Acinonyx jubatus (cheetah): 106989132
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Entry
106989132 CDS
T04657
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
aju
Acinonyx jubatus (cheetah)
Pathway
aju04120
Ubiquitin mediated proteolysis
aju04144
Endocytosis
aju04330
Notch signaling pathway
aju04668
TNF signaling pathway
aju04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
aju00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
106989132
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
106989132
04668 TNF signaling pathway
106989132
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
106989132
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
106989132
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
aju04131
]
106989132
04121 Ubiquitin system [BR:
aju04121
]
106989132
Enzymes [BR:
aju01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
106989132
Membrane trafficking [BR:
aju04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
106989132
Ubiquitin system [BR:
aju04121
]
Ubiquitin ligases (E3)
HECT type E3
106989132
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
106989132
NCBI-ProteinID:
XP_014943085
UniProt:
A0A6J0A8L3
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Position
A3:complement(24051806..24195753)
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AA seq
862 aa
AA seq
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MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVVTL
QLIGDKEPTETMGDLSVCLDGLQLESEVVTNGETTCSESASQNDDGSRPKDEARTNPNGS
DEPEDSGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNTVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcgcagcttggttcaatgggtagcctgaccatgaaatcacagctt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagttgatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttattgtcacccctgtgagtaaattgcat
tttcgcgtgtggagtcatcagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgacttta
cagcttataggtgacaaagagccaacagagacaatgggagacttgtcagtttgtcttgat
gggctgcagttagagtctgaagttgttaccaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctctagaccgaaggatgaagcaagaacaaatccaaatggatca
gatgaacctgaggattcaggggctggtgaaaataggaaggtcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatctgctacttctgaaagtgat
ggatccagtacaggctctctgccaccaacaaatataaattcaaatacatctgaaggagca
acatctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
actgtacctcaagctcccctaccacctggttgggagcagagagtggaccagcatgggcga
gtttactacgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccgacattggaatctgtccggaactatgaacagtggcaa
ctccaacgtagtcagcttcaaggagcaatgcagcaatttaaccagagattcatttatggg
aatcaggatttgtttactacatcgcaaaataaagaatttgatccccttggtcccctgcct
cctggatgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaggaccccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtagatggaattccatattttgtggaccacaataga
agaacaaccacctatattgatccccgcactggaaaatctgctctagacaatggaccacag
atagcctacgtacgggacttcaaggcaaaggttcagtatttccggttctggtgtcagcaa
ctggcaatgccacagcacataaagattacagtgacaagaaaaacattgtttgaagattcc
tttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtca
cacgaggtgttgaaccccatgtattgcctgtttgaatatgcaggaaaggataactactgc
ctgcagattaatcctgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgccatggctttgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatattgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cctaatggtggcaatattcttgtgacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctgcagtttgttactggaacttgtcgattgccagttggagga
tttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaactggttacccagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtga
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