Bxe_B2329 Bxe_C0990
BXB: 
DR64_410 DR64_4661(mhpA) DR64_5764 DR64_6541 DR64_7461
BPH: 
Bphy_3513 Bphy_4050 Bphy_4192 Bphy_4535
BPX: 
BUPH_00265 BUPH_01175 BUPH_02477 BUPH_02488
BPY: 
Bphyt_5380 Bphyt_7215
BFN: 
OI25_6133 OI25_6980
BCAI: 
K788_0000774 K788_0001102
PSPW: 
BJG93_23975
PPK: 
U875_05840 U875_20200 U875_21900
PPNO: 
DA70_11715 DA70_12890 DA70_14580 DA70_22915
PPNM: 
LV28_07795 LV28_16105 LV28_17810 LV28_19235
PRB: 
X636_03735 X636_12265 X636_13980 X636_15115
PPUL: 
RO07_10205 RO07_12005
PSPU: 
NA29_06040 NA29_07810 NA29_08025
PAPI: 
SG18_10635 SG18_12335 SG18_24440
PVE: 
UC34_01905 UC34_03855 UC34_22405
POX: 
MB84_06345 MB84_08310
PTX: 
ABW99_01685 ABW99_04580 ABW99_12955 ABW99_20645
PFG: 
AB870_09220 AB870_13125 AB870_14930
PNR: 
AT302_09960 AT302_12120
BPE: 
BP3131
BPC: 
BPTD_3093
BPER: 
BN118_2796
BPET: 
B1917_0691
BPEU: 
Q425_31090
BPA: 
BPP0811
BPAR: 
BN117_0841
BBR: 
BB0895
BBM: 
BN115_0864
BBH: 
BN112_2547
BBX: 
BBS798_0868
BPT: 
Bpet0304 Bpet4008
BAV: 
BAV0531 BAV3126
BHO: 
D560_0451 D560_1693
BHM: 
D558_0449 D558_0450 D558_1682
BHZ: 
ACR54_00736(mhpA_1) ACR54_04380(mhpA_2) ACR54_04635(mhpA_3)
BTRM: 
SAMEA390648701822(mhpA)
BBRO: 
BAU06_02065
AXY: 
AXYL_00831 AXYL_00862 AXYL_02650 AXYL_03052(mhpA) AXYL_05594
AXO: 
NH44784_012811 NH44784_028501 NH44784_029771
AXN: 
AX27061_0876 AX27061_5341 AX27061_5466
AXS: 
LH59_04350 LH59_24580 LH59_25190
AXX: 
ERS451415_00865(mhpA_1) ERS451415_05371(mhpA_2) ERS451415_05492(mhpA_3)
ADT: 
APT56_04615 APT56_24535
AIS: 
BUW96_03325 BUW96_05370 BUW96_16675 BUW96_21370
PUT: 
PT7_2127
AMIM: 
MIM_c24060
CDN: 
BN940_02586
AFA: 
UZ73_07715
RHY: 
RD110_22340 RD110_22775
POL: 
Bpro_3000 Bpro_3718 Bpro_4535
PNA: 
Pnap_0616
AAA: 
Acav_1712
ACK: 
C380_21505
ACID: 
CBP33_04160
VEI: 
Veis_3422 Veis_3440 Veis_4632
DAC: 
Daci_0579 Daci_4008
DEL: 
DelCs14_0524 DelCs14_2791
DTS: 
BI380_06055 BI380_24540
DHK: 
BO996_00370 BO996_18345
VAP: 
Vapar_0291 Vapar_4781 Vapar_5105
VPE: 
Varpa_0301 Varpa_5439 Varpa_5826
VPD: 
VAPA_1c03530 VAPA_1c49470 VAPA_1c52960 VAPA_2c06770 VAPA_2c10690
CTT: 
CtCNB1_2361 CtCNB1_4501
CTES: 
O987_15285 O987_26695
CKE: 
B5M06_13690
RTA: 
Rta_01740 Rta_31330
LIM: 
L103DPR2_02457(mhpA_1) L103DPR2_02630(mhpA_2)
LIH: 
L63ED372_01280(mhpA_1) L63ED372_02668(mhpA_2)
HYR: 
BSY239_1873 BSY239_500
HYB: 
Q5W_11565 Q5W_15790
HYL: 
LPB072_08090 LPB072_18410
CBAA: 
SRAA_1361
JAZ: 
YQ44_11050
JAL: 
BZG29_16540
HSE: 
Hsero_0543 Hsero_1553 Hsero_3945(mhpA)
HSZ: 
ACP92_02705 ACP92_07800 ACP92_19680
HHT: 
F506_11265
HRB: 
Hrubri_0531 Hrubri_1454
MASW: 
AM586_03095
LCH: 
Lcho_4300
TIN: 
Tint_2994
THI: 
THI_3545
RDP: 
RD2015_1541
PKT: 
AT984_13220
MIU: 
ABE85_00305
SHD: 
SUTH_02820(mhpA)
EBA: 
ebA3297
AZO: 
azo3681(mhpA)
AZA: 
AZKH_2696 AZKH_4363
AZI: 
AzCIB_1299 AzCIB_4301
TMZ: 
Tmz1t_0850
TCL: 
Tchl_0093 Tchl_1491
APP: 
CAP2UW1_3286
BBA: 
Bd1456
MXA: 
MXAN_1594 MXAN_3533 MXAN_7320
MFU: 
LILAB_00765 LILAB_09810 LILAB_25640
MSD: 
MYSTI_04440 MYSTI_07975
MYM: 
A176_003378 A176_005387 A176_007206
CCX: 
COCOR_04507(mhpA)
SUR: 
STAUR_0075
AGE: 
AA314_01736 AA314_07271
MLO: 
mll0858
MLN: 
A9174_34080
MAMO: 
A6B35_25120
MESO: 
BSQ44_02485
HOE: 
IMCC20628_01951
AAK: 
AA2016_6097 AA2016_6624
PLA: 
Plav_1541
SME: 
SMa1939
RHI: 
NGR_c25670
AVI: 
Avi_5443 Avi_7425
RET: 
RHE_CH02023
RLG: 
Rleg_5524
RLU: 
RLEG12_08535
BJA: 
bll0346 bll2329 blr5284(mhpA)
BJU: 
BJ6T_03060 BJ6T_44970
BJP: 
RN69_01475 RN69_21820
BRA: 
BRADO5116 BRADO6045 BRADO6299 BRADO6922 BRADO6969
BBT: 
BBta_0563 BBta_1323 BBta_5585
BRS: 
S23_04900 S23_29970
AOL: 
S58_05250 S58_25650 S58_62180 S58_64590
BRC: 
BCCGELA001_02420
BRAD: 
BF49_0499 BF49_6344
BIC: 
LMTR13_37190
RPA: 
RPA4675
RPB: 
RPB_0903
RPC: 
RPC_0888
RPD: 
