KEGG   ORTHOLOGY: K13231Help
Entry
K13231                      KO                                     

Name
STS
Definition
pinosylvin synthase [EC:2.3.1.146]
Pathway
Stilbenoid, diarylheptanoid and gingerol biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Biosynthesis of other secondary metabolites
   00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
    K13231  STS; pinosylvin synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.146  pinosylvin synthase
     K13231  STS; pinosylvin synthase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Type III PKS
   Plant type
    K13231  STS; pinosylvin synthase
BRITE hierarchy
Other DBs
RN: 
GO: 
Genes
AG: 
CAA87012(STS1) CAA87013(STS2)
TaxonomyKoalaUniProt
Reference
PMID:7698342
  Authors
Raiber S, Schroder G, Schroder J
  Title
Molecular and enzymatic characterization of two stilbene synthases from Eastern white pine (Pinus strobus). A single Arg/His difference determines the activity and the pH dependence of the enzymes.
  Journal
FEBS Lett 361:299-302 (1995)
DOI:10.1016/0014-5793(95)00199-J
  Sequence
LinkDB All DBs

KEGG   ENZYME: 2.3.1.146Help
Entry
EC 2.3.1.146                Enzyme                                 

Name
pinosylvin synthase;
stilbene synthase (ambiguous);
pine stilbene synthase (ambiguous)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing)
Reaction(IUBMB)
3 malonyl-CoA + cinnamoyl-CoA = 4 CoA + pinosylvin + 4 CO2 [RN:R02505]
Reaction(KEGG)
Substrate
malonyl-CoA [CPD:C00083];
cinnamoyl-CoA [CPD:C00540]
Product
CoA [CPD:C00010];
pinosylvin [CPD:C01745];
CO2 [CPD:C00011]
Comment
Not identical with EC 2.3.1.74 (naringenin-chalcone synthase) or EC 2.3.1.95 (trihydroxystilbene synthase).
History
EC 2.3.1.146 created 1992
Pathway
Stilbenoid, diarylheptanoid and gingerol biosynthesis
Biosynthesis of secondary metabolites
Orthology
K13231  
pinosylvin synthase
Reference
1
  Authors
Gehlert, R., Schoppner, A. and Kindl, H.
  Title
Stilbene synthase from seedlings of Pinus sylvestris - purification and induction in response to fungal infection.
  Journal
Mol. Plant-Microbe Interaction 3 (1990) 444-449.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
72994-49-1
LinkDB All DBs

KEGG   REACTION: R02505Help
Entry
R02505                      Reaction                               

Name
Malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing)
Definition
3 Malonyl-CoA + Cinnamoyl-CoA <=> 4 CoA + Pinosylvin + 4 CO2
Equation
3 C00083 + C00540 <=> 4 C00010 + C01745 + 4 C00011
Comment
multi-step reaction
Reaction class
C00010_C00083  C00010_C00540
C00540_C01745
Enzyme
Pathway
Stilbenoid, diarylheptanoid and gingerol biosynthesis
Biosynthesis of secondary metabolites
Orthology
K13231  
pinosylvin synthase [EC:2.3.1.146]
LinkDB All DBs

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