Bos taurus (cow): 519037
Help
Entry
519037 CDS
T01008
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
bta
Bos taurus (cow)
Pathway
bta00562
Inositol phosphate metabolism
bta01100
Metabolic pathways
bta04014
Ras signaling pathway
bta04015
Rap1 signaling pathway
bta04020
Calcium signaling pathway
bta04024
cAMP signaling pathway
bta04070
Phosphatidylinositol signaling system
bta04919
Thyroid hormone signaling pathway
bta04933
AGE-RAGE signaling pathway in diabetic complications
bta05205
Proteoglycans in cancer
Module
bta_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
519037 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
519037 (PLCE1)
04015 Rap1 signaling pathway
519037 (PLCE1)
04020 Calcium signaling pathway
519037 (PLCE1)
04070 Phosphatidylinositol signaling system
519037 (PLCE1)
04024 cAMP signaling pathway
519037 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
519037 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
519037 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
519037 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
bta04131
]
519037 (PLCE1)
Enzymes [BR:
bta01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
519037 (PLCE1)
Membrane trafficking [BR:
bta04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
519037 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
519037 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
519037
NCBI-ProteinID:
NP_001192781
BGD-bta:
BT18838
Ensembl:
ENSBTAG00000018966
VGNC:
32987
UniProt:
F1MTE8
LinkDB
All DBs
Position
26:15469822..15850186
Genome browser
AA seq
2297 aa
AA seq
DB search
MTSEEMAGSVLRPVSQRKVISAQSTVDESNDKVSGISVPKSHPVRQSGETSHTISQPTKL
TEESSGSNAPQIFSVAREKITSDENSNEKCWEKSMPDSVKNLNINCNSILKNHQHGPPQS
QFYETCNSITEEGLCLETGIPSSLEGKVFPGIQLEIDTSPMGMSPLGTQSAIIETSRAHP
ESNMAVFHLRYEVDRRMSDSFCPLSDNLILDDCGNCVLPAVGEEQEKNYMAYTCKLMELT
NNCDNKNRQLQCDHCDPLNDKYLCFEGSCPKADVVCSSDSFCREDFTDSPPAKTFLSHFE
DFPDNCEEVEEDLFKNKKERSAWLVRRFCKNDKEVKKSVFTGTRAIVRTLPSGHIGLEAL
SYIDQKKNGLLLPPGRVMERLSTMVVRQDGSQGLSEAQWYPIYSAVRRGEATEQTIRSLL
HFFAKLPASETAHERISVGPYLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGAR
SSLLNSFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLKPLIQFPEEVASILM
EQEQNIYRRVLPVDYLFFLTRGLGTTERQRSLPCLKASISASILTSQKGEHNALEDLVMR
FNEVSSWVTWLILAAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
QFMDQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA
SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRS
LETEEEDSSSEGSSSRKNSLKDKARWQFIIGDLLDSENDIFEQPKEWDSHGSEEPQKAFD
HGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTAS
PASAKAKLGVLSNTSEPGKFPLLGNAGLSGLVEGILDLFSAKAVYMGHPNIDIHTVCVQN
KLSNMSLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ
HWLRKQYVSLYQEDGRYEGPTLAQAVELFGGRRWSTRNPSPGTSAKSAEKPNTLSISNTK
KKKKILMRGESGEVTDDEMATRKARTHKESRSRSGSDPQDVNEQEESEANAIMNPPNPLP
