KEGG   ORTHOLOGY: K10217Help
Entry
K10217                      KO                                     

Name
dmpC, xylG, praB
Definition
aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase [EC:1.2.1.32 1.2.1.85]
Pathway
Benzoate degradation
Tryptophan metabolism
Xylene degradation
Degradation of aromatic compounds
Module
M00038  
Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
M00569  
Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Overview
   01220 Degradation of aromatic compounds
    K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
  Amino acid metabolism
   00380 Tryptophan metabolism
    K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
  Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
   00622 Xylene degradation
    K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
KEGG modules [BR:ko00002]
 Pathway module
  Nucleotide and amino acid metabolism
   Aromatic amino acid metabolism
    M00038  Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
     K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
  Secondary metabolism
   Aromatics degradation
    M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
     K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.32  aminomuconate-semialdehyde dehydrogenase
     K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
    1.2.1.85  2-hydroxymuconate-6-semialdehyde dehydrogenase
     K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
BRITE hierarchy
Other DBs
Genes
PGE: 
SLQ: 
PSD: 
LAB: 
LA76x_2548(aldH8A1)
LAQ: 
LCP: 
LC55x_2794(aldH8A1)
LGU: 
LG3211_2666(aldh8a1)
LEZ: 
LEM: 
RHD: 
DJI: 
CH75_03340
DJA: 
HY57_09330
DKO: 
I596_481
LRZ: 
BJI69_00885
PPSE: 
BN5_3621(xylG)
PCQ: 
PcP3B5_23470(amnC)
PPW: 
PputW619_2012
PPJ: 
RK21_04239
PVR: 
PverR02_14685
PSC: 
A458_06530
PSTU: 
UIB01_22730
PBM: 
CL52_14700
PKC: 
PKB_3261(amnc1) PKB_3609(amnc3)
PALK: 
PSAKL28_05930
PSOS: 
POS17_2264
PFK: 
PFAS1_28785
AVN: 
Avin_08730(xylG) Avin_30620(lapC)
AVL: 
AvCA_08730(xylG) AvCA_30620(lapC)
AVD: 
AvCA6_08730(xylG) AvCA6_30620(lapC)
ACX: 
Achr_32710(xylG)
SWD: 
Swoo_1410
COZ: 
A3Q34_02635
COLW: 
A3Q33_02670
MAD: 
HP15_1111(betB) HP15_4032(betB)
MSR: 
AU15_09320 AU15_21090 AU15_22065 AU15_22425
MLQ: 
ASQ50_09225
MSQ: 
BKP64_13860
LAL: 
AT746_01255
CYQ: 
Q91_0507(xylG) Q91_1784(lapC)
CZA: 
CYCME_0670 CYCME_2104
BLEP: 
AL038_01305
WMA: 
WM2015_1463
HCS: 
FF32_08345
APAC: 
S7S_06985
KKO: 
Kkor_0387
KGE: 
TQ33_1983
KSD: 
KS2013_2033
GBI: 
PG2T_02235
TBN: 
