Canis lupus familiaris (dog): 484137
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Entry
484137 CDS
T01007
Symbol
PTCH1
Name
(RefSeq) protein patched homolog 1 isoform X1
KO
K06225
patched 1
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04024
cAMP signaling pathway
cfa04340
Hedgehog signaling pathway
cfa04360
Axon guidance
cfa05200
Pathways in cancer
cfa05205
Proteoglycans in cancer
cfa05217
Basal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
484137 (PTCH1)
04024 cAMP signaling pathway
484137 (PTCH1)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
484137 (PTCH1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
484137 (PTCH1)
05205 Proteoglycans in cancer
484137 (PTCH1)
09162 Cancer: specific types
05217 Basal cell carcinoma
484137 (PTCH1)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Patched
Sterol-sensing
Motif
Other DBs
NCBI-GeneID:
484137
NCBI-ProteinID:
XP_003638919
Ensembl:
ENSCAFG00000001246
VGNC:
49951
LinkDB
All DBs
Position
1:72001309..72071860
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AA seq
1450 aa
AA seq
DB search
MASAGNAAEPQDRGGGGGSGAPGRPAGGGRRRRAGGLRRSAALDRDYLHRPSYCDAAFAL
EQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLE
TNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALRQHLDSA
LQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQ
SGTAYLLGKPPLQWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADP
DCPATAPNKNATKPLDVALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQT
MFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAPNSTQKVLSF
TTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVA
AGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLK
RTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYR
REDRRLDIFCCFTSPCVSRVIQVEPQAYTETHDNTRYSPPPPYSSHSFTHETQITMQSTV
QLRTEYDPHTHVYYTTAEPRSEISVQPVTMTQDTLSCQSPESTSSTRDLLSQFSDSSLHC
LEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVP
RETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHKSFSNVKYVMLEENKQLPK
MWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQL
TKQRLVDAHGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLR
IPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRSICNNYTSLGLSSYPNGYPFLFWEQYI
GLRHWLLLSVSVVLACTFLVCAVFLLNPWTAGIIVTVLALMTVELFGMMGLIGIKLSAVP
VVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAG
SEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPP
SVVRFAVPPSHANNGSDSSDSEYSSQTTVSGISEELRHYEAQQGTRGPAHQVIVEATENP
VFARSTVVHPEARHHPPSNPRQQPPLDSEPLPPGRPGQQPRREPPREGLRPPPYRPRRDA
FEISTDGHPGPGSRDRAGPRGARSNNPRHPVFTAMGSSAPSYCQPITTVTASASVTVAVH
PPPAPGPGSAWNPRGGLCPGYGDCPETDHRLFEDPHVPFNVRCERRDSKVEVIELQDVEC
EERPRGGSSN
NT seq
4353 nt
NT seq
+upstream
nt +downstream
nt
atggcctcggctggtaacgccgcggagccccaggaccgcggcggtggcggcggcagcggg
gcccccggccggccggccggcggcgggagacgcagacgggccggggggctgcgccgcagc
gccgcgctggaccgggactatctgcaccggcccagctactgcgacgccgccttcgctctg
gagcagatttccaaggggaaagctactggccggaaagcgccgctgtggctgagagcgaag
tttcagagactcttatttaaactgggttgttacattcaaaaaaactgcggcaagttcttg
gttgtgggcctcctcatatttggggccttcgctgtgggattaaaggcagctaatctcgag
accaacgtggaggagctgtgggtggaagttggtggacgagtaagtcgtgaattaaattat
actcgccagaagattggagaagaggctatgtttaatcctcaactcatgattcagaccccg
aaagaagaaggtgctaacgtcctgaccacagaagctctccgacaacacctggactcagcg
ctccaggccagccgggtccatgtgtatatgtataacaggcagtggaaattggaacatttg
tgttacaaatctggagaacttatcacagaaacaggttacatggatcagataatcgaatat
ctttacccttgtttaattattacacctttggactgcttctgggaaggggcaaagttacaa
tctgggacagcatacctactaggtaagcctcctttgcagtggacaaactttgaccctttg
gaattcctggaagagttaaagaaaataaactatcaagtggacagctgggaggaaatgctg
aataaagctgaagttggtcatggttacatggaccggccctgcctcaacccggctgatccg
