KEGG   ORTHOLOGY: K10621Help
Entry
K10621                      KO                                     

Name
cmtC, dhbA
Definition
2,3-dihydroxy-p-cumate/2,3-dihydroxybenzoate 3,4-dioxygenase [EC:1.13.11.- 1.13.11.14]
Pathway
Benzoate degradation
Xylene degradation
Degradation of aromatic compounds
Module
M00539  
Cumate degradation, p-cumate => 2-oxopent-4-enoate + 2-methylpropanoate
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Overview
   01220 Degradation of aromatic compounds
    K10621  cmtC, dhbA; 2,3-dihydroxy-p-cumate/2,3-dihydroxybenzoate 3,4-dioxygenase
  Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K10621  cmtC, dhbA; 2,3-dihydroxy-p-cumate/2,3-dihydroxybenzoate 3,4-dioxygenase
   00622 Xylene degradation
    K10621  cmtC, dhbA; 2,3-dihydroxy-p-cumate/2,3-dihydroxybenzoate 3,4-dioxygenase
KEGG modules [BR:ko00002]
 Pathway module
  Secondary metabolism
   Aromatics degradation
    M00539  Cumate degradation, p-cumate => 2-oxopent-4-enoate + 2-methylpropanoate
     K10621  cmtC, dhbA; 2,3-dihydroxy-p-cumate/2,3-dihydroxybenzoate 3,4-dioxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.14  2,3-dihydroxybenzoate 3,4-dioxygenase
     K10621  cmtC, dhbA; 2,3-dihydroxy-p-cumate/2,3-dihydroxybenzoate 3,4-dioxygenase
    1.13.11.-  
     K10621  cmtC, dhbA; 2,3-dihydroxy-p-cumate/2,3-dihydroxybenzoate 3,4-dioxygenase
BRITE hierarchy
Other DBs
Genes
PPSE: 
PPF: 
PPX: 
PMON: 
PMOT: 
SPOI: 
ZAL: 
CYQ: 
CZA: 
APAC: 
GBI: 
PG2T_01300 PG2T_14355
RSO: 
RSp0888(cmtC)
RSM: 
CMR15_mp10872
RSE: 
F504_4329(cmtC)
RPJ: 
N234_12230
CNC: 
CNE_BB1p12030 CNE_BB1p13310
BXE: 
Bxe_A3554
BXB: 
DR64_1253
BCAI: 
K788_0001492
PPK: 
U875_20520
PPNO: 
DA70_13210
PPNM: 
LV28_17490
PRB: 
X636_13655
PPUL: 
RO07_11595
PSPU: 
NA29_07510
PAPI: 
SG18_11920
PVE: 
UC34_03370
POX: 
MB84_07825
PFG: 
AB870_14520
PNR: 
AT302_11550
AXY: 
AXYL_02525
AIS: 
BUW96_02870
VPD: 
VAPA_1c22790(cmtC)
JAG: 
GJA_239
THU: 
AC731_007265
ARA: 
Arad_7267 Arad_7268
CHEL: 
AL346_10025 AL346_10030
RHZ: 
RHPLAN_03120 RHPLAN_03130
NRE: 
BES08_18560
SMAZ: 
LH19_27430
SWI: 
Swit_1756
TMO: 
TMO_b0428 TMO_b0429(bphC)
BACI: 
B1NLA3E_13985
PNP: 
IJ22_32360
MIT: 
OCO_14770
MIA: 
OCU_15210
MJL: 
Mjls_4210
SBH: 
SBI_01530
PSEQ: 
AD006_28375
PECQ: 
AD017_28765
AG: 
AFN52421(dhbA)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8631713
  Authors
Eaton RW.
  Title
p-Cumate catabolic pathway in Pseudomonas putida Fl: cloning and characterization of DNA carrying the cmt operon.
  Journal
J Bacteriol 178:1351-62 (1996)
DOI:10.1128/JB.178.5.1351-1362.1996
  Sequence
[ppf:Pput_2896]
Reference
  Authors
Marin M, Plumeier I, Pieper DH
  Title
Degradation of 2,3-dihydroxybenzoate by a novel meta-cleavage pathway.
  Journal
J Bacteriol 194:3851-60 (2012)
DOI:10.1128/JB.00430-12
  Sequence
LinkDB All DBs