TBH_C0927
AQL: 
BXU06_16865
RSO: 
RSp0890(dmpC)
RSM: 
CMR15_mp10874
RSE: 
F504_4327
RPI: 
Rpic_4622
RPF: 
Rpic12D_3546
RPJ: 
N234_08145(gabD) N234_12220
RIN: 
ACS15_4686
REU: 
Reut_B5498 Reut_B5689
REH: 
H16_B0547(h16_B0547)
CNC: 
CNE_2c04930(dmpC) CNE_BB1p12000(dmpC1) CNE_BB1p13290(dmpC2)
RME: 
Rmet_1322(dmpC) Rmet_5206(amnC)
CBW: 
RR42_m1056 RR42_s2485
CCUP: 
BKK81_23305 BKK81_27085
BVI: 
Bcep1808_7602
BUR: 
Bcep18194_B2962 Bcep18194_C7647
BCJ: 
BCAM2132(nbaE)
BCEN: 
DM39_4835
BCEO: 
I35_6014(nbaE)
BMUL: 
NP80_3862
BCT: 
GEM_5404
BCED: 
DM42_4994
BCON: 
NL30_24605
BDF: 
WI26_15980
BTEI: 
WS51_00555
BPSL: 
WS57_12170
BUG: 
BC1001_3834
BUQ: 
AC233_11200
BXE: 
Bxe_A1147(amnC)
BXB: 
DR64_3306
BRH: 
RBRH_03003
BPX: 
BUPH_00408
BPY: 
Bphyt_1465
BFN: 
OI25_258
PPK: 
U875_01905 U875_06935 U875_20575
PPNO: 
DA70_13265 DA70_24010
PPNM: 
LV28_06695 LV28_17435
PRB: 
X636_02635 X636_07565 X636_13600
PPUL: 
RO07_00735 RO07_11540
PSPU: 
NA29_07455 NA29_10890
PAPI: 
SG18_00950 SG18_11865
PVE: 
UC34_03315 UC34_17030
POX: 
MB84_07750 MB84_21810
PFG: 
AB870_04075 AB870_14465
PNR: 
AT302_11495 AT302_15075
BAV: 
BAV0552(amnC)
BHZ: 
ACR54_00824(amnC_1)
AXY: 
AXYL_02527 AXYL_05539
AXO: 
NH44784_030391
AXN: 
AX27061_5279
AXS: 
LH59_24315
AXX: 
ERS451415_05308(amnC)
ADT: 
APT56_24280
AIS: 
BUW96_02880 BUW96_16325
PUT: 
PT7_3613
CDN: 
BN940_01146 BN940_04321
POL: 
Bpro_5132
AJS: 
Ajs_0220
ACID: 
CBP33_01090
VEI: 
Veis_2787
VPD: 
VAPA_1c22810
CTT: 
CtCNB1_3151
ADN: 
Alide_0335
ADK: 
Alide2_0280
HYL: 
LPB072_18170
MPT: 
Mpe_A2275
JAG: 
GJA_237
LCH: 
Lcho_3354
RBU: 
PG1C_09710
DAR: 
Daro_2775 Daro_3787 Daro_3806
AZO: 
azo1852(lapC) azo2435(nahI)
TMZ: 
Tmz1t_3092
THU: 
AC731_001805
ARC: 
ABLL_2445
BBAC: 
EP01_17230
MXA: 
MXAN_0921
MFU: 
LILAB_04105
MSD: 
MYSTI_00939
MYM: 
A176_006058
CCX: 
COCOR_00871(amnC)
SUR: 
STAUR_2723
AGE: 
AA314_01332
ARA: 
Arad_7263(betB)
MSL: 
Msil_1476
CHEL: 
AL346_10040
MAAD: 
AZF01_08290
NAR: 
Saro_3855
NPP: 
PP1Y_AT15685 PP1Y_AT31595
NPN: 
JI59_24625
SMAG: 
AN936_00735
SMAZ: 
LH19_00745
STER: 
AOA14_03900
SGI: 
SGRAN_3552(amnC)
SWI: 
Swit_3519
SJP: 
SJA_C1-11860(hpaE_xylG)
SYB: 
TZ53_09005 TZ53_23450
SINB: 
SIDU_08335
ERY: 
CP97_14215
CNA: 
AB433_18135
TMO: 
TMO_b0431(dmpC)
MAGQ: 
MGMAQ_0648
BLI: 
BL03906
BLD: 
BLi03994(dmpC)
BLH: 
BaLi_c40080
BCA: 
BCE_2154
BCX: 
BCA_2152
BCF: 
bcf_10200
BCER: 
BCK_24235
BCEF: 
BcrFT9_01687
BTL: 
BALH_1841
BMYC: 
DJ92_4635
BPF: 
BpOF4_12595
BMQ: 
BMQ_3590
BMD: 
BMD_3575
BMEG: 
BG04_464
BACI: 
