Castor canadensis (American beaver): 109696750
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Entry
109696750 CDS
T04791
Symbol
Irs1
Name
(RefSeq) LOW QUALITY PROTEIN: insulin receptor substrate 1
KO
K16172
insulin receptor substrate 1
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan04022
cGMP-PKG signaling pathway
ccan04068
FoxO signaling pathway
ccan04140
Autophagy - animal
ccan04150
mTOR signaling pathway
ccan04151
PI3K-Akt signaling pathway
ccan04152
AMPK signaling pathway
ccan04211
Longevity regulating pathway
ccan04213
Longevity regulating pathway - multiple species
ccan04722
Neurotrophin signaling pathway
ccan04910
Insulin signaling pathway
ccan04920
Adipocytokine signaling pathway
ccan04923
Regulation of lipolysis in adipocytes
ccan04930
Type II diabetes mellitus
ccan04931
Insulin resistance
ccan04932
Non-alcoholic fatty liver disease
ccan04935
Growth hormone synthesis, secretion and action
ccan04960
Aldosterone-regulated sodium reabsorption
ccan05010
Alzheimer disease
ccan05206
MicroRNAs in cancer
ccan05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
109696750 (Irs1)
04022 cGMP-PKG signaling pathway
109696750 (Irs1)
04151 PI3K-Akt signaling pathway
109696750 (Irs1)
04152 AMPK signaling pathway
109696750 (Irs1)
04150 mTOR signaling pathway
109696750 (Irs1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
109696750 (Irs1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
109696750 (Irs1)
04923 Regulation of lipolysis in adipocytes
109696750 (Irs1)
04920 Adipocytokine signaling pathway
109696750 (Irs1)
04935 Growth hormone synthesis, secretion and action
109696750 (Irs1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
109696750 (Irs1)
09156 Nervous system
04722 Neurotrophin signaling pathway
109696750 (Irs1)
09149 Aging
04211 Longevity regulating pathway
109696750 (Irs1)
04213 Longevity regulating pathway - multiple species
109696750 (Irs1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
109696750 (Irs1)
09164 Neurodegenerative disease
05010 Alzheimer disease
109696750 (Irs1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
109696750 (Irs1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
109696750 (Irs1)
04932 Non-alcoholic fatty liver disease
109696750 (Irs1)
04931 Insulin resistance
109696750 (Irs1)
BRITE hierarchy
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Ortholog
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Motif
Pfam:
IRS
PH
PH_11
Motif
Other DBs
NCBI-GeneID:
109696750
NCBI-ProteinID:
XP_020035521
UniProt:
A0A8B7VU99
LinkDB
All DBs
Position
Unknown
AA seq
1241 aa
AA seq
DB search
MASPPDTDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP
KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKSH
HDGAAAPRAGGCGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI
GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV
DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT
RRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHTYRHR
GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP
SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMSGKGASTLTAPN
GHYILSRGGNGHRYIPGVGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTISHQKTP
SQSSVTSIEEYTEMMPAYPPGGGSGGRLPGYRHSAFVPTHSYPEEGLEMHPLERGGSHHR
PDTSTLHTDDGYMPMSPGVAPVPSSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN
GYMMMSPSGSCSPDIGGGSSSSSSISAAPSGSSYGKLWTNGVGSHPSHALSHTKPPVESG
GGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGSEDPQLKPVLSYYSLPRSFKHTQRPGEPE
EGARHQHLRVSSSSGRLLYTATAEDSSSSTSSDSLGGGYCGARSEPGLPHPHHHVLQAHL
PRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQPLLHPPEPKSPGEYVNIEFG
SDQPGYLAGPMPSHSSPSVRCPPQLQPVPREEASGTEEYMNMDLGPGRRATWQESGAAEM
GRVGPAPPGAASVCRPTRAVPSGRGDYMTMQMGCSRQSYVDTSPVAPVSYADMRTGIAAG
EVSLPRAAAAAPSSSSAASASPTAPQGAAELPARSSLLGGSQGPGGMSAFTRVNLSPNRN
QSAKVIRADPQGCRRRHSSETFSSTPTATRVGNMVPFGAGATMGGSGGGGSSSSEDVKRH
SSASFDNVWLRPGXLGGAPKEMAQVCGAAGGLENGLNYIDLDLVKDFKQRPQECPPQQQP
