KEGG   ORTHOLOGY: K09753Help
Entry
K09753                      KO                                     

Name
CCR
Definition
cinnamoyl-CoA reductase [EC:1.2.1.44]
Pathway
Phenylpropanoid biosynthesis
Module
M00039  
Monolignol biosynthesis, phenylalanine/tyrosine  => monolignol
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Biosynthesis of other secondary metabolites
   00940 Phenylpropanoid biosynthesis
    K09753  CCR; cinnamoyl-CoA reductase
KEGG modules [BR:ko00002]
 Pathway module
  Secondary metabolism
   Biosynthesis of secondary metabolites
    M00039  Monolignol biosynthesis, phenylalanine / tyrosine  => monolignol
     K09753  CCR; cinnamoyl-CoA reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.44  cinnamoyl-CoA reductase
     K09753  CCR; cinnamoyl-CoA reductase
BRITE hierarchy
Other DBs
Genes
RSS: 
ATH: 
AT1G15950(CCR1) AT1G80820(CCR2)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
18595421
GRA: 
105768894
GHI: 
107906426 107958455
EGR: 
104423225
GMX: 
100789070 100796771 100799994 100811528
PVU: 
PHAVU_005G182100g PHAVU_010G160700g
VRA: 
106762574 106773575
VAR: 
108320633 108334476
CCAJ: 
109812665 109812977
MTR: 
MTR_2g104960 MTR_4g006940
CAM: 
101489660 101497779
ADU: 
107459741 107463776
AIP: 
107617648 107618046
LJA: 
Lj0g3v0120879.1(Lj0g3v0120879.1) Lj3g3v0013390.1(Lj3g3v0013390.1) Lj3g3v2128240.1(Lj3g3v2128240.1) Lj3g3v2148260.1(Lj3g3v2148260.1)
LANG: 
109340430 109356075 109358362
FVE: 
101302179
PPER: 
18782836 18783603 18784457
PMUM: 
103328170 103328171 103328172 103328195
MDM: 
103424888 103438772
PXB: 
103945355 103945358 108867111
ZJU: 
107408651 107408760 107409091 107425908
CSV: 
101213412 101218838 101219069
CMO: 
103499837 103500289 103500290 103502823 103502824
RCU: 
8259741
JCU: 
105630319
POP: 
POPTR_0001s03660g POPTR_0001s03670g POPTR_0001s14890g POPTR_0001s14910g(POPTRDRAFT_814849) POPTR_0001s14940g(POPTRDRAFT_178801) POPTR_0001s14950g POPTR_0001s14970g POPTR_0001s14980g POPTR_0003s17980g(POPTRDRAFT_813757)
VVI: 
100251623
SLY: 
100125904(CCR1) 778359(CCR2)
SPEN: 
107012453 107023856
SOT: 
102577453 102580211
INI: 
109162983 109164697 109164749 109191772
SIND: 
105158313 105165128
BVG: 
104904880
NNU: 
104603320 104610717
OSA: 
4331085(OJ1112_G06.14) 4345689 4346438(OJ1352_A10.23) 4347074(CCR)
DOSA: 
Os01t0283600-00(Os01g0283600) Os01t0283700-01(Os01g0283700) Os02t0180700-01(Os02g0180700) Os02t0808800-01(Os02g0808800) Os02t0811400-00(Os02g0811400) Os02t0811600-00(Os02g0811600) Os02t0811800-01(Os02g0811800) Os02t0812000-01(Os02g0812000) Os08t0277200-01(Os08g0277200) Os08t0441500-01(Os08g0441500) Os09t0127300-01(Os09g0127300) Os09t0262000-00(Os09g0262000) Os09t0419200-01(Os09g0419200)
OBR: 
102711504 102711778 102712056 102714531 102714947 102715891 102716196 102716621 102721008 102722421
BDI: 
100822439 100823534 100823680 100831132 100831271 100832790 100840321
ATS: 
F775_07290 F775_10611 F775_11982 F775_11983 F775_15360 F775_16292 F775_18269 F775_19113 F775_19114 F775_19856 F775_30573 F775_30664 F775_32936
SBI: 
8063428 8077848
ZMA: 
100285564 100382657 103634692 103634693 103654125 109946031 542463(cncr1) 542735(cncr2)
SITA: 
101755442 101756000 101756805 101757221 101761894 101763396 101779528 101784783 101785020
PDA: 
103702969 103710428 103714248
EGU: 
105036005 105050729 105060184
MUS: 
103970696 103970996 103983923
ATR: 
18447024
SMO: 
SELMODRAFT_123171 SELMODRAFT_134883 SELMODRAFT_134989 SELMODRAFT_227659 SELMODRAFT_227661 SELMODRAFT_228517 SELMODRAFT_228519 SELMODRAFT_234633 SELMODRAFT_450549(CCR1-1) SELMODRAFT_450552(CCR1-2) SELMODRAFT_85242
PPP: 
PHYPADRAFT_111821 PHYPADRAFT_122374 PHYPADRAFT_143208 PHYPADRAFT_229491
FCY: 
FRACYDRAFT_268205
 » show all
TaxonomyKoalaUniProt
LinkDB All DBs