SRRAHSLTTTGPPTLAAGTASPIRPVSSPVLPASNRSPTSAWNSSSGWPGKIKGGMQGFQ
SFMVSDSSMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCDRAGSEAAPLYTNLTIDENI
SGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGVFGV
GILQLNDFLVNCQGEHYTYDEILSIIQKFEPSVSMCHQGLMSFEGFARFLMDKDNFASKN
DESQENVKEMQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGD
DGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTV
FGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQA
QAYNGSNANSPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIP
KRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLN
ASGSSRGKERKSRKSIFGNNPGRMSPGETAPFNKTSGKSSCEGMRQAWEDSAFSVNPTTS
LSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLLF
WLHGIQLVALNYQTDDLSLHLNAAMFEANGGCGYVLKPPVLWDKNCSMYQKFSPLERDLD
SMEPAIYSLTIVSGQNVCPSNSTGSPCIEVDVLGMALDSCHFRTKPIHRNTLNPMWNEQF
LFRVHFEDLVFLRFAVVENNSSVVTAQRIISLKALKRGYRHLQLRNLHNEVLEISSLFIN
SRRMEENSSGNTVLASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTKAKQLLQQ
ILVMDQDTKPIATDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILSSWFPEEGYV
GRIVLKTQQENLEEKSIAQDDKEMLLSSEEDSFFVQVHDVSPEQPRTVIKAPRVSTAQDV
IQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTANRKSSTPKASQRVLLDQECVFQAQSK
WKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKTKQPRGPTSPSQVLASENVQNKE
EKPVGGLPSSDTIDYRQ
NT seq
6894 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcaggttctgttctcagacctgtgagtcagagaaaagtgatc
tctgctcagtcaactgtagatgaaagtaatgataaggtctcgggcatcagtgttccgaag
tctcatcctgtcaggcagagtggggagacttctcataccatctcgcaaccgaccaaactt
acagaagaatcttctggaagcaacgcgccccagattttctcagtagcaagggagaaaata
accagtgacgagaacagtaatgaaaagtgctgggagaaaagcatgccagattctgtgaaa
aaccttaacattaactgcaacagcatattgaaaaaccatcagcacggccctcctcagagc
cagttttatgaaacgtgcaattctatcacagaggaaggtctgtgtttggaaactggaatc
ccttcttcactggaaggaaaggtgttccctggaattcaactggaaatagacacatctccc
atgggcatgagtccattaggaactcagtcggccatcatagagacaagcagggcacaccct
gaaagcaacatggcagtgtttcacttgcgttacgaagttgacagaagaatgtcagacagt
ttctgtcccctgtcagataacttgattttggatgattgtggaaactgtgtactacctgcc
gttggtgaggaacaagagaaaaattacatggcatatacttgcaaactgatggaattgaca
aataactgtgacaataagaataggcagctgcagtgtgatcattgtgaccccttgaatgac
aaatacttgtgctttgaaggctcttgcccaaaggccgatgtggtatgttcaagtgacagc
ttttgcagggaggattttactgacagtccacctgccaagacctttctgagccattttgag
gacttccccgataattgtgaagaggtagaagaagatttgttcaaaaataaaaaggagcgg
tctgcttggttagtgaggagattttgcaaaaatgacaaggaagttaagaaatctgtgttt
actgggacaagggcaattgtgagaactttgccttctggtcacattggactggaggctttg
agttacattgatcagaagaaaaatggtctcttattgcctcctgggagagtcatggaacgg
ctgtcaacaatggtggttaggcaagatggttcccaaggtctgtcagaagcccagtggtat
ccgatctacagtgcagtgagaaggggagaagccacagaacagacaattagatctcttctc
catttcttcgccaagctcccagcctccgagacagcccatgagaggatcagtgtcggtccg
tacttaaagcaatgtgtccgagacacagtgtgtgagtatcgtgccaccttgcaaaggact
tccatatctcagtatatcaccggctctctcctggaagccaccacatctttaggagcaaga