PPPPPPHQSLGSSESSSTSRSSEDLSAYASISFQKKPEDLQ
NT seq
3726 nt
NT seq
+upstream
nt +downstream
nt
atggcgagccccccggataccgatggcttttccgatgtgcgcaaggtgggctacctgcgc
aaacccaagagtatgcacaagcgcttcttcgtgctgcgggcggccagcgaggctgggggt
ccggcgcgcctggagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc
aaacgctcgatcccccttgagagctgcttcaacatcaacaagcgggctgactccaagaac
aagcacctggtggctctctacacccgggacgagcactttgccattgcggcggatagcgag
gccgagcaagacagctggtaccaggctctcctgcagctgcacaaccgtgccaaaagccac
cacgacggggccgcagccccaagagctggaggctgtgggggcagctgcagcggcagttct
ggcctgggcgaggctggggaggacttgagctatggagacgtgcccccaggacctgcgttc
aaggaggtctggcaggtgattctgaaacccaagggcctgggtcagacaaagaacctgatt
ggcatctaccgcctctgcctgaccagtaagaccatcagctttgtgaagctgaactcagag
gcagccgccgtggtgctgcagctgatgaacatcagacgctgtggccattcagagaacttc
ttcttcatcgaggtgggccgttccgccgtgacagggcccggggagttctggatgcaggtg
gatgactcggtggtggcccagaacatgcatgagactatcctggaggccatgcgggccatg
agcgatgagtttcgtcctcgtagcaaaagccagtcctcatccaactgctccaaccccatc
agtgtccccctgcgcaggcaccatctcaacaaccctccacccagtcaggtggggctgacc
cgcagatcacgcactgagagcatcactgccacctccccagccagcatggtgggtgggaag
ccaggttccttccgtgtgcgtgcctccagcgatggcgaaggcaccatgtcccgcccagcc
tcagtggatggcagccctgtgagtcctagcaccaacagaacccacacctaccggcatcgg
ggcagctcaaggctgcacccccctctcaaccacagccgctccatccccatgccttcttct
cgctgctcgccttcagctaccagcccagtcagtctgtcgtccagtagcaccagtggccat
ggctccacctcggactgtctcttcccaaggcggtctagtgcttctgtgtctggttccccc
agcgatggcggtttcatctcttcggatgagtatggttctagtccctgcgatttccgaagt
tctttccgcagtgtcactcctgattccctgggccacaccccaccagcccgtggagaggaa
gagctgagcaactatatctgcatgagtggcaagggggcctccacactgactgctcccaat
ggtcactacattttgtctcggggtggcaatggccaccgttatatcccaggagttggcttg
ggtacaagcccagccttggctggggatgaagcagccagtgctgcagatctggataatcgg
ttccggaagagaactcattctgctggcacatcccctactatttcccaccagaagaccccc
tcacagtcctcagtgacttccattgaggaatatacagagatgatgcctgcctacccacca
ggaggtggcagtggaggccgactgcctggctaccggcactccgcctttgtgcccacgcac
tcctaccccgaagagggcctagagatgcaccccttggagcgtggtggcagccaccaccgt
ccagatacctccaccctccacactgacgatggctacatgcccatgtccccaggggtggcc
ccagtgcccagcagccgaaagggcagtggggactatatgcccatgagtcccaagagcgta
tctgccccacagcagattatcaaccctatcagacgccatcctcagagagtggaccccaat
ggctacatgatgatgtcccccagtggaagctgctcccctgacattggaggcgggtccagc
agcagcagcagcatcagtgctgccccttctgggagcagctatgggaagctatggacaaat
ggggtagggagccacccttctcatgccctatctcacaccaaaccccctgtggagagtggt
ggtggcaagctcttgccttgcacaggcgactacatgaacatgtcaccagtgggggactcc
aataccagcagcccttctgactgctattacggctctgaagatccccagctcaagccagtc
ctctcctactactcattgccaaggtcctttaagcacacccagcgccctggggagccagag
gagggtgcccggcaccagcacctccgcgtttcctctagctctggtcgccttctctacact
gcaacagcagaagattcttcttcttccaccagcagtgacagcctgggcgggggttactgt
ggggctagatcggagcctggccttccacatcctcatcatcatgtcctgcaggcccatctg
cctcgaaaggtggacacagctgcacagaccaatagccgcctggctcggcccacgaggcta
tccctgggggatcccaaggccagcactttacctcgggcaagagagcagcagcagcagcag
cccctactccacccaccggagcccaagagcccaggggagtatgtgaatattgaatttggt
agtgaccagcctggctacttagctggccccatgccttcccacagctccccttctgtccga
tgtccaccccagctccagccagttcccagagaggaagcgtctggcactgaggagtacatg
aacatggacctgggaccaggacggagggcaacctggcaggagagtggtgcagctgagatg
ggcagagtgggccccgcacctccaggggctgctagtgtttgcaggcccactcgggcagtg
cccagcggccggggtgactacatgaccatgcagatgggttgttcccgtcagagctatgtg
gacacctccccagttgcccctgtgagctacgctgacatgcggacaggcattgctgcaggg
gaggtgagcctgcctagagccgcagcggctgccccctcttcatcgtcagcagcatctgct
tcccccactgcacctcaaggagcagctgagctgcctgcccgctcctccctgctggggggt
tcgcagggacctgggggcatgagcgcctttaccagggtgaacctgagtcccaaccgcaac
cagagtgccaaagtgatccgggcagacccacaagggtgccggaggaggcatagctccgag
accttctcctcaacacctactgccacccgggtgggcaacatggtgcccttcggagcaggg
gctacaatggggggcagtggtggtggcggcagcagcagtagtgaagatgtgaaacgccac
agctctgcttcctttgataatgtgtggctgagacctgggnagctagggggagcccctaaa
gagatggctcaagtgtgtggggctgctgggggtttggagaatggtcttaactacatagac
ctggatttggtcaaggacttcaaacagcgcccccaggagtgcccccctcaacaacagcca
cccccacccccgccccctcatcagtccctgggcagcagtgagagcagctccaccagccgc
tccagtgaggatttaagcgcctatgctagcatcagtttccagaagaagccagaagacctt
cagtag
DBGET
integrated database retrieval system
