Amborella trichopoda: 18433925 Help Entry 18433925          CDS       T02990                                  Name (RefSeq) auxin transport protein BIG   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism atr  Amborella trichopoda Brite KEGG Orthology (KO) [BR:atr00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:atr04121]     18433925 Enzymes [BR:atr01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      18433925 Ubiquitin system [BR:atr04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     18433925 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UbLigase_R4 ZZ zf-UBR TFIID-18kDa Motif Other DBs NCBI-GeneID:  18433925 NCBI-ProteinID:  XP_020522820 LinkDB All DBs Position Unknown AA seq 5108 aa AA seqDB search MAEIKKLLDLLTEENAMVDLSQRLRSDNAKLGLSELASIIEQSIKENDDGKLVFQIWNES QIESLLSVLSYVVYTTRSLTVEAAESALVRVFESSVEFCIYYVEKCGLNGDHGADLQKTV IHLLEIALLDKVDTDLDSVKLDSPAVLMDCLPVIPANSSRVKQDRYMKCTLRGINCSVKA EPVDTAMLALASEYLPANRQVSLSTEDVPHQDWNSMISLSQHWAVVHGKCIPRLINICKE LLKPSQLSDEHNGDSHFQSIVILSKRILSLVARLTREAPYVASDVELLLQAAALAELLPE LFKHRHDPLNFDSCAEEKRIEHHLMVLMEDFFHFVEAVFHSDNIFLNIKTCISASMLNIL DTQVWSYDKHSSIQKPPLVFAPQVIMYLLKLIGEVRTQTCQVLSWKQKSDINSVENFMNS EIGVAPSFNISSEKVSLVERYTSEQLLRLIFPIGGHWLDDLIHLASFLHSQGVKYKVKND RLRQVRAKSPAPSDKDPAVSHEDDALFGDLFCEPGRQGGMTDTRDQPPVASDMINIGTNI PLQGAIELLTFLKSSIFSPEWDSSVCKEACVMLHERHISILLSMLQFQVCLFDEGIPNSA VSACQKQLGHVSDVSFDLLYSLLARRALSRCLEEHLASQILKVEKGHFVYNDYTLVLLAH AMISRVGLSGRLFRIKVFEAYIDFILEKANDVCSNCPSLGDTFAGLPSLFHFEILLMAFH SSSVSEKVSFAKRVFDALQAVSHTPAEFSCTLLTAWSLLVSRLILILRHMIYYPSTFPSW LLSHIRTKLREVPSRGSSSGIVNDRLLSWVSTTIQSIMAVWVKDRPVLGNLLPLLIDVVP VPNSASLDGQVLQDLGLNQDDVHDAFSQILGLWKGKKAEAVEDLVLERYCFLLCWDTLSC IRSPSVRVDTWSLDLGRMDSFIQFSHFLVSKADVTSYIGSGNFTEVVTSVLQQLSITHEP FQVKERTWDFLRDGAWLSLILSLLQVGIGRFSEKDALQGLESCWVEDIHGGNYFLSIAES VVVALFQNNQVGSVIEWLSVLLHRYLHALQEAFVMALDRQECEVGLFSSSLLLIQSGCEQ CPEAELLEKIGASPALLEYLYGLGSKLNELVEREDLENLSRAFRRSLLHGFPSHLQTNSG ALLSCIVSVEGIICTFESLIKVKDSTGAIHIDDDVLLRLLDSVMMVKLGRIFEHIHGKLD VIYSYFFPSEKGNLDHSVLFLLKHMENFLKEVVSREKINLGVLEVLIKNTVDLVDRIRKD PAKVDSLKCYLGINNDKNKEAKKLYPIQNGNLLVLLDVLDTCHTEAVSMKILQLFNDLLS GELCCSLKVEAQKKFLGMDLACLSKWLEKKLLGCMIETSGGVSTAKGSPVALRELTLNVI ICLVSPSSEINSKELRLHFVEAMLMSLEDAFMQFDIHTAKAYFNSIFQLCNGDSSMRHLV EKTVRLMDKFLCDERFLEGLKFLFGFLWSILSACGANKGTGDKFSGKHWSSSSSGAASTI PRTVGSVSSQGSETLVLPSSQESGSATVDCDATSVDEDEDDGTSDGELASVDKDDDDDSN NERALASKVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCARVCHRGHRVVYSRSSRF FCDCGAGGVRGSSCQCLKPRKYTPSNSAPVRATNNFQPFLSFSEDGELPPDSDSDFDEDG LADIESSFKLSIPKEEQEGLARLLMNVDVESLLIQLCSRLLPAVTGRRECNLSKDQKVVL GDDRILSYNTDLLQLKKAYKSGSLDMKIKAEYSNARELKTHLVNGSLIKSLLSVSRRGRL AAGEGDKVAIFDVGQLIGQPSVAPITADKTNVKPLSKNIVRFEIVHILFNPLVENYLAVA GYEECQVLTVNHRGEVTDRLAVELASQGAYIRRIDWVPGSQVQLMGITNTFVKIYDLSQD