Capra hircus (goat): 102172767 Help Entry 102172767         CDS       T02910                                  Symbol EGFR Name (RefSeq) epidermal growth factor receptor   KO K04361   epidermal growth factor receptor [EC:2.7.10.1] Organism chx  Capra hircus (goat) Pathway chx01521   EGFR tyrosine kinase inhibitor resistance chx01522   Endocrine resistance chx04010   MAPK signaling pathway chx04012   ErbB signaling pathway chx04014   Ras signaling pathway chx04015   Rap1 signaling pathway chx04020   Calcium signaling pathway chx04066   HIF-1 signaling pathway chx04068   FoxO signaling pathway chx04072   Phospholipase D signaling pathway chx04144   Endocytosis chx04151   PI3K-Akt signaling pathway chx04510   Focal adhesion chx04520   Adherens junction chx04540   Gap junction chx04630   JAK-STAT signaling pathway chx04810   Regulation of actin cytoskeleton chx04912   GnRH signaling pathway chx04915   Estrogen signaling pathway chx04921   Oxytocin signaling pathway chx04926   Relaxin signaling pathway chx04928   Parathyroid hormone synthesis, secretion and action chx04934   Cushing syndrome chx05160   Hepatitis C chx05163   Human cytomegalovirus infection chx05165   Human papillomavirus infection chx05171   Coronavirus disease - COVID-19 chx05200   Pathways in cancer chx05205   Proteoglycans in cancer chx05206   MicroRNAs in cancer chx05207   Chemical carcinogenesis - receptor activation chx05208   Chemical carcinogenesis - reactive oxygen species chx05210   Colorectal cancer chx05212   Pancreatic cancer chx05213   Endometrial cancer chx05214   Glioma chx05215   Prostate cancer chx05218   Melanoma chx05219   Bladder cancer chx05223   Non-small cell lung cancer chx05224   Breast cancer chx05225   Hepatocellular carcinoma chx05226   Gastric cancer chx05230   Central carbon metabolism in cancer chx05231   Choline metabolism in cancer chx05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:chx00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102172767 (EGFR)    04012 ErbB signaling pathway     102172767 (EGFR)    04014 Ras signaling pathway     102172767 (EGFR)    04015 Rap1 signaling pathway     102172767 (EGFR)    04630 JAK-STAT signaling pathway     102172767 (EGFR)    04066 HIF-1 signaling pathway     102172767 (EGFR)    04068 FoxO signaling pathway     102172767 (EGFR)    04020 Calcium signaling pathway     102172767 (EGFR)    04072 Phospholipase D signaling pathway     102172767 (EGFR)    04151 PI3K-Akt signaling pathway     102172767 (EGFR)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     102172767 (EGFR)   09144 Cellular community - eukaryotes    04510 Focal adhesion     102172767 (EGFR)    04520 Adherens junction     102172767 (EGFR)    04540 Gap junction     102172767 (EGFR)   09142 Cell motility    04810 Regulation of actin cytoskeleton     102172767 (EGFR)  09150 Organismal Systems   09152 Endocrine system    04912 GnRH signaling pathway     102172767 (EGFR)    04915 Estrogen signaling pathway     102172767 (EGFR)    04921 Oxytocin signaling pathway     102172767 (EGFR)    04926 Relaxin signaling pathway     102172767 (EGFR)    04928 Parathyroid hormone synthesis, secretion and action     102172767 (EGFR)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102172767 (EGFR)    05206 MicroRNAs in cancer     102172767 (EGFR)    05205 Proteoglycans in cancer     102172767 (EGFR)    05207 Chemical carcinogenesis - receptor activation     102172767 (EGFR)    05208 Chemical carcinogenesis - reactive oxygen species     102172767 (EGFR)    05230 Central carbon