KEGG   Bos taurus (cow): 280817Help
Entry
280817            CDS       T01008                                 

Gene name
HK1
Definition
(RefSeq) hexokinase 1
  KO
K00844  
hexokinase [EC:2.7.1.1]
Organism
bta  Bos taurus (cow)
Pathway
Glycolysis / Gluconeogenesis
Fructose and mannose metabolism
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Neomycin, kanamycin and gentamicin biosynthesis
Metabolic pathways
Carbon metabolism
HIF-1 signaling pathway
Insulin signaling pathway
Type II diabetes mellitus
Carbohydrate digestion and absorption
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:bta00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    280817 (HK1)
   00051 Fructose and mannose metabolism
    280817 (HK1)
   00052 Galactose metabolism
    280817 (HK1)
   00500 Starch and sucrose metabolism
    280817 (HK1)
   00520 Amino sugar and nucleotide sugar metabolism
    280817 (HK1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    280817 (HK1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    280817 (HK1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    280817 (HK1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    280817 (HK1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    280817 (HK1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    280817 (HK1)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     280817 (HK1)
Membrane trafficking [BR:bta04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    280817 (HK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
UniProt: 
LinkDB All DBs
Position
28
AA seq 917 aa AA seqDB search
MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLLDIMNRFKKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEQNQAVHMESEVYDTPENIMH
GSGSQLFDHVAECLGDFMEKKKIKDKKLPVGFTFSFPCRQSRIDEAILITWTKRFKASGV
EGTDVVKLLDKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCVNTEWGAFGDDGALEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCVAVQHVCTIVSFRSANLVAATLGAILSRLRDNKGTPRLRTTVGVDGSLYKTH
PQYSRRFHKTLRRLVPDCDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFSLT
KEMLLEVKKRMRAEMELGLGKQTHDKAVVKMLPSFVRSTPDGTENGDFLALDLGGTNFRV
LLVKIRSGKKRSVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPKMPLGF
TFSFPCKQTSLDAGILITWTKGFKATDCVGHDVATLLREAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVETLEGNQGQMCINMEWGAFGDNGCLDD
IRTIYDKLVDEFSLNSGKQRYEKMISGMYLGEIVRNILIDFAKRGFLFRGQISEPLKTRG
LFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAA
VVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLRQEMSS
NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt
atgatcgccgcgcagctcctagcttattacttcaccgaactgaaggatgaccaagtcaaa
aagattgacaagtatctctatgccatgcggctctctgatgaaactctgttagatatcatg
aatcgtttcaaaaaggagatgaagaatggcctctcccgggattttaatccgacagccaca
gtcaagatgttgccaacgtttgtaaggtctattcccgatggctcagaaaagggagatttc
atcgccctggatcttggcggatcttcctttcgaattctgcgggtgcaggtgaatcacgag
cagaaccaggctgttcatatggagtctgaggtttacgacaccccggagaacatcatgcat
ggcagtggaagccagctttttgatcacgtcgctgagtgcctgggagacttcatggagaaa
aaaaaaatcaaggacaagaaattacctgtgggattcacgttttctttcccttgtcggcaa
tccagaatagacgaggccatcctgatcacctggacaaagagatttaaagcgagcggcgtg
gagggaactgatgtggtgaagctgcttgacaaagccatcaaaaagcgtggggactatgat
gccaacattgtggctgtggtgaacgacacggtggggaccatgatgacctgtggctacgac
gaccagcagtgtgaagtcggcctcatcattggtaccggcaccaacgcgtgctacatggag
gagctgagacacatcgacctggtggagggcgacgaggggaggatgtgcgtcaacaccgag
tggggggcctttggggacgacggggccctggaggacatccgcaccgagttcgaccgggag
atagaccgggggtcgctcaaccccgggaagcagctgtttgagaagatggtcagtggcatg
tacctgggcgagctggtccgactgatcctggtcaagatggccaaggagggcctcttattt
gaagggcggatcaccccagagctgctcaccagagggaagtttaacaccagtgacgtgtcg
gccatcgaaaagaataaggaaggcctccacaatgccaaagaaatcctgacccgcctggga
gtggagccgtctgatgacgactgtgttgcggttcagcaygtgtgcaccatcgtctcattt
cgctctgccaacctggtggcggcgaccctgggtgccatcttgagccgccttcgagataac
aagggcacgcccaggctgcggaccacggttggtgtcgacgggtccctttacaagacgcac
ccacagtattctcggcgtttccacaagactctgcggcgcttggtacccgactgtgatgtg
cgtttcctcctctccgagagcggcagtggcaagggggccgccatggtgactgccgtggcc
taccgcctggctgagcagcaccggcagatagaggagaccctggcccacttcagcctcacc
aaggaaatgctgctggaggtgaaaaagcggatgcgggctgagatggaattggggctgggc
aagcagacgcatgacaaggctgtggtcaagatgttgccctccttcgtccggagcactcct
gatgggactgagaacggtgacttcttggccctggatcttggaggaacgaatttccgcgtc
ctgctggtgaaaatccgtagtgggaaaaagagatcggtggaaatgcacaataagatctac
gccattcccattgaaatcatgcagggcactggggaggagctgtttgaccacatcgtttcc
tgcatctctgacttcctggactacatgggcatcaagggccctaaaatgcctctgggcttc
acattttcgtttccctgcaagcagacgagcttagatgcgggtatcttaatcacctggacc
aaaggttttaaggcaaccgactgcgtggggcatgatgtagcaaccttactgagggaggcg
ataaaaaggagagaggaatttgacctggatgtggtggctgtggtcaacgacacggtgggc
accatgatgacctgtgcttatgaggagcccacctgcgaggttggactcatcgtagggact
ggcagcaatgcctgctacatggaggaaatgaaaaacgtcgagacgctagaaggaaaccag
ggacaaatgtgtatcaacatggagtggggtgcctttggggacaacgggtgtctggatgat
atcagaacaatctatgacaaactggtggatgagttttctctaaactctgggaagcaaagg
tatgagaagatgatcagcggtatgtacctgggtgagattgtccgcaacatcttgatcgac
ttcgccaagaggggcttcctcttccgggggcagatctctgagccgctgaagacccggggc
ctctttcagaccaagtatctctctcagatcgagagcgaccgattagcgctgctgcaggtc
cgggccatcctccagcagctgggcctgaacagcacgtgcgacgacagtatcctcgtgaag
accgtgtgtggggtggtgtccaagagggcggcgcagctgtgtggcgcaggcatggctgct
gtggtggataagatccgcgaaaacagggggctggaccgcctcaacgtgactgtgggcgtg
gacgggacgctctacaagcttcatccgcacttctccagaatcatgcaccaaaccgtgaag
gaactgtcaccaaagtgtaatgtgtccttcctcttatctgaagacggcagcggcaaggga
gccgccctcatcacagcggtgggcgttcggctccggcaagaaatgagcagctaa

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