NISPMHYFTLDDDLIVDATLVTAPQGKIFLLVLSELGRLFRLELSMGGDVGAKQMTDIIE LDKAPHSRGLSLYFSSTFRFLFLSYQDGTTLIGRLDANAKTLTEISAIYGDEQDGKLRPA GLHHWKEMLDGSGFFVCFSSLKLNSILAVSIGVHELLAQNLRHTGGSSSLSLVGIAAYRP LSKDRTHCLVLYDDGSLQIYSANSLGSNSGSNLTSDHAKKLGSGILSSRVCSGSNPEFPL DFFEKTVCISPDVKLGGDAIRNGDSESAKQNLVSDDGYLESPSASGFKIIVFNSNPDIAM VGFRIHVGNTSASHIPSEITIFQRVIKLDEGMRSWYDIPFTTAEALLADEEFTISVGPTF NGSTLPRIDSLEVYGRLKDDFGWKEKMDAVLDMEAHVLGATSGVSGHGKKYRPLQAVSLQ EQVIADGLKLLSAYYSLFRSQACAEIEDAKIESCKLKCKKLLETIFENDREIMLQCAACH VLQTLFPKKEMYYQVKDAMRLLGVVSASPVLVSRIGIGGATAGWVIQEFTAQMRAVSRIA LHRRLNFAAFLETHGSGVIDGLMDVLWGILDLEQPDTQTINNIVIPSVELIYCYAECLAL NGSNASAKSVAPAVLLLKKLLFAPYEAVQTSSSLAISSRLLQVPFPKQTMLATDDVVESS ASAPVASDPTNANGGNTQIMLEEDSTTSSVQYCCDGCSTVPILRRRWHCNVCPDFDLCEA CFEVMDVDRLPPPHSRDHPMSAIPIEIDSLGEDGNEIHFAIDELSDPSLLHGTTNNNVQN SPPSVHQLEHNESGEFPASLIDQRIVTISAAKRAVNSLLLGELIEQLKGWMGTTSGARAI PIMQLFYRLSSAVGGPFMDSSKPENLDLEKFVRWFLDEINLSKPLILKMRSSFGEVVILV FMFFTLMLRNWHQPGSDSSLPKSGATSETQDKSVSQLASCPSTMGSSSANDDQDKSEFAS QLVRACSALRQQPFINYLMDILQQLMHIFKSPSSNLDPGHGLSSGSGCGALLTIRKELPA GNFSPFFSDSYAKAHRSDFFADYHRLLLENTFRLVYGLVRPEKVEKSGEKENVYKAPINK DLKLDGYQDVLCSYISNPHTTFVRRYARRLFLHLCGSKTHYYSVRDAWQLSSEIKKLFKL VNKSGGFQNPLLYERIVKLVKCLSVISELAGARPRNWQKYCSRHGDVLPFLLNGVFVFGE ESVIQALKLLRLAFHTGKDTGQAQQKGEVGDAATGSNKAGTQSSDSKKKKKSEEGSEASS EKSYIDMEQSVEIFTDKDGKVLQSFIDSFLLEWNSSAVRLEAKCVLYGAWHHGKRSFQET LLKELLQKMHCLPMYGQNITEFTELLTSLLGKGAPDNGLKLQETELANSCLTSDVLKCIF DTLRSQNELLANHPNARIYNTLSGLVEFDGYYLESEPCVACSCPEVPYSRTKLECLKSET KFTDNRIIVKCTGSYTIQSVTMNVHDARKSKSVKVLNLYYNNRPVADLSELKNNWSLWKR AKSCHLAFNQTELKVEFPIPITACNFMIELDSFYENLQASSLESLQCPRCSRYVTDKHGI CGNCHENAYQCRQCRNINYENLDSFLCNECGYSKYGRFEFNFMAKPSFTFDSMENDEDMK KGLIAIESESENAHRRYQQLLGFKKPLLKLVSSIGESEMDSQQKDTVQQMMVSLPSPSCK INRKIALLGVLYGEKCKAAFDSVSKSVQTLQGLRRVLMNYLHQKHSDDMMASSRFAVLRS PNHCYGCATTFVTQCLELLHVLSKYPHVKKELVGTGILSELFENNIHQGPKTARIQARAV LCAFSEGDASAVTELNNLIRKKVTYCLEHHRSMDIALATREELLLLSETCAVADEFWEAR LRVAFQLLFSSIKLGARHPSISENIILPCLKMVSQACTPPKSESVDKEQMSGKTTSVPPT KDDSSGDSHSSISGLANGNKSQSVSSEKHLDSYRKGQNIQLVSYSEWEKGASYLDFVRRQ YKVSPAVKPIQKSRKDSQRVDYLALKYVLRWKRRACKGTLKSAFSTFELGSWVSEIVLSA CSQSIRAEMCTLIGLLCAQNSSRRYRFLNLLMALLPATLSAGESSAEYFELFFKMIESED ARLFLAVKGCLSTICRLITVEVGNVESQERSLHIDISQGFILHKLIELLSKFLEVANIRA RFMRDELLSQVLEALLVIRGLVVQKTKLISDCNRLLKDLLDSLLLESSENKRHFIRACIS GLQIHGEERKGRTSLFILEQLCNMICPSKPEPVYLLILNKAHTQEEFIRGSMTKNPYSSS EIGPLMRDVKNKICHQLDLLGLLEDDYGMELLVGGNIISLDLSISQVYEQVWKKSHSQSP TLSTGLLSGGGFNSNRDCPPMTVTYRLQGLDGEATEPMIKELDEDREESQDPEVEFAIAG AVRECGGLEIILSMIQRLRDDELKSNQEELGSVLNLLMYCCKIRENRRALLKLGALGLLL ETARRAFFVDAVEPAEGILLIVESLTMEANESDIGISESVLAASNEGTSSGAGEQARRIV LMFLERLSHPSGLKKSAKQQRNNEMVARILPCLTYGEQAAMEVLIQHFEPHLQNWGEFDR LQKEHQDNPKDESLAEKAAAQRFAVENFVRVSESLKTSSSGERLMDMILERGITELAVDH