metabolism in cancer     102172767 (EGFR)    05231 Choline metabolism in cancer     102172767 (EGFR)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102172767 (EGFR)   09162 Cancer: specific types    05210 Colorectal cancer     102172767 (EGFR)    05212 Pancreatic cancer     102172767 (EGFR)    05225 Hepatocellular carcinoma     102172767 (EGFR)    05226 Gastric cancer     102172767 (EGFR)    05214 Glioma     102172767 (EGFR)    05218 Melanoma     102172767 (EGFR)    05219 Bladder cancer     102172767 (EGFR)    05215 Prostate cancer     102172767 (EGFR)    05213 Endometrial cancer     102172767 (EGFR)    05224 Breast cancer     102172767 (EGFR)    05223 Non-small cell lung cancer     102172767 (EGFR)   09172 Infectious disease: viral    05160 Hepatitis C     102172767 (EGFR)    05171 Coronavirus disease - COVID-19     102172767 (EGFR)    05163 Human cytomegalovirus infection     102172767 (EGFR)    05165 Human papillomavirus infection     102172767 (EGFR)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102172767 (EGFR)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102172767 (EGFR)    01522 Endocrine resistance     102172767 (EGFR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:chx01001]     102172767 (EGFR)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:chx04147]     102172767 (EGFR) Enzymes [BR:chx01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      102172767 (EGFR) Protein kinases [BR:chx01001]  Receptor tyrosine kinases (RTK)   EGFR family [OT]    102172767 (EGFR) Exosome [BR:chx04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    102172767 (EGFR)   Exosomal proteins of pancreatic cancer cells    102172767 (EGFR)   Exosomal proteins of bladder cancer cells    102172767 (EGFR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Borrelia_P83 Kinase-like Kdo ABC1 Haspin_kinase Motif Other DBs NCBI-GeneID:  102172767 NCBI-ProteinID:  XP_017922533 EnsemblRapid:  ENSCHIG00000020547 UniProt:  A0A452FEC6 LinkDB All DBs Position 22:complement(769419..982124) Genome browser AA seq 1208 aa AA seqDB search MRLSRAGRAALLVLLAAHFQASLALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEV VLGNLEITYMQSGYNLSFLKTIQEVAGYVLIALNTVEKIPLENLQIIRGNVLYENTHALA VLSNYGANKTGLRELPLRNLQEILQGAVRFSNNPVLCNMETIQWRDIINTDFLSNVTGDF QNQQGNCSKCDPACLNRSCWGAGEENCQKLTKIICAQQCSGRCRGRSPSDCCHNQCAAGC TGPRESDCLVCRRFRDEATCKDTCPPLMLYDPTTYEMKVNPLGKYSFGATCVKKCPRNYV VTDHGSCVRACSSDSQEVEEDGVRKCKKCDGPCAKVCNGIGIGEFKDTLSINATNIKHFR NCTSISGDLHILPVAFRGDSFTRTAPLDPKELDILKTVKEITGFLLIQAWPENRTDLHAF ENLEIIRGRTKQHGQFSLAVVGLDITSLGLRSLKEISDGDVIISGNRNLCYANTIHWKKL FGTSTQKTKILNNRSDKECKATGHICHPLCSSEGCWGPGPKYCMSCQNFSRGKECVGKCN ILEGEPREFVENSECVQCHPECLPQAMNVTCTGRGPGSCVKCAHYIDGPHCVKACPAGVA GENGTLVWKFADASHVCHLCHPNCTYGCIGPGLEGCAASGPKIPSIATGIVGGLLLVLVL ALSVGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKVKVLGS GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAA RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY GVTVWELMTFGSKPYDGIPASEISTVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK FRELILEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLVPQ QGFFHSPTTSRTPLLSSLSASSNTPTVTCVDRSGSYPLKEESFLQRYSSDPTGALTEDSM DDAFLPVPEYVNQSVPKRPAGSVQNPVYHNQPLYPAPGRDPQYQNSRSNAVDNPEYLNTT HPACINGVLDGPALWAQKGSHQISLDNPDYQQAFFPKEAKSNGIFKGPAAENAEYLRAAP AGSDFTGA NT seq 3627 nt NT seq  +upstreamnt  +downstreamnt atgcgactctcgcgggcgggccgcgcggcgctcctggtgctgctggccgcgcacttccag gcgagtctagcgctggaggagaagaaagtttgccaagggacaagtaacaagctcacccag ttgggcacttttgaagaccactttctgagcctccagaggatgttcaacaactgtgaggtg