RPD_1015
RPE: 
RPE_0909
RPT: 
Rpal_5156
RPX: 
Rpdx1_4852
NHA: 
Nham_0924
BOP: 
AXW83_08875
BVV: 
BHK69_29735
XAU: 
Xaut_0928 Xaut_1304
AZC: 
AZC_2882
MNO: 
Mnod_1196
MAQU: 
Maq22A_c21910(ubiH)
CHEL: 
AL346_18165
CDQ: 
BOQ54_10225
DEQ: 
XM25_13330
RHZ: 
RHPLAN_39020 RHPLAN_46430 RHPLAN_54800 RHPLAN_55040 RHPLAN_59560 RHPLAN_68900
MAAD: 
AZF01_22265
MMED: 
Mame_00145(mhpA)
PSIN: 
CAK95_00690 CAK95_01450 CAK95_10620 CAK95_11340 CAK95_19995
RBM: 
TEF_20555
CSE: 
Cseg_1743
CHQ: 
AQ619_16845
SIL: 
SPO0682
SIT: 
TM1040_2624
RMB: 
K529_012615
JAN: 
Jann_1432
RLI: 
RLO149_c034870
DSH: 
Dshi_3815
PSF: 
PSE_p0359
PGA: 
PGA1_c00410(mhpA)
PGL: 
PGA2_c30450(mhpA)
PGD: 
Gal_00174 Gal_04165
PHP: 
PhaeoP97_00271(mhpA)
OAR: 
OA238_c45820(mhpA)
LMD: 
METH_00430
RED: 
roselon_00793
MALG: 
MALG_01680
CON: 
TQ29_16145
RSU: 
NHU_04299
RHM: 
B5V46_17430
RHC: 
RGUI_2337
PPHR: 
APZ00_24030
LAP: 
ACP90_19245 ACP90_19785 ACP90_22385
LAGG: 
B0E33_02925 B0E33_03505 B0E33_05810
DAA: 
AKL17_3374
SUAM: 
BOO69_03345
TOM: 
BWR18_01940
THW: 
BMG03_05335 BMG03_15605
LVS: 
LOKVESSMR4R_00436(mhpA)
HBA: 
Hbal_2586
NAR: 
Saro_3413
NPP: 
PP1Y_AT10582 PP1Y_Mpl10234
NPN: 
JI59_22130
NRE: 
BES08_23655
SPHK: 
SKP52_13040
SPHP: 
LH20_19515
SWI: 
Swit_0776 Swit_1569 Swit_3526
STAX: 
MC45_16555
SKR: 
BRX40_00715 BRX40_06690
SJP: 
SJA_C2-01110
SCH: 
Sphch_0445
SPHB: 
EP837_03054
SPHR: 
BSY17_3122
BLAS: 
BSY18_2911
ELQ: 
Ga0102493_113019
RGI: 
RGI145_15235 RGI145_22240
MGY: 
MGMSRv2__1299
AZL: 
AZL_024700(mhpA)
ALI: 
AZOLI_2571
ATI: 
AL072_06585
AHU: 
A6A40_10210
PGV: 
SL003B_3055
APB: 
SAR116_0587 SAR116_1173
BCU: 
BCAH820_3038
BTW: 
BF38_4197
BACO: 
OXB_0850
GYC: 
GYMC61_2290 GYMC61_2311
GYA: 
GYMC52_1418 GYMC52_1439
GCT: 
GC56T3_2042 GC56T3_2063
GGH: 
GHH_c14760 GHH_c14970
GSR: 
GS3922_09215
GEJ: 
A0V43_04615 A0V43_04720
ANM: 
GFC28_3623
ANL: 
GFC29_1810
VIG: 
BKP57_15280
AAD: 
TC41_1825
SAY: 
TPY_3023(mhpA)
SAP: 
Sulac_0869
MPA: 
MAP_0694
MAO: 
MAP4_3170
MAVI: 
RC58_15710
MAVU: 
RE97_15740
MAV: 
MAV_0878 MAV_1804 MAV_2736
MAVD: 
NF84_03735
MAVR: 
LA63_03835
MAVA: 
LA64_03845
MIT: 
OCO_07340
MIA: 
OCU_07350
MIE: 
LG41_03640
MIR: 
OCQ_07490
MID: 
MIP_01270
MYO: 
OEM_07420
MCHI: 
AN480_04825
MSM: 
MSMEG_2485(mhpA) MSMEG_4866(mhpA)
MSG: 
MSMEI_4741
MSB: 
LJ00_24065
MSN: 
LI99_24070
MSH: 
LI98_24075
MSA: 
Mycsm_02399 Mycsm_04569
MVA: 
Mvan_0593 Mvan_4245 Mvan_4906
MGI: 
Mflv_2401
MSP: 
Mspyr1_18330
MAB: 
MAB_2573c
MABB: 
MASS_2521(mhpA2)
MMV: 
MYCMA_08595
MAY: 
LA62_13070
MABO: 
NF82_12855
MAZ: 
LA61_12965
MYS: 
NF92_11545
MYC: 
NF90_11540
MCHE: 
BB28_12825
MIZ: 
BAB75_13830
MMC: 
Mmcs_3786
MKM: 
Mkms_3859
MJL: 
Mjls_3790
MJD: 
JDM601_1131 JDM601_3458
MMI: 
MMAR_1503 MMAR_2987 MMAR_4777
MMAE: 
MMARE11_14030 MMARE11_29100 MMARE11_46060
MRH: 
MycrhN_3918 MycrhN_5737
MMM: 
W7S_03590(mhpA)
MCB: 
Mycch_3689
MLI: 
MULP_01621 MULP_02835 MULP_05007
MKN: 
MKAN_03140 MKAN_10220(mhpA) MKAN_22325
MKS: 
LG40_03160 LG40_10060 LG40_22110
MKI: 
LH54_03165 LH54_10205 LH54_22240
MNE: 
D174_02465
MYV: 
G155_20875 G155_29365
MYE: 
AB431_09625 AB431_09650 AB431_21460
MGO: 
AFA91_16185
MFT: 
XA26_21670 XA26_42580 XA26_59360
MPHL: 
MPHLCCUG_03811(mhpA)
MVQ: 
MYVA_4048(mhpA)
ASD: 
AS9A_0161(mhpA) AS9A_2775 AS9A_2861
CTER: 
A606_01150(mhpA)
CII: 
CIMIT_11785
NFR: 
ERS450000_00746(mhpA_1) ERS450000_01152(mhpA_2)
NBR: 
O3I_019040 O3I_022415
NNO: 
NONO_c37030 NONO_c50130
NSL: 
BOX37_17295 BOX37_19990
RHA: 
RHA1_ro01845 RHA1_ro03540
RER: 
RER_39300
REY: 
O5Y_18240
REB: 
XU06_18435 XU06_30310
ROP: 
ROP_15300 ROP_33340 ROP_70970
ROA: 
Pd630_LPD00132 Pd630_LPD06016 Pd630_LPD07937
REQ: 
REQ_30240 REQ_44410
RHB: 
NY08_3999 NY08_4323
RAV: 
AAT18_08960 AAT18_09330 AAT18_24150 AAT18_26405
RFA: 