LRERFSIVGQDDFKSSLEWASGLKLPSVPIILSMFKGLAVGHLRTQRCIEKGGILPLFHA LEGVSAENEIGARAENLLDTLADKEGKGDGYLGEAVHKLRHATRDEMRRRALKKREELLQ GLGMRQELASDGGERIVVTQPAIEGLDEVEEEEGGLACMVCREGYTLRPNDMLGAYSYCK RVNLGGGEYVYTTVSHFNVIHFQCHQEAKRADAALKNPKKEWEGAALRNNKTLCNCIFPL RGPAVPILQYSRCVDQYWDNLGSLGRADGSRLRLLTYDVVLMLARFATGASFSADSKGGG RDSNSRLLPFMLQMSCHLLDQPGSTQRCSLSKSISSYLSQNPSQSQLDPPKTPPTPKTPS PQSDETVQFMMVNSLLAEPYDVWAHHRLAFLQRGLHHAYAQYKQGRSTHFRLSPESSHRK DDPAMPGSSSGEDLFAIVQPMLVYTGLVEQLQRFFKPTEVSGKQESGAGKPEAGKEVEEL EGWEMAMREKLLNVREMVGFSKEVLGWLEEMQGAEDLQKAFDVAGILVDALSGGFSSVEE FVRASIAT NT seq 15327 nt NT seq  +upstreamnt  +downstreamnt atggctgaaattaagaagcttctggaccttcttactgaagaaaatgccatggtcgatctc tctcagaggttgcgatcggataatgcaaaattagggttatcggagttggcgtccatcata gaacaatccattaaagagaatgatgatggaaaattggtgtttcagatatggaatgagtca cagattgaatcccttttgtcagttttaagttatgttgtatatactactcgctcacttaca gttgaagctgcagaatcagcacttgttagggtttttgagagctctgtggagttctgcatt tattacgttgagaaatgtggacttaatggtgatcatggggctgacttacagaaaactgtt atacacctgctggaaatagctctacttgataaagtagatacagatttagattcagtgaag ttagattctccggctgttcttatggattgcttgccagtcatccctgctaattcaagcagg gtgaaacaggacagatacatgaagtgtaccctgcgagggatcaattgttcagtgaaagct gagccagtggacacagctatgcttgctttagcttctgagtatcttccagcgaataggcag gtttccctctcaactgaagatgtgccccatcaagactggaatagcatgatatctctttca cagcattgggcagttgttcatgggaagtgcatacctcgcctgattaatatatgcaaagag ctgttaaagccctcacagctctctgatgaacacaatggagattcacattttcagtcaata gtaatactttctaaaagaattctatcattagttgcaaggcttacaagggaagctccatat gttgcttctgatgtcgagttgttacttcaagcagcagccttggctgaattattgcctgag ttgtttaaacacaggcacgaccctctcaactttgattcttgtgctgaggagaaaagaatt gagcatcaccttatggtactaatggaggacttctttcattttgttgaagctgtttttcat agtgacaacatcttcctcaatataaagacatgtatttctgcttctatgttgaacatcttg gatacccaagtatggagttatgacaaacacagttccattcaaaagcctccattggttttt gcacctcaggttatcatgtatctcttgaagctcattggagaagtgcgtactcagacatgt caggtgcttagttggaagcagaaatctgatataaactccgttgaaaatttcatgaattca gagattggtgttgctccttcctttaatattagctccgagaaagtttctttggttgaaaga tataccagtgaacagcttcttaggcttatttttcctatcggaggtcactggcttgatgat ttaatacatcttgcctcttttcttcattcacaaggggtgaaatataaggtgaaaaatgac agattgcgccaagttcgtgcaaagagtcctgctccttctgacaaggatcctgcagtcagt catgaagatgatgctttgtttggggaccttttttgtgaacctggccgtcagggtgggatg actgatactcgtgatcaaccacctgttgcctctgatatgataaatattggcaccaacata ccccttcaaggtgctattgagctactgacttttcttaaaagctccatcttttcccctgaa tgggatagttctgtttgcaaggaagcatgcgtgatgcttcatgagaggcatataagcatc ttactttccatgctccagttccaagtttgcctgtttgacgaagggatacccaatagtgca gtttcggcatgccagaaacagctcgggcatgtttctgatgtaagctttgacctattgtac agcctccttgcacgcagagctttatccaggtgccttgaagaacaccttgctagccaaatt ctcaaggtagagaagggacactttgtctataatgactatactcttgttttgttagctcac gctatgatttctagggttggtcttagtgggagactttttagaatcaaagtttttgaagca tatattgatttcattcttgaaaaggcaaatgatgtgtgctcaaattgccccagtcttgga