Danio rerio (zebrafish): 567021
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Entry
567021 CDS
T01004
Symbol
ern2
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE2 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre04140
Autophagy - animal
dre04141
Protein processing in endoplasmic reticulum
dre04210
Apoptosis
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
567021 (ern2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
567021 (ern2)
09143 Cell growth and death
04210 Apoptosis
567021 (ern2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dre01001
]
567021 (ern2)
Enzymes [BR:
dre01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
567021 (ern2)
Protein kinases [BR:
dre01001
]
Serine/threonine kinases: Other
IRE family
567021 (ern2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ribonuc_2-5A
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
Miga
Motif
Other DBs
NCBI-GeneID:
567021
NCBI-ProteinID:
XP_001919350
ZFIN:
ZDB-GENE-090312-15
Ensembl:
ENSDARG00000058475
UniProt:
A0A8M1QQI8
LinkDB
All DBs
Position
1:complement(9169271..9195936)
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AA seq
930 aa
AA seq
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MRIMKNWTQMLLLLVCFAGIVSQCEGGSSVSLPESLLFVSTLDGSLHAVSKQTGDIKWTL
KEDPIIQVPEYFQEPGFLPDPNDGSLYVLGGKRKEGLMKLPFTIQELVQSSPCRSSDGVL
YTGKKQDTWFVVDPQTGEKQTSLSTSSSDSICPSAPLLYIGRTEYMITMYDTKTQELRWN
ATYNDYSAPLYDDKKYEYKMSHFASSGDGLVVTVDRDSGEVLWMQKFDSPVAGFYLWSQD
SLRRAPHLTVATETLRYLTFTAENTQSHTMKWTYQFTKESHSTKTQLVPTLYVGKTESHL
YASASLVHQGVAIVPKGLTLARIEGPMTAGVTMGNGRPECEITPSTDVKYPPGSSSSLQN
QWLLIGHHEIPPLAHTTMLRDFPENLQRSGDVIPPRGSGSSYRSPSHPLPPVRKQSSSPV
LPDSLSSEPMTVLVVTLLLGAWITFLLTHKWPVKKSQRSEEPVDSTPLSGLTNYSASTEL
NTPPSTSSYSNSSRSEKTSSVASNQTQPFSSKDSASVTAASQSQNEQADVVEVGKISFSP
TEVLGHGTEGTFVFRGHFDGRRVAVKRILPECVEFAEREVQLLRESDEHPNVIRYFCTER
DRQFTYIAIELCAATLQQYVEDPSCPHSELNPVSLLEQTMCGLSHLHSLNIVHRDLKPRN
ILLSLPGALGRVRALISDFGLCKKLPDGRHSFSLRSGIPGTEGWIAPELLINAPKGNPTS
AVDIFSAGCVFYYVTSKGQHPFGDTLRRQANILSGVYNLDHFMEDIHEDVIGRDLIERMI
SAEPESRPSAASILKHPFFWSPEKQLQFFQDVSDRIEKEPTESPIVARLENSGRSVVRTN
WRMHISAPLQADLRKFRTYKGNSVRDLLRAMRNKKHHYHELPPEVQSTLGEVPDGFVAYF
TSRFPRLLLHTHTALSICAPERPFHPYYHH
NT seq
2793 nt
NT seq
+upstream
nt +downstream
nt
atgaggattatgaagaactggacacagatgctgctgttgctggtttgcttcgctggaatc
gtgtctcagtgtgagggaggaagctccgtctctctgcccgagtctctgctctttgtttct
acactggatggaagtctgcatgccgtcagcaaacagaccggagacatcaaatggacactg
aaggaagatcccattatacaggttcccgagtatttccaagagccaggctttttaccagac
cccaatgacggaagtctgtatgttctcggaggaaagaggaaagaaggtctgatgaaactg
ccattcactattcaagagctggtgcagtcgtctccctgcaggagctcagatggagtactc
