Callithrix jacchus (white-tufted-ear marmoset): 100412740
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Entry
100412740 CDS
T03264
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X3
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
cjc
Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc05012
Parkinson disease
cjc05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
cjc00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
100412740 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
100412740 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cjc01001
]
100412740 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cjc04131
]
100412740 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
cjc04147
]
100412740 (LRRK2)
Enzymes [BR:
cjc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100412740 (LRRK2)
Protein kinases [BR:
cjc01001
]
Serine/threonine kinases: TKL group
LRRK family
100412740 (LRRK2)
Membrane trafficking [BR:
cjc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
100412740 (LRRK2)
Exosome [BR:
cjc04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
100412740 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
COR
LRR_4
Ras
LRR_9
Arf
Ank_2
GTP_EFTU
T2SSE
nSTAND3
G-alpha
LRR_6
ABC_tran
AAA_22
PduV-EutP
AAA_16
AAA_7
Kdo
MobB
MMR_HSR1
SRPRB
TrwB_AAD_bind
cobW
AAA_29
FtsK_SpoIIIE
AAA_23
Septin
NACHT
TniB
ResIII
TsaE
WD40_like
SRP54
Motif
Other DBs
NCBI-GeneID:
100412740
NCBI-ProteinID:
XP_002752413
Ensembl:
ENSCJAG00000017840
LinkDB
All DBs
Position
9:complement(31786235..31939914)
Genome browser
AA seq
2527 aa
AA seq
DB search
MASGSSQVCEEDEETLKKLIVRLNNVQEGKQIETLVQILEDLLVFTYSEHASKLFQGKNI
HVPLLIVLDSYMRVASVQQVGWSLLCKLIEICPGTMQSLMGPQDVGNDWEFLGVHQLILK
MLAVHNASVNLSMIGLKTLDLLLTSGKITLLILDEESDIFLLIFDALHSFPTNDEVQKLG
CKALHVLFERVSEEQLTEFVENKDYMILLSALKNFKEEEEIVLHVLHCLHSLAIPCNNVE
VLMSGNVRCYNIVVEAMKAFPFSEKIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVKAVQ
QYPENATLQISALSCLALLTETIFLNQDLEEKNENQENDDEGEEDKLFWLEACYKALTWH
RKNKHVQEAACWALNNLLMYQNSLHEKIGDEEGHFPAHREVMLSMLMHSSSKEVFQASAN
ALSTLLEQNVNFRKILLSKGIYLNVLESMQKHIHSPEVAESGCKMLNHLFEGSNASLDTI
AAVVPKIIAVMKSHETSLPVQLEALRAILHFIVPGMPEESREDTDSHHKLNMVKKQCFKN
DIHKLVLAALNRFIGNPGIQKCGLKVVSSIAHFPDALEMLSLEGAMDSVLHTLQMYPDDQ
EIQCLGLSLIGCLITKKNLCLGTGHLLAKILVSSLQRFKDVAEVQTKGFQTILTILELSA
SFSKLLLDHSFNLVIFHQMSSNIMEQKDQQFLNLCCKCFAKVAMDDDLKNVMLERACDQN
NSFMVECLLLLGADANQAKEATSLICRVCEKESSPKLVELLLNSGSREQDVRKALTISIG
KGDSQIISLLLRRLALDVANNSICLGGFCIGKVEPSWLGPLFPDKTSNVRKQTNIASTLA
RMVIRYQMKSAMEEGAALGSNGNFSEDVLHKFDEWTFIPDSSMDSVFAQSDDLDSEGSEG
SFLVKKKSNSISVGEFYQDLALQRCSPNLQRHSNSLGPIFDHEDLLRRKRKILSSDDSLR
SSKVQSHMRHSESISSLASEREYVTSLDLSANELRDIDALSQKCCLSGHLEHLEKLELHQ
NALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMNCIANLDVSRNDIGPSVVLDPAV
KCPTLKQFNLSYNQLSSVPENAADVVEKLEQLILEGNKISGICSPLRLKELKILNLSKNH
ISSLSENFLEACPKVESFSARMNFLAAIPFLPSSMTSLKLSQNKFTCIPEAILNLPHLRS
LDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEI
PPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHIGCKAKDIIR
FLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKIKKSDLGMQSATVGIDVKDWPIQI
RGKRKRDLVLNVWDFAGHEEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKA
RASSSPVILVGTHSDVSDEKQRKACISKITKELLNKRGFPAIRDYHFVNATEESDALAKL
RKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDQKRLLQLVREN
QLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQILTVKVEGCPK
HPKGIISRRDVEKFLSKKRRFPKNYMSQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVI
ELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYL
NWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDI
CGEGETLLKKWALYSFNDGEEHKKILLDDLMKKAEEGDLLVNPDEPRLTIPIAQIAPDLI
LADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQE
LVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVAD
GLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRA
PEVARGNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPNEFDELAIQGKLPDPVKEYG
CVPWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELTCLMRHILLPKNVIVECMVATHH
NSRNASIWLGCGHTNRGQLSFLDLNTEEYTSEEVADSRILCLALVHLPVEKESWIVSGTQ
SGTLLVINTEDEKKRHTLEKMTDSITCLYCNSFSKQSKQKNFLLVGTADGNIAIFEDKTV
KLKGAAPLKILNIGNVSTPLMCLSESTNSTERNIMWGGCGTKIFSFSNDFTIQKFIETRT
NQLFSYAAFSDSNIIAIVVDTALYVAKKNSPVVEVWDKKTEKLCELIDCVHFLRELMVKV
NKESKHKMSYSGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRVIRIIYNFCDSVRVMMT
AQLGSLKNVMLVLGYNWKSTEGTQHQKETQSCLTVWDINLPHEVQNLEKHIEVRKELAEK
MRGTSAE
NT seq
7584 nt
NT seq
+upstream
nt +downstream
nt
atggctagtggcagcagtcaggtgtgcgaggaggacgaggaaactctgaagaagttaata
gtcaggctgaacaacgtccaggaaggaaaacagatagaaacgctggtccaaatcctggag
gatctgctggtgttcacgtactccgagcacgcctccaagttatttcaaggcaaaaatatc
cacgttcctctgttgatcgtcttggactcgtatatgagagtcgcgagtgtgcagcaggtg
ggttggtcacttttatgcaaattaatagaaatctgtccaggtacaatgcaaagcttaatg
ggaccccaggatgttggaaatgattgggaattccttggtgttcaccaattgattcttaaa
atgctagcagttcacaatgccagtgtaaatctgtcaatgattggactgaagaccttagat
ctcctcctaacttcaggtaaaatcaccttgctgatattggatgaagaaagtgatattttc
ttgttaatttttgatgccttgcactcatttccaaccaatgatgaagtccagaaacttgga
tgcaaagctttacatgtgttgtttgagagagtctcagaggagcaactgactgaatttgtt
gagaacaaagattatatgatattgttaagtgcgttaaaaaattttaaagaagaagaggaa
attgtgcttcatgtgctgcattgtttacattctctagcgattccatgcaataatgtggaa
gtcctcatgagtggcaatgtcaggtgttataatattgtggtggaagctatgaaagcattc
cctttcagtgaaaaaattcaggaagtgagttgctgcttgctccataggcttacattaggt
aatttttttaatattctggtattaaacgaagtccatgagtttgtggtgaaagctgtgcag
cagtacccagagaatgcaacattacaaatctcagcactcagctgtttggcccttctcact
gagaccattttcttaaatcaagacttagaggaaaagaatgagaatcaggagaacgatgat
gagggggaagaagataaattgttttggctggaagcctgttacaaagcattaacgtggcat
agaaagaacaagcatgtgcaggaggccgcatgctgggcactaaataatctccttatgtat
caaaacagtttacatgagaagattggagatgaagaaggccatttcccagctcatagggaa
gtgatgctctccatgttgatgcattcttcatcaaaagaagttttccaggcatctgcgaat
gcactgtcaactctcttagaacaaaatgttaatttcagaaagatcctgttgtcgaaagga
atatacttgaatgttttggagtcaatgcagaagcatatacattctcctgaagtggctgaa
agtggctgtaaaatgctaaatcatctttttgaaggaagcaatgcttccctggatacaata
gcagcagtggtccccaaaataatagcagttatgaaaagtcatgagacatcattaccagtg
cagctggaggcacttcgagctattttacattttatagtgccaggcatgccagaagaatcc
agggaggatacagactctcatcataagctaaatatggttaaaaaacaatgtttcaagaat
gatattcacaaactggtcctagcagctttgaacaggttcattggaaatcctgggattcag