agcagcctcctcaattcttttggaggatccacgggacgaatgatgctgaaagaacgccaa
ccaggcacctctatggccaactccagtgcccttccttcaagttcagctgggatcagcaag
gaactgattgatctgaagcccctcatccagttcccagaggaagtcgccagcatcctgatg
gagcaggagcaaaatatttaccgaagggtcttgccagttgactatcttttcttcttgacc
cggggcttgggcacaacagaacgccagaggtccctgccctgcctcaaagcatccatctca
gcatccattcttacctcccagaagggagagcacaatgccctcgaagatcttgtgatgaga
tttaatgaggtgagctcctgggtgacgtggctgatcctcgcggcgggctccatggaagag
aagcgggaagtcttctcatacttggttcatgtggccaaatgctgctggaacatgggcaac
tacaatgccgtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtgg
cagtttatggaccagtctgatctggagaccatgaggagcctgaaggacgccatggcccag
cacgagtcttcctgcgagtacaggaaggtggtgacccgagcgctgcacatccccggctgc
aaggtggttcccttctgcggggtgtttctgaaagagctctgtgaggtgctggacggagcc
tctggcctcatgaagctttgcccgaggtacaattcgcaggaagaaactctggagtttgta
gccgattatagtggacaagataatttcttacaacgagtgggacagaatggcttaaagaat
tcagagaaggagtccactgtcaacagcatctttcagatcatcaggagctgcagtcgaagt
ctggagacagaggaggaggacagctccagtgaagggagcagctcaaggaaaaattccctg
aaggataaagcccgatggcagtttataatcggagatttgttggattctgaaaatgacatc
tttgagcagcccaaagagtgggactctcatggatcggaggagccacagaaagcctttgac
catgggacagagctcatcccatggtatgtgctgtccatccaagccgatgtgcaccagttc
ctgttgcagggggccacggtcatccactatgatcaggacacgcacctctctgcccgctgc
ttcctccagcttcagcctgacaatagcaccttgacctggataaaacccaccactgcttcc
ccagccagtgctaaagcaaaacttggtgtgctcagtaacacgtctgagcctggcaaattc
ccgttactgggcaatgctggattaagtggcctggtggaggggatcttggatctgttttca
gcaaaggctgtgtacatgggacaccctaacattgatatacacactgtgtgtgttcagaac
aaactgagtaacatgtctctctcagagactggcgtgacactgctctacgggctgcagacc
acggacaatagattactgcactttgtggcgccaaagcacacagctaaaatgctcttcagt
ggattgttggagctcacgagagctgtgaggaagatgaggaagttccctgaccaaagacag
cattggctgcggaaacagtacgtcagcctctaccaggaggatggacgatatgaaggccca
actttggctcaagctgtagagctgtttggtggcagacgatggagtactcgaaaccccagc
cctgggacatcagcaaagagcgctgagaagcccaacaccttgagtataagcaacaccaag
aaaaagaagaaaatccttatgaggggtgagagtggagaggtgacggatgatgagatggcc
acccgcaaggccagaacacacaaagagagccggagccggagtggctctgatcctcaagat
gtcaacgaacaagaagaatcagaggcaaatgccatcatgaaccctcccaaccctctccct
tccagaagagcccactccttgaccacgactgggccccctaccttggctgccgggacagca
tctcccatcaggccagtgtcctctcctgtgctgcctgcttccaacaggagcccaaccagt
gcttggaacagcagcagcggctggccagggaagatcaaaggagggatgcagggctttcag
agcttcatggtttcagacagcagcatgagtttcgtggaatttgttgagctgttcaagtca
ttcagtgtgaggagccgcaaggacctgaaggacctctttgacatctacgccgtaccctgt
gaccgagctggctctgaggcagcccccctctataccaacctgaccattgacgaaaatatc
agcggtcttcagcctgacctagatttgttgaccagaaatgtctcagatttgggattattc
atcaagagtaaacagcagctgtctgacaaccagaggcagatatctgatgccattgctgct
gccagtattgtgacaaatggcaccggggtggagagcacatctctgggtgtgtttggagtt
ggtatcctccagctcaatgacttcctagtgaattgccaaggagaacactatacttatgat
gaaatcctcagcattatccagaagttcgagcctagcgttagtatgtgtcatcaaggccta
atgtcatttgaaggatttgcaaggtttctaatggataaagataattttgcctcgaaaaat
gatgagtcacaggagaacgttaaagaaatgcagctgcccctctcctactattacattgaa