A3L23_02166(mhpA)
TPR: 
Tpau_2814
SRT: 
Srot_1726
DTM: 
BJL86_2837
SCO: 
SCO5773(SC4H8.12c)
SMA: 
SAV_563(mhpA)
SGR: 
SGR_1740
SGB: 
WQO_26800
SCB: 
SCAB_15001(mhpA) SCAB_24921 SCAB_8371 SCAB_90671
SSX: 
SACTE_4942
SVL: 
Strvi_2104
SCT: 
SCAT_4549 SCAT_5484 SCAT_5493
SCY: 
SCATT_45380 SCATT_54820 SCATT_54910
SFA: 
Sfla_1578
SBH: 
SBI_01641 SBI_03335
SHY: 
SHJG_1239 SHJG_6862
SHO: 
SHJGH_1074 SHJGH_6622
SVE: 
SVEN_5428
SDV: 
BN159_1386 BN159_1743 BN159_2675 BN159_8213
SALB: 
XNR_1086 XNR_4437
SALS: 
SLNWT_1511
STRP: 
F750_5287
SFI: 
SFUL_5696
SCI: 
B446_27010
SRC: 
M271_00805 M271_05905 M271_15085 M271_39040
SALU: 
DC74_5863
SALL: 
SAZ_12610
SLV: 
SLIV_09750
SGU: 
SGLAU_24875
SVT: 
SVTN_27840 SVTN_37810
STRE: 
GZL_02980
SCW: 
TU94_24450
SLD: 
T261_0753 T261_2312
SXI: 
SXIM_45180
STRM: 
M444_36445 M444_36490
STRC: 
AA958_26575
SAMB: 
SAM23877_5477
SPRI: 
SPRI_2127
SCZ: 
ABE83_08580
SCX: 
AS200_04235 AS200_13170
SRW: 
TUE45_00110(mhpA_2) TUE45_06270(mhpA_3)
STRF: 
ASR50_26120 ASR50_31415
SLE: 
sle_19000(sle_19000)
SRN: 
A4G23_04290(mhpA)
SPAV: 
Spa2297_24420
STRT: 
A8713_23670
SCLF: 
BB341_05605
SGS: 
AVL59_09905 AVL59_10590
STSI: 
A4E84_24990 A4E84_29485
SLS: 
SLINC_6182
SNR: 
SNOUR_12895
SPLU: 
LK06_024980
STRD: 
NI25_10355
SNW: 
BBN63_08005
KSK: 
KSE_53620
MICR: 
BMW26_14550
CPHY: 
B5808_02225
ARL: 
AFL94_17525
ARZ: 
AUT26_01395 AUT26_19750 AUT26_19800
PSUL: 
AU252_22600
NAE: 
BHE16_09095
CFL: 
Cfla_0297
ARS: 
ADJ73_04155
KFL: 
Kfla_3146
AER: 
AERYTH_14530
NDA: 
Ndas_1867
NAL: 
B005_5046
TCU: 
Tcur_0725
NOA: 
BKM31_00565 BKM31_17415
FRA: 
Francci3_2111
FRE: 
Franean1_3055 Franean1_4747
FRI: 
FraEuI1c_5357
FAL: 
FRAAL2325 FRAAL2565 FRAAL3395
FSY: 
FsymDg_4214
NML: 
Namu_1344
GOB: 
Gobs_1919 Gobs_4947
BSD: 
BLASA_4817
MMAR: 
MODMU_2466 MODMU_5405
SEN: 
SACE_3057 SACE_3947 SACE_4082
AMD: 
AMED_5351(mhpA)
AMN: 
RAM_26760 RAM_27265(mhpA)
AMM: 
AMES_5286(mhpA)
AMZ: 
B737_5286(mhpA)
AMQ: 
AMETH_4196
PDX: 
Psed_4218
PSEE: 
FRP1_28405
PSEQ: 
AD006_07580
PECQ: 
AD017_15395
PHH: 
AFB00_05385
SESP: 
BN6_48960 BN6_78510
KAL: 
KALB_2278
KPHY: 
AOZ06_18895 AOZ06_28145
LED: 
BBK82_17995 BBK82_40645
ALL: 
CRK59933
MAU: 
Micau_3866
MIL: 
ML5_4551
VMA: 
VAB18032_18855
ASE: 
ACPL_5050(mhpA)
AFS: 
AFR_22975
CAI: 
Caci_6461
CWO: 
Cwoe_3896
HHB: 
Hhub_2446
HLR: 
HALLA_01830 HALLA_03495
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9098055
  Authors
Ferrandez A, Garcia JL, Diaz E.
  Title
Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12.
  Journal
J Bacteriol 179:2573-81 (1997)
DOI:10.1128/JB.179.8.2573-2581.1997
  Sequence
[eco:b0347]
LinkDB All DBs

KEGG   ENZYME: 1.14.13.127Help
Entry
EC 1.14.13.127              Enzyme                                 

Name
3-(3-hydroxyphenyl)propanoate hydroxylase;
mhpA (gene name)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
3-(3-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (2-hydroxylating)
Reaction(IUBMB)
(1) 3-(3-hydroxyphenyl)propanoate + NADH + H+ + O2 = 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD+ [RN:R06786];
(2) (2E)-3-(3-hydroxyphenyl)prop-2-enoate + NADH + H+ + O2 = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H2O + NAD+ [RN:R06787]
Reaction(KEGG)
Substrate
3-(3-hydroxyphenyl)propanoate [CPD:C11457];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007];
(2E)-3-(3-hydroxyphenyl)prop-2-enoate [CPD:C12621]
Product
3-(2,3-dihydroxyphenyl)propanoate [CPD:C04044];
H2O [CPD:C00001];
NAD+ [CPD:C00003];
(2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate [CPD:C12623]
Comment
A flavoprotein (FAD). This enzyme participates in a meta-cleavage pathway employed by the bacterium Escherichia coli for the degradation of various phenylpropanoid compounds.
