| Entry |
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| Name |
pyrimidine-deoxynucleoside 1'-dioxygenase;
deoxyuridine-uridine 1'-dioxygenase
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| Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
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| Sysname |
2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1'-hydroxylating)
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| Reaction(IUBMB) |
2'-deoxyuridine + 2-oxoglutarate + O2 = uracil + 2-deoxyribonolactone + succinate + CO2 [RN: R02486]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Requires Fe(II) and ascorbate. cf. EC 1.14.11.3, pyrimidine-deoxynucleoside 2'-dioxygenase.
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| History |
EC 1.14.11.10 created 1989, modified 2002
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| Reference |
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| Authors |
Stubbe J. |
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| Title |
Identification of two alpha-ketoglutarate-dependent dioxygenases in extracts of Rhodotorula glutinis catalyzing deoxyuridine hydroxylation. |
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| Journal |
J. Biol. Chem. 260 (1985) 9972-5. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 98865-52-2 |
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| LinkDB |
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