KEGG   ORTHOLOGY: K16269Help
Entry
K16269            Tight     KO                                     

Name
todD, tcbB
Definition
cis-1,2-dihydrobenzene-1,2-diol dehydrogenase [EC:1.3.1.19 1.3.1.-]
Pathway
Chlorocyclohexane and chlorobenzene degradation
Benzoate degradation
Toluene degradation
Polycyclic aromatic hydrocarbon degradation
Styrene degradation
Degradation of aromatic compounds
Module
M00547  
Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Overview
   01220 Degradation of aromatic compounds
    K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
  Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
   00361 Chlorocyclohexane and chlorobenzene degradation
    K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
   00623 Toluene degradation
    K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
   00643 Styrene degradation
    K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
   00624 Polycyclic aromatic hydrocarbon degradation
    K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
KEGG modules [BR:ko00002]
 Pathway module
  Secondary metabolism
   Aromatics degradation
    M00547  Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol
     K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.19  cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
     K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
    1.3.1.-  
     K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
BRITE hierarchy
Other DBs
Genes
PPF: 
PPX: 
T1E_4270(tobD)
PMON: 
PMOT: 
BPT: 
Bpet3742(hcaB)
AG: 
AAC43636(tcbB)
TaxonomyKoalaUniProt
Reference
PMID:2670929
  Authors
Zylstra GJ, Gibson DT
  Title
Toluene degradation by Pseudomonas putida F1. Nucleotide sequence of the todC1C2BADE genes and their expression in Escherichia coli.
  Journal
J Biol Chem 264:14940-6 (1989)
Reference
PMID:8626733
  Authors
Werlen C, Kohler HP, van der Meer JR
  Title
The broad substrate chlorobenzene dioxygenase and cis-chlorobenzene dihydrodiol dehydrogenase of Pseudomonas sp. strain P51 are linked evolutionarily to the enzymes for benzene and toluene degradation.
  Journal
J Biol Chem 271:4009-16 (1996)
DOI:10.1074/jbc.271.8.4009
  Sequence
LinkDB All DBs

KEGG   REACTION: R05397Help
Entry
R05397                      Reaction                               

Definition
3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 3,6-Dichlorocatechol + NADH + H+
Equation
Comment
cis-chlorobenzene dihydrodiol dehydrogenase, TcbB
Reaction class
C00003_C00004
C07093_C07094
Enzyme
1.3.1.-
Pathway
Chlorocyclohexane and chlorobenzene degradation
Metabolic pathways
Microbial metabolism in diverse environments
Degradation of aromatic compounds
Orthology
K16269  
cis-1,2-dihydrobenzene-1,2-diol dehydrogenase [EC:1.3.1.19 1.3.1.-]
LinkDB All DBs

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