History
EC 1.14.13.127 created 2011
Pathway
Phenylalanine metabolism
Microbial metabolism in diverse environments
Orthology
K05712  
3-(3-hydroxy-phenyl)propionate hydroxylase
Genes
ECO: 
b0347(mhpA)
ECJ: 
JW0338(mhpA)
ECD: 
ECOK: 
ECE: 
Z0445(mhpA)
ECS: 
ECs0402(mhpA)
ECF: 
ETW: 
ECSP_0411(mhpA)
ELX: 
EOJ: 
EOI: 
ECO111_0383(mhpA)
EOH: 
ECO103_0329(mhpA)
EOK: 
G2583_0460(mhpA)
ELR: 
ECO55CA74_02210(mhpA)
ECX: 
EcHS_A0411(mhpA)
ECW: 
EcE24377A_0371(mhpA)
ECM: 
EcSMS35_0378(mhpA)
ECY: 
ECSE_0372
ECR: 
ECIAI1_0348(mhpA)
ECQ: 
ECED1_0375(mhpA)
ECK: 
EC55989_0354(mhpA)
ECT: 
ECIAI39_0331(mhpA)
EOC: 
CE10_0315(mhpA)
EUM: 
ECUMN_0390(mhpA)
ELO: 
EC042_0384(mhpA)
ELH: 
ETEC_0403
ESE: 
ECSF_0318
ESO: 
O3O_05555(mhpA)
ESM: 
O3M_19725(mhpA)
ESL: 
O3K_19740(mhpA)
ECL: 
EcolC_3278
EBR: 
ECB_00301(mhpA)
EBD: 
ECBD_3310
EKO: 
EKO11_3495
EKF: 
KO11_21845(mhpA)
EDH: 
EcDH1_3259
EDJ: 
ECDH1ME8569_0334(mhpA)
ENA: 
ECNA114_0330(mhpA)
EUN: 
UMNK88_397
ELW: 
ECW_m0425(mhpA)
ELL: 
WFL_02090(mhpA)
ELP: 
P12B_c0307(mhpA) P12B_c0365(mhpA)
EBL: 
ECD_00301(mhpA)
EBE: 
B21_00305(mhpA)
ECOA: 
APECO78_05255
ECOL: 
LY180_02125(mhpA)
ECOJ: 
P423_01825(mhpA)
ECOO: 
ECRM13514_0499(mhpA)
ECOH: 
ECRM13516_0327(mhpA)
ECOS: 
EC958_0491
SSN: 
SSON_0297(mhpA)
SHQ: 
A0259_05405(mhpA)
KPN: 
KPN_02122(mhpA)
KPU: 
KP1_3217(mhpA)
KPM: 
KPHS_31050
KPP: 
A79E_2122
KPK: 
A593_25665(mhpA)
KPH: 
KPNIH24_12930(mhpA)
KPZ: 
KPNIH27_14865(mhpA)
KPV: 
KPNIH29_15525(mhpA)
KPW: 
KPNIH30_15805(mhpA)
KPY: 
KPNIH31_14660(mhpA)
KPG: 
KPNIH32_15700(mhpA)
KPC: 
KPNIH10_15325(mhpA)
KPQ: 
KPR0928_15300(mhpA)
KPT: 
VK055_0339(mhpA)
KPE: 
KPK_2201(mhpA)
KPO: 
KPN2242_13565(mhpA)
KPR: 
KPR_2667 KPR_2668
KPJ: 
N559_2167
KPI: 
D364_10875(mhpA)
KPA: 
KPNJ1_02340
KPS: 
KPNJ2_02300
KPX: 
PMK1_04486(mhpA)
KPB: 
FH42_06705(mhpA)
KPNE: 
KU54_010815(mhpA)
KPNU: 
LI86_10770(mhpA)
KVA: 
Kvar_2153
KVD: 
KR75_23585(mhpA)
KVQ: 
SP68_04240(mhpA)
KOX: 
KOX_22695(mhpA)
KOE: 
A225_3416
KOY: 
J415_14950(mhpA)
KOK: 
KONIH1_16730(mhpA)
KOC: 
AB185_19175(mhpA)
KOM: 
HR38_20990(mhpA)
KQU: 
AVR78_19690(mhpA)
CFD: 
CFNIH1_11830(mhpA)
CIF: 
AL515_06435(mhpA)
EBT: 
EBL_c20040(mhpA1)
ROR: 
RORB6_04275(mhpA)
PGE: 
LG71_09620(mhpA)
KGO: 
CEW81_11370(mhpA)
EBF: 
D782_1982
SLQ: 
M495_12025
PLU: 
plu1437
PAY: 
PAU_02254
LEZ: 
GLE_5300
VNA: 
PN96_06275(mhpA)
VEJ: 
VEJY3_06780(mhpA)
VFU: 
vfu_A01977
PCQ: 
PcP3B5_43040(mhpA_3)
PPW: 
PputW619_1979
PPUN: 
PP4_19460
PFV: 
Psefu_2046
PSYR: 
N018_13885
PFS: 
PFLU_3081 PFLU_4110
PFE: 
PSF113_2094 PSF113_2493 PSF113_3456
PFW: 
PF1751_v1c35480
PFF: 
PFLUOLIPICF718150
PPZ: 
H045_07775(mhpA)
PCG: 
AXG94_01855
PVR: 
PverR02_10450 PverR02_12315(mhpA) PverR02_20750
PSTT: 
CH92_04330
PBA: 
PSEBR_a2350 PSEBR_a3645
PBC: 
CD58_10880 CD58_17315
PPUU: 
PputUW4_02144(mhpA)
PSK: 
U771_16375 U771_21540
PSW: 
LK03_20495
PPSY: 
AOC04_16940(mhpA)
PFK: 
PFAS1_24645
AEI: 
AOY20_07915(mhpA)
OSG: 
BST96_04145 BST96_04525 BST96_17355
WOC: 
BA177_04230
HCS: 
FF32_04635
HAK: 
KO116_03916
HCO: 
LOKO_00974(pcpB) LOKO_00984(mhpA)
ADI: 
B5T_01229
APAC: 
S7S_05355
MARS: 
A8C75_10110
SEDS: 
AAY24_02880
RSO: 
RSp0702
RSL: 
RPSI07_mp0600
RSN: 
RSPO_m01032(ubiF)
RSM: 
CMR15_mp10673
RSE: 
F504_4517
RPI: 
Rpic_4529
RPF: 
Rpic12D_4661
RPJ: 
N234_23045 N234_29540 N234_30015 N234_30845 N234_34290
RMN: 
TK49_12795 TK49_17220
RIN: 
ACS15_1388 ACS15_4654
REU: 
Reut_A0270 Reut_B4218 Reut_B5321 Reut_B5808
REH: 
H16_B0971(h16_B0971) H16_B1546(h16_B1546) H16_B2557(h16_B2557)