tacaccggtaaaaaacaggacacctggtttgtggtcgatcctcagacaggtgaaaaacag
acaagtttgagcacctcgtcttcagactccatctgtccctctgcacctctgttgtacatc
ggtcgcacagaatatatgatcaccatgtatgacacgaagactcaggagctccgctggaat
gccacatacaacgattactcagctcctctatatgacgacaaaaaatatgaatataagatg
tcgcactttgcatcgagtggcgatggtctggtggttacggtggatcgagactctggcgag
gttttgtggatgcagaaatttgattctccggtggctggattttacttgtggagtcaggac
agtctccgtcgagcccctcatctgaccgtcgcaacagaaaccctgcgctatctgaccttc
accgcagaaaacacacagtcccacaccatgaagtggacctaccagttcacaaaggagagc
cacagcacgaagactcagctagttcccactctgtatgttgggaagacggagtctcatctg
tatgcttctgcctcccttgtccatcaaggtgtcgcaatagtgcctaagggtctcactctt
gcacgcattgaggggccgatgacagcaggcgtcacaatgggtaatggacggcctgagtgc
gagatcacacccagcactgacgtcaaatatccaccaggaagcagcagctctctgcagaat
cagtggctgctcattggtcaccatgaaatccctcctctggctcacaccaccatgttgaga
gatttcccagagaacctgcagcgctctggtgatgtcatcccacctcgaggatccggctct
tcttaccgctctccctctcacccattgccaccagttaggaagcagagctcttctccagtg
ctgccagactcgctgagctctgagcccatgacagtgctggtggtgacgctgctgctagga
gcctggatcaccttcctgctcacacacaaatggcctgtaaaaaaatcccaaagatctgaa
gagccagtggactccaccccactttctggtctgaccaattacagcgcttctacagaactg
aacactccgccctcaacatcatcttacagcaacagcagtcgctcagaaaagaccagttct
gttgcatccaatcaaactcagccattctcaagcaaagactccgcctctgtaacagcagcc
agccaatcacagaatgaacaggctgacgtggtggaagttggtaaaatctctttcagtccc
actgaggtgttgggtcatgggacagaaggaaccttcgtgtttcggggtcattttgacggt
cggcgtgtggcggtgaagcgaatcctgccggagtgtgtggagtttgcagagcgagaggtt
caacttctgcgggaatcagatgaacatcccaatgtgatccgttacttctgcacagagcgg
gacagacagttcacttacattgccatagagctgtgtgctgcaacactccagcagtatgta
gaagacccgagctgtcctcactcagagctgaacccggtgtccctgctggagcagaccatg
tgtggcctcagtcacctgcactccctcaacatcgtccacagggatttaaagcccaggaat
attttgctgtctctgcccggggcactgggtcgagtgcgggcgctcatctcagatttcggc
ttgtgtaagaagcttccagatggtcggcacagtttcagcctacgctccgggatacctgga
accgaaggctggatcgcccctgaattactcataaacgctccgaaagggaaccctacgagt
gcggtggacattttttctgccggatgtgtgttttattatgtgacgtctaaaggacagcat
ccgttcggtgacactctgcggcgtcaggctaacatcctctctggagtctataacctcgat
cacttcatggaggatatacatgaggacgtgattggcagagatctgatcgagcggatgatc
agtgcagagccagagagccgtccttcagcagcgtcaattcttaaacaccccttcttctgg
agtccagagaaacagctgcagttctttcaggacgtcagtgacaggattgagaaggagcct
acagaaagtcctatagtggctcgtctggaaaattctggcagatctgtcgtaagaaccaac
tggaggatgcacatctcagcgccgctgcaggctgatcttagaaaatttcgtacatataaa
ggaaactcagtgagagacctgcttagagcaatgaggaataaaaaacaccattatcacgag
ctcccgccggaggttcagtcgactctcggtgaagtccccgatggctttgtggcgtatttc
acctcacggttcccccggttactgcttcacacgcacacagcactcagcatctgtgccccc
gagagaccctttcacccgtactatcatcactga
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