B1NLA3E_08450 B1NLA3E_09290
GST: 
HW35_13035
BACO: 
OXB_2507
BSM: 
BSM4216_0945
BSJ: 
UP17_10510
BGY: 
BGLY_4398
BHK: 
B4U37_13950
GTN: 
GTNG_3154(nbaE)
GYC: 
GYMC61_2295
GYA: 
GYMC52_1423
GCT: 
GC56T3_2058
GMC: 
GY4MC1_1599
GGH: 
GHH_c14810(dmpC)
GJF: 
M493_17930
GTH: 
Geoth_1682
PTL: 
AOT13_14425
LGY: 
T479_19630
VIG: 
BKP57_09395
LAO: 
AOX59_17235
FPN: 
ABE65_004725
FAR: 
ABE41_004870
BBE: 
BBR47_29750(dhaS)
PNP: 
IJ22_00660
ANX: 
ACH33_11720
AAC: 
Aaci_1622
AAD: 
TC41_1518(hpaE)
BTS: 
Btus_0966
TMR: 
Tmar_1783
SAY: 
TPY_0646(hpaE)
SAP: 
Sulac_2993
LPIL: 
LIP_2170
MIT: 
OCO_14810
MIA: 
OCU_15250
MJL: 
Mjls_4206
MGO: 
AFA91_00050
NFA: 
NFA_30520
NFR: 
ERS450000_01013(xylG)
NNO: 
NONO_c62070
RHA: 
RHA1_ro03868
RER: 
RER_04700 RER_59330
REY: 
O5Y_02260
REB: 
XU06_02460
ROP: 
ROP_37370 ROP_54040
REQ: 
REQ_05040(amnC)
RPY: 
Y013_12510
RAV: 
AAT18_08160
GBR: 
Gbro_0237
GTA: 
BCM27_21885
SCB: 
SCAB_15221(amnC)
SSX: 
SACTE_4117
SBH: 
SBI_01538
STRT: 
A8713_24460
MVD: 
AWU67_16670
AGY: 
ATC03_02600
ARZ: 
AUT26_08855
ICA: 
Intca_1091
JTE: 
ASJ30_00120
KFL: 
Kfla_5493
TCU: 
Tcur_0539
SRO: 
Sros_9116
NOA: 
BKM31_47335
FRI: 
FraEuI1c_1246
ALU: 
BB31_29195
PDX: 
Psed_2510
ALL: 
CRK56596
STP: 
Strop_3528
SAQ: 
Sare_3903
MAU: 
Micau_4941
MIL: 
ML5_3354
VMA: 
VAB18032_17800 VAB18032_28761
RRS: 
RoseRS_2577
RCA: 
Rcas_2406
CAU: 
Caur_1356
CAG: 
Cagg_2038
CHL: 
Chy400_1478
TTJ: 
TTHB240
TTL: 
TtJL18_2422
TSC: 
TSC_c11600
THC: 
TCCBUS3UF1_13030
TOS: 
Theos_2470
TBC: 
A0O31_00089
GES: 
VT84_03880(amnC)
ABA: 
Acid345_0685
CTM: 
Cabther_A0029
FLI: 
Fleli_4022
HSW: 
Hsw_0099
HYM: 
N008_07450
HYD: 
PK28_02600
HYE: 
AM218_13535
HYG: 
AUC43_04980
PKO: 
PKOR_07060
RUF: 
TH63_16330
RTI: 
DC20_06920
RUD: 
TH61_07810
MTT: 
Ftrac_2830
CAT: 
CA2559_07430
KDI: 
Krodi_1916
DOK: 
MED134_12911
DDO: 
I597_1376(amnC)
LAN: 
Lacal_1456
LVN: 
BWR22_13175
ASL: 
Aeqsu_0473
NDO: 
DDD_2048
NOM: 
AAT17_09460
NSD: 
BST91_09375
POM: 
MED152_12769
POB: 
LPB03_06875
PRN: 
BW723_00735
POLA: 
BXQ17_06205
WIN: 
WPG_2044
WIJ: 
BWZ20_05975
TEN: 
LPB136_00565
FOR: 
FORMB_05920
FOH: 
FORMA_06690
FTE: 
Fluta_1400
OHO: 
Oweho_2603
BBAU: 
AEM51_05930
AG: 
AAA26053(xylG)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7868591
  Authors
Inoue J, Shaw JP, Rekik M, Harayama S
  Title
Overlapping substrate specificities of benzaldehyde dehydrogenase (the xylC gene  product) and 2-hydroxymuconic semialdehyde dehydrogenase (the xylG gene product)  encoded by TOL plasmid pWW0 of Pseudomonas putida.