gatacatttgcaggtctcccttctcttttccactttgaaattcttcttatggctttccac tcgtcctcggtttcggagaaagtttcctttgcaaagagggtgtttgatgctcttcaggca gtaagccatactccagctgaattcagctgcacactattgacagcttggtctttgctagta tcacggttgattttgattctgcgtcatatgatctattacccatcaacatttccttcgtgg cttctttcacatattcgaaccaagttgagggaagtgccatctcgaggaagctcttctggg attgtaaatgatcgtttactatcatgggtatccactaccatacaaagtatcatggctgta tgggttaaagatcgaccagtactcggtaatttgcttcctctattgatagatgttgttcct gttcctaattcagcttctttagatggccaagtccttcaagatctaggtctgaatcaggat gatgtacatgatgccttctcacaaatattaggattgtggaaaggtaagaaagctgaagca gtggaagacctcgttcttgaaaggtactgttttctactttgttgggatacactatcttgt attaggtctccatcagtgagagttgacacttggagccttgatttgggaagaatggattct ttcattcaattcagccatttcctggtaagcaaggctgatgttaccagctatattggtagt ggaaacttcacagaagttgtcaccagtgtccttcaacagcttagtattacccatgaacca tttcaagttaaagagagaacttgggactttttaagggatggagcttggctctctctgatt ctttctttgcttcaagttggcatcgggaggttttctgaaaaggatgcattgcaaggactg gaatcatgttgggtggaagatatacacgggggcaactatttcttgtcgatcgctgaaagt gttgtggttgctttgtttcaaaataaccaggttggatccgtgattgagtggctttcagtt ctattgcatagatatttgcacgcccttcaagaggcatttgttatggcccttgatcgccag gaatgtgaggtgggcttgttttcttcatcgcttcttctcatacaatctggatgtgaacaa tgccctgaggctgagctgctggagaaaattggagccagccctgccctgctagaatatctg tatggtcttgggtcaaaattgaatgagcttgttgagagagaagatttagagaacctgagt cgagcgttccgcagatccttgttgcatggttttccttcacatttacaaactaatagtggg gctcttctttcttgtattgtctctgtggaagggataatctgcacattcgagagcttaatc aaggtcaaagattctacaggggctatacatatagacgatgatgtgctgctccgtcttctt gattcagtcatgatggttaaacttggaaggatttttgaacatatacatggaaagcttgat gttatatacagctacttcttcccatctgagaaagggaacttggatcatagtgtgttgttc ttactgaagcacatggaaaattttctcaaggaagtggtttccagagagaaaataaacttg ggtgttcttgaagttctaataaaaaatactgttgatttggttgaccgcatcaggaaagac ccagctaaagttgacagtctaaaatgctatttgggcatcaacaatgacaagaataaagag gccaagaagctttaccctatacagaatggcaatctattggttcttttggatgtcttggat acttgtcacactgaagcagtgagtatgaagattctgcaattgtttaatgatcttttgtct ggagagctttgttgtagccttaaagtggaagcacaaaagaaattcttgggaatggatttg gcatgtttatccaaatggcttgaaaagaagttgttgggatgcatgattgaaacttcagga ggagtttcgacagccaaaggaagccctgttgcactcagagaactgactctgaatgtcata atctgccttgtatcaccatcttctgagattaattcgaaagaacttcgtcttcactttgtt gaagcaatgcttatgtccctagaggatgcgttcatgcaatttgacattcatacagccaag gcttatttcaattctatctttcagctctgtaatggagattcttcaatgaggcatcttgtg gagaaaactgtgaggctgatggacaaatttttgtgtgatgaacgattcctggaaggctta aaatttctttttggttttctctggagtatcctaagtgcatgtggagctaataaaggcact ggggataagttttcaggtaagcattggtcgagcagtagttctggagctgcatccactatt cctagaacagttggcagtgtctcaagccaaggttcagagacattggttcttccctcaagt caggagtctggttctgctacggttgactgcgatgcaacttcagttgatgaagatgaagat gatggtacatcagacggggaattggctagtgtggacaaggatgatgatgatgatagtaac aatgaaagggcccttgcatctaaagtttgcacattcacttcaagcggcagcaacttcatg