aaatgtggactaaaagtggtttcttctattgcacattttcctgatgcgttagagatgtta
tccctggaaggtgctatggattcggtgcttcacacactgcagatgtatccagatgaccaa
gaaattcaatgtctgggcttaagtcttataggatgcttgattacaaagaagaacttatgc
ctaggaactggacatctgctagcaaaaattctggtttccagcttacaacgatttaaggat
gttgccgaagtacagactaaaggatttcagacaatcttaacaatccttgaattgtcagca
tctttttccaagctgctgctggatcattcatttaacttagtaatattccatcagatgtct
tccaatatcatggaacaaaaggatcaacagtttctaaacctctgttgcaagtgttttgca
aaagtagctatggatgatgacttaaaaaatgtgatgctagagagagcctgtgatcagaat
aacagcttcatggttgaatgcttgcttctgttgggagcagatgccaatcaagcaaaggag
gcaacttctttaatttgtcgggtatgtgagaaagagagtagtcccaaattggtggaactc
ttattgaatagtggatctcgtgaacaagatgtacggaaagcgctgacgataagcattggg
aaaggcgacagtcagatcatcagcttgctcttacggaggctggccctggatgtggccaac
aatagcatttgccttggagggttttgtataggaaaagttgaaccttcttggcttggtcct
ttatttccagataagacttctaatgtaaggaaacaaacaaatatagcatctacactagca
agaatggtgatcagatatcagatgaaaagtgctatggaagaaggagcagccttaggcagc
aatggaaatttttctgaagatgtgctgcataaatttgatgaatggacctttattcctgat
tcttctatggacagtgtgtttgctcaaagtgatgatctggatagcgaaggaagtgaaggc
tcattccttgtgaaaaagaaatcaaattcaattagtgtaggagaattttaccaagatctt
gcattgcagcgttgttcaccaaatttgcaaaggcattccaattctttgggacccattttt
gatcatgaagatttactgaggagaaaaaggaaaatattatcttcagatgattcactcagg
tcatcaaaagttcaatcccatatgaggcattcagaaagtatttcttctctggcgtctgag
agagaatatgttacatcactagacctttcagcaaatgaactaagagatattgatgcctta
agccagaaatgctgtctaagtggtcatttggagcatcttgaaaagctggagcttcaccag
aatgcactcacgagctttccacaacagctatgtgaaactctgaagagtttgacacatttg
gacttgcacagtaataaatttacatcatttccttcttacttgttgaaaatgaattgcatt
gctaaccttgatgtctctcgaaatgacattggaccctcagtggttttagatcctgcagtg
aaatgtccaactctgaagcagttcaacctgtcatataaccagctgtcttctgttcctgag
aatgctgctgatgtggtagagaagctggagcagctcattttagaaggaaataaaatatca
ggaatatgctctcccttgagactgaaggaactgaagattttaaaccttagtaaaaatcac
atttcatccctgtcagagaacttccttgaggcttgtcctaaagtggagagtttcagtgcc
agaatgaattttcttgctgctatacctttcttgccttcttccatgacaagcctaaaatta
tctcaaaacaaatttacatgtattccagaagcaattttaaatcttccacacttgcggtct
ttagatatgagcagcaatgatattcaatatctaccaggtcctgcacactggaagtctttg
aacttaagggaactattatttagccataatcagatcagcatcctggacttgagtgaaaaa
gcatatttatggtctagagtagagaaactacatctttctcacaataaactgaaagagatt
cctcctgagattggctgtcttgaaaatctgacatctctggatgtcagttacaacttggaa
ctaagatcctttcccaatgaaatggggaaattaagcaaaatatgggaccttcctttggat
gaactacgtcttaactttgattttaaacacataggatgtaaagccaaagacatcataagg
tttcttcaacagcggttaaaaaaggctgtaccctataaccgaatgaaactaatgattgtg
ggaaatactgggagtggtaaaaccaccttattgcaacagttaatgaaaatcaagaaatca
gatcttggaatgcagagtgccacagttggcatagatgtgaaagactggcctatccaaata
agaggcaaaagaaagagagacctcgttctaaatgtgtgggattttgcaggtcatgaggaa
ttctatagtacgcatccccattttatgacccagcgagcattgtatcttgctgtctatgac
ctcagcaaaggacaggctgaagttgatgccatgaagccttggctctttaatataaaggct
cgtgcttcttcttctcctgtgatacttgttggcacacattcggatgtttctgatgagaag
cagcgcaaagcctgcataagtaaaatcaccaaggaactcttgaataagcgagggttccct
gccattcgagattaccactttgtgaatgccactgaggaatctgatgctttggcaaaactt
cggaaaaccatcataaatgagagccttaacttcaagatccgagatcagcctgttgttgga
cagctgatcccagattgctatgttgaacttgagaaaatcattttatcagagcgtaaaaat