gactgccccgccacagcccccaacaaaaatgcaaccaaacctcttgatgtggcccttgtt
ttgaatggtggatgtcatggattatccagaaagtacatgcactggcaggaggaactgatt
gtgggtggcacagtcaagaacagcaccgggaagcttgtcagcgcccacgccctgcaaacc
atgtttcagttaatgactcccaagcaaatgtacgaacacttcaaggggtatgagtatgtc
tcacacattaactggaatgaggacaaggcagcagccatcctggaggcttggcagaggaca
tatgtggaggtggttcatcaaagtgtcgctccaaactccactcagaaagtgctttccttc
accaccacaaccctggatgacatcctgaagtccttctctgatgtcagcgtcatccgagtg
gctagtggctacctcctgatgcttgcctatgcctgtttaaccatgctgcgctgggattgc
tccaagtcccagggtgccgtggggctggctggcgtcctgttggttgcactgtcagtggct
gcaggattgggcctgtgctcattgatcgggatttcctttaacgctgcaacaactcaggtt
ttgccatttctcgctcttggtgttggtgtggatgatgttttccttctggcacatgcattt
agtgaaacaggacagaataaaagaatcccttttgaggataggactggggagtgcctgaag
cgcacaggagccagtgtggcgctcacctccatcagcaatgtcacagccttcttcatggct
gctctgatccctattcccgctctgcgagccttctcccttcaggcggctgtagtagtggta
ttcaattttgctatggttctgctcatttttcctgcaattctcagcatggatttgtatcga
cgtgaggacaggagattggatattttctgctgttttacaagcccctgcgtcagcagagtg
attcaggttgaacctcaggcctacacggagactcacgataacactcgctacagtcccccg
cccccctacagcagccacagcttcacccacgaaacccagatcaccatgcagtccacagta
cagctccgcacagagtatgacccccacacgcacgtgtactacaccaccgccgagccacgc
tctgagatctccgtgcagcccgtcaccatgacccaggataccctcagctgccagagccct
gagagcaccagctccacgagggacctgctctcccagttctctgactccagcctccactgc
cttgagcccccttgcaccaagtggacactttcatcttttgccgagaaacactatgctcct
ttcctcttgaaaccaaaagccaaggtcgtggtcatcttccttttcctgggcttgctgggg
gtcagcctttatgggaccacccgagtgcgcgatgggctggacctcacagacattgtgccc
cgggaaaccagagaatatgattttattgctgcacagttcaaatacttctctttctacaac
atgtatatagtcacccagaaagcagactacccaaatatccagcacttactttacgacctt
cacaagagtttcagcaatgtgaagtatgtcatgttggaagaaaataaacagcttcccaaa
atgtggctgcattacttccgagactggttacaaggacttcaggacgcatttgacagtgac
tgggaaactgggaaaatcatgccaaacaattacaaaaatggatcagatgatggggtcctt
gcctacaaactcctggtgcagaccggcagccgcgataaacccatcgacatcagtcagttg
accaagcagcgcctggtggatgcacatggcatcatcaaccccagtgcattctacatctac
ctgactgcctgggtgagcaatgaccctgtggcttatgccgcctcccaggccaacatccgg
cctcaccgtcctgagtgggtgcatgacaaagctgactacatgcccgaaaccaggctcaga
atcccagcagcagagcccatcgaatacgctcagttccctttctacctcaatggcttgcgg
gacacatctgacttcgtggaagctattgaaaaggtccgaagcatctgcaacaactacacc
agcctggggctgtccagctaccccaacggctaccccttcctcttctgggagcagtacatt
ggcctccgccactggcttctgttgtctgtcagcgtggtgctggcctgcacgttcctcgta
tgcgccgtcttcctcctgaacccctggacggccgggatcattgtgacggtgctggctttg
atgacagtcgagctctttggcatgatgggcctcattggaatcaagctgagtgctgtgcca
gtggtcatcctgatcgcttctgtcggcataggagtggagttcaccgttcacgttgctctg
gctttcctgacagccattggtgataagaaccgcagagccgtgctggcgctggagcacatg
ttcgcgcccgtcctggatggcgccgtgtccactctgctgggagtgctgatgctggcgggc
tcggagtttgatttcattgtcaggtatttctttgctgttctggcgatcctaacaatcctg
ggtgttctcaacgggctggttttgctgccagtccttctgtccttcttcggaccgtatcct
gaggtatctccagccaatgggctgaaccgactgcccaccccttcccctgagccacccccc
agtgtggtccggtttgccgtgccacccagccatgcaaacaatgggtctgattcctctgac
tcggagtacagttctcagactacagtgtcgggcatcagtgaagagcttcggcactacgag
gcccagcagggcaccaggggccctgcccaccaggtgatcgtggaagccacagaaaacccc
gtctttgcccgctccactgtggtccatcccgaagcgagacatcacccaccctcaaaccct
cgacagcagccccccctggactcagagccccttcctcctgggcgaccaggccagcagccc
cggagggaaccccccagagaaggcttgcggccgcccccctacagaccgcgcagagacgct
tttgaaatttctactgacgggcatcctggccctggcagtagggaccgtgcgggcccccgg
ggagcccgttctaacaacccccggcacccagtgttcactgccatgggcagctccgcgccc
agctactgccagcccatcaccactgtgacggcctcggcgtccgtgactgttgctgtgcac
cccccgcctgcgcctgggcctggctctgcttggaaccccagaggaggactctgtccgggc
tacggggactgcccggagactgaccacaggctatttgaggacccccacgtgccttttaac
gtccggtgcgagaggagggattccaaggtggaagtcatagagctgcaggatgtggaatgt
gaggagagaccccggggcggtagctccaactga
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integrated database retrieval system
