| Entry |
|
|---|
| Name |
Phenylephrine tartrate;
L-Phenylephrine tartrate;
Boraline (TN) |
|---|
| Formula |
C9H13NO2. C4H6O6
|
|---|
| Exact mass |
317.1111
|
|---|
| Mol weight |
317.2919
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
|
|---|
| Remark |
| Product (DG00215): | D00511<JP/US> |
|
|---|
| Efficacy |
Antihypotensive, Vasoconstrictor, alpha1-Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
See [DR: D08966]
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA06 Phenylephrine
D08366 Phenylephrine tartrate
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AX Other agents for treatment of hemorrhoids and anal fissures for topical use
C05AX06 Phenylephrine
D08366 Phenylephrine tartrate
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AA Sympathomimetics, plain
R01AA04 Phenylephrine
D08366 Phenylephrine tartrate
R01AB Sympathomimetics, combinations excl. corticosteroids
R01AB01 Phenylephrine
D08366 Phenylephrine tartrate
R01B NASAL DECONGESTANTS FOR SYSTEMIC USE
R01BA Sympathomimetics
R01BA03 Phenylephrine
D08366 Phenylephrine tartrate
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01F MYDRIATICS AND CYCLOPLEGICS
S01FB Sympathomimetics excl. antiglaucoma preparations
S01FB01 Phenylephrine
D08366 Phenylephrine tartrate
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA05 Phenylephrine
D08366 Phenylephrine tartrate
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00215 Phenylephrine
D08366 Phenylephrine tartrate
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG00215 Phenylephrine
D08366 Phenylephrine tartrate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D08366 Phenylephrine tartrate
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00215 Phenylephrine
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG00215 Phenylephrine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 22
1 O6a O 20.9729 -16.4548
2 C6a C 22.1809 -15.7573
3 C1c C 23.3891 -16.4548
4 C1c C 24.5971 -15.7573
5 C6a C 25.8052 -16.4548
6 O6a O 27.0133 -15.7573
7 O6a O 22.1809 -14.3626
8 O6a O 25.8052 -17.8497
9 O1a O 23.3891 -17.8496
10 O1a O 24.5971 -14.3624
11 C8y C 10.7100 -16.4500
12 C8x C 10.7100 -17.8500
13 C8x C 11.9000 -18.5500
14 C8x C 13.0900 -17.8500
15 C8y C 13.0900 -16.4500
16 C8x C 11.9000 -15.7500
17 O1a O 9.4500 -15.7500
18 C1c C 14.3500 -15.7500
19 C1b C 15.5400 -16.4500
20 O1a O 14.3500 -14.3500
21 N1b N 16.7300 -15.7500
22 C1a C 17.9200 -16.4500
BOND 21
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 2 7 2
7 5 8 2
8 3 9 1 #Up
9 4 10 1 #Up
10 11 12 2
11 12 13 1
12 13 14 2
13 14 15 1
14 15 16 2
15 11 16 1
16 11 17 1
17 15 18 1
18 18 19 1
19 18 20 1 #Down
20 19 21 1
21 21 22 1
|
|---|
