KEGG   Bos indicus (zebu cattle): 109553833Help
Entry
109553833         CDS       T04792                                 

Gene name
HK1
Definition
(RefSeq) hexokinase-1
  KO
K00844  
hexokinase [EC:2.7.1.1]
Organism
biu  Bos indicus (zebu cattle)
Pathway
Glycolysis / Gluconeogenesis
Fructose and mannose metabolism
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Neomycin, kanamycin and gentamicin biosynthesis
Metabolic pathways
Carbon metabolism
HIF-1 signaling pathway
Insulin signaling pathway
Type II diabetes mellitus
Carbohydrate digestion and absorption
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:biu00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    109553833 (HK1)
   00051 Fructose and mannose metabolism
    109553833 (HK1)
   00052 Galactose metabolism
    109553833 (HK1)
   00500 Starch and sucrose metabolism
    109553833 (HK1)
   00520 Amino sugar and nucleotide sugar metabolism
    109553833 (HK1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    109553833 (HK1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    109553833 (HK1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    109553833 (HK1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    109553833 (HK1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    109553833 (HK1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    109553833 (HK1)
Enzymes [BR:biu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     109553833 (HK1)
Membrane trafficking [BR:biu04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    109553833 (HK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
LinkDB All DBs
Position
28
AA seq 889 aa AA seqDB search
MRLSDETLLDIMNRFKKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS
SFRILRVQVNHEQNQAVHMESEVYDTPENIMHGSGSQLFDHVAECLGDFMEKKKIKDKKL
PVGFTFSFPCRQSRIDEAILITWTKRFKASGVEGTDVVKLLDKAIKKRGDYDANIVAVVN
DTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCVNTEWGAFGDDG
ALEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPEL
LTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVAVQHVCTIVSFRSANLVAA
TLGAILSRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDCDVRFLLSESG
SGKGAAMVTAVAYRLAEQHRQIEETLAHFSLTKEMLLEVKKRMRAEMELGLGKQTHDKAV
VKMLPSFVRSTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRSVEMHNKIYAIPIEIMQ
GTGEELFDHIVSCISDFLDYMGIKGPKMPLGFTFSFPCKQTSLDAGILITWTKGFKATDC
VGHDVATLLREAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYME
EMKNVETLEGNQGQMCINMEWGAFGDNGCLDDIRTIYDKLVDEFSLNSGKQRYEKMISGM
YLGEIVRNILIDFAKRGFLFRGQISEPLKTRGLFQTKYLSQIESDRLALLQVRAILQQLG
LNSTCDDSILVKTVCGVVSKRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLH
PHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRQEMSS
NT seq 2670 nt NT seq  +upstreamnt  +downstreamnt
atgcggctctctgatgaaactctgttagatatcatgaatcgtttcaaaaaggagatgaag
aatggcctctcccgggattttaatccgacagccacagtcaagatgttgccaacgtttgta
aggtctattcccgatggctcagaaaagggagatttcatcgccctggatcttggcggatct
tcctttcgaattctgcgggtgcaggtgaatcacgagcagaaccaggctgttcatatggag
tctgaggtttacgacaccccggagaacatcatgcatggcagtggaagccagctttttgat
cacgtcgctgagtgcctgggagacttcatggagaaaaaaaaaatcaaggacaagaaatta
cctgtgggattcacattttctttcccttgtcggcaatccagaatagacgaggccatcctg
atcacctggacaaagagatttaaagcgagcggcgtggagggaactgatgtggtgaagctg
cttgacaaagccatcaaaaagcgtggggactatgatgccaacattgtggctgtggtgaac
gacacggtggggaccatgatgacctgtggctacgacgaccagcagtgtgaagtcggcctc
atcattggtaccggcaccaacgcgtgctacatggaggagctgagacacatcgacctggtg
gagggcgacgaggggaggatgtgcgtcaacaccgagtggggggccttyggggacgacggg
gccctggaggacatccgcaccgagttcgaccgggagatagaccgggggtcgctcaacccc
gggaagcagctgtttgagaagatggtcagtggcatgtacctgggcgagctggtccgactg
atcctggtcaagatggccaaggagggcctcttatttgaagggcggatcaccccagagctg
ctcaccagagggaagtttaacaccagtgacgtgtcggccatcgaaaagaataaggaaggc
ctccacaatgccaaagaaatcctgacccgcctgggagtggagccgtctgatgacgactgt
gttgcggttcagcacgtgtgcaccatcgtctcatttcgctctgccaacytggtggcggcg
accctgggtgccatcttgagccgccttcgagataacaagggcacgcccaggctgcggacc
acggttggtgtcgacgggtccctttacaagacgcacccacagtattctcggcgtttccac
aagactctgcggcgcttggtacccgactgtgatgtgcgtttcctcctctccgagagcggc
agtggcaagggggccgccatggtgactgccgtggcctaccgcctggctgagcagcaccgg
cagatagaggagaccctggcccacttcagcctcaccaaggaaatgctgctggaggtgaaa
aagcggatgcgggctgagatggaattggggctgggcaagcagacgcatgacaaggctgtg
gtcaagatgttgccctccttcgtccggagcactcctgatgggactgagaacggtgacttc
ttggccctggatcttggaggaacgaatttccgcgtcctgctggtgaaaatccgtagtggg
aaaaagagatcagtggaaatgcacaataagatctacgccattcccattgaaatcatgcag
ggcactggggaggagctgtttgaccacatcgtttcctgcatctctgacttcctggactac
atgggcatcaagggccctaaaatgcctctgggcttcacattttcgtttccctgcaagcag
acgagcttagatgcgggtatcttaatcacctggaccaaaggttttaaggcaaccgactgc
gtggggcatgatgtagcaaccttactgagggaggcgataaaaaggagagaggaatttgac
ctggatgtggtggctgtggtcaacgacacggtgggcaccatgatgacctgtgcttatgag
gagcccacctgcgaggttggactcatcgtagggactggcagcaatgcctgctacatggag
gaaatgaaaaacgtcgagacgctagaaggaaaccagggacaaatgtgtatcaacatggag
tggggtgcctttggggacaacgggtgtctggatgatatcagaacaatctatgacaaactg
gtggatgagttttctctaaactctgggaagcaaaggtatgagaagatgatcagcggtatg
tacctgggtgagattgtccgcaacatcttgatcgacttcgccaagaggggcttcctcttc
cgggggcagatctctgagccgctgaagacccggggcctctttcagaccaagtatctctct
cagatcgagagcgaccgattagcgctgctgcaggtccgggccatcctccagcagctgggc
ctgaacagcacgtgtgacgacagtatcctcgtgaagaccgtgtgtggggtggtgtccaag
agggcggcgcagctgtgtggcgcaggcatggctgctgtggtggataagatccgcgaaaac
agggggctggaccgcctcaacgtgactgtgggcgtggacgggacgctctacaagcttcat
ccgcacttctccagaatcatgcaccaaaccgtgaaggaactgtcaccaaagtgtaatgtg
tccttcctcttatctgaagacggcagcggcaagggagccgccctcatcacagcggtgggc
gttcggctccggcaagaaatgagcagctaa

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