CNC: 
CNE_2c15470(mhpA1) CNE_2c24670(mhpA2) CNE_BB1p14220(mhpA)
RME: 
Rmet_0339
CTI: 
RALTA_B1347 RALTA_B2288
CBW: 
RR42_m3020 RR42_s0346 RR42_s1475
CGD: 
CR3_3181(mhpA) CR3_4109(mhpA)
CCUP: 
BKK81_18745 BKK81_21915 BKK81_23890
BMA: 
BMA2059
BMV: 
BMASAVP1_A0853
BML: 
BMA10229_A2685
BMN: 
BMA10247_1924
BMAL: 
DM55_2396
BMAE: 
DM78_2627
BMAQ: 
DM76_2381
BMAI: 
DM57_847
BMAF: 
DM51_1717
BMAZ: 
BM44_1291
BMAB: 
BM45_853
BPS: 
BPSL2532 BPSL2742
BPM: 
BURPS1710b_3014(mtmOII) BURPS1710b_3231
BPL: 
BURPS1106A_3216
BPD: 
BURPS668_3177
BPR: 
GBP346_A3356
BPSE: 
BDL_2704
BPSM: 
BBQ_569
BPSU: 
BBN_697
BPSD: 
BBX_1102
BPZ: 
BP1026B_I0573
BPQ: 
BPC006_I3259
BPK: 
BBK_2190
BPSH: 
DR55_1776
BPSA: 
BBU_2821
BPSO: 
X996_1416
BUT: 
X994_3416 X994_5940
BTE: 
BTH_I1395
BTQ: 
BTQ_2538
BTJ: 
BTJ_3156
BTZ: 
BTL_1087
BTD: 
BTI_862
BTV: 
BTHA_1179
BTHE: 
BTN_301
BTHM: 
BTRA_1295
BTHA: 
DR62_467
BTHL: 
BG87_1284
BOK: 
DM82_1354 DM82_2409
BOC: 
BG90_2324 BG90_3340
BVI: 
Bcep1808_0754 Bcep1808_5388 Bcep1808_5589
BVE: 
AK36_3498(mhpA) AK36_5080 AK36_51
BUR: 
Bcep18194_A3910 Bcep18194_A4123 Bcep18194_A4483
BCN: 
Bcen_0334 Bcen_5086 Bcen_6487
BCH: 
Bcen2424_0161 Bcen2424_0817 Bcen2424_5774 Bcen2424_6722
BCM: 
Bcenmc03_0786 Bcenmc03_4404
BCJ: 
BCAL1339 BCAL2996 BCAL3187 BCAM0077
BCEN: 
DM39_4116 DM39_4971 DM39_628 DM39_6548 DM39_846
BCEW: 
DM40_1483 DM40_5004(mhpA) DM40_5334
BCEO: 
I35_0670 I35_0874 I35_1234(mhpA) I35_4084(mhpA)
BAM: 
Bamb_0698 Bamb_0875 Bamb_4304
BAC: 
BamMC406_0715
BMU: 
Bmul_2566 Bmul_5805
BMJ: 
BMULJ_00672(mhpA) BMULJ_05717
BMK: 
DM80_6252 DM80_868
BMUL: 
NP80_3429 NP80_5229 NP80_833
BCT: 
GEM_2509 GEM_2711
BCED: 
DM42_1012 DM42_370 DM42_5077 DM42_818
BCEP: 
APZ15_07725 APZ15_08755 APZ15_10450
BDL: 
AK34_2355
BPYR: 
ABD05_09705 ABD05_33420
BCON: 
NL30_10610 NL30_11700 NL30_35890
BUB: 
BW23_920
BDF: 
WI26_03590 WI26_04540 WI26_30210
BLAT: 
WK25_03795 WK25_17345 WK25_27500
BTEI: 
WS51_00135 WS51_14365 WS51_15300
BSEM: 
WJ12_03695 WJ12_04670 WJ12_19400 WJ12_20050 WJ12_26040
BPSL: 
WS57_02980 WS57_12795 WS57_21495 WS57_22605
BMEC: 
WJ16_03730 WJ16_04700 WJ16_18530
BSTG: 
WT74_03995
BGL: 
bglu_2g00750
BGU: 
KS03_3563
BUG: 
BC1001_3698 BC1001_4373 BC1001_4612
BGE: 
BC1002_3962 BC1002_4181 BC1002_4724 BC1002_5806 BC1002_5811 BC1002_6621
BGF: 
BC1003_4885
BGD: 
bgla_1g15130 bgla_2g09170
BYI: 
BYI23_B003840
BUK: 
MYA_0708 MYA_5006 MYA_5137
BUO: 
BRPE64_BCDS09430
BUE: 
BRPE67_BCDS06410
BUL: 
BW21_2674 BW21_957
BUQ: 
AC233_20465 AC233_26985
BUD: 
AQ610_04190 AQ610_12650
BXE: 
Bxe_A2727 Bxe_B0428 Bxe_B1226 Bxe_B2329 Bxe_C0990
BXB: 
DR64_410 DR64_4661(mhpA) DR64_5764 DR64_6541 DR64_7461
BPH: 
Bphy_3513 Bphy_4050 Bphy_4192 Bphy_4535
BPX: 
BUPH_00265 BUPH_01175 BUPH_02477 BUPH_02488
BPY: 
Bphyt_5380 Bphyt_7215
BFN: 
OI25_6133 OI25_6980
BCAI: 
K788_0000774 K788_0001102
PSPW: 
BJG93_23975
PPK: 
U875_05840 U875_20200 U875_21900
PPNO: 
DA70_11715 DA70_12890 DA70_14580 DA70_22915
PPNM: 
LV28_07795 LV28_16105 LV28_17810 LV28_19235
PRB: 
X636_03735 X636_12265 X636_13980 X636_15115
PPUL: 
RO07_10205 RO07_12005
PSPU: 
NA29_06040 NA29_07810 NA29_08025
PAPI: 
SG18_10635 SG18_12335 SG18_24440
PVE: 
UC34_01905 UC34_03855 UC34_22405
POX: 
MB84_06345 MB84_08310
PTX: 
ABW99_01685 ABW99_04580 ABW99_12955 ABW99_20645
PFG: 
AB870_09220 AB870_13125 AB870_14930
PNR: 
AT302_09960 AT302_12120
BPE: 
BP3131
BPC: 
BPTD_3093
BPER: 
BN118_2796
BPET: 
B1917_0691
BPEU: 
Q425_31090
BPA: 
BPP0811
BPAR: 
BN117_0841
BBR: 
BB0895