  Journal
J Bacteriol 177:1196-201 (1995)
DOI:10.1128/JB.177.5.1196-1201.1995
  Sequence
Reference
  Authors
Kasai D, Fujinami T, Abe T, Mase K, Katayama Y, Fukuda M, Masai E
  Title
Uncovering the protocatechuate 2,3-cleavage pathway genes.
  Journal
J Bacteriol 191:6758-68 (2009)
DOI:10.1128/JB.00840-09
  Sequence
LinkDB All DBs

KEGG   ENZYME: 1.2.1.85Help
Entry
EC 1.2.1.85                 Enzyme                                 

Name
2-hydroxymuconate-6-semialdehyde dehydrogenase;
xylG (gene name);
praB (gene name)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
2-hydroxymuconate-6-semialdehyde:NAD+ oxidoreductase
Reaction(IUBMB)
2-hydroxymuconate-6-semialdehyde + NAD+ + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NADH + 2 H+ [RN:R02762]
Reaction(KEGG)
R02762;
(other) R05353
Show
Substrate
2-hydroxymuconate-6-semialdehyde [CPD:C00682];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
(2Z,4E)-2-hydroxyhexa-2,4-dienedioate;
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
This substrate for this enzyme is formed by meta ring cleavage of catechol (EC 1.13.11.2, catechol 2,3-dioxygenase), and is an intermediate in the bacterial degradation of several aromatic compounds. Has lower activity with benzaldehyde [1]. Activity with NAD+ is more than 10-fold higher than with NADP+ [3]. cf. EC 1.2.1.32, aminomuconate-semialdehyde dehydrogenase.
History
EC 1.2.1.85 created 2012
Pathway
Benzoate degradation
Xylene degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K10217  
aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
Genes
PGE: 
SLQ: 
PSD: 
LAB: 
LA76x_2548(aldH8A1)
LAQ: 
LCP: 
LC55x_2794(aldH8A1)
LGU: 
LG3211_2666(aldh8a1)
LEZ: 
LEM: 
RHD: 
DJI: 
CH75_03340
DJA: 
HY57_09330
DKO: 
I596_481
LRZ: 
BJI69_00885
PPSE: 
BN5_3621(xylG)
PCQ: 
PcP3B5_23470(amnC)
PPW: 
PputW619_2012
PPJ: 
RK21_04239
PVR: 
PverR02_14685
PSC: 
A458_06530
PSTU: 
UIB01_22730
PBM: 
CL52_14700
PKC: 
PKB_3261(amnc1) PKB_3609(amnc3)
PALK: 
PSAKL28_05930
PSOS: 
POS17_2264
PFK: 
PFAS1_28785
AVN: 
Avin_08730(xylG) Avin_30620(lapC)
AVL: 
AvCA_08730(xylG) AvCA_30620(lapC)
AVD: 
AvCA6_08730(xylG) AvCA6_30620(lapC)
ACX: 
Achr_32710(xylG)
SWD: 
Swoo_1410
COZ: 
A3Q34_02635
COLW: 
