KEGG   COMPOUND: C12508Help
Entry
C12508                      Compound                               

Name
Nateglinide
Formula
C19H27NO3
Exact mass
317.1991
Mol weight
317.4226
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BX Other blood glucose lowering drugs, excl. insulins
     A10BX03 Nateglinide
      D01111  Nateglinide (JP17/USAN/INN)
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Antidiabetic Agents
   Nateglinide
    D01111  Nateglinide (JP17/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   396  Antidiabetic agents
    3969  Others
     D01111  Nateglinide (JP17/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC (CFTR/MRP) subfamily
    ABCC8 (sulfonylurea receptor 1)
     Nateglinide
      D01111  Nateglinide (JP17/USAN/INN)
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP2C9
   Nateglinide
    D01111  Nateglinide (JP17/USAN/INN)
  CYP2D6
   Nateglinide
    D01111  Nateglinide (JP17/USAN/INN)
  CYP3A4
   Nateglinide
    D01111  Nateglinide (JP17/USAN/INN)
  CYP3A5
   Nateglinide
    D01111  Nateglinide (JP17/USAN/INN)
  CYP3A7
   Nateglinide
    D01111  Nateglinide (JP17/USAN/INN)
 Transporter substrates
  SLCO1B1
   Nateglinide
    D01111  Nateglinide (JP17/USAN/INN)
  SLCO1B3
   Nateglinide
    D01111  Nateglinide (JP17/USAN/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01111  Nateglinide
  D01111  Nateglinide tablets
Antidiabetics [br08361.html]
 D01111
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D01111
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D01111
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D01111
BRITE hierarchy
Other DBs
CAS: 
105816-04-4
PubChem: 
ChEBI: 
ChEMBL: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        23
            1   C8x C    13.8152  -13.4012
            2   C8x C    13.8152  -14.8022
            3   C8x C    15.0315  -15.5027
            4   C8x C    16.2406  -14.8022
            5   C8y C    16.2406  -13.4012
            6   C8x C    15.0315  -12.7007
            7   C1b C    17.4452  -12.7007
            8   C1c C    18.6552  -13.3940
            9   C6a C    19.8652  -12.6936
            10  O6a O    21.0794  -13.3927
            11  O6a O    19.8635  -11.2926
            12  N1b N    18.6582  -14.7951
            13  C5a C    19.8732  -15.4930
            14  C1y C    19.8762  -16.8941
            15  O5a O    21.0850  -14.7898
            16  C1x C    18.6664  -17.5910
            17  C1x C    18.6696  -18.9921
            18  C1y C    19.8844  -19.6899
            19  C1x C    21.0962  -18.9866
            20  C1x C    21.0932  -17.5856
            21  C1c C    19.8874  -21.0700
            22  C1a C    21.0958  -21.7641
            23  C1a C    18.6710  -21.7759
BOND        24
            1     5   6 2
            2     8  12 1 #Down
            3     6   1 1
            4    12  13 1
            5    14  13 1 #Down
            6     5   7 1
            7    13  15 2
            8     1   2 2
            9     7   8 1
            10    2   3 1
            11    8   9 1
            12    3   4 2
            13   14  16 1
            14   16  17 1
            15   17  18 1
            16   18  19 1
            17   19  20 1
            18   20  14 1
            19    9  10 1
            20    4   5 1
            21    9  11 2
            22   18  21 1 #Up
            23   21  22 1
            24   21  23 1

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