gagcaacactggtatttttgttacacatgtgatctaactgtttccaaaggttgctgttct gtttgtgcaagggtgtgccatcgaggtcaccgtgttgtctattctcgctcgagtcgtttc ttttgtgattgtggggcaggtggtgttagaggaagcagctgccagtgcttgaagcctcgt aaatatactccttccaatagcgctccagttcgagctacaaataattttcagccattcctt tctttctctgaagatggagaattacctcctgatagtgattcagattttgatgaagatggg cttgcagacattgagagctctttcaaattatccatcccaaaggaggaacaagaaggactt gcacgcttgctgatgaatgttgatgttgagagtctgcttattcagctttgcagtagatta ctaccagctgtaacaggcagaagagagtgtaatctctcaaaagatcagaaagtggtattg ggggatgataggattttgtcatacaacactgatcttttgcaactgaaaaaggcatacaaa agtggatcattggatatgaagatcaaggcagaatattcaaatgcaagggaactgaaaacc catctggttaatggttccctaatcaaatctttgctcagtgttagcaggcgtggcagactt gctgctggggagggtgacaaagttgcaatttttgatgtggggcagctaattggacagcca tcagttgcacccataacagcagataagaccaatgtgaagcctctttcaaaaaacattgtt cgctttgagatagttcatattcttttcaaccccttggtagaaaattatcttgctgttgca ggttatgaagaatgccaagtccttactgttaatcaccgtggggaagtgactgatcgtctt gctgttgaacttgcttctcaaggtgcttatattcggcggatagattgggttcctggttct caagtgcaactgatggggatcactaacacttttgtcaagatctatgatctgtctcaagat aatataagtcccatgcattacttcaccttggatgatgatctgattgtggatgcgacactt gttactgcacctcaggggaaaatatttcttcttgttctctcagaacttggtcgcttattc aggcttgaattgtctatgggaggtgacgtgggggctaaacaaatgactgatatcatcgaa cttgataaagctccacattcgagaggtctttctttgtacttctcatcaaccttccgattc cttttcttgtcctatcaggatggtactaccttgattggccgcctggatgccaatgcaaag actcttactgaaatatctgccatttatggggatgagcaggatggtaaattgaggcctgct gggctgcaccattggaaagagatgcttgatggtagtggtttctttgtttgcttctcttct ctaaagttgaattcgatacttgctgtatctataggagtccatgagttactagcacaaaac ttgcgacatactggaggaagctcatcactatctcttgttggtatagccgcatacaggcct ttatcgaaggacagaacccactgccttgttctatatgatgatggaagcctgcagatatat tcagctaattctttgggatccaattctggatcgaatttgacctcagatcatgccaaaaaa ttaggatctggaatcctcagcagcagagtatgttctggttccaatccagagttccctctc gacttctttgagaaaactgtttgcatttcacctgatgtgaagttgggaggtgatgccatt agaaatggtgattcagagagtgctaagcaaaatttggtatcggatgatggctatctagaa agtcccagcgcttctggttttaagataatcgtcttcaattcaaatcctgatattgccatg gttggtttccgtatacatgtcggaaatacttcagcaagtcatattccttctgagatcacc attttccagagagttattaaactggatgagggtatgcgttcatggtatgacatcccattc actactgctgaagcacttttggctgatgaagaatttacaatctctgttggcccgaccttt aatggctctactttacccagaatagattctttagaagtttatggtcgacttaaggatgac ttcggttggaaggaaaaaatggatgctgttttagacatggaggcccatgtactcggtgcc acatctggggtttctgggcatggaaagaagtatcggccattgcaagctgtttcattgcaa gaacaggttatagcagatggacttaagctcctatctgcatattattccttgtttaggtct caggcatgcgctgaaattgaggatgcaaagatagaatcctgtaaactgaaatgcaagaag ctattggaaacaatatttgaaaatgacagggagattatgttacaatgtgctgcctgccat gttcttcagacgttgttcccaaaaaaggagatgtactatcaggtcaaagatgctatgcgt cttcttggtgttgtaagtgcttcgccagtccttgtctcaaggataggaattggtggagca acagctggatgggtaattcaagagtttacagcccaaatgagagctgtgtctaggattgct