A3Q33_02670
MAD: 
HP15_1111(betB) HP15_4032(betB)
MSR: 
AU15_09320 AU15_21090 AU15_22065 AU15_22425
MLQ: 
ASQ50_09225
MSQ: 
BKP64_13860
LAL: 
AT746_01255
CYQ: 
Q91_0507(xylG) Q91_1784(lapC)
CZA: 
CYCME_0670 CYCME_2104
BLEP: 
AL038_01305
WMA: 
WM2015_1463
HCS: 
FF32_08345
APAC: 
S7S_06985
KKO: 
Kkor_0387
KGE: 
TQ33_1983
KSD: 
KS2013_2033
GBI: 
PG2T_02235
TBN: 
TBH_C0927
AQL: 
BXU06_16865
RSO: 
RSp0890(dmpC)
RSM: 
CMR15_mp10874
RSE: 
F504_4327
RPI: 
Rpic_4622
RPF: 
Rpic12D_3546
RPJ: 
N234_08145(gabD) N234_12220
RIN: 
ACS15_4686
REU: 
Reut_B5498 Reut_B5689
REH: 
H16_B0547(h16_B0547)
CNC: 
CNE_2c04930(dmpC) CNE_BB1p12000(dmpC1) CNE_BB1p13290(dmpC2)
RME: 
Rmet_1322(dmpC) Rmet_5206(amnC)
CBW: 
RR42_m1056 RR42_s2485
CCUP: 
BKK81_23305 BKK81_27085
BVI: 
Bcep1808_7602
BUR: 
Bcep18194_B2962 Bcep18194_C7647
BCJ: 
BCAM2132(nbaE)
BCEN: 
DM39_4835
BCEO: 
I35_6014(nbaE)
BMUL: 
NP80_3862
BCT: 
GEM_5404
BCED: 
DM42_4994
BCON: 
NL30_24605
BDF: 
WI26_15980
BTEI: 
WS51_00555
BPSL: 
WS57_12170
BUG: 
BC1001_3834
BUQ: 
AC233_11200
BXE: 
Bxe_A1147(amnC)
BXB: 
DR64_3306
BRH: 
RBRH_03003
BPX: 
BUPH_00408
BPY: 
Bphyt_1465
BFN: 
OI25_258
PPK: 
U875_01905 U875_06935 U875_20575
PPNO: 
DA70_13265 DA70_24010
PPNM: 
LV28_06695 LV28_17435
PRB: 
X636_02635 X636_07565 X636_13600
PPUL: 
RO07_00735 RO07_11540
PSPU: 
NA29_07455 NA29_10890
PAPI: 
SG18_00950 SG18_11865
PVE: 
UC34_03315 UC34_17030
POX: 
MB84_07750 MB84_21810
PFG: 
AB870_04075 AB870_14465
PNR: 
AT302_11495 AT302_15075
BAV: 
BAV0552(amnC)
BHZ: 
ACR54_00824(amnC_1)
AXY: 
AXYL_02527 AXYL_05539
AXO: 
NH44784_030391
AXN: 
AX27061_5279
AXS: 
LH59_24315
AXX: 
ERS451415_05308(amnC)
ADT: 
APT56_24280
AIS: 
BUW96_02880 BUW96_16325
PUT: 
PT7_3613
CDN: 
BN940_01146 BN940_04321
POL: 
Bpro_5132
AJS: 
Ajs_0220
ACID: 
CBP33_01090
VEI: 
Veis_2787
VPD: 
VAPA_1c22810
CTT: 
CtCNB1_3151
ADN: 
Alide_0335
ADK: 
Alide2_0280
HYL: 
LPB072_18170
MPT: 
Mpe_A2275
JAG: 
GJA_237
LCH: 
Lcho_3354
RBU: 
PG1C_09710
DAR: 
Daro_2775 Daro_3787 Daro_3806
AZO: 
azo1852(lapC) azo2435(nahI)
TMZ: 
Tmz1t_3092
THU: 
AC731_001805
ARC: 
ABLL_2445
BBAC: 
EP01_17230
MXA: 
MXAN_0921
MFU: 
LILAB_04105
MSD: 
MYSTI_00939
MYM: 
A176_006058
CCX: 
COCOR_00871(amnC)
SUR: 
STAUR_2723
AGE: 