KEGG   ENZYME: 1.2.1.44Help
Entry
EC 1.2.1.44                 Enzyme                                 

Name
cinnamoyl-CoA reductase;
feruloyl-CoA reductase;
cinnamoyl-coenzyme A reductase;
ferulyl-CoA reductase;
feruloyl coenzyme A reductase;
p-hydroxycinnamoyl coenzyme A reductase;
cinnamoyl-CoA:NADPH reductase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)
Reaction(IUBMB)
cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+ [RN:R02506]
Reaction(KEGG)
Substrate
cinnamaldehyde [CPD:C00903];
CoA [CPD:C00010];
NADP+ [CPD:C00006]
Product
cinnamoyl-CoA [CPD:C00540];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Acts also on a number of substituted cinnamoyl esters of coenzyme A.
History
EC 1.2.1.44 created 1978
Pathway
Phenylpropanoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K09753  
cinnamoyl-CoA reductase
Genes
RSS: 
ATH: 
AT1G15950(CCR1) AT1G80820(CCR2)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
18595421
GRA: 
105768894
GHI: 
107906426 107958455
EGR: 
104423225
GMX: 
100789070 100796771 100799994 100811528
PVU: 
PHAVU_005G182100g PHAVU_010G160700g
VRA: 
106762574 106773575
VAR: 
108320633 108334476
CCAJ: 
109812665 109812977
MTR: 
MTR_2g104960 MTR_4g006940
CAM: 
101489660 101497779
ADU: 
107459741 107463776
AIP: 
107617648 107618046
LJA: 
Lj0g3v0120879.1(Lj0g3v0120879.1) Lj3g3v0013390.1(Lj3g3v0013390.1) Lj3g3v2128240.1(Lj3g3v2128240.1) Lj3g3v2148260.1(Lj3g3v2148260.1)
LANG: 
109340430 109356075 109358362
FVE: 
101302179
PPER: 
18782836 18783603 18784457
PMUM: 
103328170 103328171 103328172 103328195
MDM: 
103424888 103438772
PXB: 
103945355 103945358 108867111
ZJU: 
107408651 107408760 107409091 107425908
CSV: 
101213412 101218838 101219069
CMO: 
103499837 103500289 103500290 103502823 103502824
RCU: 
8259741
JCU: 
105630319
POP: 
POPTR_0001s03660g POPTR_0001s03670g POPTR_0001s14890g POPTR_0001s14910g(POPTRDRAFT_814849) POPTR_0001s14940g(POPTRDRAFT_178801) POPTR_0001s14950g POPTR_0001s14970g POPTR_0001s14980g POPTR_0003s17980g(POPTRDRAFT_813757)
VVI: 
100251623
SLY: 
100125904(CCR1) 778359(CCR2)
SPEN: 
107012453 107023856
SOT: 
102577453 102580211
INI: 
109162983 109164697 109164749 109191772
SIND: 
105158313 105165128
BVG: 
104904880
NNU: 
104603320 104610717
OSA: 
4331085(OJ1112_G06.14) 4345689 4346438(OJ1352_A10.23) 4347074(CCR)
DOSA: 
Os01t0283600-00(Os01g0283600) Os01t0283700-01(Os01g0283700) Os02t0180700-01(Os02g0180700) Os02t0808800-01(Os02g0808800) Os02t0811400-00(Os02g0811400) Os02t0811600-00(Os02g0811600) Os02t0811800-01(Os02g0811800) Os02t0812000-01(Os02g0812000) Os08t0277200-01(Os08g0277200) Os08t0441500-01(Os08g0441500) Os09t0127300-01(Os09g0127300) Os09t0262000-00(Os09g0262000) Os09t0419200-01(Os09g0419200)