gtgccaattgaatttcctgtaattgaccagaaacgattattacaacttgtgagagaaaat
cagctgcagttagatgaaaatgagcttcctcatgcagttcactttctaaatgaatcagga
gtccttcttcattttcaagacccagcactgcagttaagtgacttgtattttgtggaaccc
aagtggctttgtaaaatcatggcacagattttgacagtgaaagtggaaggttgtccaaaa
caccctaagggaattatttcacgtagagatgtggaaaaatttctttcaaagaaaaggaga
tttccaaagaactacatgtcacagtattttaagctcctggaaaaattccagattgctttg
ccaataggagaagaatatttgctggttccaagcagtttgtctgaccacaggcctgtgata
gagcttccccattgtgagaactctgaaattatcatccgactgtatgaaatgccttatttt
ccaatgggattttggtcgagattaatcaatcgattacttgagatttcaccttacatgctt
tcagggagagaacgagcacttcgcccaaacagaatgtattggcgacaaggcatctacttg
aattggtctcctgaagcttattgtctggtaggatctgaagtcttagacaatcacccagag
agtttcttgaaaattacagttccttcttgtagaaaaggctgtattcttttgggccaagtt
gtggaccacattgattctctcatggaagaatggtttcctgggttgttggagattgatatt
tgtggtgaaggagaaactctattgaagaaatgggcattgtatagttttaatgatggtgaa
gaacataaaaaaatcttacttgatgacttgatgaagaaagcagaggaaggagatctgtta
gtaaatccagatgaaccaaggctcaccattccaatagctcagattgcccctgacttgatt
ttggctgacctgcctagaaatattatgttgaataatgatgagttggaatttgaacaagcg
ccagagtttctcctaggtgatggcagttttggatcagtttatcgagcagcctatgaagga
gaagaagtggctgtgaagatttttaataagcatacatcacttaggctgttaagacaagag
ctggtggtgctttgccacctccaccaccccagtttgatatctttgctggcagcggggatt
cgtcccaggatgttggtgatggagttagcctccaagggttccttggatcgcctgcttcag
caagacaaagccagcctcaccagaaccctacagcacaggattgcactccatgtggctgat
ggtttgagatacctccactcagccatgatcatataccgagacttgaagccccacaatgtg
ctgcttttcaccctgtatcccaatgctgccatcattgcaaagattgctgactacggcatt
gctcagtactgctgtagaatggggataaaaacgtcagagggcacaccagggtttcgtgca
cctgaagttgccagaggaaacgtcatttataaccaacaggctgatgtttattcatttggt
ttgctactctatgacattttgacaactggaggaagaatagtagagggtttgaagtttcca
aatgagtttgatgaattagcaatacaaggaaaattacctgatccagttaaagaatatggt
tgtgtcccatggcctatggttgagaaattaattaaaaagtgtttgaaagaaaatcctcaa
gaaaggcctacttctgcacaggtctttgacattttgaattcagctgagttaacctgtctg
atgagacacattttattacctaaaaatgttattgttgaatgcatggttgctacacatcac
aacagcaggaatgcgagcatttggctgggctgtgggcacaccaacagaggacagctctca
tttctagatttaaatactgaagaatacacttctgaggaagttgctgatagcagaatattg
tgcttagccttggtgcatcttcctgttgaaaaggaaagctggattgtgtctgggacacag
tctggtactctcctggtcatcaatactgaagatgagaaaaagagacataccctagaaaag
atgactgattctatcacttgtttgtattgcaattccttttccaagcaaagcaaacaaaaa
aattttcttttggttggaactgctgatggcaatatagcaatttttgaagataagacagtt
aagcttaaaggagctgctcctttgaagatactaaatataggaaatgtcagcactccattg
atgtgtttgagtgaatccacaaattcaacagaaagaaatataatgtggggaggatgtggc
acaaagattttctccttttctaatgattttaccattcagaaattcattgagacaaggaca
aatcaactattttcttatgcagctttcagtgattccaacatcatagcaatagtggtggac
acggctctctatgttgctaagaaaaacagccctgtcgtggaagtgtgggataagaaaact
gaaaaactctgcgaactaatagactgtgtgcactttttacgggagttaatggtaaaagta
aacaaggaatcaaaacacaaaatgtcttattctgggagggtgaaaactctctgccttcag
aagaacactgctctctggataggaactggaggaggccatattttactcctggatctttca
actcgtcgagttatacgtataatttacaacttttgtgattcagtcagagtcatgatgaca
gcacagctaggaagccttaaaaatgtcatgctggttttgggctacaactggaaaagtact
gaaggtacacaacaccagaaagagacacaatcttgcctgactgtttgggacatcaatctt
ccacatgaagtgcaaaatttagaaaaacacattgaagtgagaaaagaattagctgaaaaa
atgagaggaacatctgctgaataa
DBGET
integrated database retrieval system
