KEGG   Castor canadensis (American beaver): 109685239Help
Entry
109685239         CDS       T04791                                 

Gene name
Hk1
Definition
(RefSeq) hexokinase-1
  KO
K00844  
hexokinase [EC:2.7.1.1]
Organism
ccan  Castor canadensis (American beaver)
Pathway
Glycolysis / Gluconeogenesis
Fructose and mannose metabolism
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Neomycin, kanamycin and gentamicin biosynthesis
Metabolic pathways
Carbon metabolism
HIF-1 signaling pathway
Insulin signaling pathway
Type II diabetes mellitus
Carbohydrate digestion and absorption
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:ccan00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    109685239 (Hk1)
   00051 Fructose and mannose metabolism
    109685239 (Hk1)
   00052 Galactose metabolism
    109685239 (Hk1)
   00500 Starch and sucrose metabolism
    109685239 (Hk1)
   00520 Amino sugar and nucleotide sugar metabolism
    109685239 (Hk1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    109685239 (Hk1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    109685239 (Hk1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    109685239 (Hk1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    109685239 (Hk1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    109685239 (Hk1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    109685239 (Hk1)
Enzymes [BR:ccan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     109685239 (Hk1)
Membrane trafficking [BR:ccan04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    109685239 (Hk1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
UniProt: 
LinkDB All DBs
Position
Unknown
AA seq 916 aa AA seqDB search
MIAAQLLAYYFTELKDDQVKKIDKYLFAMRLSDETLIDIMMRFKREMQNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEAYDTPENIVH
GSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAVLITWTKRFKASGV
EGADVVKLLDKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCISVQHVCTIVTFRSANLVAATLSAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQYARRFHKTLRRLVPDTDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLT
KQMLLEVKRRMREEMETGLRKATNDKAVVKMLPSFVRSTPDGTEHGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCKQTSLDAGILVTWTKGFKATDCVGHDVATLLRDAIKRREEFDLDVVAMVNDTVG
TMMTCAYEEPSCEIGLIVGTGCNACYMEEMKNIEMVEGDQGQMCINMEWGAFGDNGCLDD
IRTEYDRLVDEFSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRG
IFETKFLSQIESDRLALLQVRTILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAA
VVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLREASS
NT seq 2751 nt NT seq  +upstreamnt  +downstreamnt
atgatcgccgcgcagctcctggcctattacttcaccgagctcaaggatgaccaagtcaaa
aagattgacaagtatctgtttgccatgcggctctccgatgaaactctgatagatattatg
atgcgcttcaagagggaaatgcagaatggcctctcccgagattttaatccgacagccacg
gtgaagatgttgccaacctttgtaaggtccattcctgatggttcagaaaagggagatttc
atagccctggatcttggcgggtcttcttttcgaattctgcgggtacaagtgaatcacgag
aagaaccagaatgttcacatggagtcagaggcttatgacaccccagagaatattgttcat
ggcagtggaagccagctctttgatcatgtcgctgagtgcctgggggacttcatggagaaa
aggaagatcaaggacaagaaattgcctgtgggattcacgttttccttcccttgccagcag
tccaaaatagacgaggcagtcctgatcacatggaccaagcggtttaaagccagtggtgtg
gaaggggcagatgtggtcaaactcctggacaaagccatcaagaagcgaggggactatgat
gccaacattgtagctgtggtgaacgacacggtggggaccatgatgacctgtggctatgat
gaccagcactgtgaagtcggactgatcattgggactggcaccaacgcttgctacatggag
gaactgaggcacatcgacctggtggaaggtgacgaggggaggatgtgcatcaacaccgag
tggggggcctttggggatgacgggtccctggaagatatccgcaccgagtttgacagagag
ctggaccgggggtccctcaaccctggaaagcagctgtttgagaagatggtcagcggcatg
tacctgggggagctggtccgcctcatcctggtcaagatggccaaagagggcctcttattt
gaagggcggatcaccccggagctgctcacgagggggaagtttaacaccagtgatgtgtca
gccatagaaaagaataaggaaggcctccacaatgccaaagagatcctgacccgcctggga
gtggaaccatctgatgacgactgtatttcagtccagcatgtatgcaccattgtcacgttt
cgctcggccaacctggtggctgctacactgagtgccatcctgaatcgtcttcgtgataac
aaaggcacgcccaggctgcggaccacggttggtgtggacggctctctttacaagacgcac
ccacagtatgcccggcgtttccacaagaccctgaggcgcctggtgcccgacaccgatgtg
cgcttcctcctctcggagagtggcagtggcaagggggccgctatggtgaccgcggtggcc
taccgtctggctgagcagcatcggcagatagaggagaccctggcccacttccacctcacc
aagcagatgcttttggaggtgaagaggaggatgcgggaggagatggagacagggctgagg
aaggcgacaaacgataaggctgtggtcaagatgctgccttcctttgtccggagcacgcca
gacgggactgagcatggtgacttcttggccctggatcttggaggaacgaatttccgtgtc
ctgctggtgaaaattcgtagtgggaaaaagagaacggtggaaatgcacaacaagatctat
gccattcccattgagatcatgcagggtactggggaagagctttttgaccacatcgtctcc
tgcatctccgacttcctggactacatggggataaaaggcccccgaatgcctttgggcttt
actttctcatttccctgcaagcagacaagtctggatgcgggaatcctggttacctggacc
aagggttttaaggcaactgactgtgtgggtcacgatgtagccaccttactgagagatgca
ataaaaaggagagaggaatttgacctggatgtggtggctatggtcaatgacacagtgggc
actatgatgacctgtgcttatgaggagccctcgtgtgagattggacttatcgtagggacg
ggttgcaatgcctgctacatggaggaaatgaagaacattgagatggtggagggggaccag
ggacaaatgtgcatcaacatggagtggggtgcctttggagacaatgggtgtctggatgat
atcagaactgaatatgacagattggtggatgaattctctctaaacgctgggaagcaaagg
tatgagaagatgatcagtggtatgtacctgggtgaaatcgtccgcaacattctcatcgac
ttcaccaaaaagggattcctcttccgagggcagatctctgaaccactcaagacccggggc
atctttgagaccaagtttctctctcagattgagagtgaccgattagcgctgctccaggtc
cggaccatcctccagcagttgggtttgaacagcacatgtgacgacagcatcctggtcaag
actgtgtgtggggtggtgtccaagagggctgcacagctgtgtggcgcaggcatggctgca
gtggtggacaagatccgagagaacagagggctggaccatctgaatgtgaccgtgggagtg
gacgggacgctctacaagcttcatccacacttctccagaatcatgcaccaaaccgtgaag
gagctgtcaccaaagtgtaacgtgtcctttctcctgtctgaggacggtagtggcaagggg
gctgccctcatcacagccgtgggtgtgcggctccgagaagcgagcagttaa

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