OBR: 
102711504 102711778 102712056 102714531 102714947 102715891 102716196 102716621 102721008 102722421
BDI: 
100822439 100823534 100823680 100831132 100831271 100832790 100840321
ATS: 
F775_07290 F775_10611 F775_11982 F775_11983 F775_15360 F775_16292 F775_18269 F775_19113 F775_19114 F775_19856 F775_30573 F775_30664 F775_32936
SBI: 
8063428 8077848
ZMA: 
100285564 100382657 103634692 103634693 103654125 109946031 542463(cncr1) 542735(cncr2)
SITA: 
101755442 101756000 101756805 101757221 101761894 101763396 101779528 101784783 101785020
PDA: 
103702969 103710428 103714248
EGU: 
105036005 105050729 105060184
MUS: 
103970696 103970996 103983923
ATR: 
18447024
SMO: 
SELMODRAFT_123171 SELMODRAFT_134883 SELMODRAFT_134989 SELMODRAFT_227659 SELMODRAFT_227661 SELMODRAFT_228517 SELMODRAFT_228519 SELMODRAFT_234633 SELMODRAFT_450549(CCR1-1) SELMODRAFT_450552(CCR1-2) SELMODRAFT_85242
PPP: 
PHYPADRAFT_111821 PHYPADRAFT_122374 PHYPADRAFT_143208 PHYPADRAFT_229491
FCY: 
FRACYDRAFT_268205
 » show all
Taxonomy
Reference
1  [PMID:236926]
  Authors
Gross GG, Kreiten W.
  Title
Reduction of coenzyme A thioesters of cinnamic acids with an enzyme preparation from lignifying tissue of Forsythia.
  Journal
FEBS. Lett. 54 (1975) 259-62.
Reference
2  [PMID:6365550]
  Authors
Sarni F, Grand C, Boudet AM.
  Title
Purification and properties of cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogenase from poplar stems (Populus X euramericana).
  Journal
Eur. J. Biochem. 139 (1984) 259-65.
Reference
3  [PMID:7454]
  Authors
Wengenmayer H, Ebel J, Grisebach H.
  Title
Enzymic synthesis of lignin precursors. Purification and properties of a cinnamoyl-CoA: NADPH reductase from cell suspension cultures of soybean (Glycinemax).
  Journal
Eur. J. Biochem. 65 (1976) 529-36.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
59929-39-4
LinkDB All DBs

KEGG   REACTION: R02506Help
Entry
R02506                      Reaction                               

Name
cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)
Definition
Cinnamaldehyde + CoA + NADP+ <=> Cinnamoyl-CoA + NADPH + H+
Equation
Reaction class
C00005_C00006
C00010_C00540
C00540_C00903
Enzyme
Pathway
Phenylpropanoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K09753  
cinnamoyl-CoA reductase [EC:1.2.1.44]
LinkDB All DBs

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