KEGG   ENZYME: 1.13.11.14Help
Entry
EC 1.13.11.14               Enzyme                                 

Name
2,3-dihydroxybenzoate 3,4-dioxygenase;
o-pyrocatechuate oxygenase;
2,3-dihydroxybenzoate 1,2-dioxygenase;
2,3-dihydroxybenzoic oxygenase;
2,3-dihydroxybenzoate oxygenase;
2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing)
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (ring-opening)
Reaction(IUBMB)
2,3-dihydroxybenzoate + O2 = 3-carboxy-2-hydroxymuconate semialdehyde [RN:R01507]
Reaction(KEGG)
Substrate
2,3-dihydroxybenzoate [CPD:C00196];
O2 [CPD:C00007]
Product
3-carboxy-2-hydroxymuconate semialdehyde [CPD:C04480]
History
EC 1.13.11.14 created 1972, modified 1976
Pathway
Benzoate degradation
Microbial metabolism in diverse environments
Orthology
K10621  
2,3-dihydroxy-p-cumate/2,3-dihydroxybenzoate 3,4-dioxygenase
Genes
PPSE: 
PPF: 
PPX: 
PMON: 
PMOT: 
SPOI: 
ZAL: 
CYQ: 
CZA: 
APAC: 
GBI: 
PG2T_01300 PG2T_14355
RSO: 
RSp0888(cmtC)
RSM: 
CMR15_mp10872
RSE: 
F504_4329(cmtC)
RPJ: 
N234_12230
CNC: 
CNE_BB1p12030 CNE_BB1p13310
BXE: 
Bxe_A3554
BXB: 
DR64_1253
BCAI: 
K788_0001492
PPK: 
U875_20520
PPNO: 
DA70_13210
PPNM: 
LV28_17490
PRB: 
X636_13655
PPUL: 
RO07_11595
PSPU: 
NA29_07510
PAPI: 
SG18_11920
PVE: 
UC34_03370
POX: 
MB84_07825
PFG: 
AB870_14520
PNR: 
AT302_11550
AXY: 
AXYL_02525
AIS: 
BUW96_02870
VPD: 
VAPA_1c22790(cmtC)
JAG: 
GJA_239
THU: 
AC731_007265
ARA: 
Arad_7267 Arad_7268
CHEL: 
AL346_10025 AL346_10030
RHZ: 
RHPLAN_03120 RHPLAN_03130
NRE: 
BES08_18560
SMAZ: 
LH19_27430
SWI: 
Swit_1756
TMO: 
TMO_b0428 TMO_b0429(bphC)
BACI: 
B1NLA3E_13985
PNP: 
IJ22_32360
MIT: 
OCO_14770
MIA: 
OCU_15210
MJL: 
Mjls_4210
SBH: 
SBI_01530
PSEQ: 
AD006_28375
PECQ: 
AD017_28765
 » show all
Taxonomy
Reference
1
  Authors
Ribbons, D.W.
  Title
Bacterial oxidation of 2,3-dihydroxybenzoic acid - a new oxygenase.
  Journal
Biochem. J. 99 (1966) 30.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9032-31-9
LinkDB All DBs

KEGG   REACTION: R01507Help
Entry
R01507                      Reaction                               

Name
2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing)
Definition
2,3-Dihydroxybenzoate + Oxygen <=> 3-Carboxy-2-hydroxymuconate semialdehyde
Equation
Reaction class
C00196_C04480
Enzyme
Pathway
Benzoate degradation
Microbial metabolism in diverse environments
Orthology
K10621  
2,3-dihydroxy-p-cumate/2,3-dihydroxybenzoate 3,4-dioxygenase [EC:1.13.11.- 1.13.11.14]
Other DBs
RHEA: 
LinkDB All DBs

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