ttgcatcgtagattgaattttgctgcttttctggaaactcatggttctggcgtaattgat ggacttatggatgttctttggggaatactggacttggagcaacctgacacacaaactatc aacaacattgtcataccctctgtggagctgatctattgctatgcagaatgcttggcttta aatggaagcaatgcatctgcaaaatctgtcgcacctgctgttctattgctcaagaaactt ctttttgctccttacgaggctgtacagacttcaagcagcttggctatatcatctaggctg ctccaggttccatttccaaagcagacaatgttggccactgatgatgttgtggagagtagt gcatcagcccctgtagcttctgatccaaccaatgcaaatggtgggaacacacaaatcatg cttgaagaagactctaccacgtcatctgttcaatattgctgtgatggttgctccactgtt cctatacttcgacgaagatggcattgtaatgtttgccctgacttcgatctatgtgaagct tgctttgaagtaatggatgtagataggcttcccccaccacattctagagatcaccctatg tctgcaattcctattgaaattgattctcttggggaagatgggaacgaaattcactttgca attgatgaactaagcgatccaagtctacttcatggcactaccaataacaatgtgcaaaat tcacctccgtccgttcatcaattggagcataacgaatctggagagttccctgcttctcta attgatcagagaatagtgacaatttcagctgcaaagagagccgtgaattcattgttactt ggcgagctgatagagcagctgaaagggtggatgggaacaacttctggtgctcgtgctata cccattatgcaactgttctacaggttgtcatctgcagtgggtggacctttcatggatagc tcaaagcctgaaaatttggatttagagaaatttgtgaggtggtttttggatgagatcaac ttgagtaaacctcttatacttaaaatgcgttcatcatttggggaagtcgttatccttgtg ttcatgttcttcaccttgatgcttcgaaactggcaccagcctggcagtgacagttctcta ccaaaatcgggggcgacttctgagacacaagataaatctgtttcccaattggcatcatgc ccctcgactatgggttcctcatctgcaaatgatgatcaagacaaaagtgagtttgcttct cagctggttcgagcttgttctgctcttaggcagcagccttttatcaactaccttatggat atactacaacagctgatgcatatttttaaatcaccttcttcaaatcttgaccctgggcat ggattatcatctgggtcgggttgtggtgcattgctcactattcgtaaagaattgccagct gggaacttttctcctttcttctcagattcatatgccaaagcccataggtcagattttttt gccgattatcacaggcttctgttagagaatacttttcgtttggtatatggcttggttagg cctgaaaaagtagaaaaatctggggaaaaggagaacgtctacaaggctcccatcaacaag gatttaaaactagacggttatcaagatgtcctttgtagctacatcagcaatcctcacaca acatttgtgaggcggtatgcgaggaggcttttcctgcatttgtgtggaagcaaaacccac tattacagtgtaagagatgcatggcagctatcaagtgaaatcaagaaactcttcaagctt gtaaataaatctggtggttttcagaaccctctcctatatgagagaattgtgaaactggtt aagtgcttgtctgtgatatctgagttagcaggggctagaccaagaaactggcaaaaatat tgctcgaggcatggagatgttctccccttcttgctgaatggtgtcttcgtttttggtgag gagtctgtcatccaagctcttaaacttttgcgcttggcatttcatacagggaaggataca ggccaagctcaacagaaaggagaggtgggagatgcggcaacgggctctaacaaagctgga acacaatcttcagattcaaagaagaaaaagaaatcagaagaaggaagtgaagctagctct gagaaatcttatattgacatggaacagtcagttgaaatcttcactgacaaggatgggaag gtcctacagagctttattgattcatttttgctggaatggaactcatcggctgttcgcctt gaggccaaatgtgttctttatggtgcttggcatcatggcaaacgatcttttcaggagacg ctgctgaaggaacttcttcagaaaatgcattgtctccccatgtatggccaaaatatcacg gagttcacagagctcctgacatctttactgggaaagggagctcctgataatggtctgaaa ctccaggaaacagaacttgcaaattcatgcttgacttctgatgtattgaagtgtatcttt gatacacttcgttcccagaatgagcttctggccaatcacccaaatgctcgtatttacaat actctgagtggtttggttgagttcgacggctactatcttgagagtgagccctgtgttgcg tgtagctgtcctgaggttccttacagtcgcacaaagttggaatgtttgaaatctgagaca