BBM: 
BN115_0864
BBH: 
BN112_2547
BBX: 
BBS798_0868
BPT: 
Bpet0304 Bpet4008
BAV: 
BAV0531 BAV3126
BHO: 
D560_0451 D560_1693
BHM: 
D558_0449 D558_0450 D558_1682
BHZ: 
ACR54_00736(mhpA_1) ACR54_04380(mhpA_2) ACR54_04635(mhpA_3)
BTRM: 
SAMEA390648701822(mhpA)
BBRO: 
BAU06_02065
AXY: 
AXYL_00831 AXYL_00862 AXYL_02650 AXYL_03052(mhpA) AXYL_05594
AXO: 
NH44784_012811 NH44784_028501 NH44784_029771
AXN: 
AX27061_0876 AX27061_5341 AX27061_5466
AXS: 
LH59_04350 LH59_24580 LH59_25190
AXX: 
ERS451415_00865(mhpA_1) ERS451415_05371(mhpA_2) ERS451415_05492(mhpA_3)
ADT: 
APT56_04615 APT56_24535
AIS: 
BUW96_03325 BUW96_05370 BUW96_16675 BUW96_21370
PUT: 
PT7_2127
AMIM: 
MIM_c24060
CDN: 
BN940_02586
AFA: 
UZ73_07715
RHY: 
RD110_22340 RD110_22775
POL: 
Bpro_3000 Bpro_3718 Bpro_4535
PNA: 
Pnap_0616
AAA: 
Acav_1712
ACK: 
C380_21505
ACID: 
CBP33_04160
VEI: 
Veis_3422 Veis_3440 Veis_4632
DAC: 
Daci_0579 Daci_4008
DEL: 
DelCs14_0524 DelCs14_2791
DTS: 
BI380_06055 BI380_24540
DHK: 
BO996_00370 BO996_18345
VAP: 
Vapar_0291 Vapar_4781 Vapar_5105
VPE: 
Varpa_0301 Varpa_5439 Varpa_5826
VPD: 
VAPA_1c03530 VAPA_1c49470 VAPA_1c52960 VAPA_2c06770 VAPA_2c10690
CTT: 
CtCNB1_2361 CtCNB1_4501
CTES: 
O987_15285 O987_26695
CKE: 
B5M06_13690
RTA: 
Rta_01740 Rta_31330
LIM: 
L103DPR2_02457(mhpA_1) L103DPR2_02630(mhpA_2)
LIH: 
L63ED372_01280(mhpA_1) L63ED372_02668(mhpA_2)
HYR: 
BSY239_1873 BSY239_500
HYB: 
Q5W_11565 Q5W_15790
HYL: 
LPB072_08090 LPB072_18410
CBAA: 
SRAA_1361
JAZ: 
YQ44_11050
JAL: 
BZG29_16540
HSE: 
Hsero_0543 Hsero_1553 Hsero_3945(mhpA)
HSZ: 
ACP92_02705 ACP92_07800 ACP92_19680
HHT: 
F506_11265
HRB: 
Hrubri_0531 Hrubri_1454
MASW: 
AM586_03095
LCH: 
Lcho_4300
TIN: 
Tint_2994
THI: 
THI_3545
RDP: 
RD2015_1541
PKT: 
AT984_13220
MIU: 
ABE85_00305
SHD: 
SUTH_02820(mhpA)
EBA: 
ebA3297
AZO: 
azo3681(mhpA)
AZA: 
AZKH_2696 AZKH_4363
AZI: 
AzCIB_1299 AzCIB_4301
TMZ: 
Tmz1t_0850
TCL: 
Tchl_0093 Tchl_1491
APP: 
CAP2UW1_3286
BBA: 
Bd1456
MXA: 
MXAN_1594 MXAN_3533 MXAN_7320
MFU: 
LILAB_00765 LILAB_09810 LILAB_25640
MSD: 
MYSTI_04440 MYSTI_07975
MYM: 
A176_003378 A176_005387 A176_007206
CCX: 
COCOR_04507(mhpA)
SUR: 
STAUR_0075
AGE: 
AA314_01736 AA314_07271
MLO: 
mll0858
MLN: 
A9174_34080
MAMO: 
A6B35_25120
MESO: 
BSQ44_02485
HOE: 
IMCC20628_01951
AAK: 
AA2016_6097 AA2016_6624
PLA: 
Plav_1541
SME: 
SMa1939
RHI: 
NGR_c25670
AVI: 
Avi_5443 Avi_7425
RET: 
RHE_CH02023
RLG: 
Rleg_5524
RLU: 
RLEG12_08535
BJA: 
bll0346 bll2329 blr5284(mhpA)
BJU: 
BJ6T_03060 BJ6T_44970
BJP: 
RN69_01475 RN69_21820
BRA: 
BRADO5116 BRADO6045 BRADO6299 BRADO6922 BRADO6969
BBT: 
BBta_0563 BBta_1323 BBta_5585
BRS: 
S23_04900 S23_29970
AOL: 
S58_05250 S58_25650 S58_62180 S58_64590
BRC: 
BCCGELA001_02420
BRAD: 
BF49_0499 BF49_6344
BIC: 
LMTR13_37190
RPA: 
RPA4675
RPB: 
RPB_0903
RPC: 
RPC_0888
RPD: 
RPD_1015
RPE: 
RPE_0909
RPT: 
Rpal_5156
RPX: 
Rpdx1_4852
NHA: 
Nham_0924
BOP: 
AXW83_08875
BVV: 
BHK69_29735
XAU: 
Xaut_0928 Xaut_1304
AZC: 
AZC_2882
MNO: 
Mnod_1196
MAQU: 
Maq22A_c21910(ubiH)
CHEL: 
AL346_18165
CDQ: 
BOQ54_10225
DEQ: 
XM25_13330
RHZ: 
RHPLAN_39020 RHPLAN_46430 RHPLAN_54800 RHPLAN_55040 RHPLAN_59560 RHPLAN_68900
MAAD: 
AZF01_22265
MMED: 
Mame_00145(mhpA)
PSIN: 
CAK95_00690 CAK95_01450 CAK95_10620 CAK95_11340 CAK95_19995
RBM: 
TEF_20555
CSE: 
Cseg_1743
CHQ: 
AQ619_16845
SIL: 
SPO0682
SIT: 
TM1040_2624
RMB: 
K529_012615
JAN: 
Jann_1432
RLI: 
RLO149_c034870
DSH: 
Dshi_3815
PSF: 
PSE_p0359
PGA: 
PGA1_c00410(mhpA)
PGL: 
PGA2_c30450(mhpA)
PGD: 
