Oxidoreductases;
Acting on a peroxide as acceptor;
Peroxidases

Reactive-Blue-5:hydrogen-peroxide oxidoreductase

Reactive Blue 5 + 2 H2O2 = phthalate + 2,2'-disulfonyl azobenzene + 3-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + 2 H2O [RN:R10915]

R10915

Reactive Blue 5 [CPD:C19693];
H2O2 [CPD:C00027]

Heme proteins with proximal histidine secreted by basidiomycetous fungi and eubacteria. They are similar to EC 1.11.1.16 versatile peroxidase (oxidation of Reactive Black 5, phenols, veratryl alcohol), but differ from the latter in their ability to efficiently oxidize a number of recalcitrant anthraquinone dyes, and inability to oxidize Mn(II). The model substrate Reactive Blue 5 is converted with high efficiency via a so far unique mechanism that combines oxidative and hydrolytic steps and leads to the formation of phthalic acid. Bacterial TfuDyP catalyses sulfoxidation.

EC 1.11.1.19 created 2011, modified 2015

1  [PMID:10049859]

Kim SJ, Shoda M

Purification and characterization of a novel peroxidase from Geotrichum candidum  dec 1 involved in decolorization of dyes.

Appl. Environ. Microbiol. 65 (1999) 1029-35.

2  [PMID:15313183]

Sugano Y, Ishii Y, Shoda M

Role of H164 in a unique dye-decolorizing heme peroxidase DyP.

Biochem. Biophys. Res. Commun. 322 (2004) 126-32.

3  [PMID:17654547]

Zubieta C, Joseph R, Krishna SS, McMullan D, Kapoor M, Axelrod HL, Miller MD, Abdubek P, Acosta C, Astakhova T, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Elsliger MA, Feuerhelm J, Grzechnik SK, Hale J, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Kumar A, Marciano D, Morse AT, Murphy KD, Nigoghossian E, Okach L, Oommachen S, Reyes R, Rife CL, Schimmel P, Trout CV, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA

Identification and structural characterization of heme binding in a novel dye-decolorizing peroxidase, TyrA.

Proteins. 69 (2007) 234-43.

4  [PMID:19009358]

Sugano Y, Matsushima Y, Tsuchiya K, Aoki H, Hirai M, Shoda M

Degradation pathway of an anthraquinone dye catalyzed by a unique peroxidase DyP  from Thanatephorus cucumeris Dec 1.

Biodegradation. 20 (2009) 433-40.

5  [PMID:19099183]

Sugano Y

DyP-type peroxidases comprise a novel heme peroxidase family.

Cell. Mol. Life. Sci. 66 (2009) 1387-403.

6  [PMID:19801472]

Ogola HJ, Kamiike T, Hashimoto N, Ashida H, Ishikawa T, Shibata H, Sawa Y

Molecular characterization of a novel peroxidase from the cyanobacterium Anabaena sp. strain PCC 7120.

Appl. Environ. Microbiol. 75 (2009) 7509-18.

7  [PMID:19967355]

van Bloois E, Torres Pazmino DE, Winter RT, Fraaije MW

A robust and extracellular heme-containing peroxidase from Thermobifida fusca as  prototype of a bacterial peroxidase superfamily.

Appl. Microbiol. Biotechnol. 86 (2010) 1419-30.

[tfu:Tfu_3078]

8  [PMID:19756587]

Liers C, Bobeth C, Pecyna M, Ullrich R, Hofrichter M

DyP-like peroxidases of the jelly fungus Auricularia auricula-judae oxidize nonphenolic lignin model compounds and high-redox potential dyes.

Appl. Microbiol. Biotechnol. 85 (2010) 1869-79.

9  [PMID:20495915]

Hofrichter M, Ullrich R, Pecyna MJ, Liers C, Lundell T

New and classic families of secreted fungal heme peroxidases.

Appl. Microbiol. Biotechnol. 87 (2010) 871-97.