aaattcactgacaatcgcattatagtgaaatgtactggaagttacacaattcaatcggtg accatgaatgtgcatgatgctcgcaagtcaaagtcggtgaaggttttgaacttgtattac aacaataggcctgttgctgatctttcagaactaaaaaataattggtctctgtggaaacgt gcaaagagttgccatcttgccttcaatcaaacagagctgaaggttgaattccctattccc ataactgcctgcaacttcatgattgaactggactcattttatgagaatctccaagcttct tctcttgagtccttgcagtgccctcgctgcagtcgttatgtcactgataagcatgggatc tgtggcaactgtcatgaaaatgcctatcagtgcaggcagtgccgtaacataaattatgag aatttggattctttcctgtgcaatgagtgtgggtatagcaaatacggtcgttttgagttc aatttcatggcaaagccaagtttcacttttgatagcatggagaatgatgaggacatgaag aaagggctcatcgcaattgaatcagaatcagaaaatgctcataggagatatcaacaactt ctgggatttaagaaacctttgcttaagcttgtatctagcatcggtgagagcgaaatggat tctcaacagaaagatacagttcagcagatgatggtctccttgcccagtccttcttgtaaa ataaacaggaagattgctcttcttggtgttttgtatggtgagaagtgcaaagctgctttt gattcagtgagcaagagtgtccagactctccagggccttcgtcgggttttgatgaactat ttgcaccagaagcattcagatgatatgatggcctcatcgagatttgcagttcttaggtct ccaaatcattgttatggatgtgccactacatttgttacccaatgtttggaactgttgcat gtgttgtcaaaatacccacatgttaagaaagagcttgttggtactggcatattgtctgag ttgtttgaaaacaatattcatcagggccccaagacggctcgcattcaggcaagagctgtt ctttgtgcattttcagagggtgatgcaagtgcagtgactgagttaaacaatctgataaga aagaaggtcacatattgcctagagcaccatcgttctatggatattgccttggcgactcgt gaggagttgctattactttctgaaacttgtgctgttgcagatgagttctgggaagctaga ttgcgagttgcttttcagctgttattctcttcgatcaagttgggtgcccggcatccttct atttctgagaacattattttaccatgcttgaaaatggtatctcaggcttgcacccctcca aaatctgaatcagttgataaggagcaaatgtcggggaaaaccacatcagttccaccgaca aaggatgacagtagtggagattcacactcatctataagtggccttgctaatgggaataag tcacagtctgtatcatcagaaaagcacttggatagctacaggaaagggcagaatattcag ttagtaagctattccgagtgggaaaaaggagcctcttatcttgacttcgtgaggaggcaa tacaaagtctcgccggcagtcaaacctattcagaagtctcgaaaagactcccaaagggtc gattatcttgctcttaaatatgtcctgagatggaaaaggcgtgcttgtaaaggaacgctt aagagtgcattctcaacattcgaactgggatcatgggtttctgaaatagtcttgagtgca tgttcacagtctataagggctgagatgtgcacgttaattggtttgctttgtgctcagaat tcatctaggcggtatagatttttgaacttactgatggcgcttcttccggctactctttct gctggggaaagttctgctgagtacttcgaactatttttcaagatgattgagtcagaagat gcaaggttgtttctcgctgtaaagggatgcctgagtactatatgtaggttgataactgtc gaggtgggaaatgtggagtcacaagaaaggagcctacatatagacatatcacagggcttt attctacacaagctcattgaacttctcagcaaatttcttgaagtggcaaatattcgagca aggttcatgcgagatgagcttctgtctcaagtattggaggctcttcttgtcatccggggt cttgtagtacaaaaaacaaaattgataagtgattgcaatcggctattgaaggatctcttg gacagtcttctgcttgagagcagtgaaaacaagcgccatttcatacgagcctgcatttct ggtttacagatccatggagaagaaagaaagggacgaacatctctgtttattttggagcag ctttgcaacatgatatgcccatcaaagccggagccagtctatttattaatactgaacaaa gcacatactcaggaggagttcatccggggttcaatgactaagaatccttactccagttca gagattggtccattgatgcgtgatgtcaagaacaaaatttgccatcagttggacttgtta ggtctccttgaggatgactatggtatggaattgcttgtgggtggcaatataatatctctg