Gal_00174 Gal_04165
PHP: 
PhaeoP97_00271(mhpA)
OAR: 
OA238_c45820(mhpA)
LMD: 
METH_00430
RED: 
roselon_00793
MALG: 
MALG_01680
CON: 
TQ29_16145
RSU: 
NHU_04299
RHM: 
B5V46_17430
RHC: 
RGUI_2337
PPHR: 
APZ00_24030
LAP: 
ACP90_19245 ACP90_19785 ACP90_22385
LAGG: 
B0E33_02925 B0E33_03505 B0E33_05810
DAA: 
AKL17_3374
SUAM: 
BOO69_03345
TOM: 
BWR18_01940
THW: 
BMG03_05335 BMG03_15605
LVS: 
LOKVESSMR4R_00436(mhpA)
HBA: 
Hbal_2586
NAR: 
Saro_3413
NPP: 
PP1Y_AT10582 PP1Y_Mpl10234
NPN: 
JI59_22130
NRE: 
BES08_23655
SPHK: 
SKP52_13040
SPHP: 
LH20_19515
SWI: 
Swit_0776 Swit_1569 Swit_3526
STAX: 
MC45_16555
SKR: 
BRX40_00715 BRX40_06690
SJP: 
SJA_C2-01110
SCH: 
Sphch_0445
SPHB: 
EP837_03054
SPHR: 
BSY17_3122
BLAS: 
BSY18_2911
ELQ: 
Ga0102493_113019
RGI: 
RGI145_15235 RGI145_22240
MGY: 
MGMSRv2__1299
AZL: 
AZL_024700(mhpA)
ALI: 
AZOLI_2571
ATI: 
AL072_06585
AHU: 
A6A40_10210
PGV: 
SL003B_3055
APB: 
SAR116_0587 SAR116_1173
BCU: 
BCAH820_3038
BTW: 
BF38_4197
BACO: 
OXB_0850
GYC: 
GYMC61_2290 GYMC61_2311
GYA: 
GYMC52_1418 GYMC52_1439
GCT: 
GC56T3_2042 GC56T3_2063
GGH: 
GHH_c14760 GHH_c14970
GSR: 
GS3922_09215
GEJ: 
A0V43_04615 A0V43_04720
ANM: 
GFC28_3623
ANL: 
GFC29_1810
VIG: 
BKP57_15280
AAD: 
TC41_1825
SAY: 
TPY_3023(mhpA)
SAP: 
Sulac_0869
MPA: 
MAP_0694
MAO: 
MAP4_3170
MAVI: 
RC58_15710
MAVU: 
RE97_15740
MAV: 
MAV_0878 MAV_1804 MAV_2736
MAVD: 
NF84_03735
MAVR: 
LA63_03835
MAVA: 
LA64_03845
MIT: 
OCO_07340
MIA: 
OCU_07350
MIE: 
LG41_03640
MIR: 
OCQ_07490
MID: 
MIP_01270
MYO: 
OEM_07420
MCHI: 
AN480_04825
MSM: 
MSMEG_2485(mhpA) MSMEG_4866(mhpA)
MSG: 
MSMEI_4741
MSB: 
LJ00_24065
MSN: 
LI99_24070
MSH: 
LI98_24075
MSA: 
Mycsm_02399 Mycsm_04569
MVA: 
Mvan_0593 Mvan_4245 Mvan_4906
MGI: 
Mflv_2401
MSP: 
Mspyr1_18330
MAB: 
MAB_2573c
MABB: 
MASS_2521(mhpA2)
MMV: 
MYCMA_08595
MAY: 
LA62_13070
MABO: 
NF82_12855
MAZ: 
LA61_12965
MYS: 
NF92_11545
MYC: 
NF90_11540
MCHE: 
BB28_12825
MIZ: 
BAB75_13830
MMC: 
Mmcs_3786
MKM: 
Mkms_3859
MJL: 
Mjls_3790
MJD: 
JDM601_1131 JDM601_3458
MMI: 
MMAR_1503 MMAR_2987 MMAR_4777
MMAE: 
MMARE11_14030 MMARE11_29100 MMARE11_46060
MRH: 
MycrhN_3918 MycrhN_5737
MMM: 
W7S_03590(mhpA)
MCB: 
Mycch_3689
MLI: 
MULP_01621 MULP_02835 MULP_05007
MKN: 
MKAN_03140 MKAN_10220(mhpA) MKAN_22325
MKS: 
LG40_03160 LG40_10060 LG40_22110
MKI: 
LH54_03165 LH54_10205 LH54_22240
MNE: 
D174_02465
MYV: 
G155_20875 G155_29365
MYE: 
AB431_09625 AB431_09650 AB431_21460
MGO: 
AFA91_16185
MFT: 
XA26_21670 XA26_42580 XA26_59360
MPHL: 
MPHLCCUG_03811(mhpA)
MVQ: 
MYVA_4048(mhpA)
ASD: 
AS9A_0161(mhpA) AS9A_2775 AS9A_2861
CTER: 
A606_01150(mhpA)
CII: 
CIMIT_11785
NFR: 
ERS450000_00746(mhpA_1) ERS450000_01152(mhpA_2)
NBR: 
O3I_019040 O3I_022415
NNO: 
NONO_c37030 NONO_c50130
NSL: 
BOX37_17295 BOX37_19990
RHA: 
RHA1_ro01845 RHA1_ro03540
RER: 
RER_39300
REY: 
O5Y_18240
REB: 
XU06_18435 XU06_30310
ROP: 
ROP_15300 ROP_33340 ROP_70970
ROA: 
Pd630_LPD00132 Pd630_LPD06016 Pd630_LPD07937
REQ: 
REQ_30240 REQ_44410
RHB: 
NY08_3999 NY08_4323
RAV: 
AAT18_08960 AAT18_09330 AAT18_24150 AAT18_26405
RFA: 
A3L23_02166(mhpA)
TPR: 
Tpau_2814
SRT: 
Srot_1726
DTM: 
BJL86_2837
SCO: 
SCO5773(SC4H8.12c)
SMA: 
SAV_563(mhpA)
SGR: 
SGR_1740
SGB: 
WQO_26800
SCB: 
SCAB_15001(mhpA) SCAB_24921 SCAB_8371 SCAB_90671
SSX: 
SACTE_4942
SVL: 
Strvi_2104
SCT: 
SCAT_4549 SCAT_5484 SCAT_5493
SCY: 
SCATT_45380 SCATT_54820 SCATT_54910
SFA: 
Sfla_1578
SBH: 
SBI_01641 SBI_03335
SHY: 
SHJG_1239 SHJG_6862
SHO: 
SHJGH_1074 SHJGH_6622
SVE: 
SVEN_5428
