| Entry |
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| Name |
lactate 2-monooxygenase;
lactate oxidative decarboxylase;
lactate oxidase;
lactic oxygenase;
lactate oxygenase;
lactic oxidase;
L-lactate monooxygenase;
lactate monooxygenase;
L-lactate-2-monooxygenase
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| Class |
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
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| Sysname |
(S)-lactate:oxygen 2-oxidoreductase (decarboxylating)
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| Reaction(IUBMB) |
(S)-lactate + O2 = acetate + CO2 + H2O [RN: R00319]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
A flavoprotein (FMN).
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| History |
EC 1.13.12.4 created 1961 as EC 1.1.3.2, transferred 1972 to EC 1.13.12.4
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| Pathway |
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| Orthology |
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| Genes |
AFM: | | CCR: | | LSA: | | MAV: | | MSM: | | MMC: | | MKM: | | MJL: | | SEN: | | RXY: | | DGE: | | TTH: | | PTO: | |
» show all
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| Reference |
1 |
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| Authors |
Hayaishi, O. and Sutton, W.B. |
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| Title |
Enzymatic oxygen fixation into acetate concomitant with the enzymatic decarboxylation of L-lactate. |
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| Journal |
J. Am. Chem. Soc. 79 (1957) 4809-4810. |
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| Reference |
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| Authors |
SUTTON WB. |
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| Title |
Mechanism of action and crystallization of lactic oxidative decarboxylase from Mycobacterium phlei. |
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| Journal |
J. Biol. Chem. 226 (1957) 395-405. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 9028-72-2 |
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| LinkDB |
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