KEGG ENZYME: 1.7.3.5

ENZYME: 1.7.3.5

Entry

EC 1.7.3.5 Enzyme

Name

3-aci-nitropropanoate oxidase;
propionate-3-nitronate oxidase

Class

Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With oxygen as acceptor

Sysname

3-aci-nitropropanoate:oxygen oxidoreductase

Reaction(IUBMB)

3-aci-nitropropanoate + O2 + H2O = 3-oxopropanoate + nitrite + H2O2 [RN:R01609]

Reaction(KEGG)

R01609

Substrate

3-aci-nitropropanoate [CPD:C03071];
O2 [CPD:C00007];
H2O [CPD:C00001]

Product

3-oxopropanoate [CPD:C00222];
nitrite [CPD:C00088];
H2O2 [CPD:C00027]

Comment

A flavoprotein (FMN). The primary products of the enzymic reaction are probably the nitropropanoate free radical and superoxide. Also acts, more slowly, on 4-aci-nitrobutanoate.

History

EC 1.7.3.5 created 1990

Reference

1 [PMID:3667582]

Authors

Porter DJ, Bright HJ.

Title

Propionate-3-nitronate oxidase from Penicillium atrovenetum is a flavoprotein which initiates the autoxidation of its substrate by O2.

Journal

J. Biol. Chem. 262 (1987) 14428-34.

Other DBs

ExplorEnz - The Enzyme Database:

1.7.3.5

IUBMB Enzyme Nomenclature:

1.7.3.5

ExPASy - ENZYME nomenclature database:

1.7.3.5

BRENDA, the Enzyme Database:

1.7.3.5

CAS:

111940-52-4

LinkDB

DBGET integrated database retrieval system