AA314_01332
ARA: 
Arad_7263(betB)
MSL: 
Msil_1476
CHEL: 
AL346_10040
MAAD: 
AZF01_08290
NAR: 
Saro_3855
NPP: 
PP1Y_AT15685 PP1Y_AT31595
NPN: 
JI59_24625
SMAG: 
AN936_00735
SMAZ: 
LH19_00745
STER: 
AOA14_03900
SGI: 
SGRAN_3552(amnC)
SWI: 
Swit_3519
SJP: 
SJA_C1-11860(hpaE_xylG)
SYB: 
TZ53_09005 TZ53_23450
SINB: 
SIDU_08335
ERY: 
CP97_14215
CNA: 
AB433_18135
TMO: 
TMO_b0431(dmpC)
MAGQ: 
MGMAQ_0648
BLI: 
BL03906
BLD: 
BLi03994(dmpC)
BLH: 
BaLi_c40080
BCA: 
BCE_2154
BCX: 
BCA_2152
BCF: 
bcf_10200
BCER: 
BCK_24235
BCEF: 
BcrFT9_01687
BTL: 
BALH_1841
BMYC: 
DJ92_4635
BPF: 
BpOF4_12595
BMQ: 
BMQ_3590
BMD: 
BMD_3575
BMEG: 
BG04_464
BACI: 
B1NLA3E_08450 B1NLA3E_09290
GST: 
HW35_13035
BACO: 
OXB_2507
BSM: 
BSM4216_0945
BSJ: 
UP17_10510
BGY: 
BGLY_4398
BHK: 
B4U37_13950
GTN: 
GTNG_3154(nbaE)
GYC: 
GYMC61_2295
GYA: 
GYMC52_1423
GCT: 
GC56T3_2058
GMC: 
GY4MC1_1599
GGH: 
GHH_c14810(dmpC)
GJF: 
M493_17930
GTH: 
Geoth_1682
PTL: 
AOT13_14425
LGY: 
T479_19630
VIG: 
BKP57_09395
LAO: 
AOX59_17235
FPN: 
ABE65_004725
FAR: 
ABE41_004870
BBE: 
BBR47_29750(dhaS)
PNP: 
IJ22_00660
ANX: 
ACH33_11720
AAC: 
Aaci_1622
AAD: 
TC41_1518(hpaE)
BTS: 
Btus_0966
TMR: 
Tmar_1783
SAY: 
TPY_0646(hpaE)
SAP: 
Sulac_2993
LPIL: 
LIP_2170
MIT: 
OCO_14810
MIA: 
OCU_15250
MJL: 
Mjls_4206
MGO: 
AFA91_00050
NFA: 
NFA_30520
NFR: 
ERS450000_01013(xylG)
NNO: 
NONO_c62070
RHA: 
RHA1_ro03868
RER: 
RER_04700 RER_59330
REY: 
O5Y_02260
REB: 
XU06_02460
ROP: 
ROP_37370 ROP_54040
REQ: 
REQ_05040(amnC)
RPY: 
Y013_12510
RAV: 
AAT18_08160
GBR: 
Gbro_0237
GTA: 
BCM27_21885
SCB: 
SCAB_15221(amnC)
SSX: 
SACTE_4117
SBH: 
SBI_01538
STRT: 
A8713_24460
MVD: 
AWU67_16670
AGY: 
ATC03_02600
ARZ: 
AUT26_08855
ICA: 
Intca_1091
JTE: 
ASJ30_00120
KFL: 
Kfla_5493
TCU: 
Tcur_0539
SRO: 
Sros_9116
NOA: 
BKM31_47335
FRI: 
FraEuI1c_1246
ALU: 
BB31_29195
PDX: 
Psed_2510
ALL: 
CRK56596
STP: 
Strop_3528
SAQ: 
Sare_3903
MAU: 
Micau_4941
MIL: 
ML5_3354
VMA: 
VAB18032_17800 VAB18032_28761
RRS: 
RoseRS_2577
RCA: 
Rcas_2406
CAU: 
Caur_1356
CAG: 
Cagg_2038
CHL: 
Chy400_1478
TTJ: 
TTHB240
TTL: 
TtJL18_2422
TSC: 
TSC_c11600
THC: 
TCCBUS3UF1_13030
TOS: 
Theos_2470
TBC: 
A0O31_00089
GES: 
VT84_03880(amnC)
ABA: 
Acid345_0685
CTM: 
Cabther_A0029
FLI: 
Fleli_4022
