KEGG   DRUG: Enprofylline
Entry
D04006                      Drug                                   
Name
Enprofylline (USAN/INN)
Formula
C8H10N4O2
Exact mass
194.0804
Mol weight
194.1906
Structure
Simcomp
Class
Respiratory system agent
 DG01616  Xanthine derivative
  DG01609  Xanthine-type bronchodilator
Efficacy
Bronchodilator, Adenosine receptor antagonist
Comment
Xanthine derivative
Target
  Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
Interaction
Brite
Drug groups [BR:br08330]
 Respiratory system agent
  DG01616  Xanthine derivative
   DG01609  Xanthine-type bronchodilator
    D04006  Enprofylline
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adenosine
    ADORA1
     D04006  Enprofylline (USAN/INN)
    ADORA2
     D04006  Enprofylline (USAN/INN)
 Enzymes
  Hydrolases (EC3)
   Phosphodiesterases
    PDE
     D04006  Enprofylline (USAN/INN)
Other DBs
CAS: 41078-02-8
PubChem: 17398000
ChEBI: 126237
LigandBox: D04006
NIKKAJI: J16.542E
LinkDB
KCF data

ATOM        14
            1   N4x N    14.2100  -16.5200
            2   C8y C    14.2100  -17.9200
            3   N4y N    13.0200  -18.6200
            4   C8y C    11.7600  -17.9200
            5   C8y C    11.7600  -16.5200
            6   C8y C    13.0200  -15.8200
            7   O5x O    13.0200  -14.4200
            8   O5x O    15.4000  -18.6200
            9   N5x N    10.4300  -18.3400
            10  C8x C     9.6600  -17.2200
            11  N4x N    10.4300  -16.1000
            12  C1b C    13.0200  -20.0200
            13  C1b C    11.8300  -20.7200
            14  C1a C    11.8300  -22.1200
BOND        15
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     6   7 2
            8     2   8 2
            9     4   9 1
            10    9  10 2
            11   10  11 1
            12    5  11 1
            13    3  12 1
            14   12  13 1
            15   13  14 1

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