gatctcagcatttctcaagtttatgagcaggtctggaagaaatcacatagtcaatcacca actctcagtactggcttgctatctggtggtggatttaattccaatagagattgcccacct atgacagtgacttacaggcttcagggattagatggtgaggctacagagcctatgatcaag gaattggatgaggatagggaggaatcacaggaccctgaagttgagtttgctatagctggt gctgtgcgggagtgtggtggactggaaataattttgagcatgatccagcggctgagggac gacgagctcaagtctaatcaagaggagctgggatcagttctcaatctcctcatgtattgc tgcaagattcgggagaacaggcgtgccttattaaagctaggtgcactgggcctcctcttg gagacagctaggcgtgccttctttgtcgatgctgtggagcctgcagaaggcatactcctg attgttgagagcttgacgatggaggctaatgagagtgacattggcatctcagagagtgtg cttgctgcttccaatgaaggcacaagctcgggggccggtgagcaagcaagaaggatagtc ttgatgttcttagagcggctttcccacccttctggcctcaaaaaatcagcaaagcagcaa cgaaacaatgagatggtggctcgaatacttccctgtctcacatatggagaacaagctgcc atggaagtgctgatacaacactttgagcctcatttgcaaaattggggagagtttgatagg cttcagaaggagcaccaagacaaccctaaagatgagagcttggctgagaaagcagctgct cagaggtttgctgtagagaactttgtgagagtatctgagtcacttaaaacgagctcgtct ggagagagactcatggacatgattctagagagagggattactgaattagctgtcgaccat cttagagagagattttccattgttgggcaggatgatttcaagtctagtttggagtgggca agtggtttgaagctaccatctgttccaataattttgtcgatgttcaaggggcttgcagta ggccatttgaggacacaaaggtgcatcgaaaagggcggtatcttgccattgtttcatgct cttgagggagtttcagcggagaatgagattggcgcaagagccgagaacttgcttgatacg ctagctgacaaggaggggaagggggatggataccttggggaagcagtgcacaagctaagg catgcaacgcgggatgagatgcggcgacgggctctgaaaaagcgagaggaactattgcag ggtcttgggatgcgacaggagctagcatctgatggcggagagcgcattgttgttacccag ccagccattgagggcctagatgaagtcgaagaggaggaaggtggccttgcttgcatggtg tgtagagaaggatatacactccggcccaatgatatgcttggtgcctactcttattgcaag agggttaacttagggggtggtgaatacgtatacacaacagttagccacttcaatgtcatc cattttcagtgtcaccaagaggccaaacgggcagatgcagcactcaaaaaccctaaaaag gagtgggaaggtgcggcactccgaaataacaagactctgtgtaattgcatctttccactt agggggcctgctgtgcctattttgcaatatagtcgttgtgttgatcagtattgggataac cttggctcacttgggcgggctgatggtagcaggctgcggcttctcacttatgacgttgta ctgatgctggctcgcttcgcaacgggtgcctctttcagtgccgacagcaagggtgggggg cgcgatagcaactctcgcctccttcctttcatgctccagatgagctgccacctcctcgac caacctggatctactcaacgatgttccctttccaaatccatctcttcctatctctctcaa aacccatctcaatcacaattggacccaccaaaaacccctcctacccctaaaacgccttct ccccaaagtgatgaaacagtccaattcatgatggttaattccctccttgctgaaccttac gatgtgtgggcccatcatcggcttgcctttctccaacgcgggctccaccatgcctatgcc caatacaagcaaggcagatctacccacttccgcctctcacccgaatccagccatcgaaaa gatgatccagcgatgcctggctccagtagtggtgaggacctcttcgcaatagtgcaacca atgcttgtatatacaggtctcgttgagcagttacaaagattctttaagcccacagaggtt tccggaaagcaggaatcaggtgccgggaaacctgaagctggaaaagaggtggaggagttg gaggggtgggagatggcgatgagggagaagctgctcaatgttagagagatggtgggtttc tctaaagaagtgttggggtggctcgaggaaatgcaaggggctgaggatttgcaaaaggct tttgatgtggctggaattttggtggatgctctttctggtgggttttcaagtgttgaggag tttgttcgggcttccattgctacctga

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