HSW: 
Hsw_0099
HYM: 
N008_07450
HYD: 
PK28_02600
HYE: 
AM218_13535
HYG: 
AUC43_04980
PKO: 
PKOR_07060
RUF: 
TH63_16330
RTI: 
DC20_06920
RUD: 
TH61_07810
MTT: 
Ftrac_2830
CAT: 
CA2559_07430
KDI: 
Krodi_1916
DOK: 
MED134_12911
DDO: 
I597_1376(amnC)
LAN: 
Lacal_1456
LVN: 
BWR22_13175
ASL: 
Aeqsu_0473
NDO: 
DDD_2048
NOM: 
AAT17_09460
NSD: 
BST91_09375
POM: 
MED152_12769
POB: 
LPB03_06875
PRN: 
BW723_00735
POLA: 
BXQ17_06205
WIN: 
WPG_2044
WIJ: 
BWZ20_05975
TEN: 
LPB136_00565
FOR: 
FORMB_05920
FOH: 
FORMA_06690
FTE: 
Fluta_1400
OHO: 
Oweho_2603
BBAU: 
AEM51_05930
 » show all
Taxonomy
Reference
1  [PMID:7868591]
  Authors
Inoue J, Shaw JP, Rekik M, Harayama S
  Title
Overlapping substrate specificities of benzaldehyde dehydrogenase (the xylC gene  product) and 2-hydroxymuconic semialdehyde dehydrogenase (the xylG gene product)  encoded by TOL plasmid pWW0 of Pseudomonas putida.
  Journal
J. Bacteriol. 177 (1995) 1196-201.
  Sequence
Reference
2  [PMID:17090920]
  Authors
Orii C, Takenaka S, Murakami S, Aoki K
  Title
Metabolism of 4-amino-3-hydroxybenzoic acid by Bordetella sp. strain 10d: A different modified meta-cleavage pathway for 2-aminophenols.
  Journal
Biosci. Biotechnol. Biochem. 70 (2006) 2653-61.
Reference
3  [PMID:19717587]
  Authors
Kasai D, Fujinami T, Abe T, Mase K, Katayama Y, Fukuda M, Masai E
  Title
Uncovering the protocatechuate 2,3-cleavage pathway genes.
  Journal
J. Bacteriol. 191 (2009) 6758-68.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
LinkDB All DBs

KEGG   REACTION: R02762Help
Entry
R02762                      Reaction                               

Name
2-hydroxymuconate semialdehyde:NAD+ 6-oxidoreductase
Definition
2-Hydroxymuconate semialdehyde + NAD+ + H2O <=> 2-Hydroxymuconate + NADH + H+
Equation
Reaction class
C00003_C00004
C00682_C02501
Enzyme
Pathway
Benzoate degradation
Metabolic pathways
Microbial metabolism in diverse environments
Degradation of aromatic compounds
Module
M00569  
Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Orthology
K10217  
aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase [EC:1.2.1.32 1.2.1.85]
Other DBs
RHEA: 
LinkDB All DBs

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