gtccttgggaatttggaaattacctacatgcagagtggttacaacctttcttttctcaag accatccaggaggttgccggctatgtactcattgccctcaacacagtggagaagattcca ttggaaaacctgcagatcatccgaggaaatgtgctttatgaaaacacccatgccttagcc gtcttatccaactatggagcaaacaaaaccggactgagggagctgcccttgagaaactta caggaaattctgcaaggtgccgtgcgattcagtaacaaccctgtcctctgcaacatggag accatccagtggcgggacatcatcaacactgattttctaagtaacgtgacaggggacttt cagaaccagcagggcaactgctcgaagtgtgatccagcctgtctcaacagaagctgctgg ggtgctggggaggagaactgccagaaattgaccaaaatcatctgtgcccagcagtgttcc gggcgctgccgcggcaggtcccccagtgactgctgccacaaccagtgtgccgctggctgc acggggccacgggagagcgactgcctggtctgccgcaggttccgtgatgaagccacctgc aaggacacatgtccaccgctcatgctctatgaccctaccacctacgaaatgaaggtcaac ccgctggggaaatacagctttggcgccacctgtgtcaagaagtgtccccgtaactacgtg gtgacagaccacggctcgtgcgtccgcgcctgcagctctgacagccaggaggtagaggaa gatggtgtccgcaagtgcaaaaagtgtgacgggccttgtgccaaagtttgtaacggaata ggaatcggtgagtttaaagacacactttccataaatgctacaaacattaaacacttcaga aactgcacatccatcagtggagatcttcatatcctgccagtagcatttaggggggactcc ttcacacgtactgcacctctggacccgaaagaactggacattctaaaaactgtaaaagaa ataacagggtttttgctgattcaggcctggcccgaaaacaggactgacctccatgcgttt gagaacctggaaatcatacgtggcagaacgaagcaacacggccagttttctcttgcggtt gtcggcctggatataacatccttgggattacgctccctcaaggagataagtgatggcgat gtgataatttcaggaaatcgaaacttgtgctatgcaaatacgatacactggaaaaaactt tttgggacctcaactcagaaaaccaaaattttaaacaacaggagtgataaagagtgcaag gccacgggccatatctgtcacccactgtgctcatcagagggctgctggggacctggaccc aaatactgcatgtcctgccagaacttcagtcgtggcaaggagtgtgtgggaaagtgcaac attctagagggagagcccagggagttcgtggagaattccgagtgtgtgcagtgccatcca gaatgcctgccccaggccatgaatgtgacctgcactggacgcggaccaggcagctgtgtg aagtgtgcccactacatcgatggccctcactgcgtcaaggcctgccctgctggagtcgcg ggagagaacggcaccctggtctggaagtttgcagatgccagtcacgtgtgtcacctgtgc caccccaactgcacctacggctgtatagggccaggtctcgaaggctgtgcagcaagtggg cccaagatcccgtccattgccacgggcatcgtgggcggcctgctgctggtgttggtgctc gccctgagcgtcggcctcttcatgcgcaggcgccacatcgtgcgcaagcgcacactgcgc cggctgctgcaagagcgtgagctcgtggagcctctgacgcccagcggagaagctcctaac caagctctcttgaggatcttaaaggagacggaattcaaaaaagtcaaggtgttgggctca ggagcatttggcaccgtgtacaagggactctggatcccagaaggcgagaaggttaaaatt cctgtagctatcaaggaattaagagaagccacatctcccaaagccaacaaggagattctt gatgaggcctacgtgatggccagtgtggacaacccacatgtgtgccgcctcctgggcatc tgcctgacctccacagtgcagctcatcacacagctcatgcccttcggctgcctgctggac tacgtccgtgagcacaaagacaacatcggctcccagtacctgctcaactggtgtgtgcag atcgcaaagggcatgaattacctggaagaccggcgcttggtgcacagggacctggcagcc aggaacgtgctggtgaagacgccgcagcacgtgaagatcacagacttcgggctggccaag ctgctgggtgccgaggagaaggagtatcacgcggaaggaggcaaggtccctatcaaatgg atggctttggaatcaattttacaccgaatttatacccatcagagtgatgtctggagctac ggagtcactgtttgggagttgatgacctttggatccaagccttatgatggaatccctgcg agtgagatctcgactgtcctggagaaaggagagcgcctcccacagccacccatctgcacc atcgacgtctacatgatcatggtcaagtgctggatgatagatgcagacagtcgcccaaag ttccgtgagttgatccttgaattctccaagatggcccgagacccacagcgctaccttgtc atccagggggacgagagaatgcatttgccaagccctacggactccaacttttaccgcgcc ctgatggatgaggaggacatggaggacgttgtggatgctgatgagtacctcgtcccccag cagggcttcttccacagccccaccacctctcggacacccctcctcagctccctgagtgcc tccagcaacactcccactgtgacttgcgttgatagaagtgggagctaccctctcaaggaa gaaagcttcctgcagcgctacagttcagaccccactggtgccctcaccgaggacagcatg gacgacgctttcctcccagtacctgaatatgtaaaccaatctgttcccaaaagacctgca ggctctgtccagaaccctgtctatcacaatcagcctctatatccagctcctggcagagac cctcagtaccaaaattcacgcagcaacgccgtggacaaccctgagtatctcaacaccacc catcctgcctgtatcaatggtgtactcgacggccctgccctctgggctcagaagggcagt caccaaattagcctagacaaccctgactaccagcaggccttctttcccaaggaagccaag tcgaatggcatctttaagggacctgcagctgaaaatgcagaatacctgcgggcagcacca gcaggcagtgactttactggggcctga

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