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Entry
EC 1.14.11.25               Enzyme                                 

Name
mugineic-acid 3-dioxygenase;
IDS2
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
BRITE hierarchy
Sysname
mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)
Reaction(IUBMB)
(1) mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2 [RN:R07186];
(2) 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2 [RN:R07187]
Reaction(KEGG)
Substrate
mugineic acid [CPD:C15500];
2-oxoglutarate [CPD:C00026];
O2 [CPD:C00007];
2'-deoxymugineic acid [CPD:C15485]
Product
3-epihydroxymugineic acid [CPD:C15501];
succinate [CPD:C00042];
CO2 [CPD:C00011];
3-epihydroxy-2'-deoxymugineic acid [CPD:C15502]
Comment
Requires iron(II).
History
EC 1.14.11.25 created 2005
Orthology
K18054  
2'-deoxymugineic-acid 2'-dioxygenase / mugineic-acid 3-dioxygenase
Genes
OSA: 
DOSA: 
Os07t0169600-01(Os07g0169600)
OBR: 
BDI: 
SBI: 
ZMA: 
100282204(idc1)
SITA: 
Taxonomy
Reference
1  [PMID:11117263]
  Authors
Nakanishi H, Yamaguchi H, Sasakuma T, Nishizawa NK, Mori S.
  Title
Two dioxygenase genes, Ids3 and Ids2, from Hordeum vulgare are involved in the biosynthesis of mugineic acid family phytosiderophores.
  Journal
Plant. Mol. Biol. 44 (2000) 199-207.
  Sequence
Reference
2  [PMID:8061321]
  Authors
Okumura N, Nishizawa NK, Umehara Y, Ohata T, Nakanishi H, Yamaguchi T, Chino M, Mori S.
  Title
A dioxygenase gene (Ids2) expressed under iron deficiency conditions in the roots of Hordeum vulgare.
  Journal
Plant. Mol. Biol. 25 (1994) 705-19.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
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