tcttcacacaatacctacctcacgggccatcagctcaaaggagaatcctcagtagaactc
tacagccaggtcctcctgcaaggctgtaggagtgtagagttggactgctgggacggagat
gatggaatgcccatcatttatcatggacacaccctgacaaccaagatccccttcaaggaa
gtggttgaagccatcgatcgcagtgccttcatcaactctgacctacccatcatcatatcg
attgagaaccactgctcattgcctcagcaacgaaaaatggcagaaattttcaagactgtg
tttggagaaaaactggtggctaaattcttatttgagagtgatttctcagatgatcctatg
ctcccctcacctgaccaactcagaaggaaagtgcttctcaaaaataagaaattaaaagcc
catcagacaccggtggatatcttaaagcaaaaggctcatcagctagcatccatgcaagct
caggcttataatggtagcaatgccaactccccacctgctaataatgaggaagaggaagat
gaagaggatgaatatgattatgattatgaatccctctctgatgacaacattctagaagac
agacctgaaaataaatcatgtaatgacaaacttcagtttgagtataatgaagaaatcccc
aagaggataaagaaagcagataactctgcttgcaacaaagggaaggtttatgacatggaa
ctgggagaagaattttatcttcctcagaataaaaaggaaagcagacagattgcaccagag
ctttctgaccttgtcatctattgccaagcagtaaaattcccaggcctgtcaactctaaat
gcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaat
ccgggcagaatgagccccggggagacagcaccatttaacaaaacatctggaaaaagttcc
tgtgaaggaatgcgacaggcctgggaggactctgctttctccgtcaacccaaccacgtcc
ctcagcgctatcattagaactcccaaatgctaccatatctcctcactgaatgaaaatgcc
gccaaacgtctgtgtcgcaggtattctcagaaactcatccagcacaccgcctgccagctg
ctgcggacgtacccggctgccacccgcatcgactcctccaaccccaaccccctcctgttc
tggctccatgggatacagctcgtggcgctcaactaccagacagatgatctctctttacat
ttaaatgccgccatgtttgaggccaatggtggctgcggttatgttctgaaacccccagtt
ctgtgggacaagaactgttccatgtatcagaagttctcccccttggaaagagacctggac
agcatggagcctgccatctattctttaactattgtctctgggcagaacgtgtgcccgagt
aacagcacggggagcccatgtatcgaagtcgatgtcctgggcatggccctggacagctgc
cacttccgcacgaagcccatccaccgcaatactctgaaccccatgtggaacgaacagttt
cttttccgggttcacttcgaagatctcgtatttcttcgttttgctgtcgtggagaacaac
agctcggtggtcactgctcagagaatcatctccctcaaggctctaaagcgaggatatcga
catcttcagctgagaaatctccacaatgaagtcttggaaatctctagtttattcataaac
agcaggaggatggaagaaaattcttccggcaatactgtgctggcctctctgatgtttaat
acggaagaaagaaaatgtttgcagactcacagagtcacagtgcatggcgtcccaggccca
gagccctttactgttttctctataaacggaggcactaaggcaaagcagcttctccaacaa
attctcgttatggatcaagataccaaacctattgccacagattattttttaatggaggaa
aaatatttcatatctaaagagaagaatgaatgtaggaaacagccgttccagagagccatt
ggtccagaagaagagatcgtgcagattttaagcagctggtttccagaagagggctatgtt
ggcaggattgtcttaaaaacccagcaggaaaacctggaagagaagagcattgcacaagat
gacaaggagatgctcctgagctcagaggaggacagcttctttgtccaggtgcatgacgtt
tccccagagcaaccacgcacggtcatcaaggcgccgcgtgtcagcaccgcgcaggatgtc
attcagcagaccttatgcaaagccaaatattcctatagcatcctgagcaaccccaacccg
agtgactatgtgcttttggaagaggtggtgaaagacaccgccaacaggaaatcttccacc
ccaaaggcctcccagcgcgtccttttggatcaggagtgtgtgtttcaagctcaaagcaag
tggaaaggtgcaggaaaattcatccttaagctaaaggaacaggtgcaggcatctcgagaa
gataaaaaaaaaggcatctcttttgcaagcgaactcaagaagctcaccaagactaaacag
ccccgaggacccacatcaccttctcaggtcttggcctcagaaaacgtccaaaacaaggaa
gagaaacctgtgggtggcttgccttccagtgacaccatagactaccgacagtga
DBGET
integrated database retrieval system
