KEGG   DRUG: CapsaicinHelp
Entry
D00250                      Drug                                   

Name
Capsaicin (JAN/USP);
Zostrix (TN)
Product
Formula
C18H27NO3
Exact mass
305.1991
Mol weight
305.4119
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG01675  Local anesthetic
 DG01675  Local anesthetic
Remark
Same as: 
ATC code: 
Activity
Analgesic (topical), Transient receptor potential (TRP) channel agonist
Comment
Antineuralgic, specific pain syndromes, topical
Target
TRPV1 [HSA:7442] [KO:K05222]
  Pathway
Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
   M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
    M02AB Capsaicin and similar agents
     M02AB01 Capsaicin
      D00250  Capsaicin (JAN/USP)
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01B ANESTHETICS, LOCAL
    N01BX Other local anesthetics
     N01BX04 Capsaicin
      D00250  Capsaicin (JAN/USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   Capsaicin
    D00250  Capsaicin (JAN/USP)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Related to voltage-gated cation channels
   Transient receptor potential family, TRPV (Vanilloid)
    transient receptor potential cation channel, subfamily V, member 1 (TRPV1)
     Capsaicin
      D00250  Capsaicin (JAN/USP)
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D00250
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00250
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00250
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D00250
BRITE hierarchy
Other DBs
CAS: 
404-86-4
PubChem: 
ChEBI: 
ChEMBL: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        22
            1   C8y C    14.3789  -14.5250
            2   C8x C    13.1676  -15.2238
            3   C8x C    14.3789  -13.1272
            4   C1b C    15.5904  -15.2238
            5   C8y C    11.9504  -14.5250
            6   C8x C    13.1676  -12.4226
            7   N1b N    16.8017  -14.5250
            8   C8y C    11.9504  -13.1272
            9   O2a O    10.7391  -15.2238
            10  C5a C    18.0189  -15.2179
            11  O1a O    10.7391  -12.4226
            12  C1a C     9.5219  -14.5307
            13  C1b C    19.2244  -14.5250
            14  O5a O    18.0189  -16.6216
            15  C1b C    20.4357  -15.2179
            16  C1b C    21.6529  -14.5190
            17  C1b C    22.8644  -15.2179
            18  C2b C    24.0816  -14.5190
            19  C2b C    25.2929  -15.2179
            20  C1c C    26.5042  -14.5190
            21  C1a C    27.7214  -15.2122
            22  C1a C    26.5042  -13.1156
BOND        22
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     5   9 1
            9     7  10 1
            10    8  11 1
            11    9  12 1
            12   10  13 1
            13   10  14 2
            14   13  15 1
            15   15  16 1
            16   16  17 1
            17   17  18 1
            18   18  19 2
            19   19  20 1
            20   20  21 1
            21   20  22 1
            22    6   8 1

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