SDV: 
BN159_1386 BN159_1743 BN159_2675 BN159_8213
SALB: 
XNR_1086 XNR_4437
SALS: 
SLNWT_1511
STRP: 
F750_5287
SFI: 
SFUL_5696
SCI: 
B446_27010
SRC: 
M271_00805 M271_05905 M271_15085 M271_39040
SALU: 
DC74_5863
SALL: 
SAZ_12610
SLV: 
SLIV_09750
SGU: 
SGLAU_24875
SVT: 
SVTN_27840 SVTN_37810
STRE: 
GZL_02980
SCW: 
TU94_24450
SLD: 
T261_0753 T261_2312
SXI: 
SXIM_45180
STRM: 
M444_36445 M444_36490
STRC: 
AA958_26575
SAMB: 
SAM23877_5477
SPRI: 
SPRI_2127
SCZ: 
ABE83_08580
SCX: 
AS200_04235 AS200_13170
SRW: 
TUE45_00110(mhpA_2) TUE45_06270(mhpA_3)
STRF: 
ASR50_26120 ASR50_31415
SLE: 
sle_19000(sle_19000)
SRN: 
A4G23_04290(mhpA)
SPAV: 
Spa2297_24420
STRT: 
A8713_23670
SCLF: 
BB341_05605
SGS: 
AVL59_09905 AVL59_10590
STSI: 
A4E84_24990 A4E84_29485
SLS: 
SLINC_6182
SNR: 
SNOUR_12895
SPLU: 
LK06_024980
STRD: 
NI25_10355
SNW: 
BBN63_08005
KSK: 
KSE_53620
MICR: 
BMW26_14550
CPHY: 
B5808_02225
ARL: 
AFL94_17525
ARZ: 
AUT26_01395 AUT26_19750 AUT26_19800
PSUL: 
AU252_22600
NAE: 
BHE16_09095
CFL: 
Cfla_0297
ARS: 
ADJ73_04155
KFL: 
Kfla_3146
AER: 
AERYTH_14530
NDA: 
Ndas_1867
NAL: 
B005_5046
TCU: 
Tcur_0725
NOA: 
BKM31_00565 BKM31_17415
FRA: 
Francci3_2111
FRE: 
Franean1_3055 Franean1_4747
FRI: 
FraEuI1c_5357
FAL: 
FRAAL2325 FRAAL2565 FRAAL3395
FSY: 
FsymDg_4214
NML: 
Namu_1344
GOB: 
Gobs_1919 Gobs_4947
BSD: 
BLASA_4817
MMAR: 
MODMU_2466 MODMU_5405
SEN: 
SACE_3057 SACE_3947 SACE_4082
AMD: 
AMED_5351(mhpA)
AMN: 
RAM_26760 RAM_27265(mhpA)
AMM: 
AMES_5286(mhpA)
AMZ: 
B737_5286(mhpA)
AMQ: 
AMETH_4196
PDX: 
Psed_4218
PSEE: 
FRP1_28405
PSEQ: 
AD006_07580
PECQ: 
AD017_15395
PHH: 
AFB00_05385
SESP: 
BN6_48960 BN6_78510
KAL: 
KALB_2278
KPHY: 
AOZ06_18895 AOZ06_28145
LED: 
BBK82_17995 BBK82_40645
ALL: 
CRK59933
MAU: 
Micau_3866
MIL: 
ML5_4551
VMA: 
VAB18032_18855
ASE: 
ACPL_5050(mhpA)
AFS: 
AFR_22975
CAI: 
Caci_6461
CWO: 
Cwoe_3896
HHB: 
Hhub_2446
HLR: 
HALLA_01830 HALLA_03495
 » show all
Taxonomy
Reference
1  [PMID:6345502]
  Authors
Burlingame R, Chapman PJ.
  Title
Catabolism of phenylpropionic acid and its 3-hydroxy derivative by Escherichia coli.
  Journal
J. Bacteriol. 155 (1983) 113-21.
Reference
2  [PMID:3531186]
  Authors
Burlingame RP, Wyman L, Chapman PJ
  Title
Isolation and characterization of Escherichia coli mutants defective for phenylpropionate degradation.
  Journal
J. Bacteriol. 168 (1986) 55-64.
Reference
3  [PMID:9098055]
  Authors
Ferrandez A, Garcia JL, Diaz E
  Title
Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12.
  Journal
J. Bacteriol. 179 (1997) 2573-81.
  Sequence
[eco:b0347]
Reference
4  [PMID:9603882]
  Authors
Diaz E, Ferrandez A, Garcia JL.
  Title
Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.
  Journal
J. Bacteriol. 180 (1998) 2915-23.
  Sequence
[eco:b0347]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
LinkDB All DBs

KEGG   REACTION: R06786Help
Entry
R06786                      Reaction                               

Name
3-(3-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (2-hydroxylating)
Definition
3-(3-Hydroxyphenyl)propanoic acid + Oxygen + NADH + H+ <=> 3-(2,3-Dihydroxyphenyl)propanoate + H2O + NAD+
Equation
Reaction class
C00003_C00004
C04044_C11457
Enzyme
Pathway
Phenylalanine metabolism
Microbial metabolism in diverse environments
Degradation of aromatic compounds
Orthology
K05712  
3-(3-hydroxy-phenyl)propionate hydroxylase [EC:1.14.13.127]
Other DBs
RHEA: 
LinkDB All DBs

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